scholarly journals Prevalence of albuminuria and renal insufficiency and associated clinical factors in type 2 diabetes: the Japan Diabetes Clinical Data Management study (JDDM15)

2008 ◽  
Vol 24 (4) ◽  
pp. 1212-1219 ◽  
Author(s):  
H. Yokoyama ◽  
H. Sone ◽  
M. Oishi ◽  
K. Kawai ◽  
Y. Fukumoto ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Renal Insufficiency ◽  
Data Management ◽  
Clinical Data ◽  
Clinical Factors ◽  
Management Study

Self-reported rate of eating is significantly associated with body mass index in Japanese patients with type 2 diabetes. Japan Diabetes Clinical Data Management Study Group (JDDM26)

Appetite ◽  
2012 ◽  
Vol 59 (2) ◽  
pp. 252-255 ◽  
Author(s):  
Aki Saito ◽  
Koichi Kawai ◽  
Morifumi Yanagisawa ◽  
Hiroki Yokoyama ◽  
Nobuichi Kuribayashi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Data Management ◽  
Body Mass ◽  
Clinical Data ◽  
Japanese Patients ◽  
Study Group ◽  
Management Study

scholarly journals Secular Trends in Dietary Intake over a 20-Year Period in People with Type 2 Diabetes in Japan: A Comparative Study of Two Nationwide Registries; Japan Diabetes Complications Study (JDCS) and Japan Diabetes Clinical Data Management Study (JDDM)

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3428
Author(s):  
Mizuki Takeuchi ◽  
Chika Horikawa ◽  
Mariko Hatta ◽  
Yasunaga Takeda ◽  
Rina Nedachi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Dietary Intake ◽  
Data Management ◽  
Clinical Data ◽  
Diabetes Complications ◽  
Japanese Patients ◽  
Food Groups ◽  
Management Study ◽  
Vegetables And Fruits

Background: In order to provide effective dietary guidance, it is necessary to consider dietary intake, which can change over time. This study analyzed changes in the diet of Japanese patients with type 2 diabetes over a 20-year period. Methods: We compared the results of two dietary surveys that used the food frequency questionnaire format. The first was conducted in 1996 by the Japan Diabetes Complications Study (JDCS) (n = 1509; males 53.3%), and the second in 2014–2018 by the Japan Diabetes Clinical Data Management Study (JDDM) (n = 1145; males 65.6%). Both are nationwide representative registries of outpatients with type 2 diabetes in Japan. Results: Over a 20-year period, both men and women with type 2 diabetes had a significant increase in body mass index (BMI). Nonetheless, there was only a small change in energy intake. Conversely, there was a significant increase in fat intake and thus in the fat-to-energy ratio. With regard to food groups, there was a significant increase in meat intake and a decrease in the intake of fish, soybeans/soy products, vegetables, and fruits, with a particularly significant decrease in vegetables. Conclusions: Even in Japan, an industrialized country with a stable socioeconomic environment, there were many significant changes in the dietary intake of patients with type 2 diabetes over the 20-year period.

1460-P: Type 2 Diabetes Polygenic Score in Addition to Clinical Factors for Prediction of Diabetes Incidence in an Indigenous American Population

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1460-P
Author(s):  
LAUREN E. WEDEKIND ◽  
SAYUKO KOBES ◽  
WEN-CHI HSUEH ◽  
LESLIE BAIER ◽  
WILLIAM C. KNOWLER ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetes Incidence ◽  
American Population ◽  
Clinical Factors ◽  
Polygenic Score ◽  
Prediction Of Diabetes ◽  
P Type

549-P: Renal Outcome of Patients with Type 2 Diabetes Exhibiting Normoalbuminuric Renal Insufficiency

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 549-P
Author(s):  
YUI NISHIWAKI ◽  
KO HANAI ◽  
TETSUYA BABAZONO
Keyword(s):  
Type 2 Diabetes ◽  
Renal Insufficiency ◽  
Renal Outcome

Oxidative stress pathway genes and chronic renal insufficiency in Asian Indians with Type 2 diabetes

2009 ◽  
Vol 23 (2) ◽  
pp. 102-111 ◽  
Author(s):  
Arun K. Tiwari ◽  
Pushplata Prasad ◽  
Thelma B.K. ◽  
K.M. Prasanna Kumar ◽  
A.C. Ammini ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Type 2 Diabetes ◽  
Renal Insufficiency ◽  
Chronic Renal Insufficiency ◽  
Asian Indians ◽  
Oxidative Stress Pathway ◽  
Stress Pathway

scholarly journals METFORMIN USE IN DIABETES PRIOR TO HOSPITALIZATION: EFFECTS ON MORTALITY IN COVID-19

2020 ◽  
Vol 26 (10) ◽  
pp. 1166-1172
Author(s):  
Jinghong Li ◽  
Qi Wei ◽  
Willis X. Li ◽  
Karen C. McCowen ◽  
Wei Xiong ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Severe Acute Respiratory Syndrome ◽  
Angiotensin Converting Enzyme ◽  
Clinical Data ◽  
Laboratory Data ◽  
Converting Enzyme ◽  
Angiotensin Converting Enzyme 2

Objective: Although type 2 diabetes mellitus (T2DM) has been reported as a risk factor for coronavirus disease 2019 (COVID-19), the effect of pharmacologic agents used to treat T2DM, such as metformin, on COVID-19 outcomes remains unclear. Metformin increases the expression of angiotensin converting enzyme 2, a known receptor for severe acute respiratory syndrome coronavirus 2. Data from people with T2DM hospitalized for COVID-19 were used to test the hypothesis that metformin use is associated with improved survival in this population. Methods: Retrospective analyses were performed on de-identified clinical data from a major hospital in Wuhan, China, that included patients with T2DM hospitalized for COVID-19 during the recent epidemic. One hundred and thirty-one patients diagnosed with COVID-19 and T2DM were used in this study. The primary outcome was mortality. Demographic, clinical characteristics, laboratory data, diabetes medications, and respiratory therapy data were also included in the analysis. Results: Of these 131 patients, 37 used metformin with or without other antidiabetes medications. Among the 37 metformin-taking patients, 35 (94.6%) survived and 2 (5.4%) did not survive. The mortality rates in the metformin-taking group versus the non-metformin group were 5.4% (2/37) versus 22.3% (21/94). Using multivariate analysis, metformin was found to be an independent predictor of survival in this cohort ( P = .02). Conclusion: This study reveals a significant association between metformin use and survival in people with T2DM diagnosed with COVID-19. These clinical data are consistent with potential benefits of the use of metformin for COVID-19 patients with T2DM. Abbreviations: ACE2 = angiotensin-converting enzyme 2; AMPK = AMP-activated protein kinase; BMI = body mass index; COVID-19 = coronavirus disease 2019; SARSCoV-2 = severe acute respiratory syndrome coronavirus 2; T2DM = type 2 diabetes mellitus

scholarly journals Renal insufficiency and linagliptin therapy: a case report

ABOUTOPEN ◽  
2018 ◽  
Vol 4 (1) ◽  
pp. 140-142
Author(s):  
Anna Corsi ◽  
Roberto Trevisan
Keyword(s):  
Type 2 Diabetes ◽  
Renal Insufficiency ◽  
Severe Renal Impairment ◽  
Minimal Risk ◽  
Oral Drugs ◽  
Severe Renal Failure ◽  
Good Glycemic Control ◽  
Severe Renal Insufficiency ◽  
Increased Risk

The presence of severe renal insufficiency in type 2 diabetes patients often challenges the diabetologist to prescribe a drug therapy, leading to a satisfactory glycemic balance with the minimal risk of hypoglycaemia. Diabetics with renal dysfunction present an increased risk of hypoglycemic episodes, and oral drugs are often ìcontraindications in these patients , especially if they are eliminated by the kidney. This last class of drugs requires a reduction in dosages to avoid the risk of prolonged hypoglycaemic episodes. In particular, in patients with severe renal insufficiency, metformin must be suspended in order to avoid the risk of lactic acidosis. Here we report the case of a young woman with type 2 diabetes, who quickly developed severe renal failure, unfortunately without remission. This case emphasizes the efficacy and safety of insulin-associated linagliptin for good glycemic control in patients with severe renal impairment, with marked reduction in hypoglycaemic episodes (Diabetology).

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