scholarly journals 133 Effects of methionine source and zinc level on growth performance of nursery pigs

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 106-106
Author(s):  
Henrique S Cemin ◽  
Luke A Swalla ◽  
Sharlie A Hansen ◽  
Jamie L Pietig ◽  
Stewart T Galloway ◽  
...  
Keyword(s):  
Growth Performance ◽  
Experimental Period ◽  
Zinc Level ◽  
Interactive Effects ◽  
Nursery Pigs ◽  
Improved Performance ◽  
D 20 ◽  
Treatment Structure ◽  
Main Effects ◽  
Organic Source

Abstract A 44-d experiment was conducted to evaluate the effects of Met source and Zn level on growth performance of nursery pigs. Treatments were arranged in a 2 × 2 factorial treatment structure with main effects of Met source (DL-Met or MHA-Ca) and added Zn level (100 or 3,000 mg/kg). A total of 1,008 pigs (PIC 337 × Camborough), initially 5.6 kg, were used, with 9 replicates per treatment. The basal Zn level of 100 mg/kg was from organic source, while the added level of 2,900 mg/kg was from Zn oxide. The different added Zn levels were fed from d 0 to 20, whereas the different Met sources were fed throughout the experimental period (d 0 to 44). Pigs were weighed and feed disappearance measured to calculate ADG, ADFI, and G:F. Data were analyzed with SAS MIXED procedure. There was no evidence (P > 0.10) for Met × Zn interactive effects. From d 0 to 20, pigs fed DL-Met had a tendency (P < 0.10) for higher ADG and BW. Pigs fed 3,000 mg/kg added Zn had higher (P < 0.05) ADFI, ADG, and BW. From d 20 to 44, there was no evidence for differences (P > 0.10) between Met source. Pigs previously fed 100 mg/kg added Zn had improved (P < 0.05) ADFI and ADG. Overall (d 0 to 44), pigs fed DL-Met had a tendency (P < 0.10) for higher ADG and final BW. No evidence for differences (P > 0.10) was observed between pigs fed 100 or 3,000 mg/kg added Zn. In conclusion, pigs fed DL-Met tended to have improved performance. Feeding 3,000 mg/kg added Zn improved performance until d 20, but no differences were observed in the overall nursery period.

scholarly journals PSIV-17 Effects of zinc level and calcium source on growth performance of nursery pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 177-178
Author(s):  
Henrique S Cemin ◽  
Luke A Swalla ◽  
Jamie L Pietig ◽  
Sharlie A Hansen ◽  
Ernie L Hansen
Keyword(s):  
Growth Performance ◽  
Zinc Level ◽  
Nursery Pigs ◽  
Calcium Source ◽  
The Common ◽  
Main Effects ◽  
Organic Source

Abstract An experiment was conducted to determine the effects of Zn level and Ca source on nursery performance. Treatments were arranged in a 2 × 2 factorial with main effects of added Zn (100 or 3,000 mg/kg) and Ca source (limestone or Ca citrate). The basal level of Zn (100 mg/kg) was from organic source, whereas the 3,000 mg/kg was created with the inclusion of 2,900 mg/kg Zn oxide. A total of 3,701 pigs (PIC 337 × Camborough), initially 5.4 kg, were used with 18 replicates per treatment. Experimental diets were fed for 19 d, followed by a common diet from d 19 to 49. Pigs were weighed and feed disappearance measured to calculate ADG, ADFI, and G:F. Data were analyzed with SAS MIXED procedure. There were interactions (P < 0.05) between Zn and Ca for G:F from d 10 to 19 and 0 to 19. From d 10 to 19, feeding 3,000 mg/kg added Zn improved G:F with both Ca sources, but the magnitude of improvement was greater when diets contained Ca citrate. From d 0 to 19, only pigs fed Ca citrate presented improvement in G:F when fed 3,000 mg/kg added Zn. For main effects, feeding 3,000 mg/kg added Zn improved (P < 0.05) ADG and G:F from d 0 to 10. From d 10 to 19 and 0 to 19, feeding 3,000 mg/kg added Zn increased (P < 0.05) ADG and ADFI. During the common period (d 19 to 49), pigs previously fed 100 mg/kg added Zn had improved (P < 0.01) G:F. Overall (d 0 to 49), no differences (P > 0.10) in performance were observed. In conclusion, there were no major differences in performance between Ca sources. Pigs fed 3,000 mg/kg added Zn presented improved growth performance from d 10 to 19 but not overall.

scholarly journals 244 Effect of Fiber Source and Crude Protein Level on Nursery Pig Performance

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 94-95
Author(s):  
Kelsey Hammers ◽  
Hilda I Calderon ◽  
Mike D Tokach ◽  
Jason C Woodworth ◽  
Robert D Goodband ◽  
...  
Keyword(s):  
Growth Performance ◽  
Crude Protein ◽  
Phase 1 ◽  
Experimental Period ◽  
Oat Hulls ◽  
Nursery Pigs ◽  
Nursery Pig ◽  
Pig Performance ◽  
Two Phases ◽  
Main Effects

Abstract A total of 360 pigs (DNA 200′400, initially 5.0 kg) were used in a 45-d growth trial to determine the effects of fiber source and crude protein (CP) level in diets without pharmacological levels of ZnO on nursery pig growth performance and fecal dry matter (DM). Pigs were randomly assigned to 1 of 8 treatments with 5 pigs/pen and 9 pens/treatment. Treatments were arranged in a 2×4 factorial with main effects of CP (21 or 18%) and fiber source [none, coarse wheat bran (CWB), oat hulls, or cellulose (Arbocel, J. Rettenmaier USA, Schoolcraft, MI)]. Fiber source was added to equalize the level of insoluble fiber contributed from 4% CWB, resulting in the addition of 1.85% oat hulls or 1.55% cellulose. Diets were fed in two phases (d 0 to 10 and 10 to 24) followed by a common diet (d 24 to 45). The 21% CP diets contained 1.40% SID Lys in phase 1 and 1.35% SID Lys in phase 2. Treatment diets were formulated to a maximum SID Lys:digestible CP level of 6.35%, thus SID Lys decreased in the 18% CP (1.25% SID Lys) diets. Data were analyzed using the lmer function in R. No fiber source × CP level interactions (P >0.05) were observed. Decreasing dietary CP decreased (P = 0.05) ADG, G:F, and d 24 BW. Overall, ADG and d 45 BW decreased (P < 0.05) for pigs fed 18% CP diets. No main effects of fiber source were observed for growth performance throughout the study. Fecal DM increased (P < 0.05) for pigs fed added cellulose compared to pigs fed no fiber or CWB in the experimental period. In conclusion, reducing dietary CP decreased growth performance and the inclusion of cellulose improved fecal DM of nursery pigs.

scholarly journals PSIX-13 Effects of zinc and copper levels on growth performance of nursery pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 179-180
Author(s):  
Henrique S Cemin ◽  
Luke A Swalla ◽  
Jamie L Pietig ◽  
Sharlie A Hansen ◽  
Ernie L Hansen
Keyword(s):  
Growth Performance ◽  
Soybean Meal ◽  
Whey Permeate ◽  
Nursery Pigs ◽  
Overall Performance ◽  
Treatment Structure ◽  
Main Effects

Abstract A 20-d experiment was conducted to evaluate the effects of added Zn and Cu on growth performance of nursery pigs. Treatments were arranged in a 2 × 2 factorial treatment structure with main effects of added Zn (100 or 3,000 mg/kg of diet) and Cu (10 or 200 mg/kg of diet). Basal Zn and Cu levels (100 and 10 mg/kg, respectively) were from organic sources, while the added high levels (2,900 and 190 mg/kg, respectively) were from Zn oxide and Cu hydroxychloride. A total of 784 pigs (PIC 337 × Camborough), initially 6.0 kg, were used with 7 replicates per treatment. Experimental diets were corn, soybean meal, and whey permeate-based and contained 1.38% SID Lys. Pigs were weighed and feed disappearance measured to calculate ADG, ADFI, and G:F. Data were analyzed with SAS MIXED procedure. From d 0 to 10, there was no evidence (P > 0.10) for interactive or main effects of Zn or Cu. From d 10 to 20 and overall (d 0 to 20), there was an interaction (P < 0.05) between Zn and Cu for G:F. From d 10 to 20, pigs fed 10 mg/kg added Cu had improved G:F when 3,000 mg/kg added Zn was fed; however, pigs fed 200 mg/kg added Cu had similar G:F regardless of added Zn level. There was no evidence (P > 0.10) for interaction for ADG or ADFI, indicating an additive Zn and Cu effect. Feeding 3,000 mg/kg added Zn or 200 mg/kg added Cu improved ADG, ADFI, and final BW with the highest performance observed when feeding both 3,000 mg/kg added Zn and 200 mg/kg added Cu. In summary, feeding high levels of Zn or Cu did not impact the first 10-d postweaning performance, but Zn and Cu effects were observed in the subsequent 10-d and overall performance.

scholarly journals 263 Effects of soybean meal level on growth performance of 11- to 25-kg nursery pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 87-88
Author(s):  
Henrique S Cemin ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Growth Performance ◽  
Soybean Meal ◽  
Random Effect ◽  
Fixed Effect ◽  
Nursery Pigs ◽  
Energy Value ◽  
Caloric Efficiency ◽  
Main Effects

Abstract Four experiments were conducted to determine the effects of increasing soybean meal (SBM) in diets with or without 25% DDGS on growth performance of nursery pigs. Treatments were arranged in a 2 × 3 factorial with main effects of SBM (27.5, 32.5, or 37.5%) and DDGS (0 or 25%). A total of 296, 2,502, 4,118, and 711 pigs, initially 10.6, 11.7, 12.5, and 12.3 kg, were used and there were 10, 16, 13, and 12 replicates per treatment in Exp. 1, 2, 3, and 4, respectively. Experimental diets were fed for 21 d. Pigs were weighed and feed disappearance measured to calculate ADG, ADFI, G:F, and caloric efficiency (CE). Data were analyzed using the GLIMMIX procedure of SAS with block as random effect and treatment as fixed effect. The average cull rate was 0.7, 0.5, 0.2, and 0% and the mortality rate was 0.7, 0.3, 0.4, and 0% in Exp. 1 to 4, respectively. There were interactions (P ≤ 0.039) between SBM and DDGS for G:F and CE in Exp. 2 and for ADG and ADFI in Exp. 3. These were mostly driven by increasing SBM negatively affecting performance in a greater magnitude when diets contained DDGS compared to diets without DDGS. The main effects of DDGS and SBM were more consistent across experiments. Pigs fed diets with 25% DDGS had decreased (P ≤ 0.001) ADG and ADFI in all experiments as well as poorer (P ≤ 0.028) G:F and CE except for Exp. 3. Feeding increasing amounts of SBM generally did not result in any major impact in ADG, but consistently improved (linear, P ≤ 0.078) G:F and CE across experiments. The mechanism for this response is unclear but could be driven by intrinsic components of SBM or underestimating the energy value of SBM.

scholarly journals PSVI-1 Dietary protease supplementation on growth performance and post-weaning diarrhea of nursery pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 191-192
Author(s):  
Jorge Y Perez-Palencia ◽  
David A Clizer ◽  
Christian Ramirez-Camba ◽  
Ryan S Samuel ◽  
Crystal L Levesque
Keyword(s):  
Growth Performance ◽  
Phase 1 ◽  
Dietary Treatment ◽  
Experimental Period ◽  
Phase 2 ◽  
Deficient Diet ◽  
Nursery Pigs ◽  
Feeding Program ◽  
Dietary Treatments ◽  
Fecal Score

Abstract This experiment evaluated the effect of dietary protease supplementation on pig’s growth performance and post-weaning diarrhea in a 43-d trial. A total of 936 weaned pigs [21 d of age, initial BW 5.87 ± 0.31 kg] were used in a 2 × 2 factorial design (2 nutritional levels × 2 protease levels). The nutritional levels corresponded to a standard feeding program and a reduced feeding program (15% lower SID Lys) and without or with protease supplementation (0.0125% inclusion). Piglets were distributed in 36 pens with 26 pigs per pen and 9 replicates per dietary treatment. Pigs received a common Phase 1 diet and experimental diets in Phase 2, 3, and 4, (0.91, 3.4, 4.5, and 24.0 kg/pig, respectively). Phytase was included at 2,500 U in Phase 2 – 4, all diets met energy and AA:Lys requirements for nursery pigs. Feed intake and body weight were determined every 2 weeks. A pen fecal score assessment was performed at d7, 10, and 14. Performance data were analyzed using the PROC MIXED procedure and fecal score data using the PROC FREQ procedure (SAS Inst., Inc., Cary, NC). No significant interactions (P > 0.05) were observed between dietary treatments. From d15 to 43 and during overall experimental period, pigs fed standard diets had greater BW, ADG, and G:F (P < 0.05) than pigs fed deficient diets (Table 1). On d7, pigs fed deficient diet had more (X2 < 0.05) soft and watery feces, and consequently less normal feces compared to pigs fed standard diets (Figure 1). On d7, 10, and 14, pigs fed diets with protease supplementation had more (X2 < 0.05) normal feces compared to control pigs. Overall, effects of dietary protease supplementation on growth performance were not expressive under the conditions of this study but protease addition benefited intestinal health of nursery pigs.

scholarly journals Effects of soybean meal level on growth performance of 11- to 25-kg nursery pigs12

2020 ◽  
Vol 4 (2) ◽  
pp. 694-707
Author(s):  
Henrique S Cemin ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
...  
Keyword(s):  
Growth Performance ◽  
Soybean Meal ◽  
Block Design ◽  
Average Daily Gain ◽  
Random Effect ◽  
Experimental Period ◽  
Feed Ratio ◽  
Caloric Efficiency ◽  
Quadratic Effects ◽  
Main Effects

Abstract Four experiments were conducted to determine the effects of increasing soybean meal (SBM) level in diets with or without 25% distillers dried grains with solubles (DDGS) on growth performance of nursery pigs raised in university or commercial facilities. Treatments were arranged in a 2 × 3 factorial with main effects of SBM (27.5%, 32.5%, or 37.5% of the diet) and DDGS (0% or 25% of the diet). A total of 296, 2,502, 4,118, and 711 pigs with initial body weight (BW) of 10.6, 11.7, 12.5, and 12.3 kg were used in Exp. 1, 2, 3, and 4, respectively. There were 10, 16, 13, and 12 replicates per treatment in Exp. 1, 2, 3, and 4, respectively. After weaning, pigs were fed common diets for approximately 21 d. Then, pens of pigs were assigned to treatments in a randomized complete block design with BW as the blocking factor and experimental diets were fed for 21 d. Pigs were weighed and feed disappearance measured to calculate average daily gain (ADG), average daily feed intake (ADFI), gain-to-feed ratio (G:F), and caloric efficiency (CE). Data were analyzed using the GLIMMIX procedure of SAS with block as a random effect and treatment as a fixed effect. Single degree-of-freedom contrasts were constructed to test the linear and quadratic effects of increasing SBM and their interactions with DDGS. Pigs used in all experiments did not undergo major health challenges during the experimental period and due to the low number of mortality and cull events, statistical analysis was not performed on these variables. The average cull rate was 0.7%, 0.5%, 0.2%, and 0%, and the mortality rate was 0.7%, 0.3%, 0.4%, and 0% in Exp. 1–4, respectively. There were interactions (P ≤ 0.039) between SBM and DDGS for G:F and CE in Exp. 2 and for ADG and ADFI in Exp. 3. These were mostly driven by increasing SBM negatively affecting performance in a greater magnitude when diets contained DDGS compared to diets without DDGS. The main effects of DDGS and SBM were more consistently observed across experiments. Pigs fed diets with 25% DDGS had decreased (P ≤ 0.001) ADG and ADFI in all experiments, as well as poorer (P ≤ 0.028) G:F and CE except for Exp. 3. Feeding increasing amounts of SBM generally did not result in any major impact in ADG but consistently improved (linear, P ≤ 0.078) G:F and CE across experiments.

scholarly journals Adverse effects on growth performance and bone development in nursery pigs fed diets marginally deficient in phosphorus with increasing calcium to available phosphorus ratios

2020 ◽  
Vol 98 (10) ◽  
Author(s):  
Spenser L Becker ◽  
Stacie A Gould ◽  
Amy L Petry ◽  
Leah M Kellesvig ◽  
John F Patience
Keyword(s):  
Growth Performance ◽  
Mixed Model ◽  
Linear Mixed Model ◽  
Bone Development ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Feed Ratio ◽  
Available Phosphorus ◽  
Nursery Pigs ◽  
The Impact

Abstract The objective of this experiment was to evaluate the growth performance and bone mineral content (BMC) of nursery pigs in response to increasing total calcium (Ca) to available phosphorus (aP) ratios in diets containing phytase (250 FTU/kg; Natuphos E, BASF, Florham Park, NJ). A total of 480 nursery pigs (body weight (BW) = 5.7 ± 0.6 kg) with 10 pigs per pen and 7 pens per treatment (6 pens fed 2.75:1 diet) were allotted to seven treatments consisting of increasing ratios of calcium to available phosphorus (Ca:aP): 1.25, 1.50, 1.75, 2.00, 2.25, 2.50, and 2.75. From day −7 to 0, pigs were fed a common diet. They were then fed the treatment diets during two experimental phases from day 1 to 14 and 15 to 28, respectively. Available P was formulated to 0.33% and 0.27% (approximately 90% of requirement) in dietary phases 1 and 2, respectively. BW, average daily gain (ADG), average daily feed intake (ADFI), and gain-to-feed ratio (G:F) were determined. BMC of the femur was measured on day 28 on one pig per pen using dual x-ray absorptiometry. Data were analyzed as a linear mixed model using PROC MIXED (SAS, 9.3). Orthogonal polynomial contrasts were used to determine the linear and quadratic effects of increasing the Ca:aP. Over the 28-d experimental period, increasing Ca:aP resulted in a linear decrease in ADG (353, 338, 328, 304, 317, 291, and 280 g/d; P < 0.01), ADFI (539, 528, 528, 500, 533, 512, and 489 g/d; P < 0.05), and G:F (0.68, 0.66, 0.64, 0.62, 0.61, 0.59, and 0.58; P < 0.01). Increasing Ca:aP also resulted in decreased BW on days 14 and 28 (P < 0.01). The BMC of the femur decreased with increasing Ca:aP (6.2, 6.3, 5.7, 5.9, 5.5, 5.6, and 5.3 g; P < 0.05). Regression analysis explained the impact of Ca:aP as follows on ADG (ADG [g/d] = 339 − 36x; r2 = 0.81), G:F (G:F = 0.61 – 0.03x; r2 = 0.72), and BMC (BMC [g] = 6.4 – 0.27x; r2 = 0.43), where x is the Ca:aP. In conclusion, all outcomes indicated that any level of calcium above the minimum used in this experiment impaired growth performance and skeletal development. Further research using even lower levels of dietary Ca is warranted.

scholarly journals Interactive Effects of Copper Sources and a High Level of Phytase in Phosphorus-Deficient Diets on Growth Performance, Nutrient Digestibility, Tissue Mineral Concentrations, and Plasma Parameters in Nursery Pigs

2021 ◽  
Author(s):  
Ping Ren ◽  
Juxing Chen ◽  
Deana Hancock ◽  
Mercedes Vazquez-Añón
Keyword(s):  
Growth Hormone ◽  
Growth Performance ◽  
Basal Diet ◽  
Nutrient Digestibility ◽  
Interactive Effects ◽  
Plasma Parameters ◽  
Nursery Pigs ◽  
High Level ◽  
Dietary Treatments ◽  
Mineral Concentrations

AbstractThe present study investigated the interactive effects of copper sources and a high level of phytase on growth performance, nutrient digestibility, tissue mineral concentrations, and plasma parameters in nursery pigs. Weaning piglets (N = 192; 6.06 ± 0.99 kg), blocked by body weight, were randomly allotted to 1 of 4 dietary treatments, with 12 pens per treatment and 4 pigs per pen. A basal diet for each phase was formulated to meet nutrient requirements for nursery pigs with the exception that standardized total tract digestibility (STTD) P was reduced by 0.12% and Ca was adjusted to achieve Ca/STTD P = 2.15. The 4 dietary treatments were arranged in a 2 × 2 factorial design, with 2 Cu sources (125 mg/kg Cu from copper methionine hydroxy analogue chelate (Cu-MHAC) or copper sulfate (CuSO4)) and 2 phytase levels (0 or 1500 phytase units (FTU)/kg). Results showed that there was an interaction (P < 0.05) between Cu sources and phytase on ADG during days 0–41. When phytase was not present in the diets (P deficient), there was no difference between the two Cu sources in terms of ADG during days 0–41, whereas with phytase in the diets, Cu-MHAC tended to improve (P < 0.10) ADG during days 0–41 compared with CuSO4. Pigs fed Cu-MHAC had greater apparent total tract digestibility (ATTD) of neutral and acid detergent fiber and STTD of P than those fed CuSO4. Phytase increased (P < 0.05) growth performance, ATTD of Ca and P, and plasma inositol and growth hormone concentrations. In conclusion, Cu-MHAC may be more effective in improving growth rate than CuSO4 when phytase was supplemented at 1500 FTU/kg. Cu-MHAC enhanced fiber and P digestibility regardless of phytase, compared with CuSO4. Phytase addition in P-deficient diets was effective in improving growth performance, Ca and P digestibility, and plasma inositol and growth hormone concentrations.

scholarly journals Effect of supplemented microencapsulated zinc oxide and organic acids and pure botanicals on growth performance, nutrient digestibility, blood profiles, feces microflora, and zinc level of feces in weanling pigs

2019 ◽  
Vol 99 (1) ◽  
pp. 66-73 ◽  
Author(s):  
Jin Ho Cho ◽  
Shu Dong Liu ◽  
Won Yun ◽  
Kwang Sik Kim ◽  
In Ho Kim
Keyword(s):  
Zinc Oxide ◽  
Organic Acids ◽  
Growth Performance ◽  
Control Diet ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Zinc Level ◽  
Nutrient Digestibility ◽  
Feed Ratio ◽  
Weanling Pigs

A total of 125 crossbred pigs with an initial body weight (BW) of 7.66 ± 1.30 kg were randomly distributed into one of five dietary treatments. Each treatment had five replicate pens with five pigs per pen. Treatments were as followed: (1) CON, control diet; (2) zinc oxide (ZO), CON + 0.3% ZO; (3) ZOM, CON + 0.3% ZO + 0.1% microencapsulated organic acids and pure botanicals (MOP); (4) microencapsulated zinc oxide (MZO), CON + 0.03% MZO; and (5) MZOM, CON + 0.03% MZO + 0.1% MOP. The MZO group had higher (P = 0.03) final BW than ZO group and also had higher (P = 0.04, 0.01) average daily gain and gain/feed ratio compared with ZO group during days 15–34 and throughout the experimental period. The MZO and MZOM had higher (P < 0.05) apparent total tract digestibility (ATTD) of dry matter (DM) and energy than ZO. Less (P < 0.05) feces Escherichia coli shedding was observed in the ZOM and MZOM diets compared with CON; the MZO had lowered (P = 0.001) zinc level in feces than ZO and CON. In conclusion, results indicated that supplementation with 0.3% MZO could improve the growth performance and ATTD of DM; inclusion of 0.1% MOP could decrease feces E. coli shedding and also decrease the zinc level in feces in weanling pigs.

scholarly journals Effects of dietary chlortetracycline, Origanum essential oil, and pharmacological Cu and Zn on growth performance of nursery pigs

2018 ◽  
Vol 2 (1) ◽  
pp. 62-73 ◽  
Author(s):  
J A Feldpausch ◽  
R G Amachawadi ◽  
M D Tokach ◽  
H M Scott ◽  
S S Dritz ◽  
...  
Keyword(s):  
Essential Oil ◽  
Growth Performance ◽  
Treatment Period ◽  
Weaned Pigs ◽  
Nursery Pigs ◽  
Nursery Pig ◽  
Pig Performance ◽  
High Doses ◽  
D 12 ◽  
Main Effects

Abstract Two 47-d experiments were conducted with 21-d-old weaned pigs (PIC 1050, initially 6.1 kg) to determine the effects of feeding low or high doses of chlortetracycline (CTC) and antibiotic alternatives (Cu, Zn, and essential oil [EO]), alone or in combination, on growth performance. On d 5 postweaning, pens of 5 pigs were allotted to diet treatments with 8 (exp. 1) or 7 (exp. 2) replicate pens per treatment. In exp. 1, treatments were fed from d 5 to 26 postweaning and arranged in a 2 × 3 factorial with main effects of added ZnO (0 vs. 2,500 ppm of Zn) and CTC (0, 55, or 441 ppm). In exp. 2, treatments were fed from d 5 to 33 and structured in a (2 × 2 × 2) + 2 factorial with main effects of added CuSO4 (0 vs. 125 ppm Cu), added ZnO (0 vs. 3,000 ppm Zn from d 5 to 12 and 2,000 ppm Zn from d 12 to 33), and Regano EX (0 vs. 0.1% Regano EX containing 5% Origanum oil). The 2 additional treatments were subtherapeutic (55 ppm) and therapeutic (441 ppm) levels of CTC. Following the treatment period, a common diet without antimicrobial was fed until d 47. All diets contained 16.5 ppm Cu and 110 ppm Zn from the trace mineral premix. In exp. 1, no ZnO × CTC interactions were observed. Feeding ZnO increased (P &lt; 0.05) ADG, ADFI, and BW during the treatment period and increased (P &lt; 0.05) ADG and ADFI overall (d 5 to 47). Pigs fed CTC had increased (linear, P &lt; 0.05) ADG, ADFI, and BW during the treatment period and had marginally significant increases (linear, P &lt; 0.10) in overall ADG and ADFI, but overall G:F tended (quadratic, P = 0.070) to increase then decrease as CTC increased. During the treatment period in exp. 2, EO did not affect ADG or ADFI, whereas pharmacological levels of Cu, Zn, and CTC increased (P &lt; 0.05) ADG with coinciding increases (P = 0.055, 0.006, and linear 0.079, respectively) in ADFI. Copper, Zn, and CTC did not affect G:F. EO decreased (P = 0.009) G:F. Diet treatments had minimal carryover effects on subsequent nursery pig growth performance. Overall from d 5 to 47, Cu increased (P = 0.018) ADG, Zn increased (P &lt; 0.05) ADG and ADFI, and EO tended to decrease (P = 0.086) G:F. In conclusion, increased dietary Cu, Zn, or CTC improved weanling pig performance while EO elicited no growth benefits. The benefits of added Zn from ZnO and CTC were additive and could be included together in diets to maximize growth performance of weaned pigs.

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