scholarly journals Patterns of bevacizumab use in patients with glioblastoma: an online survey among experts in neuro-oncology

2019 ◽  
Vol 7 (1) ◽  
pp. 52-58
Author(s):  
Surabhi Ranjan ◽  
Nebojša Skorupan ◽  
Xiaobu Ye ◽  
Ananyaa Sivakumar ◽  
Olga Yankulina ◽  
...  
Keyword(s):  
United States ◽  
Online Survey ◽  
Treatment Options ◽  
Radiation Therapy Oncology Group ◽  
The United States ◽  
Recurrent Glioblastoma ◽  
Newly Diagnosed ◽  
Multiple Choice Questions ◽  
Online Questionnaire ◽  
Cross Sectional

Abstract Background Bevacizumab (BEV) received accelerated FDA approval in 2009 for the treatment of recurrent glioblastoma (rGBM). Unfortunately, prospective randomized controlled phase 3 studies (AVAglio and Radiation Therapy Oncology Group 0825 in newly diagnosed, European Organisation for Research and Treatment of Cancer 26101 in rGBM) failed to show an overall survival benefit with BEV added to standard therapy. In light of these data, we aimed to capture current utilization patterns and perceived value of BEV in the treatment of GBM among experts in the field. Methods An online questionnaire comprising 14 multiple choice questions was sent out in spring 2017 to 207 oncologists/neuro-oncologists treating patients with GBM at all National Cancer Institute–designated cancer centers in the United States. Results Sixty-two of 207 (30%) invitees responded (by training, 70% neuro-oncologists, 20% medical oncologists, 10% pediatric oncologists/neuro-oncologists). Participants reported use of BEV most frequently in rGBM for control of edema (85% of respondents) and/or when no other treatment options were available (68%). BEV is rarely used in newly diagnosed GBM (<5% of cases by 78% respondents and in 5% to 10% cases by 15% respondents). Sixty-six percent of participants indicated that they thought BEV improved symptoms, 30% that it improved symptoms and survival, 3% that it had no benefit in GBM patients. Conclusion In this cross-sectional online survey we found that among neuro-oncology experts in the United States in 2017, BEV is predominantly utilized in select patients with rGBM, and is only rarely used in a small subgroup of patients with newly diagnosed GBM for control of edema. The low response rate may have introduced a nonresponse bias.

scholarly journals Knowledge and Behaviors Toward COVID-19 Among US Residents During the Early Days of the Pandemic: Cross-Sectional Online Questionnaire

10.2196/19161 ◽  
2020 ◽  
Vol 6 (2) ◽  
pp. e19161 ◽  
Author(s):  
John M Clements
Keyword(s):  
United States ◽  
Online Survey ◽  
The United States ◽  
Purchasing Behavior ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Lower Odds ◽  
Institutional Review ◽  
Point Increase ◽  
And Behaviors

Background The early days of the coronavirus disease (COVID-19) pandemic in the United States brought uncertainty in the knowledge about COVID-19 and what to do about it. It is necessary to understand public knowledge and behaviors if we are to effectively address the pandemic. Objective The aim of this study is to test the hypothesis that knowledge about COVID-19 influences participation in different behaviors including self-reports of purchasing more goods than usual, attending large gatherings, and using medical masks. Methods This study was funded and approved by the Institutional Review Board on March 17, 2020. The cross-sectional online survey of 1034 US residents aged 18 years or older was conducted on March 17, 2020. Results For every point increase in knowledge, the odds of participation in purchasing more goods (odds ratio [OR] 0.88, 95% CI 0.81-0.95), attending large gatherings (OR 0.87, 95% CI 0.81-0.93), and using medical masks (OR 0.56, 95% CI 0.50-0.62) decreased by 12%, 13%, and 44%, respectively. Gen X and millennial participants had 56% and 76% higher odds, respectively, of increased purchasing behavior compared to baby boomers. The results suggest that there is a politicization of response recommendations. Democrats had 30% lower odds of attending large gatherings (OR 0.70, 95% CI 0.50-0.97) and 48% lower odds of using medical masks (OR 0.52, 95% CI 0.34-0.78) compared to Republicans. Conclusions This survey is one of the first attempts to study determinants of knowledge and behaviors in response to the COVID-19 pandemic in the United States. A national, coordinated effort toward a pandemic response may ensure better compliance with behavioral recommendations to address this public health emergency.

scholarly journals Knowledge and Behaviors Toward COVID-19 Among US Residents During the Early Days of the Pandemic: Cross-Sectional Online Questionnaire (Preprint)

2020 ◽  
Author(s):  
John M Clements
Keyword(s):  
United States ◽  
Online Survey ◽  
The United States ◽  
Purchasing Behavior ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Lower Odds ◽  
Institutional Review ◽  
Point Increase ◽  
And Behaviors

BACKGROUND The early days of the coronavirus disease (COVID-19) pandemic in the United States brought uncertainty in the knowledge about COVID-19 and what to do about it. It is necessary to understand public knowledge and behaviors if we are to effectively address the pandemic. OBJECTIVE The aim of this study is to test the hypothesis that knowledge about COVID-19 influences participation in different behaviors including self-reports of purchasing more goods than usual, attending large gatherings, and using medical masks. METHODS This study was funded and approved by the Institutional Review Board on March 17, 2020. The cross-sectional online survey of 1034 US residents aged 18 years or older was conducted on March 17, 2020. RESULTS For every point increase in knowledge, the odds of participation in purchasing more goods (odds ratio [OR] 0.88, 95% CI 0.81-0.95), attending large gatherings (OR 0.87, 95% CI 0.81-0.93), and using medical masks (OR 0.56, 95% CI 0.50-0.62) decreased by 12%, 13%, and 44%, respectively. Gen X and millennial participants had 56% and 76% higher odds, respectively, of increased purchasing behavior compared to baby boomers. The results suggest that there is a politicization of response recommendations. Democrats had 30% lower odds of attending large gatherings (OR 0.70, 95% CI 0.50-0.97) and 48% lower odds of using medical masks (OR 0.52, 95% CI 0.34-0.78) compared to Republicans. CONCLUSIONS This survey is one of the first attempts to study determinants of knowledge and behaviors in response to the COVID-19 pandemic in the United States. A national, coordinated effort toward a pandemic response may ensure better compliance with behavioral recommendations to address this public health emergency.

scholarly journals Similarities and Differences in COVID-19 Awareness, Concern, and Symptoms by Race and Ethnicity in the United States: Cross-Sectional Survey (Preprint)

2020 ◽  
Author(s):  
Jeb Jones ◽  
Patrick S Sullivan ◽  
Travis H Sanchez ◽  
Jodie L Guest ◽  
Eric W Hall ◽  
...  
Keyword(s):  
United States ◽  
Race And Ethnicity ◽  
Online Survey ◽  
Statistical Tests ◽  
The United States ◽  
Control Measures ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Similarities And Differences ◽  
Hispanic White

BACKGROUND Existing health disparities based on race and ethnicity in the United States are contributing to disparities in morbidity and mortality during the coronavirus disease (COVID-19) pandemic. We conducted an online survey of American adults to assess similarities and differences by race and ethnicity with respect to COVID-19 symptoms, estimates of the extent of the pandemic, knowledge of control measures, and stigma. OBJECTIVE The aim of this study was to describe similarities and differences in COVID-19 symptoms, knowledge, and beliefs by race and ethnicity among adults in the United States. METHODS We conducted a cross-sectional survey from March 27, 2020 through April 1, 2020. Participants were recruited on social media platforms and completed the survey on a secure web-based survey platform. We used chi-square tests to compare characteristics related to COVID-19 by race and ethnicity. Statistical tests were corrected using the Holm Bonferroni correction to account for multiple comparisons. RESULTS A total of 1435 participants completed the survey; 52 (3.6%) were Asian, 158 (11.0%) were non-Hispanic Black, 548 (38.2%) were Hispanic, 587 (40.9%) were non-Hispanic White, and 90 (6.3%) identified as other or multiple races. Only one symptom (sore throat) was found to be different based on race and ethnicity (<i>P</i>=.003); this symptom was less frequently reported by Asian (3/52, 5.8%), non-Hispanic Black (9/158, 5.7%), and other/multiple race (8/90, 8.9%) participants compared to those who were Hispanic (99/548, 18.1%) or non-Hispanic White (95/587, 16.2%). Non-Hispanic White and Asian participants were more likely to estimate that the number of current cases was at least 100,000 (<i>P</i>=.004) and were more likely to answer all 14 COVID-19 knowledge scale questions correctly (Asian participants, 13/52, 25.0%; non-Hispanic White participants, 180/587, 30.7%) compared to Hispanic (108/548, 19.7%) and non-Hispanic Black (25/158, 15.8%) participants. CONCLUSIONS We observed differences with respect to knowledge of appropriate methods to prevent infection by the novel coronavirus that causes COVID-19. Deficits in knowledge of proper control methods may further exacerbate existing race/ethnicity disparities. Additional research is needed to identify trusted sources of information in Hispanic and non-Hispanic Black communities and create effective messaging to disseminate correct COVID-19 prevention and treatment information.

scholarly journals 2499. Perceptions of and Preferences for Oral or Long-Acting Injectable Antiretroviral Treatment Regimens in the United States and Canada

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S866-S867
Author(s):  
Cindy Garris ◽  
Sebastian Heidenreich ◽  
Erin Arthurs ◽  
Frank Spinelli ◽  
Katelyn Cutts ◽  
...  
Keyword(s):  
United States ◽  
Online Survey ◽  
Antiretroviral Treatment ◽  
The United States ◽  
Physician Satisfaction ◽  
Treatment Preferences ◽  
Cross Sectional ◽  
Pilot Survey ◽  
Dosing Frequency ◽  
Long Acting

Abstract Background Antiretroviral treatment (ART) for patients living with HIV (PLHIV) has improved greatly, however, challenges with daily oral dosing remain. New ART options with reduced dosing frequency and innovative delivery methods may help address these challenges. This study assesses patient and physician satisfaction with current treatments and preferences for switching to a monthly or every other month long-acting injectable (LAI) ART. Methods This is a cross-sectional online survey of PLHIV and physicians treating PLHIV in United States and Canada. A literature review, clinical expert input, and qualitative and quantitative pilots informed survey design. Eligible PLHIV were on ART for ≥ 6 months and virally suppressed (self-reported). Survey questions for patients evaluate satisfaction and adherence to current ART. Treatment preferences are assessed using a discrete choice experiment (DCE), where respondents choose between staying on current ART, switching to another oral ART or switching to a LAI ART. DCE treatment attributes include dosing frequency, side effects, forgivability, food/mealtime restrictions, and mode of administration. Pilot data for US patients is included here; the main survey will include approximately 550 patients and 450 physicians. Results Of 51 PLHIV completing the pilot survey, 80% were male, mean age was 54 years, and 63% were on ART for ≥10 years. Switching ART was common, with 55% reporting changing their ART ≥ 3 times. Just under half of patients (47%) were not totally satisfied with their current ART. Most common reasons for dissatisfaction included daily reminder of having HIV (31%) and having to take medicine every day (28%). Just over a quarter of patients (28%) reported forgetting to take their ART in the prior month. Across all DCE choices, patients preferred to remain on their current treatment 47% of the time, while 45% of the time patients preferred switching to the LAI, and for the remaining 8%, patients chose switching to another oral ART regimen. Conclusion Despite advances in ART, treatment challenges remain. Among the treatment-experienced PLHIV in this pilot survey, over half of their choices resulted in switching to an alternative regimen, and when opting to switch, most patients preferred the long-acting injectable treatment regimen. Disclosures All authors: No reported disclosures.

A Cross-Sectional Study of Pain Among U.S. College Music Students and Faculty

2017 ◽  
Vol 32 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Jeremy L Stanek ◽  
Kevin D Komes ◽  
Fred A Murdock
Keyword(s):  
Performing Arts ◽  
Large Scale ◽  
Online Survey ◽  
Treatment Options ◽  
The United States ◽  
Cross Sectional Study ◽  
Medical Professional ◽  
College Level ◽  
Cross Sectional ◽  
The Right

OBJECTIVES: Studies over recent decades have demonstrated significant performance-related pain among professional musicians. However, there have been no large-scale studies to evaluate pain among college musicians. The aim of this study was to determine the prevalence and anatomical locations of performance-related pain among students and faculty at the college level and learn what musicians do when they have pain. METHODS: Cross-sectional data were collected using an online survey distributed to colleges across the United States. Data were analyzed using REDCap electronic data capture tools and Microsoft Excel. RESULTS: We received 1,007 survey responses and found that 67% of musicians at colleges experienced performance-related pain. The highest prevalence of pain was in woodwind musicians, with 83% reporting performance-related pain. The most common locations of pain were upper back (27%), lower back (26%), and fingers of the right hand (25%). Many student musicians with pain seek help from their teacher, but almost as many do not seek help at all. Less than 25% see a medical professional. CONCLUSIONS: Most musicians at colleges experience performance-related pain in a variety of anatomical locations depending upon instrument/voice. Performing arts health organizations can increase awareness of treatment options for musicians suffering from performance-related pain, which may lead to improved quality of life and increased career longevity for college musicians.

scholarly journals There is a Lack of Standardization in the Collection Development and Circulation Policies of Prison Library Services

2013 ◽  
Vol 8 (2) ◽  
pp. 248
Author(s):  
Michelle Dalton
Keyword(s):  
United States ◽  
Development Policy ◽  
Online Survey ◽  
The United States ◽  
Library Services ◽  
Policy Statement ◽  
Collection Development ◽  
Correctional Institution ◽  
Online Questionnaire ◽  
Policy Statements

Objective – To explore how collection development policies currently support the role and purpose of prison libraries, and to explore if the accessibility of circulation records impacts on patron privacy. Design – Online survey questionnaire and a case study analysis of the existing policy statements of selected correctional institutions. Setting – The prison library sector in the United States. Subjects – 17 librarians and library staff across ten states in the United States. Methods – An eight-question online questionnaire was used to explore the existing collection development and circulation policies in prison libraries, and the level of adherence to the guidelines of the Association of Specialized and Cooperative Library Agencies (ASCLA) and the American Correctional Association (ACA). In addition, participants were encouraged to forward any circulation or collection development policy statements for more detailed analysis. Each policy was then reviewed to assess the degree of alignment or otherwise with the American Library Association’s (ALA) Prisoners’ Right to Read guidelines (2010). Main Results – The results of the survey found that 24% of libraries had no formal collection development policy, and at least 53% of libraries had no circulation policy statement. In these instances, the libraries were typically subject to the local policies and procedures of the correctional institution. The purpose of the library and its collection was primarily viewed as: providing recreational reading material; maintaining contact with the outside world and enabling re-entry into the community; and supporting vocational skills and lifelong learning. In selecting materials, the results indicated that a broadly similar approach to that of public libraries was adopted by most institutions, with the exception of any material that may pose a safety or security threat to the institution. In one institution the use of library services or resources for legal purposes or to provide legal assistance was also clearly prohibited in the collection development policy, although approximately half of the libraries did state that providing legal material was one of their roles. The lengthy and arduous approval process for ordering books and other materials (up to ten months in one instance) was reported by several participants due to the layers of bureaucracy and controls inherent in the prison setting. With regard to circulation records and confidentiality issues, 35% of libraries deleted such records instantly upon return of the items, compared with 30% that archived them. A further 29% only retained information from the current and most recent patrons for the purposes of assessing and charging for damaged items. Conclusion – The author found the prison library sector to be a relatively challenging environment. In this context, following the existing guidelines and best practice as recommended by the ALA and others, and establishing clear and ethical policy statements can help libraries to support the needs and rights of patrons more effectively.

scholarly journals Coping With and Adapting to COVID-19 in Rural United States and Canada

2021 ◽  
Vol 102 (1) ◽  
pp. 78-90
Author(s):  
Donna Wang ◽  
Jill M. Chonody ◽  
Kathryn Krase ◽  
Leina Luzuriaga
Keyword(s):  
United States ◽  
Health Care ◽  
Social Media ◽  
Rural Areas ◽  
Online Survey ◽  
The United States ◽  
Small Towns ◽  
Cross Sectional ◽  
Personal Impact ◽  
Levels Of Support

Guidelines aimed at slowing the spread of COVID-19 resulted in major changes in people’s lives. A cross-sectional online survey, completed by 1,405 adults in Canada and the United States in June 2020, found respondents from rural areas/small towns reported better coping and adjustment (i.e., less use of substances for support), less personal impact, less life disruption, and fewer challenges with transportation and health care, than urban and suburban respondents. Those in rural areas were less likely to use the newspaper, but more likely to use social media, for information. Finally, rural respondents reported higher levels of support for their national leadership’s response to the pandemic. The needs and strengths of rural areas, as well as approaches to serve rural areas are discussed.

scholarly journals Sleep Quality Among Informal Caregivers During the COVID-19 Pandemic: A Cross-Sectional Study

2022 ◽  
Vol 8 ◽  
pp. 233372142110573
Author(s):  
Mary L. Greaney ◽  
Zachary J. Kunicki ◽  
Meghan M. Drohan ◽  
Caitlin C. Nash ◽  
Steven A. Cohen
Keyword(s):  
United States ◽  
Sleep Quality ◽  
Caregiver Burden ◽  
Online Survey ◽  
Behavioral Science ◽  
Informal Caregivers ◽  
The United States ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
The Impact

Sleep is an integral component of health. The impact of the COVID-19 pandemic on sleep quality among informal caregivers, individuals who provide unpaid care or assistance to family members or friends, assisting older adults is not well understood. Therefore, informal caregivers in the United States providing care for individuals aged 50+ were recruited via Amazon’s Mechanical Turk, an online platform for enrolling study participants into social and behavioral science research, to complete an online survey. The sample of informal caregivers ( n = 835) was 69% male and 55% non-Hispanic. Multivariable linear regression models were constructed to assess the associations between sleep disturbance scores (SDS) and sleep-related impairment scores (SIS) and caregiving-related measures (hours caregiving/week, length of time spent caregiving, and caregiver burden), demographics, and region of the United States. The analysis determined that Black (β = 2.6, 95% CI [−4.3, −0.9]) and Asian informal caregivers (β = −1.8, 95% CI [−3.4, −0.3]) had lower mean SIS than White caregivers, the referent group. In addition, increasing caregiver burden was associated with increased SDS (β = 0.8, 95% CI [0.6, 1.0]) and SIS (β = 1.3, 95% CI [0.7, 1.6]). In conclusion, higher caregiver burden was associated with higher SIS and SDS, suggesting that informal caregivers' sleep should be assessed, and when needed interventions should be offered.

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