The Combined Effect of Lower Extremity Function and Cognitive Performance on Perceived Walking Ability Among Older People: A 2-Year Follow-up Study

Background The use of large‐bore (LB) arterial access and guiding catheters has been advocated for complex percutaneous coronary intervention. However, the impact of LB transradial access (TRA) and transfemoral access (TFA) on extremity dysfunction is currently unknown. Methods and Results The predefined substudy of the COLOR (Complex Large‐Bore Radial PCI) trial aimed to assess upper and lower‐extremity dysfunction after LB radial and femoral access. Upper‐extremity function was assessed in LB TRA‐treated patients by the Quick Disabilities of the Arm, Shoulder, and Hand questionnaire and lower‐extremity function in LB TFA‐treated patients by the Lower Extremity Functional Scale questionnaire. Extremity pain and effect of access site complications and risk factors on extremity dysfunction was also analyzed. There were 343 patients who completed analyzable questionnaires. Overall, upper and lower‐extremity function did not decrease over time when LB TRA and TFA were used for complex percutaneous coronary intervention, as represented by the median Quick Disabilities of the Arm, Shoulder, and Hand score (6.8 at baseline and 2.1 at follow‐up, higher is worse) and Lower Extremity Functional Scale score (56 at baseline and 58 at follow‐up, lower is worse). Clinically relevant extremity dysfunction occurred in 6% after TRA and 9% after TFA. A trend for more pronounced upper‐limb dysfunction was present in female patients after LB TRA ( P =0.05). Lower‐extremity pain at discharge was significantly higher in patients with femoral access site complications ( P =0.02). Conclusions Following LB TRA and TFA, self‐reported upper and lower‐limb function did not decrease over time in the majority of patients. Clinically relevant limb dysfunction occurs in a small minority of patients regardless of radial or femoral access. Registration URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03846752.

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Frailty, walking ability and self-rated health in predicting institutionalization: an 18-year follow-up study among Finnish community-dwelling older people

Aging Clinical and Experimental Research ◽

10.1007/s40520-020-01551-x ◽

2020 ◽

Author(s):

Anna Viljanen ◽

Marika Salminen ◽

Kerttu Irjala ◽

Päivi Korhonen ◽

Maarit Wuorela ◽

...

Keyword(s):

Older People ◽

Community Dwelling ◽

Walking Ability ◽

Self Rated Health ◽

Follow Up Study ◽

Community Dwelling Older People

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Catatonia is associated with worse cognitive performance in patients with first-episode psychosis antipsychotic-naive: a 3-month follow-up study

10.26226/morressier.5971be84d462b80290b5267b ◽

2017 ◽

Author(s):

Jorge Cuevas Esteban

Keyword(s):

Cognitive Performance ◽

First Episode Psychosis ◽

First Episode ◽

Follow Up Study ◽

Episode Psychosis

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Mediating effects of lower extremity function on the relationship between night sleep duration and cardiovascular disease risk: a cross-sectional study in elderly Chinese without cardiovascular diseases

BMJ Open ◽

10.1136/bmjopen-2020-046015 ◽

2021 ◽

Vol 11 (7) ◽

pp. e046015

Author(s):

Hui Zhang ◽

Xiaoyu Chen ◽

Peipei Han ◽

Weibo Ma ◽

Yuanyuan Zhang ◽

...

Keyword(s):

Lower Extremity ◽

Sleep Duration ◽

Physical Performance ◽

Indirect Effect ◽

Night Sleep ◽

Lower Extremity Function ◽

Cvd Risk ◽

Extremity Function ◽

Elderly Chinese ◽

The Relationship

ObjectiveThe purpose of this study is to investigate the mediating effect of physical performance on the relationship between night sleep duration and risk of cardiovascular disease (CVD) in elderly Chinese without CVD.Methods782 participants without CVD over 65 years (average: 70.82±3.86 years, 448 women) were included in this study. CVD risk was calculated by the Framingham Risk Score and participants were divided into four groups of night sleep duration (in hours): <7 hours, ≥7–8 hours, >8–9 hours and >9 hours. Upper extremity function was measured by grip strength and lower extremity function was measured by the Short Physical Performance Battery (SPPB), consisting of balance, 4 m walk and chair stands tests.ResultsAfter adjusting for covariates, long night sleep duration (>9 hours) and CVD risk were significantly positively associated compared with moderate night sleep duration (≥7–8 hours) (β=1.152; 95% CI 0.05 to 2.25). SPPB total score (indirect effect ab=−0.122; 95% CI −0.291 to –0.0008) rather than grip strength partially mediated the relationship between long night sleep duration and CVD risk, in which chair stands played a major mediating role (indirect effect ab=−0.171; 95% CI −0.040 to –0.0006), while balance (indirect effect ab=−0.016; 95% CI −0.100 to 0.063) and 4 m walk (indirect effect ab=0.048; 95% CI −0.066 to 0.201) did not.ConclusionsLower extremity function, especially lower limb muscle strength, partially mediates a positive association between long night sleep duration and CVD risk in the elderly without CVD. Suitable interventions for physical performance and sleep may minimise the risk of subsequent CVD.

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The Impact of a Ten Week Training Program on Lower- Extremity Function and Fear of Falling

Proceedings of the Human Factors and Ergonomics Society Annual Meeting ◽

10.1177/1071181397041002145 ◽

1997 ◽

Vol 41 (2) ◽

pp. 1369-1369

Author(s):

Darryl G. Humphrey ◽

Laszlo Stumpfhauser

Keyword(s):

Lower Extremity ◽

Training Program ◽

Fear Of Falling ◽

Lower Extremity Function ◽

Extremity Function ◽

The Impact

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Diabetes and Nontraumatic Lower Extremity Amputations: Incidence, risk factors, and prevention--a 12-year follow-up study in Nauru

Diabetes Care ◽

10.2337/diacare.19.7.710 ◽

1996 ◽

Vol 19 (7) ◽

pp. 710-714 ◽

Cited By ~ 63

Author(s):

A. R. G. Humphrey ◽

G. K. Dowse ◽

K. Thoma ◽

P. Z. Zimmet

Keyword(s):

Risk Factors ◽

Lower Extremity ◽

Follow Up Study ◽

Incidence Risk

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Work Ability and Employment in Rheumatoid Arthritis: A Cross-Sectional Study on the Role of Muscle Strength and Lower Extremity Function

International Journal of Rheumatology ◽

10.1155/2018/3756207 ◽

2018 ◽

Vol 2018 ◽

pp. 1-11 ◽

Cited By ~ 3

Author(s):

Carolin Berner ◽

Sandra Haider ◽

Igor Grabovac ◽

Thomas Lamprecht ◽

Karl Heinrich Fenzl ◽

...

Keyword(s):

Muscle Strength ◽

Lower Extremity ◽

Work Ability ◽

Employment Status ◽

Knee Extensor ◽

Lower Extremity Function ◽

Cross Sectional ◽

Hand Grip ◽

Extremity Function ◽

Knee Extensor Strength

Objective. The aim of the present study was to assess the association between muscle strength, lower extremity function, employment status, and work ability in RA patients. Methods. One hundred seropositive RA outpatients of working age were included in this cross-sectional study. Employment status was assessed by interview and work ability by the Work Ability Index-Single Item Scale (WAS). Muscle strength was determined using dynamometer measurement of isometric hand grip and knee extensor strength. Lower extremity function was measured using the short physical performance battery (SPPB). Regression models estimate the association between unemployment, work ability and muscle strength, and lower extremity function, controlling for sociodemographic and disease-related factors. Results. Forty-one percent of the RA patients were not gainfully employed, and their median work ability had a good WAS value (7.00 [4.00-7.00]). Patients with better knee extensor strength (OR=1.07, 95% CI [1.02-1.12) and better physical performance (OR=1.71, 95% CI [1.18-2.49]) had a significantly better chance of gainful employment. The odds for hand grip strength remained significant when adjusted for sociodemographic (OR=1.5, 95% CI [1.00-1.09]), but not for disease-specific variables. Better hand grip strength (β=0.25, p=0.039) and better knee extensor strength (β=0.45, p=0.001) as well as better lower extremity function (SPPB) (β=0.51, p<0.001) remained significantly associated with work ability following adjustment for sociodemographic and disease-specific variables. Conclusions. The association of employment status and work ability with parameters of physical fitness suggests that improvement in muscle strength and lower extremity function may positively influence work ability and employment in individuals with RA.

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