scholarly journals Rapid Sequencing and Characterization of Pathogens in Hospital-Acquired Infections

2012 ◽  
Vol 138 (suppl 2) ◽  
pp. A234-A234
Author(s):  
Sarah Mahoney ◽  
Sarah Gruszka
Keyword(s):  
Hospital Acquired Infections ◽  
Hospital Acquired

scholarly journals Characterization of the Enterobacter Phage vB_EclM_CIP9

2020 ◽  
Vol 9 (13) ◽  
Author(s):  
Klara Wang ◽  
Marielou G. Tamayo ◽  
Tiffany V. Penner ◽  
Bradley W. M. Cook ◽  
Deborah A. Court ◽  
...  
Keyword(s):  
Enterobacter Cloacae ◽  
Opportunistic Pathogen ◽  
Multidrug Resistant ◽  
Open Reading Frames ◽  
Resistant Isolate ◽  
Content Type ◽  
Hospital Acquired Infections ◽  
Hospital Acquired ◽  
Reading Frames

Enterobacter cloacae is an opportunistic pathogen that causes hospital-acquired infections in immunocompromised patients. Here, we describe vB_EclM_CIP9, a novel Enterobacter phage that infects a multidrug-resistant isolate of E. cloacae. Phage vB_EclM_CIP9 is a myovirus that has a 174,924-bp genome, with 296 predicted open reading frames.

Characterization of 2 Klebsiella pneumoniae carbapenemase–producing Enterobacterales isolated from canine rectal swabs

2021 ◽  
pp. 104063872110655
Author(s):  
Stephen D. Cole ◽  
Shelley C. Rankin
Keyword(s):  
Klebsiella Pneumoniae ◽  
Companion Animals ◽  
E Coli ◽  
Hospital Acquired Infections ◽  
Klebsiella Pneumoniae Carbapenemase ◽  
Rectal Swabs ◽  
Life Threatening ◽  
Hospital Acquired ◽  
Yorkshire Terrier

Globally, carbapenemase-producing Enterobacterales (CPE) cause life-threatening, hospital-acquired infections in people, and have been reported recently among veterinary patients. Organisms that produce a Klebsiella pneumoniae carbapenemase (KPC) are one of the most common CPE isolated from people but have been reported only rarely in animals. We characterized 2 KPC-producing Enterobacterales isolated from companion animal rectal swabs during the response to an outbreak caused by a strain of blaNDM-5 Escherichia coli. Both isolates were characterized by whole-genome sequencing (WGS) and analysis. The first isolate (case A) was from an immunosuppressed 6-y-old Yorkshire Terrier and was identified as E. coli (ST372) with a blaKPC-18 gene and an IncFII plasmid. The second isolate (case B) was from a 3-y-old Labrador Retriever with acute diarrhea and was identified as Citrobacter koseri with a blaKPC-2 gene, multiple plasmids (ColRNAI, pKPC-CAV1193), and a putative enterotoxin gene ( senB). Further research is needed to determine what role animals might play in the epidemiology of CPE in communities. It is imperative that all CPE isolated from companion animals be fully characterized by WGS and the associated case examined. All veterinary isolates should be sequenced and shared for surveillance, monitoring, and investigation purposes.

scholarly journals Characterization of hospital acquired infections in teritaty care teaching hospital, Kathmandu

2020 ◽  
Vol 101 ◽  
pp. 281
Author(s):  
B.P. Rijal ◽  
S. Maharjan ◽  
N. Giri ◽  
O. Shrestha ◽  
S. Shrestha ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Care Teaching ◽  
Hospital Acquired Infections ◽  
Hospital Acquired

scholarly journals Characterization of hospital-acquired infections in a University Hospital in Colombia: January 2005 - July 2009

2010 ◽  
Vol 14 ◽  
pp. e260-e261
Author(s):  
J.G. Jiménez ◽  
J.K. Balparda ◽  
D.M. Castrillón ◽  
S.Y. Díaz ◽  
J.A. Echeverri ◽  
...  
Keyword(s):  
University Hospital ◽  
Hospital Acquired Infections ◽  
Hospital Acquired

Characterization of Electric Fields Generated by Electricidal Coatings for Biofilm-Resistant Catheters

2021 ◽  
Author(s):  
Luke Lindgren ◽  
Rafaela Simoes-torigoe ◽  
Karcher Morris ◽  
Frank E. Talke
Keyword(s):  
Electric Fields ◽  
Medical System ◽  
Metal Powders ◽  
Antimicrobial Coatings ◽  
Hospital Acquired Infections ◽  
Tract Infections ◽  
Quantum Espresso ◽  
Hospital Acquired ◽  
Actual Particle

Abstract Catheter associated urinary tract infections (CAUTIs) are an endemic problem in the American medical system, causing nearly 32% of all hospital-acquired infections (HAIs) [1]. Novel antimicrobial coatings for catheters, consisting of metal powders (Ag/Ag2O) and polydimethylsiloxane (PDMS), have recently been developed to combat this problem [2,3]. The active ingredients in these coatings were modeled using simplified assumptions in both ANSYS Maxwell and Quantum Espresso to determine the electric field strength at various particle radii. SEM/EDX analysis of the Ag/Ag2O coating was also performed to simulate the particles in ANSYS and provide comparison between idealized models and actual particle geometries.

scholarly journals Biocontrol of solid surfaces in hospitals using microbial-based wipes

2017 ◽  
Vol 89 (2) ◽  
pp. 216-222 ◽  
Author(s):  
Aysin Dural-Erem ◽  
Per Wessman ◽  
Ulrika Husmark ◽  
Vincent Nierstrasz
Keyword(s):  
Physical Properties ◽  
Hospitalized Patients ◽  
Solid Surfaces ◽  
Cross Contamination ◽  
Beneficial Bacteria ◽  
Nosocomial Pathogens ◽  
Hospital Acquired Infections ◽  
Hospital Acquired ◽  
Number Of Bacteria

Hospital-acquired infections have become a major challenge which threaten the hospitalized patients’ safety. The presence of nosocomial pathogens is generally reported in connection with solid surfaces near patient environments. These surfaces become significant sources of transmission and lead most often to the contamination and cross-contamination of nosocomial pathogens to the patients and staff. This paper investigates strategies to apply beneficial bacteria on viscose-based nonwoven wipes and the viability of these beneficial bacteria on the wipes along with characterization of the physical properties of the wipes. Major findings include that it is possible to produce dry wipes which contain an adequate number of beneficial bacteria or spores. After these wipes are wetted, they can release a certain number of bacteria from the wetted wipes. These released beneficial bacteria can inhibit pathogens by growing and colonizing on the wiped surfaces.

scholarly journals Molecular characterization of Staphylococcus epidermidis strains isolated from a teaching hospital in Shanghai, China

2009 ◽  
Vol 58 (4) ◽  
pp. 456-461 ◽  
Author(s):  
Min Li ◽  
Xing Wang ◽  
Qian Gao ◽  
Yuan Lu
Keyword(s):  
Medical Devices ◽  
Staphylococcus Epidermidis ◽  
Hospital Setting ◽  
Clonal Analysis ◽  
Hospital Environment ◽  
Hospital Acquired Infections ◽  
Hospital Acquired ◽  
Sequence Types ◽  
Seriously Ill

Staphylococcus epidermidis is a leading cause of hospital-acquired infections, mostly associated with the use of medical devices in seriously ill or immunocompromised patients. Currently, the clonal characteristics of S. epidermidis in the hospital environment in China are unknown; neither is it known why these sequence types are easily disseminated in the hospital setting. In this study, multilocus sequence typing (MLST) was employed for the clonal analysis of 80 S. epidermidis isolates collected from patients with S. epidermidis infections. MLST revealed a total of 16 different sequence types among these isolates. ST2, which contained exclusively ica-positive, IS256-positive and biofilm-forming isolates, represented the majority of clinical strains tested. Of the S. epidermidis strains circulating in the hospital environment in China, as many as 96.25 % are resistant to meticillin. Four staphylococcal chromosomal cassette mec (SCCmec) types were identified among the total 80 S. epidermidis isolates, none of the strains carried an SCCmec I cassette. All of the ST2 isolates carried the SCCmec type III cassette. Taken together, the combination of biofilm-forming ability and antibiotic resistance helps ST2 become successfully established within nosocomial environments, and promotes the device-related infection and bacteraemia.

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