scholarly journals Phytosterols Deficiency in a Diet of Young People: Results of the Nutritional Assessment

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 338-338
Author(s):  
Aleksei Korolev ◽  
Elena Fanda ◽  
Elena Nikitenko ◽  
Elena Denisova ◽  
Ekaterina Kirpichenkova ◽  
...  

Abstract Objectives Phytosterols are important biologically active components of the human diet, preventing dyslipidemia, and atherosclerosis and reduce the risk of developing metabolic syndrome and cardiovascular pathologies. This study was designed with two aims: (a) To assess the level of phytosterols intake; (b) To describe which food sources make the largest contribution to phytosterols intake. Methods The level of consumed phytosterols and their main food sources were assessed using the 24-hour recall method using the database the national Institute of health and social security of Finland (Fineli). A survey was conducted among 125 students aged 17 to 29 years. The average age of students was 22.38 ± 1.73 years, and included 94 females and 31 males. Results None of the respondents reached the recommended phytosterols level (300 mg/day), although 97.6% of them included various sources of phytosterols in a diet. Only for 8.8% of participants intake of phytosterols was more than half the recommended level (153.54–249.96 mg/day). The main sources of phytosterols in this group were: onions – 72.7% of respondents included it's in their diet, sunflower oil and fresh tomatoes – 63.6%, potatoes – 54.5%, fresh cucumbers – 45.4%, apples and white cabbage 36.3%, tomato paste 27.2%, cauliflower, Chinese cabbage, parsley, beets – 18.8%, corn and olive oils, sauerkraut, broccoli, Brussels sprouts, beans, avocado, kiwi – 9.09%. For 88.8% of participants, dietary phytosterols intake was less than half the recommended level (2.13–146.39 mg/day). In this group, the main sources of phytosterols were: sunflower oil – 52.5%, potatoes – 46.8%, onions – 43.2%, fresh tomatoes – 36.9%, fresh cucumbers – 34.2%, fresh apples – 29.7%, bananas – 20.7%, white cabbage and sauerkraut – 17.1%, sweet red pepper – 13.5%, fresh and canned peas – 11.7%, parsley and dill – 10.8%, Chinese cabbage, beets and olive oil – 8.1%, oranges, green onions and beans – 5.4%. The students did not include phytosterols-rich foods in their diet: green grapes, black and red currants, blueberries, cranberries, and raspberries. Conclusions Obviously, in order to achieve the optimal level of phytosterols in the diet, it is not enough to use their sources with low and medium phytosterols content. It is necessary to include in the diet either foods enriched with them, or selectively foods with their high content. Funding Sources No funding.

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Aleksei Korolev ◽  
Ekaterina Kirpichenkova ◽  
Elena Nikitenko ◽  
Elena Denisova

Abstract Objectives Lutein and zeaxanthin are non-vitamin carotenoids, which located in macula. These carotenoids reduce the risk of progression of age-related macular degeneration. The purpose of research to analyze the amount of lutein and zeaxanthin in diets of young health people and to asses food choices rich non-vitamin carotenoids. Methods Adults aged 20–25 y (n = 424, 113 males age 22.0 ± 0.9 y, 311 females age 22.0 ± 0.8 y). Lutein and zeaxanthin levels from food sources have been estimated using the 24-hour recall method. The questionnaire was designed specifically to conduct a specific study. It provided for the selection of food sources, and indication of the consumed amount of lutein and zeaxanthin. Results Of the 424 students only 24 (5.7%) have reached the recommended level (8.84 ± 3.39 mg/day). The main sources of lutein and zeaxanthin in this group were zucchini (29.2%); broccoli, lettuce, persimmon and spinach (12.5% each), pumpkin and parsley (8.3% each), peas (4.2%). The dietary intake of non-vitamin carotenoids for 41 students (9,7%) was 50.0–99.9% (4.19 ± 0.76 mg/day) of the recommended level. The student's diet of this group included sources of lutein and zeaxanthin such as lettuce (34.2%), broccoli (24.4%), zucchini (12.2%), corn and persimmon (7.3% each), pumpkin and spinach (4.9% each), orange juice and peas (2.4% each). Most of the study participants (306 students – 72.1%) had insufficient intake of lutein and zeaxanthin with food sources and was less than half of the recommended level (0.93 ± 0.82 mg/day). The major sources of non-vitamin carotenoids were eggs (22.9%); red raw tomatoes (15.0%); lettuce (11.1%); zucchini (7.2%); fast food products and orange juice (5.6% each); peas (4.9%); carrot (4.2%); ketchup (3.9%); parsley (3.6%); corn and persimmon (3.3% each); broccoli (2.3%); kiwi (1.6%); pumpkin (1.3%); basil, green onion, canned fish, celery, canned red tomatoes, tomato juice, pistachios and spinach (0.3–0.9%). Sources of lutein and zeaxanthin, such as Brussels sprouts, blackberries, blueberries, were not included in the diet. Moreover, 53 (12,5%) students had no sources of lutein and zeaxanthin in their diet. Conclusions For the most of students, the recommended intake of lutein and zeaxanthin was not achieved. The major food sources were included in the diet in insufficient quantities. Funding Sources No funding.


Author(s):  
I. A. Kyazimova ◽  
А. А. Kasumova ◽  
А. А. Nabiev

Production of plant products, including juices around the world increases continuously. In the fruit and vegetable juices contain a significant amount of monosaccharides (glucose and fructose), organic acids, vitamins, phenolic compounds, mineral substances and other biologically active components that determine the nutritional and dietary value. For the prevention of various diseases associated with impaired metabolic processes, we developed a new technology of preparation of food by blending juice of pumpkin, quince and persimmon. Thus prepared organic blended juice contains a substantial amount of free glucose and fructose, different phenolic compounds, a sufficient amount of organic acids, mineral elements, including iodine and other components that determine its nutritional and biological value. In prepared juices were evaluated the quantitative indicators of β-carotene, vitamin C, glucose and fructose, sucrose, starch, pectin substances. Also in the atomic absorbtion spectrometer Analyst 400 (PerkinElmer, USA) was analyzed content of the organic acids and phenolic compounds. Prepared juices were tested in accordance with 10 point scoring scale. It is established that all juices contain a sufficient amount of the minerals. In pumpkin and quince juices not contain iodine while it presents in sufficient amount in persimmon juice that’s why in the blended juice mineral in addition to mineral elements iodine are contained. In pumpkin and persimmon aliphatic acids are contained in small amount. For this reason during the blending process was used quince juice which is rich in aliphatic acids. The blended juice is light straw color, with delicious flavor, a slight astringent property and a balanced taste.


Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 1022
Author(s):  
Dragana Arsenijevic ◽  
Bojana Stojanovic ◽  
Jelena Milovanovic ◽  
Aleksandar Arsenijevic ◽  
Milos Simic ◽  
...  

The main biologically active components of plants belonging to the genus Allium, responsible for their biological activities, including anti-inflammatory, antioxidant and immunomodulatory, are organosulfur compounds. The aim of this study was to synthetize the mixture of dipropyl polysulfides (DPPS) and to test their biological activity in acute hepatitis. C57BL/6 mice were administered orally with DPPS 6 h before intravenous injection of Concanavalin A (ConA). Liver inflammation, necrosis and hepatocytes apoptosis were determined by histological analyses. Cytokines in liver tissue were determined by ELISA, expression of adhesive molecules and enzymes by RT PCR, while liver mononuclear cells were analyzed by flow cytometry. DPPS pretreatment significantly attenuated liver inflammation and injury, as evidenced by biochemical and histopathological observations. In DPPS-pretreated mice, messenger RNA levels of adhesion molecules and NADPH oxidase complex were significantly reduced, while the expression of SOD enzymes was enhanced. DPPS pretreatment decreased protein level of inflammatory cytokines and increased percentage of T regulatory cells in the livers of ConA mice. DPPS showed hepatoprotective effects in ConA-induced hepatitis, characterized by attenuation of inflammation and affection of Th17/Treg balance in favor of T regulatory cells and implicating potential therapeutic usage of DPPS mixture in inflammatory liver diseases.


1975 ◽  
Vol 16 (1) ◽  
pp. 11-24 ◽  
Author(s):  
Thomas J. Meyer ◽  
Edgar Ribi ◽  
Ichiro Azuma

2021 ◽  
Vol 37 (5) ◽  
pp. 88-95
Author(s):  
N.A. Petrov ◽  
S.N. Zorin ◽  
N.A. Biryulina ◽  
V.K. Mazo

Abstract- One of the promising food sources of biologically active substances is quinoa grain, which is valued for its high content of protein, sulfur-containing amino acids, lysine, fiber, and minerals. In addition, quinoa grain can be a valuable food source of polyphenolic compounds and phytoecdysteroids. The method for production of a concentrate of flavonoids and 20-hydroxyecdysone from quinoa grains sorbed on coagulated egg protein has been developed. The in vivo evaluation of efficacy of the developed food ingredient was conducted using male Wistar rats under immobilization stress and after exhausting physical exertion. The consumption of the food ingredient prevented an increase in the level of the main stress markers, catecholamines, in animals subjected to immobilization stress. The opposite effect was observed in animals that received the food ingredient after exhausting physical exertion: their levels of catecholamines were significantly higher than in the rest comparison groups. Using the Elevated Plus Maze and Open Field tests, it was shown that the consumption of the developed concentrate neutralized the negative effect of immobilization stress and treadmill exercise on anxiety in Wistar rats. The results obtained require additional study under conditions of preventive introduction of the food ingredient into the diet of intact animals, as well as a toxicological safety assessment. Key words: quinoa, 20-hydroxyecdysone, flavonoids, stress, immobilization, exhaustive physical exercise, catecholamines, corticosterone This work was supported by the Russian Scientific Foundation, grant no. 19-16-00107.


1975 ◽  
Vol 21 (12) ◽  
pp. 2019-2027
Author(s):  
M. Laguerre ◽  
R. Turcotte

The tuberculin activity of protoplasmic extracts isolated from living BCG was purified successively by gel filtration on Sephadex G-100 and G-75, and by electrophoresis on 7.5% and on gradient (6–18%) polyacrylamide gels. The tuberculin-active fractions, as determined in BCG-sensitized guinea pigs, were used as the starting material for each of the following fractionation steps.The physicochemical properties and the antigenic activity of the biologically active fractions have shown that a single component, or only a few ones with similar properties, possessed high tuberculin activity. These active components were proteins having relatively high molecular weights (about 72 000) and could behave as antigens.


Author(s):  
Biswaranjan Ray ◽  
Santosh Kumar Mahapatra ◽  
Pradipta Kumar Behera ◽  
Ashok K Panigrahi

Objective: As per the ethnopharmacological information has Butea monosperma been used to treat diabetes mellitus by the tribal people of tropical and subtropical areas. However, there is no much more scientific report available about the antidiabetic property of the leaves of the plant. Hence, the study was undertaken to evaluate the antidiabetic effect of ethanolic extract of B. monosperma on blood levels of adrenaline-induced and glucose feed diabetic rabbits.Methods: The three different doses of the extracts (100, 200, and 400 mg/kg) were administered orally to an experimental animal. The animals were induced diabetics by adrenaline and high glucose diet. Blood glucose level was measured accordingly. For antidiabetic activity, photocolorimeter was used to monitoring the blood glucose level with crest kit box (GOP-POD method).Results: The extracts showed considerable dose-dependent activity. However, the dose 400 mg/kg showed considerable lower of blood glucose level. p<0.01 indicates the significance result. 8 hrs reading 182.5±3.83 for 400 mg does is most effective for reducing blood sugar.Conclusion: The study indicates that the ethanolic extract of B. monosperma leaves possesses antidiabetic properties which suggest the presence of biologically active components.


Biomeditsina ◽  
2019 ◽  
pp. 34-45
Author(s):  
V. N. Karkischenko ◽  
M. S. Dulya ◽  
R. A. Ageldinov ◽  
S. L. Lyublinskiy ◽  
N. N. Karkischenko

For the first time, a liposomal form of a new original drug based on the Siberian musk deer preputial gland extract was obtained and characterized. An effective and scalable method of high-pressure homogenization was used for preparative extraction of liposomes from musk extracts. For the obtained liposomal product, such indicators as the quality of size distribution, homogeneity and the degree of inclusion of biologically active components were characterized using the methods of dynamic light scattering, transmission microscopy, preparative and analytical chromatography and chromatography-mass spectrometry. A homogeneous dispersion of musk liposomes with a uniform size distribution was obtained, with the maximum distribution values being achieved at 50 and 240 nm. The ζ-potential of the obtained nanoparticles of –35...–47 mV confirmed a high physicochemical stability of the developed liposomal dispersion. According to the gel filtration chromatography and mass spectrometry results, the degree of inclusion of the target musk extract components in the liposomes was 55–75% in terms of steroid and total protein values. The obtained quality indicators indicate that the developed liposomal composition of musk deer extracts can be used as a high-effective natural adaptogen.


Food Research ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 322-329
Author(s):  
F. Yeasmin ◽  
N.N. Hira ◽  
H. Rahman ◽  
M.N. Islam

The perishable herb ginger (Zingiber officinale) possesses natural aroma and different biologically active components which are beneficial for our health. This can be dried for preservation in pick season for shelf-life increment. This study studied the analysis of the chemical composition, moisture sorption isotherm, dehydration kinetics of ginger for preservation. Air drying was carried out using a cabinet dryer at different temperatures and thickness. According to the sorption isotherm study, monolayer moisture content (MMC) is higher as per Guggenheim-Anderson-DeBoer (GAB) equation compared to the Brunauer-Emmett-Teller (BET) equation. Drying rate increased with the increase in temperature at constant thickness while the adverse result was found with the increase in thickness at a constant temperature. Then, powder-based drinks were prepared by using five different percentages of ginger. The preferences of consumers were measured by statistical analysis of the scores obtained from the response of organoleptic taste panel. The sample containing 1.84% ginger powder was considered the best in overall acceptability


Author(s):  
Maksim Gurin ◽  
◽  
Aleksey Venediktov ◽  
Yuliya Glumskova ◽  
Kristina Korneeva ◽  
...  

Damage to the tendon-ligamentous apparatus places serious limitations on a personʼs physical activity. Injuries are especially common in physically healthy people leading an active lifestyle, such as athletes. To treat such injuries in orthopaedics and traumatology, autoplastic operations are performed or prostheses made of synthetic or biological materials are installed. The known treatment methods, in spite of their effectiveness, have a number of serious drawbacks, which often limit their use. Therefore, the search for new approaches and materials for plastic ligaments is an urgent task. Today, biotissue prostheses are accumulating advantages over their synthetic counterparts. The most promising raw material for biological ligament prostheses, due to its availability in the required quantity and optimal size, is the flexor and extensor calf tendons. This paper aimed to develop a method for treating xenogenic tendon to manufacture ligament prostheses and assessing its biocompatibility in a heterotopic implantation model. To manufacture a ligament prosthesis, the raw material was subjected to mechanical cleaning and chemical-physical treatment, as well as treatment with supercritical carbon dioxide fluid with the addition of the nonionic surfactant Tween 80, which together contributed to effective decellularization and removal of other biologically active components, while maintaining the physical and mechanical parameters and natural fiberarchitectonics of native raw materials. The biocompatible properties of ligament prosthesis specimens made from the flexor and extensor calf tendons using this method were evaluated in a model of heterotopic implantation into the subcutaneous adipose tissue of rats. The results obtained confirm the promising use of this material, treated according to the proposed method, in clinical practice.


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