Evaluation of Glutaraldehyde and Hydrogen Peroxide for Sanitizing Packaging Materials of Medical Devices in Sterility Testing

1982 ◽  
Vol 65 (5) ◽  
pp. 1155-1161
Author(s):  
Samuel Eskenazi ◽  
Olga E Bychkowski ◽  
Marilyn Smith ◽  
James D Macmillan

Abstract External surfaces of packaging materials used for sterile medical devices may introduce contaminants into working areas used for sterility testing. Light wiping with tissues moistened with alkaline 2% glutaraldehyde (Cidex) or 3% hydrogen peroxide effectively reduced counts on 5 X 8 cm strips of packaging material (Tyvek) inoculated with 107 spores of Bacillus subtilis. The ability of antimicrobial agents to penetrate packaging material and kill contaminants on the medical device was tested by inoculating filter membranes with ca 100 cells of Pseudomonas aeruginosa or Staphylococcus aureus or ca 100 spores of Bacillus subtilis. A sterile square of test packaging material placed over the inoculated membrane (direct method) or 0.5 cm above the membrane (indirect method) was wiped with the antimicrobial agent. Except for polyethylene film (3 mil), all materials tested, including glassine and several types of coated and uncoated Tyvek, were penetrated by the agents, killing cells on the inoculated membranes. Death rates varied, depending on the organism, packaging material, and testing method. It is suggested that penetration tests be performed before using antimicrobial agents for sanitizing packaging materials during sterility tests.

2012 ◽  
Vol 5 (2) ◽  
pp. 225-231
Author(s):  
Hana Smítková ◽  
Miroslav Marek ◽  
Jaroslav Dobiáš

Abstract In this study the surface adjustment by two polymers with addition of preservatives of chosen packaging material on starch base with incorporated additives has been investigated. Its bioactive function was verified by measuring zones of inhibition and mutual comparison of bacteriocin released from samples coated with polymers. The best results were achieved when chosen sample containing 15 % of sawdust, 5 % of PVOH and 2 % of calcium stearate was coated by 30 % of Kombilak L1917 solution or 10 % copolyamide 6/12 solution. The addition of antimicrobial agents slightly increased hydrophilicity of coated samples. Immobilization of preservative had no significant effect on the mechanical strength of coated samples. For both types of relevant polymers used amount of immobilized Nisaplin was quite sufficient for effective inhibition of microbial cultures Lactobacillus Helveticus CH1.


1980 ◽  
Vol 43 (7) ◽  
pp. 528-529
Author(s):  
STANLEY E. WALLEN ◽  
HOMER W. WALKER

The purpose of this work was to determine if the resistance of bacterial spores could be increased by subculturing spores that had survived exposure to hydrogen peroxide. Spores surviving exposure to 5% hydrogen peroxide held at 50 C were subcultured, allowed to sporulate and subsequently exposed to hydrogen peroxide as before. After 10 generations of subculturing, the resistance of the spores had not increased. It is concluded that, in food processes in which high concentrations of hydrogen peroxide are used to sterilize food processing equipment and food packaging materials, the development of a resistant spore population is unlikely.


Author(s):  
M. V. Lukyanenko ◽  
E. P. Viktorova ◽  
A. D. Achmiz ◽  
S. O. Semenikhin

In the production of quality food products, special attention must be paid to its packaging and storage. These process steps are especially important for products containing labile biologically active substances. In order to select packaging materials and packing method, an analysis of the scientific literature was conducted with the search query “packaging materials for foodstuffs” and “the effect of packaging on the preservation of vitamins during food storage” in the Google Scholar system. The article presents trends in the development and use of packaging materials, reflects the advantages and disadvantages of biopolymers, as well as prospects for improving the characteristics of packaging materials. As an example, for the choice of packaging material and packing method, data from Russian scientists based on packaging materials used in the Russian Federation is given. Storage of beef steaks in bags with reduced gas permeability under vacuum and a modified gas atmosphere with a reduced content of free space for 14 days contributes to the inhibition of bacteria. Storage of sterilized and ultra-pasteurized milk is preferably in bags of a three-word film filled with titanium dioxide, in comparison with glass packaging, due to a decrease in light transmission and a decrease in the rate of decomposition of vitamin C. It is preferable to store orange juice in packages of combined materials that exclude the presence of an air cushion, which positively affects the content of vitamin C. Based on the analysis of packaging materials used in the food industry and taking into account the humidity and chemical composition of the vitamin and mineral concentrate, it seems appropriate to use packaging materials made of polymer films with high light and gas impermeability, which can reduce the rate of destruction of vitamin C and other easily oxidized components and eliminate the use of ? -radiation, replacing it by evacuation. The use of edible films for vitamin and mineral concentrate as packaging materials remains open and requires more careful study.


Author(s):  
Shreya Shah ◽  
Fatema Matkawala ◽  
Sarika Garg ◽  
Sadhana Nighojkar ◽  
Anand Nighojkar ◽  
...  

Bio-plastics are either bio-based polymers or capable of degradation into simple compounds. The rising development in the production and use of bio-plastics has globally revolutionized the dependency on traditional plastics. The conventional plastics prepared from petroleum, coal and natural gas have been extensively used by humans since antiquity as a prime component of almost all the materials used in day to day life. Since, these plastics are non-biodegradable; they cause serious impact on the environment. Recent years have witnessed the introduction of a wide variety of bio-plastics derived from natural polymers such as starch, cellulose, chitin etc. These bio-plastics are now being utilised in packaging materials, electronics, medical devices; holding immense potential for utility in future. This mini-review confers about types of bio-plastics, their utility in different sectors and their future prospective.


Author(s):  
Eleonora Bottani ◽  
Roberto Montanari ◽  
Giuseppe Vignali ◽  
Luigi Guerra

This paper presents the outcomes of a comprehensive and detailed analysis of the Italian food market, targeting the Fast Moving Consumer Goods products and aimed at defining the existing relationships between product characteristics and packaging technologies. A sample of 175 products has been examined, and the corresponding characteristics and packaging technologies were derived from an in-field investigation performed in large and small Italian retailers. Subsequent statistical analyses were first focused on providing descriptive statistics concerning the packaging materials used for food products. Then, cluster analysis was exploited to group products on the basis of the material used for the primary packaging. Discriminant analysis was also adopted to identify product characteristics that significantly contribute to the choice of packaging material. Finally, based on the clusters obtained, contingency tables were used to explore possible relationships among packaging material, packaging techniques and relevant product characteristics. Results of this study could provide useful guidelines to food manufacturers to identify the most suitable packaging technology for new food products.


Polymers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 2588
Author(s):  
Mansuri M. Tosif ◽  
Agnieszka Najda ◽  
Aarti Bains ◽  
Grażyna Zawiślak ◽  
Grzegorz Maj ◽  
...  

In recent years, scientists have focused on research to replace petroleum-based components plastics, in an eco-friendly and cost-effective manner, with plant-derived biopolymers offering suitable mechanical properties. Moreover, due to high environmental pollution, global warming, and the foreseen shortage of oil supplies, the quest for the formulation of biobased, non-toxic, biocompatible, and biodegradable polymer films is still emerging. Several biopolymers from varied natural resources such as starch, cellulose, gums, agar, milk, cereal, and legume proteins have been used as eco-friendly packaging materials for the substitute of non-biodegradable petroleum-based plastic-based packaging materials. Among all biopolymers, starch is an edible carbohydrate complex, composed of a linear polymer, amylose, and amylopectin. They have usually been considered as a favorite choice of material for food packaging applications due to their excellent forming ability, low cost, and environmental compatibility. Although the film prepared from bio-polymer materials improves the shelf life of commodities by protecting them against interior and exterior factors, suitable barrier properties are impossible to attain with single polymeric packaging material. Therefore, the properties of edible films can be modified based on the hydrophobic–hydrophilic qualities of biomolecules. Certain chemical modifications of starch have been performed; however, the chemical residues may impart toxicity in the food commodity. Therefore, in such cases, several plant-derived polymeric combinations could be used as an effective binary blend of the polymer to improve the mechanical and barrier properties of packaging film. Recently, scientists have shown their great interest in underutilized plant-derived mucilage to synthesize biodegradable packaging material with desirable properties. Mucilage has a great potential to produce a stable polymeric network that confines starch granules that delay the release of amylose, improving the mechanical property of films. Therefore, the proposed review article is emphasized on the utilization of a blend of source and plant-derived mucilage for the synthesis of biodegradable packaging film. Herein, the synthesis process, characterization, mechanical properties, functional properties, and application of starch and mucilage-based film are discussed in detail.


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