Women are obliged to take on vulnerable forms of employment that fail to protect their basic labor rights. Exposure to workplace violence is especially high for those women who work within the agriculture, the hotels, restaurants and catering, the transport as well as the manufacturing sectors. In this context, we explored workplace violence against women working as waitresses in various hotels, restaurants, cafeterias and grocery stores of Wolaita Sodo town, southern Ethiopia. Cross-sectional study was undertaken with descriptive and exploratory study designs. Qualitative data were collected by using in-depth interview method in which 16 waitresses were interviewed. Data were voice recorded, transcribed, and analyzed searching themes and patterns in the data. While we found that waitresses are highly exposed to workplace violence, the level of exposure to the violence varies across various circumstances, including working in large and small towns, the situation of the owners/supervisors, public’s insight of the position, waitresses’ ability to speak the local language, the role of the waitresses, customers’ behavior and the specific context in which waitresses work. Waitresses were generally exposed to all forms of violence including spitting, throwing objects, simple physical assault, touching on private parts, and intimidation, among which verbal abuse and emotional exploitations are found to be the most common. Furthermore, the results revealed that though waitresses rarely experienced violence from female customers, the most common perpetrators involved in the practice were males. Amid widespread exposure of waitresses to all forms of workplace violence, ignorance, mostly motivated by fear of losing one’s job, has been the common way waitresses respond to the violence. The study implies the vulnerability state of waitresses partly due to lack of adequate awareness regarding the rights and obligations expected of an employee when working in such organizations. This is again exacerbated by the lack of formal employment procedures in such organizations. Therefore, awareness creation and supervisory activities are expected from the media, workers’ and social security office of the government, police and other concerned bodies.