scholarly journals 1208 Silent Sinus Syndrome: Systematic Literature Review and Report of Case Treated with A Customised PEEK Orbital Floor Implant

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
K A Denholm ◽  
R J J Pilkington ◽  
D J W Keith

Abstract Aim Silent sinus syndrome is a rare condition characterised by progressive, painless enophthalmos with subsequent development of hypoglobus due to orbital floor resorption. It is caused by hypoplasia of the ipsilateral maxillary sinus due to atelectasis. It may be associated with previous orbital floor surgery or trauma or may be idiopathic. We describe the case of a 33-year-old female treated with a customised orbital floor implant, and a review of the condition from available literature. Method A total of 53 patients with a diagnosis of silent sinus syndrome reported in 7 different papers from 2003-2020 were compared in age, presenting signs and symptoms, radiographic findings and the types of treatment provided. Results The patients ranged from ages 19 to 91, with an average age of 45.1 years, and a male to female split of 29:24. The most common presenting sign was progressive unilateral enophthalmos, usually in the absence of any ocular symptoms. Treatments included endoscopic maxillary antroscopy, orbital floor repair (prefabricated or customised) and septoplasty. Conclusions Silent sinus syndrome typically presents with unilateral enophthalmos which is often painless and not associated with any visual disturbance. It possesses characteristic clinical and radiographic signs. The management of choice is surgical and does not tend to recur in the years immediately following resolving treatment. Since the advent of 3D printing, accurate customised orbital plates can now be designed to correct the hypoglobus which is a major aesthetic component when it presents in this condition.

2014 ◽  
Vol 67 (suppl. 1) ◽  
pp. 65-68
Author(s):  
Ljiljana Jovancevic ◽  
Slobodan Savovic ◽  
Slavica Sotirovic-Senicar ◽  
Maja Buljcik-Cupic

Introduction. Silent sinus syndrome is a rare condition, characterized by spontaneous and progressive enophthalmos and hypoglobus associated with atelectasis of the maxillary sinus and downward displacement of the orbital floor. Patients with this syndrome present with ophthalmological complaints, without any nasal or sinus symptoms. Silent sinus syndrome has a painless course and slow development. It seems to be a consequence of maxillary sinus hypoventilation due to obstruction of the ostiomeatal unit. The CT scan findings are typical and definitely confirm the diagnosis of silent sinus syndrome. Case report. We present the case of a 35-year-old woman, with no history of orbital trauma or surgery. She had slight righthemifacial pressure with no sinonasal symptoms. The patient had no double vision nor other ophthalmological symptoms. The diagnosis of silent sinus syndrome was based on the gradual onset of enophthalmos and hypoglobus, in the absence of orbital trauma (including surgery) or prior symptoms of sinus disease. On paranasal CT scans there was a complete opacification and atelectasis of the right maxillary sinus with downward bowing of the orbital floor. The patient was treated with functional endoscopic sinus surgery, with no orbital repair. Conclusion. Silent sinus syndrome presents with orbithopaties but is in fact a rhinologic disease, so all ophthalmologists, rhinologists and radiologists should know about it. The treatment of choice for silent sinus syndrome is functional endoscopic sinus surgery, which should be performed with extra care, by an experienced rhinosurgeon.


2018 ◽  
Vol 7 (4) ◽  
pp. 1-5
Author(s):  
Aleksandra Sobolewska ◽  
Pedro Clarós

Spontaneous, painless enophthalmos, hypoglobus with orbital floor resorption and maxillary sinus collapse on the ipsilateral side is recognised as a rare condition known as the silent sinus syndrome. This paper aimed to present an unusual association of natural childbirth and the onset of orbital floor displacement caused by silent sinus syndrome. We wanted to present a case of a 31-year-old woman presented with a 3-month history of painless, progressive right enophthalmos otherwise utterly asymptomatic who developed symptoms shortly after natural childbirth. That association have never been presented before in literature. We also wanted to discuss the pregnancy-related nasal congestion. We present our experience with these case treated with a single-stage procedure, focusing on the advantages of this one-step approach.


2013 ◽  
Vol 2 (2) ◽  
pp. 69-73 ◽  
Author(s):  
Victoria Wilson

Aim This systematic literature review was performed to establish a definition of peri-implantitis, what makes a patient more susceptible to peri-implantitis, the signs and symptoms of peri-implantitis (including radiographic findings), treatment options for peri-implantitis, and to investigate what constitutes a suitable oral hygiene regime. Method A systematic literature review and analysis of publications included in PubMed (articles published between 1998 and 2003; English language; search terms “peri-implantitis”; “mucositis”; “partially edentulous”; “preventative maintenance”; “peri-implantitis and plaque control”; “tissue augmentation”; “diet maintenance of peri-implantitis”; “oral hygiene instruction for implants”) was performed to identify papers providing information about peri-implantitis. Separately sourced publications with peri-implantitis related titles and abstracts were reviewed and analysed. The set criteria for inclusion were peer-reviewed articles. Of 53 papers identified, 23 were included for systematic review. Results Analysis of the papers revealed that patients with implants are more susceptible to developing peri-implantitis than are patients with natural teeth to developing periodontal disease. This is due to the varied peri-implant tissue that surrounds the implant in comparison with the tissue that surrounds a natural tooth. If active periodontal disease is present, peri-implantitis may also develop; however, other secondary factors may also need to be present for this to occur. Conclusion A comprehensive periodontal examination should be carried out prior to implant surgery. The patient should be informed of the necessity of regular maintenance following implant surgery and the prerequisite of maintaining a comprehensive oral hygiene regime to avoid peri-implantitis.


Author(s):  
Stephanie Christensen ◽  
Peter J. Tebben ◽  
David Sas ◽  
Ana L. Creo

Introduction: Hereditary Hypophosphatemic Rickets with Hypercalciuria (HHRH) is a rare condition of renal phosphate wasting due to SLC34A3 mutations [1]. Patients exhibit low serum phosphorus, high 1,25-dihydroxyvitamin D and inappropriately high urine phosphate and calcium. However, symptoms vary and little is known about specific phenotype-genotype correlations. Methods: We report three HHRH cases in unrelated 12-year-old, 9-year-old and 14-year-old patients and perform a systematic literature review. Results: All three patients exhibited labs typical of HHRH. Yet, their presentations differed and 2 novel SLC34A3 variants were identified. As found in the literature review, bone symptoms are most common (50%), followed by renal symptoms (17%), combined bone and renal symptoms (18%) and asymptomatic (9%). Conclusion: These three cases highlight the variability of presenting signs and symptoms among individuals with HHRH. An accurate diagnosis is critical, as treatment differs from other disorders of phosphate wasting, urinary stones, and mineralization defects.


2021 ◽  
Vol 49 (2) ◽  
pp. 030006052199223
Author(s):  
Xiaolin Zhang ◽  
Hongmei Jiao ◽  
Xinmin Liu

Esophageal diverticulum with secondary bronchoesophageal fistula is a rare clinical entity that manifests as respiratory infections, coughing during eating or drinking, hemoptysis, and sometimes fatal complications. In the present study, we describe a case of bronchoesophageal fistula emanating from esophageal diverticulum in a 45-year-old man who presented with bronchiectasis. We summarize the characteristics of this rare condition based on a review of the relevant literature.


2021 ◽  
pp. 194589242198916
Author(s):  
Henry D. Zheng ◽  
Jeffrey C. Mecham ◽  
Yassmeen Abdel-Aty ◽  
Devyani Lal ◽  
Michael J. Marino

Background The histopathology and microbiology associated with silent sinus syndrome (SSS) have not been well described. Objective This study details the histopathological and microbiological characteristics in addition to radiographic findings of SSS in comparison to those of chronic maxillary sinusitis (CRS). Methods 42 patients diagnosed with SSS at Mayo Clinic Hospital in Arizona were identified. Paranasal computed tomography scans of the 42 SSS patients as well as 42 matched CRS patients were analyzed in order to assess differences in the prevalence of septal spurs/deviation. 20 of the SSS patients and 19 of the matched CRS patients also had histopathology and microbiology reports, which were compiled and summarized. Additionally, 19 SSS and 19 matched CRS patients were contacted via phone survey for a more complete patient history regarding maxillary dental disease/surgery. Results SSS patients have a significantly higher prevalence of septal spurs/deviation than CRS patients. The microbiomes of SSS patients more closely resemble those of healthy controls than those of CRS patients. Analysis of the histopathology of SSS reveals chronic, non-specific inflammation similar to that seen in non-eosinophilic CRS without polyps. SSS patients were significantly more likely to have a history of maxillary dental disease requiring surgery. Conclusion These data support the hypothesis that the pathogenesis of SSS is more likely due to anatomical/mechanical factors than inflammatory/microbiological factors.


2018 ◽  
Vol 07 (05) ◽  
pp. 419-423 ◽  
Author(s):  
Rishabh Jethanandani ◽  
Schneider Rancy ◽  
Keith Corpus ◽  
Jeffrey Yao ◽  
Scott Wolfe

Background Isolated capitate nonunion is rare. No consensus on the appropriate treatment for this condition exists. Case Description We reported two cases of capitate fracture nonunion presenting several months after untreated high-impact wrist trauma. Treatment was delayed as both patients' nonunions were missed on conventional radiographs. Both were ultimately diagnosed with advanced imaging and successfully treated with internal fixation and autogenous bone grafting. The relevant literature pertaining to capitate nonunion was reviewed. Literature Review Immobilization and internal fixation with bone grafting for capitate nonunion have been described in the literature. Loss of vascular supply and progression to avascular necrosis is a concern after capitate nonunion. Clinical Relevance We present two cases and review the literature on the diagnosis and treatment of this rare injury to guide management. Internal fixation with autogenous bone grafting could play a role in management for this rare condition.


BMJ Open ◽  
2017 ◽  
Vol 7 (11) ◽  
pp. e015594 ◽  
Author(s):  
James Mahon ◽  
Carlos Lifschitz ◽  
Thomas Ludwig ◽  
Nikhil Thapar ◽  
Julie Glanville ◽  
...  

ObjectivesTo estimate the cost of functional gastrointestinal disorders (FGIDs) and related signs and symptoms in infants to the third party payer and to parents.Study designTo estimate the cost of illness (COI) of infant FGIDs, a two-stage process was applied: a systematic literature review and a COI calculation. As no pertinent papers were found in the systematic literature review, a ‘de novo’ analysis was performed. For the latter, the potential costs for the third party payer (the National Health Service (NHS) in England) and for parents/carers for the treatment of FGIDs in infants were calculated, by using publicly available data. In constructing the calculation, estimates and assumptions (where necessary) were chosen to provide a lower bound (minimum) of the potential overall cost. In doing so, the interpretation of the calculation is that the true COI can be no lower than that estimated.ResultsOur calculation estimated that the total costs of treating FGIDs in infants in England were at least £72.3 million per year in 2014/2015 of which £49.1 million was NHS expenditure on prescriptions, community care and hospital treatment. Parents incurred £23.2 million in costs through purchase of over the counter remedies.ConclusionsThe total cost presented here is likely to be a significant underestimate as only lower bound estimates were used where applicable, and for example, costs of alternative therapies, inpatient treatments or diagnostic tests, and time off work by parents could not be adequately estimated and were omitted from the calculation. The number and kind of prescribed products and products sold over the counter to treat FGIDs suggest that there are gaps between treatment guidelines, which emphasise parental reassurance and nutritional advice, and their implementation.


2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi198-vi198
Author(s):  
Ruchi Raval ◽  
Aadi Pandya ◽  
Jaspreet Behl ◽  
Sumul Raval

Abstract PURPOSE As more information is gathered about brain metastases, it still remains that the current prognosis of brain metastases is very poor. Due to this, it is imperative that physicians are aware of the most important components regarding brain metastases. This literature review will encompass the most current literature in order to highlight the most crucial information. METHODS All mentioned studies and literature reviews cited in the paper were obtained through various sites, and were published between 1996 and 2017. The main components that were required from the papers reviewed included where in the body the brain metastases originated from, where in the brain they tended to spread to, what the signs and symptoms typical of patients with brain metastases are, and what the options are in terms of treatment. RESULTS Using the results from a variety of studies performed within the past three decades, it is apparent that brain metastases most commonly originate from, in order of increasing frequency, lung cancer, breast cancer, melanoma, and colorectal cancer. In addition, it is reaffirmed that the magnetic resonance imaging (MRI) is the best diagnostic tool to be used when dealing with brain metastases. The most frequent signs and symptoms of a brain metastases include cognitive changes, headaches, weakness, and seizures. Finally, supportive treatment includes use of corticosteroids, antiepileptic drugs (AEDs), and anticoagulation therapy. Definitive treatment for brain metastases varies based on size, location, and prevalence in the brain, but the most effective options include chemotherapy, radiation therapy, and surgery. CONCLUSIONS The study’s results confirm the need for more research to be done regarding brain metastases, and better options to increase the survival of patients.


2021 ◽  
Vol 26 (9) ◽  
pp. 452-457
Author(s):  
Paula Boyer

Chronic obstructive pulmonary disease (COPD) is being increasingly diagnosed in the UKs on the rise, and is expected to continue to rise due to an ageing population with multiple co-morbidities and exposure to risk factors, such as cigarette smoke, noxious gases and air pollutants. The prevalence of this disease is high is areas of socioeconomic deprivation and among high industrial areas. The use of self-management plans in COPD is recommended by the National Institute for Health and Care Excellence (NICE), to enable to patients with this disease to be competent and confident in taking part in managing their own health condition and recognising signs and symptoms of an exacerbation. The aim of this article is to discuss self-management of COPD and the clinical guidance surrounding exacerbation of disease. A follow-up literature review will focus on the effectiveness of self-management plans in COPD.


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