scholarly journals Interactive Tree Of Life (iTOL) v4: recent updates and new developments

2019 ◽  
Vol 47 (W1) ◽  
pp. W256-W259 ◽  
Author(s):  
Ivica Letunic ◽  
Peer Bork

Abstract The Interactive Tree Of Life (https://itol.embl.de) is an online tool for the display, manipulation and annotation of phylogenetic and other trees. It is freely available and open to everyone. The current version introduces four new dataset types, together with numerous new features. Annotation options have been expanded and new control options added for many display elements. An interactive spreadsheet-like editor has been implemented, providing dataset creation and editing directly in the web interface. Font support has been rewritten with full support for UTF-8 character encoding throughout the user interface. Google Web Fonts are now fully supported in the tree text labels. iTOL v4 is the first tool which supports direct visualization of Qiime 2 trees and associated annotations. The user account system has been streamlined and expanded with new navigation options, and currently handles >700 000 trees from more than 40 000 individual users. Full batch access has been implemented allowing programmatic upload and export of trees and annotations.

2021 ◽  
Author(s):  
Ivica Letunic ◽  
Peer Bork

Abstract The Interactive Tree Of Life (https://itol.embl.de) is an online tool for the display, manipulation and annotation of phylogenetic and other trees. It is freely available and open to everyone. iTOL version 5 introduces a completely new tree display engine, together with numerous new features. For example, a new dataset type has been added (MEME motifs), while annotation options have been expanded for several existing ones. Node metadata display options have been extended and now also support non-numerical categorical values, as well as multiple values per node. Direct manual annotation is now available, providing a set of basic drawing and labeling tools, allowing users to draw shapes, labels and other features by hand directly onto the trees. Support for tree and dataset scales has been extended, providing fine control over line and label styles. Unrooted tree displays can now use the equal-daylight algorithm, proving a much greater display clarity. The user account system has been streamlined and expanded with new navigation options and currently handles >1 million trees from >70 000 individual users.


2021 ◽  
Vol 13 (3) ◽  
pp. 80
Author(s):  
Lazaros Vrysis ◽  
Nikolaos Vryzas ◽  
Rigas Kotsakis ◽  
Theodora Saridou ◽  
Maria Matsiola ◽  
...  

Social media services make it possible for an increasing number of people to express their opinion publicly. In this context, large amounts of hateful comments are published daily. The PHARM project aims at monitoring and modeling hate speech against refugees and migrants in Greece, Italy, and Spain. In this direction, a web interface for the creation and the query of a multi-source database containing hate speech-related content is implemented and evaluated. The selected sources include Twitter, YouTube, and Facebook comments and posts, as well as comments and articles from a selected list of websites. The interface allows users to search in the existing database, scrape social media using keywords, annotate records through a dedicated platform and contribute new content to the database. Furthermore, the functionality for hate speech detection and sentiment analysis of texts is provided, making use of novel methods and machine learning models. The interface can be accessed online with a graphical user interface compatible with modern internet browsers. For the evaluation of the interface, a multifactor questionnaire was formulated, targeting to record the users’ opinions about the web interface and the corresponding functionality.


2017 ◽  
Vol 30 (04) ◽  
pp. 279-282
Author(s):  
Jörg Wichmann

AbstractSince there is great interest in new homeopathic remedies, new provings and new systems for grouping and understanding remedies, Homoeopathic Links wants to inform all homeopaths via this rubric about new developments. Proving conductors are invited to send their provings to us. We will mention the proving in the column and you can decide whether you also want the proving on the Web site (www.provings.info) and/or make it available by email. Besides sending the proving, you can also opt for an article about the proving that is restricted to 900 words (one page). In this article, you can include information on the substance, where to get the remedy, themes coming out of the proving and a very short description of the methodology.The Web site where you can find all provings is www.provings.info.Presented here is a review of Paul Anderson Theriault's landmark book ‘The Table of Animals’.


Author(s):  
Jiguang Peng ◽  
Jiale Xiang ◽  
Xiangqian Jin ◽  
Junhua Meng ◽  
Nana Song ◽  
...  

The American College of Medical Genetics and Genomics, and the Association for Molecular Pathology (ACMG/AMP) have proposed a set of evidence-based guidelines to support sequence variant interpretation. The ClinGen hearing loss expert panel (HL-EP) introduced further specifications into the ACMG/AMP framework for genetic hearing loss. This study developed a tool named VIP-HL, aiming to semi-automate the HL ACMG/AMP rules. VIP-HL aggregates information from external databases to automate 13 out of 24 ACMG/AMP rules specified by HL-EP, namely PVS1, PS1, PM1, PM2, PM4, PM5, PP3, BA1, BS1, BS2, BP3, BP4, and BP7. We benchmarked VIP-HL using 50 variants where 83 rules were activated by the ClinGen HL-EP. VIP-HL concordantly activated 96% (80/83) rules, significantly higher than that of by InterVar (47%; 39/83). Of 4948 ClinVar star 2+ variants from 142 deafness-related genes, VIP-HL achieved an overall variant interpretation concordance in 88.0% (4353/4948). VIP-HL is an integrated online tool for reliable automated variant classification in hearing loss genes. It assists curators in variant interpretation and provides a platform for users to share classifications with each other. VIP-HL is available with a user-friendly web interface at http://hearing.genetics.bgi.com/.


Author(s):  
Bharath V. N. ◽  
Adyanth H. ◽  
Shreekanth T. ◽  
Nalina Suresh ◽  
Ananya M. B.

The intelligent sockets are an advancement in approach to better the features and convenience offered by the existing switchboards. All updates to the board are done via a separately kept server for the web interface which connects to the home network. The features provided to the user can be bettered progressively via software updates. Features like timers which work in both automatic and manual mode, security aspect via surveillance and facial recognition, overload and usage logging with the help of the current sensor is provided. The data is also verified with the actual meter for accuracy and as a check for tampering. The data so gathered can also be used for prediction using machine learning. System first classifies various types of analog meters. Right now, the lbph classifier is trained to detect analog meter with needle and Analog meter with text readings.


Author(s):  
Prabha Selvaraj ◽  
Sumathi Doraikannan ◽  
Vijay Kumar Burugari

Big data and IoT has its impact on various areas like science, health, engineering, medicine, finance, business, and mainly, the society. Due to the growth in security intelligence, there is a requirement for new techniques which need big data and big data analytics. IoT security does not alone deal with the security of the device, but it also has to care about the web interfaces, cloud services, and other devices that interact with it. There are many techniques used for addressing challenges like privacy of individuals, inference, and aggregation, which makes it possible to re-identify individuals' even though they are removed from a dataset. It is understood that a few security vulnerabilities could lead to insecure web interface. This chapter discusses the challenges in security and how big data can be used for it. It also analyzes the various attacks and threat modeling in detail. Two case studies in two different areas are also discussed.


Author(s):  
Jaime Gomez ◽  
Cristina Cachero

The mostly “creative” authoring process used to develop many Web applications during the last years has already proven unsuccessful to tackle, with its increasing complexity, both in terms of user and technical requirements. This fact has nurtured a mushrooming of proposals, most based on conceptual models, that aim at facilitating the development, maintenance and assessment of Web applications, thus improving the reliability of the Web development process. In this chapter, we will show how traditional software engineering approaches can be extended to deal with the Web idiosyncrasy, taking advantage of proven successful notation and techniques for common tasks, while adding models and constructs needed to capture the nuances of the Web environment. In this context, our proposal, the Object-Oriented Hypermedia (OO-H) Method, developed at University of Alicante, provides a set of new views that extend UML to provide a Web interface model. A code generation process is able to, departing from such diagrams and their associated tagged values, generate a Web interface capable of connecting to underlying business modules.


2010 ◽  
pp. 248-266 ◽  
Author(s):  
D. Sandy Staples

This chapter describes one of the Web 2.0 technologies, Social Networking Sites (SNS). A definition of SNS is offered, as is a short history of these sites. The existing research is reviewed and organized to summarize what we know about SNS usage (from the perspectives of student use, general population use and organizational use), and what we know about the antecedents and outcomes of SNS use. The chapter concludes with discussion of new developments, challenges and opportunities. There are many opportunities for future research and organizational applications of SNS as SNS adoption grows at incredible rates.


2011 ◽  
pp. 1195-1205
Author(s):  
Muneesh Kumar ◽  
Mamta Sareen

The emergence of Internet has revolutionalized the way businesses are conducted. The impact of e-commerce is pervasive, both on companies and society as a whole. It has the potential to impact the pace of economic development and in turn influence the process of human development at the global level. However, the growth in e-commerce is being impaired by the issue of trust in the buyer-seller relationship which is arising due to the virtual nature of e-commerce environment. The online trading environment is constrained by a number of factors including web interface that in turn influences user experience. This article identifies various dimensions of web interface that have the potential to influence trust in e-commerce. The empirical evidence presented in the article is based on a survey of the web interfaces of 65 Indian e-Marketplaces.


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