scholarly journals Association between obesity and life courses in young adulthood. Results from the KiGGS cohort study

2021 ◽  
Vol 31 (Supplement_3) ◽  
Author(s):  
P Rattay ◽  
A Schienkiewitz ◽  
F Vogelgesang
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
Young Adulthood ◽  
Single Parent ◽  
Parental Home ◽  
Related Individual ◽  
Early Parenthood ◽  
Life Courses ◽  
Education And Employment

Abstract   In the last decades, young adulthood has established as an independent phase of life with important biographical transitions impacting further life course and health. In turn, health in adolescence can also affect the transitions into young adulthood. So far, for Germany there are no analyses on the association between family-related and employment-related biographies and obesity in young adults. The analysis is based on data from the KiGGS cohort study on 3,100 participants aged 23-31 at second follow-up (t2). Using BMI measurements at t0 (2003-2006) and at t2 (2014-2017), obesity groups were formed (no obesity, incidence, remission, persistence). Sequence analysis was used to retrospectively determine family-related and education/employment-related individual trajectories. Differences in life courses between obesity groups were calculated using discrepancy tests. Young adults with incident obesity were more likely to have children or to be a single parent than young adults without obesity at t2. Young adults with obesity at t0 lived longer in the parental home than those without obesity. Young adults with incident or persistent obesity were less likely to attend university and had experienced longer periods of unemployment than those without obesity at t0 and t2. The employment sequences of those without obesity at t2 were not statistically different. Both family and employment biographies were associated with obesity trajectories in young people. However, based on the analysis, it cannot be clarified whether early parenthood led to obesity or early transitions into parenthood led to interruptions in education or employment and subsequently to obesity. The finding that young adults with obesity were less likely to attend university and more likely to be unemployed could be related to disadvantages or discrimination in school, education or work. Obesity in adolescence that did not persist into young adulthood had less adverse effects on education and employment. Key messages Young people’s obesity trajectories were linked to different family/employment biographies. The life courses of young adults with obesity were more often marked by early parenthood and unemployment.

scholarly journals Associations with kidney transplant survival and eGFR decline in children and young adults in the United Kingdom: a retrospective cohort study

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Alexander J. Hamilton ◽  
Lucy A. Plumb ◽  
Anna Casula ◽  
Manish D. Sinha
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
Young Adulthood ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Graft Loss ◽  
Glomerular Diseases ◽  
Children And Young Adults ◽  
Egfr Decline

Abstract Background Although young adulthood is associated with transplant loss, many studies do not examine eGFR decline. We aimed to establish clinical risk factors to identify where early intervention might prevent subsequent adverse transplant outcomes. Methods Retrospective cohort study using UK Renal Registry and UK Transplant Registry data, including patients aged < 30 years transplanted 1998–2014. Associations with death-censored graft failure were investigated with multivariable Cox proportional hazards. Multivariable linear regression was used to establish associations with eGFR slope gradients calculated over the last 5 years of observation per individual. Results The cohort (n = 5121, of whom n = 371 received another transplant) was 61% male, 80% White and 36% had structural disease. Live donation occurred in 48%. There were 1371 graft failures and 145 deaths with a functioning graft over a 39,541-year risk period. Median follow-up was 7 years. Fifteen-year graft survival was 60.2% (95% CI 58.1, 62.3). Risk associations observed in both graft loss and eGFR decline analyses included female sex, glomerular diseases, Black ethnicity and young adulthood (15–19-year and 20–24-year age groups, compared to 25–29 years). A higher initial eGFR was associated with less risk of graft loss but faster eGFR decline. For each additional 10 mL/min/1.73m2 initial eGFR, the hazard ratio for graft loss was 0.82 (95% CI 0.79, 0.86), p < 0.0001. However, compared to < 60 mL/min/1.73m2, higher initial eGFR was associated with faster eGFR decline (> 90 mL/min/1.73m2; − 3.55 mL/min/1.73m2/year (95% CI -4.37, − 2.72), p < 0.0001). Conclusions In conclusion, young adulthood is a key risk factor for transplant loss and eGFR decline for UK children and young adults. This study has an extended follow-up period and confirms common risk associations for graft loss and eGFR decline, including female sex, Black ethnicity and glomerular diseases. A higher initial eGFR was associated with less risk of graft loss but faster rate of eGFR decline. Identification of children at risk of faster rate of eGFR decline may enable early intervention to prolong graft survival.

scholarly journals Early Predictors of Trajectories of Tobacco Use Level from Adolescence to Young Adulthood: A 16-Year Follow-Up of the TEMPO Cohort Study (1999–2015)

2018 ◽  
Vol 25 (1) ◽  
pp. 2-9
Author(s):  
Virgile Clergue-Duval ◽  
Murielle Mary-Krause ◽  
Camille Bolze ◽  
Eric Fombonne ◽  
Maria Melchior
Keyword(s):  
Cohort Study ◽  
Young Adulthood ◽  
Tobacco Use ◽  
Early Predictors

Maternal Partner Criminality and Cannabis use in Young Adulthood: Prospective Study

2007 ◽  
Vol 41 (6) ◽  
pp. 546-553 ◽  
Author(s):  
Mohammad R. Hayatbakhsh ◽  
Stuart A. Kinner ◽  
Konrad Jamrozik ◽  
Jake M. Najman ◽  
Abdullah A. Mamun
Keyword(s):  
Young Adults ◽  
Young Adulthood ◽  
Early Adulthood ◽  
Cannabis Use ◽  
Birth Cohort Study ◽  
Mater Hospital ◽  
Frequent Use ◽  
Increased Risk ◽  
History Of

Objectives: The present study examined whether the experience of the arrest or incarceration of a mother's partner before a child reached 14 years of age was associated with use of cannabis in early adulthood and, if so, whether this association was confounded or mediated by other factors. Method: Data were from the Mater Hospital University of Queensland Study of Pregnancy, a prospective birth cohort study in Brisbane, Australia. The history of partner arrest and incarceration was reported by mothers at the 14 year follow up. Mothers were divided into four groups: mothers whose partner had no history of arrest or incarceration, mothers reporting partner arrest, mothers reporting partner incarceration, and unpartnered mothers. Young adults’ cannabis use was assessed at 21 years. Other covariates were prospectively measured between birth and 14 years. Results: After controlling for potential confounding and mediating factors, frequent use of cannabis at age 21 was more likely among young adults with a history of maternal partner arrest (odds ratio=2.3; 95% confidence interval: 1.4–3.8). There was no significant association between maternal partner incarceration or single motherhood, and cannabis use at age 21. Conclusions: Arrest of the mother's partner before the child is 14 is associated with that child's increased cannabis use at age 21 but this does not appear to be the case for children whose fathers have been imprisoned. It appears that for children whose fathers have been arrested, the father's ongoing presence in the family may result in worse outcomes for the child, including an increased risk of cannabis use in young adulthood.

scholarly journals Effect of Montelukast 10 mg in Elderly Patients with Mild and Moderate Asthma Compared with Young Adults. Results of a Cohort Study

2018 ◽  
Vol 12 (1) ◽  
pp. 67-74
Author(s):  
Guillermo Sánchez ◽  
Diana Buitrago
Keyword(s):  
Older Adults ◽  
Young Adults ◽  
Cohort Study ◽  
Elderly Patients ◽  
Inhaled Corticosteroids ◽  
Age Groups ◽  
The Elderly ◽  
Moderate Asthma ◽  
Beta 2

Background: The clinical characteristics and physio-pathogenic mechanisms of asthma in patients older than 60 years appear to differ from the behavior described for other age groups. Therefore, the effectiveness of medications for elderly patients with asthma should not be extrapolated from studies conducted on teenagers or young adults. Objective: The study aimed to establish the clinical effect of montelukast 10 mg in elderly patients with mild and moderate asthma compared to its effect on young adults. Method: A prospective cohort study was conducted during 12 weeks of follow-up, which consecutively included the total population of adult patients attended by a group of 21 general practitioners, between July and December 2016. Young adults (18-59 years) and older adults were included (60 years or older) with mild or moderate asthma, which, according to the criteria of his treating physician, had been prescribed montelukast 10 mg/day. The variables of interest were: use of inhaled corticosteroids during the last month, use of inhaled beta-2 adrenergic agonists as a rescue in the last month, having attended the emergency service during the last month due to an asthma attack, presence of wheezing in the physical examination, the number of attacks in the last month and the number of days without symptoms in the last month. Results: A total of 126 patients entered the cohort and 104 completed the follow-up, of which 29% were older adults. On admission, 65.4% of patients (68/104) had used rescue inhaled beta2 in the last month and had been using schemes with corticosteroids. After 12 weeks of follow-up, 58.1% (43/74) of the young adults required treatment schedules with corticosteroids, while in the elderly, only 36.7% of the patients (11/30) required this treatment scheme (p-value: 0.047). Regarding the use of rescue inhaled beta-2 at 12 weeks, 55% of young adults reported using them, compared to 33.3% of older adults (p-value: 0.041). Conclusion: In this cohort of patients, treated with montelukast 10 mg/day for 12 weeks, there was a reduction of broncho-obstructive symptoms and exacerbations of the disease. In older adults compared to young adults, a greater reduction in the use of beta2 agonists rescue medications and in the concomitant use of inhaled corticosteroid schemes was documented.

scholarly journals Shared meals among young adults are associated with better diet quality and predicted by family meal patterns during adolescence

2012 ◽  
Vol 16 (5) ◽  
pp. 883-893 ◽  
Author(s):  
Nicole Larson ◽  
Jayne Fulkerson ◽  
Mary Story ◽  
Dianne Neumark-Sztainer
Keyword(s):  
Young Adults ◽  
Young Adulthood ◽  
Sociodemographic Factors ◽  
Population Based ◽  
Household Composition ◽  
Family Meals ◽  
Meal Patterns ◽  
Food And Beverage ◽  
Shared Meals

AbstractObjectiveTo describe shared meal patterns and examine associations with dietary intake among young adults.DesignPopulation-based, longitudinal cohort study (Project EAT: Eating and Activity in Teens and Young Adults).SettingParticipants completed surveys and FFQ in high-school classrooms in Minneapolis/St. Paul, MN, USA in 1998–1999 (mean age = 15·0 years, ‘adolescence’) and follow-up measures online or by mail in 2008–2009 (mean age = 25·3 years, ‘young adulthood’).SubjectsThere were 2052 participants who responded to the 10-year follow-up survey and reported on frequency of having shared meals.ResultsAmong young adults, the frequency of shared meals during the past week was as follows: never (9·9 %), one or two times (24·7 %), three to six times (39·1 %) and seven or more times (26·3 %). Having more frequent family meals during adolescence predicted a higher frequency of shared meals in young adulthood above and beyond other relevant sociodemographic factors such as household composition and parental status. Compared with young adults who never had family meals during adolescence, those young adults who reported seven or more family meals per week during adolescence had an average of one additional shared meal per week. Having more frequent shared meals in young adulthood was associated with greater intake of fruit among males and females, and with higher intakes of vegetables, milk products and some key nutrients among females.ConclusionsNutrition professionals should encourage families of adolescents to share meals often and establish the tradition of eating together, and work with young adults to ensure that healthy food and beverage choices are offered at mealtimes.

scholarly journals Mortality in a cohort of 3.1 million children, adolescents and young adults

2020 ◽  
Vol 74 (3) ◽  
pp. 260-268 ◽  
Author(s):  
Joel G Ray ◽  
Astrid Guttmann ◽  
Jose Silveira ◽  
Alison L Park
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
Urban Areas ◽  
Demographic Variables ◽  
Adolescents And Young Adults ◽  
First Year ◽  
Preventive Strategies ◽  
Self Harm ◽  
First Year Of Life

BackgroundMany youth deaths occur in the first year of life, from prematurity and anomalies. Detailing mortality after age 1 year may differentially guide preventive strategies in children, adolescents and young adults.MethodsA cohort study in Ontario, Canada comprised 3 139 698 children born from 1990 to 2016. Adjusted HR (aHR) for death between 1 and 24 years were generated, comparing demographic variables and parity.ResultsAfter a median of 13.7 years of follow-up, 6930 deaths occurred between ages 1 and 24 years (incidence rate 17.0 per 100 000 person-years), peaking at age 23 years (43.7 per 100 000). The aHR for death was higher among males than females (1.44, 95% CI 1.37 to 1.51), rural versus urban areas (1.48, 95% CI 1.39 to 1.58), lowest versus highest income areas (1.39, 95% CI 1.29 to 1.51) and at parity 1 (1.16, 95% CI 1.10 to 1.23), parity 2 (1.34, 95% CI 1.23 to 1.45), parity 3+ (1.96, 95% CI 1.74 to 2.21), each relative to a child without an older sibling. Among males, the proportion of deaths due to injury jumped from 30% before age 15 years to 65% thereafter, and in females, from 28% to 51%. Intentional self-harm/assault explained 11% of injury-related deaths among males before age 15 years, and 20% thereafter, with respective figures of 18% and 17% for females. Deaths outside of hospital increased with age, from 35% at age 1 year, to 66% at age 22 years.ConclusionThere is a heightened susceptibility of dying starting at age 15 years, especially among males, from injury, and arising outside of hospital.

Abstract P107: Serum Urate Trajectories in Young Adulthood and Incident Cardiovascular Disease Events By Middle Age; The Coronary Artery Risk Development in Young Adults (cardia) Study

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Nagisa Morikawa ◽  
Michael P. Bancks ◽  
Yuichiro Yano ◽  
Masanori Kuwabara ◽  
Angelo L. Gaffo ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Young Adults ◽  
Young Adulthood ◽  
Clinical Characteristics ◽  
Middle Age ◽  
Serum Urate ◽  
Hazard Ratios ◽  
Study Participants ◽  
Incident Cardiovascular Disease

Introduction: Higher levels of serum urate (UA) obtained on a single occasion have been shown to be associated with a higher risk of cardiovascular disease (CVD) events among middle-aged or older adults. However, little is known regarding UA trajectory patterns during young adulthood and their associations with CVD outcomes by middle age. Hypothesis: We hypothesize that higher UA trajectory is associated with a higher risk for CVD events compared to lower UA trajectories. Methods: We included data from 4845 CARDIA Study participants (mean age at the Year 20 exam 44.8±3.7 (37-55) years; 50.8% African American; 55.6% female). Sex-specific UA trajectories were assessed using group-based trajectory modeling (PROC TRAJ in SAS version 9.4) based on UA levels obtained at baseline (Year 0) and 10, 15, 20 years later. Covariates included age, sex, race, and clinical characteristics at Year 20 (body mass index, diabetes and creatinine). We estimated hazard ratios (HR) for CVD events (coronary heart disease, heart failure, and stroke) from Year 20 (2005-06) through 2017. Results: We identified 3 UA trajectories in men and 3 similar but lower UA trajectories in women, characterized by low-increasing (men: 30%; n=652, mean UA 5.1; women 43%, n=1191, mean UA 3.9), moderate-increasing (men: 52%; n=1290, mean UA 6.4; women 45%, n=1284, mean UA 5.0), and high-increasing UA (men: 17%; n=377, mean UA 8.0; women 12%, n=305, mean UA 6.4) (Figure 1). Sex-specific trajectories were pooled. Over a median follow-up of 10.9 years, 203 incident CVD events occurred. The adjusted HRs for CVD events were 0.98 (95%CI, 0.66-1.45) for the pooled moderate-increasing group and 1.77 (95%CI, 1.10-2.84) for the pooled high-increasing group compared to the pooled low-increasing group. Conclusions: High-increasing UA trajectory during young adulthood was associated with an greater risk of CVD events by middle age. Modeling UA trajectories may help identify young adults at higher risk for CVD events.

scholarly journals Influence of Childhood Asthma and Allergies on Occupational Exposure in Early Adulthood: A Prospective Cohort Study

2019 ◽  
Vol 16 (12) ◽  
pp. 2163 ◽  
Author(s):  
Orianne Dumas ◽  
Nicole Le Moual ◽  
Adrian J. Lowe ◽  
Caroline J. Lodge ◽  
Jan-Paul Zock ◽  
...  
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
High Risk ◽  
Occupational Exposure ◽  
Parental Education ◽  
Early Adulthood ◽  
Allergic Diseases ◽  
Hay Fever ◽  
History Of

We aimed to determine whether history of asthma/allergies in childhood was associated with avoidance of jobs with exposure to asthmagens in early adulthood. The Melbourne Atopic Cohort Study recruited 620 children at high risk of allergic diseases at birth (1990–1994). Asthma, hay fever and eczema were evaluated by questionnaires during childhood. A follow-up in early adulthood (mean age: 18 years) collected information on the current job. Occupational exposure to asthmagens/irritants was evaluated using a job-exposure matrix. The association between history of asthma/allergies in childhood and working in a job with exposure to asthmagens/irritants was evaluated by logistic regression, adjusted for age, sex and parental education. Among 363 participants followed-up until early adulthood, 17% worked in a job with exposure to asthmagens/irritants. History of asthma (35%) was not associated with working in an exposed job (adjusted OR: 1.16, 95% CI: 0.65–2.09). Subjects with history of hay fever (37%) and eczema (40%) were more likely to enter exposed jobs (significant for hay fever: 1.78, 1.00–3.17; but not eczema: 1.62, 0.91–2.87). In conclusion, young adults with history of allergies were more likely to enter exposed jobs, suggesting no avoidance of potentially hazardous exposures. Improved counselling against high risk jobs may be needed for young adults with these conditions.

scholarly journals Locus of Control and Negative Cognitive Styles in Adolescence as Risk Factors for Depression Onset in Young Adulthood: Findings From a Prospective Birth Cohort Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Ilaria Costantini ◽  
Alex S. F. Kwong ◽  
Daniel Smith ◽  
Melanie Lewcock ◽  
Deborah A. Lawlor ◽  
...  
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
Locus Of Control ◽  
Young Adulthood ◽  
Cognitive Styles ◽  
Birth Cohort Study ◽  
Confounding Factors ◽  
External Locus ◽  
External Locus Of Control ◽  
Probable Depression

Whilst previous observational studies have linked negative thought processes such as an external locus of control and holding negative cognitive styles with depression, the directionality of these associations and the potential role that these factors play in the transition to adulthood and parenthood has not yet been investigated. This study examined the association between locus of control and negative cognitive styles in adolescence and probable depression in young adulthood and whether parenthood moderated these associations. Using a UK prospective population-based birth cohort study: the Avon Longitudinal Study of Parents and Children (ALSPAC), we examined the association between external locus of control and negative cognitive styles in adolescence with odds of depression in 4,301 young adults using logistic regression models unadjusted and adjusted for potential confounding factors. Interaction terms were employed to examine whether parenthood (i.e., having become a parent or not) moderated these associations. Over 20% of young adults in our sample were at or above the clinical threshold indicating probable depression. For each standard deviation (SD) increase in external locus of control in adolescence, there was a 19% (95% CI: 8–32%) higher odds of having probable depression in young adulthood, after adjusting for various confounding factors including baseline mood and different demographic and life events variables. Similarly, for each SD increase in negative cognitive styles in adolescence, there was a 29% (95% CI: 16–44%) higher odds of having probable depression in the adjusted model. We found little evidence that parenthood status moderated the relationship between external locus of control or negative cognitive styles in adolescence and probable depression following adjustment for confounding factors. Effect estimates were comparable when performed in the complete case dataset. These findings suggest that having an external locus of control and holding negative cognitive styles in mid- to late adolescence is associated with an increased likelihood of probable depression in young adulthood.

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