Atrial fibrillation burden: an update—the need for a CHA2DS2-VASc-AFBurden score
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Abstract Atrial fibrillation (AF) is an established independent risk factor for stroke. Current guidelines regard AF as binary; either present or absent, with the decision for anti-coagulation driven by clinical variables alone. However, there are increasing data to support a biological gradient of AF burden and stroke risk, both in clinical and non-clinical AF phenotypes. As such, this raises the concept of combining AF burden assessment with a clinical risk score to refine and individualize the assessment of stroke risk in AF—the CHA2DS2VASc-AFBurden score. We review the published data supporting a biological gradient to try and construct a putative schema of risk attributable to AF burden.
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2014 ◽
Vol 111
(03)
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pp. 385-391
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2018 ◽
Vol 118
(12)
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pp. 2162-2170
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