Breast lump

Author(s):  
Hugo Farne ◽  
Edward Norris-Cervetto ◽  
James Warbrick-Smith

The four most common diagnoses for a breast lump are: • Benign cystic change (also known as fibrocystic change, fibroadenosis, or benign breast change) • Fibroadenoma • Cyst • Carcinoma If we consider women of all ages, there are a number of other potential diagnoses: • Fat necrosis • Periductal mastitis • Abscess • Galactocele • Phyllodes tumour • Sarcoma • Duct papilloma • ‘Non-breast’ lumps, e.g. lipoma, sebaceous cyst, prominent costal cartilage/rib. The age of the patient is one of the most useful pieces of information for narrowing the differential. As an approximate guide, the most common diagnoses in the following age groups are: • <30 years: physiologically normal lumpy breast; benign cystic change; fibroadenoma; abscess (if breast-feeding); galactocele (if breast-feeding) • 30–45 years: benign cystic change; cyst; abscess (especially smokers); carcinoma • 45–60 years: cyst; abscess (smokers); carcinoma • >60 years: carcinoma ▲ Note: It is worth emphasizing that breast cancer is possible in all ages, is common, and is potentially very serious. Therefore you must exclude it in any presentation of breast lump, regardless of how benign it seems. Failure to diagnose breast cancer is one of the most common malpractice claims in the USA. Galactoceles may occur during or shortly after the cessation of lactation. They may present as a firm mass (often subareolar) and are caused by the obstruction of a lactiferous duct. The duct gradually becomes more distended with milk and epithelial cells, and may rarely be complicated by a secondary infection leading to abscess formation. Clinically, a galactocele is very similar to a cyst on examination. In addition, lactating women are predisposed to mastitis (whether or not they have a galactocele). The causative organisms are usually skin commensals such as Staphylococcus aureus or Staphylococcus epidermidis—this is in contrast to the periductal mastitis and abscess formation seen in older women, in whom anaerobic bacteria may also be implicated. Two of the greatest risk factors for breast cancer are being female and increasing age. Otherwise, the following are recognized as important factors: • Previous breast cancer • Family history of breast cancer. Suspicions should be raised if: ■ Three close blood relatives (on the same side of the family) develop breast cancer at any age

2020 ◽  
Vol 11 (3) ◽  
pp. 554-558
Author(s):  
Ishwari Sanjay Gaikwad ◽  
Pradnya Deepak Dandekar

Background: Breast lump is considered as carcinogenic unless it is tested and diagnosed other than this. Today in India, it is one of the leading causes of cancer deaths among women. Only early detection and early medical intervention could decrease its mortality rate.  Knowledge and awareness of palpation of breast lumps and attitude to get diagnosed at earliest is very important. Aim and Objectives: The study is designed to assess knowledge, awareness and attitude towards screening of Breast lumps among females. Materials and Methods: It is a questionnaire based an observational study. Those females above age of 14 years; attending Hospital were selected for the study with their consent. Data was collected by using self-structured and validated questionnaire. Total 100 females’ data was collected and analysed. Observation and Result: Of the total sample, approximately 89% of subjects were found to have heard of Breast Cancer and 41% had knowledge that Breast lump may be a sign of Breast Cancer. 22% females have heard about Breast self-examination (BSE) as an early diagnostic tool. Only 8 %& 14 % knew about importance of Clinical Breast examination (CBE)& mammography respectively. Awareness towards screening was found to be very low. Conclusion: The results revealed that, although knowledge about Breast lump is adequate up to certain limit but they do not have a comprehensive understanding of the condition. Thus, there is an urgent need to promote knowledge, awareness and health literacy among the society.


2020 ◽  
Vol 15 (2) ◽  
pp. 13-17
Author(s):  
Zena Kassim Mohamed

Background: Breast lump is one of the most common prevalent complaint of patients attending breast clinics. Objective: To determine if there is any change in the pattern of common breast, diseases presenting as breast lumps between pregnant and non-pregnant women among patients attending Al-Elwiya Breast Clinic. Methods: This is a cross – sectional study, with convent's patient sampling setting in AL-Elwiya Breast Cancer Early Detection Clinic from 1st Feb. to 1st May 2018, we collected data from patients with breast lumps including the age groups, pregnancy status, parity status, previous breast diseases, hormonal drugs, menstrual cycle, breast feeding. Breast lump was examined, sonography and needle biopsy, and histopathology. Results:  This study involves 306 married patients, fibro adenoma was the commonest pathology in the age group 20-29 year-old (29.9%) followed by Aberration of Normal Development and Involution which was found mainly in 30-39-year-old age group (36.1%). Carcinoma found mainly in the >40-year-old age group (10.3%). Aberration of Normal Development and Involution was the main pathology in non-pregnant patients (36.1%), in pregnant patients fibro adenoma is the commonest (35.7%). Conclusion: The majority of breast lumps are benign. In pregnant women, fibro adenoma is the commonest, while in non-pregnant women, Aberration of Normal Development and Involution is the main cause of breast lumps


2019 ◽  
Vol 6 (10) ◽  
pp. 3655
Author(s):  
Noor Hassan Hussian ◽  
Pradip Kumar Mohanta ◽  
Subikash Biswas ◽  
Siddhabrata Besra ◽  
Sabuj Pal ◽  
...  

Background: The pathogenesis involves disturbance in the breast physiology extending from an extreme normality to well defined disease processes. The clinician must provide a degree of diagnostic accuracy while at same time ensuring that an excessive biopsy rate is prevented. The aim of this study was to evaluate the benign breast lumps in different age groups and to determine the prevalence of benign breast lumps among the breast symptomatic.Methods: This clinico-pathological cross sectional study was conducted with a sample size of 100. The study was conducted during the period from July 2018 to June 2019 which included all patients presenting with benign breast lump during the study period.Results: Out of 100 studied cases of benign breast diseases, the most common benign breast tumor found as fibro adenoma and majority of the fibro adenoma found in the 2nd and 3rd decade of life. Right breast and upper outer quadrant were most commonly affected. Majority of benign breast lesions presented with painless lump in the breast and most of them were from rural background. Majority of benign Breast lumps (45%) cases were found in the age group of 21-30 years. Majority of the patients (60%) attain menarche between ages 13-15 years. Majority of cases (55%) were belonged to lower socio economic status.Conclusions: Our study indicates that FNAC is diagnostically more accurate, safe, cost effective and OPD procedure, however when FNAC was inconclusive, biopsy is the best choice for breast tumors.


2016 ◽  
Vol 7 (3) ◽  
pp. 58-64 ◽  
Author(s):  
Ogbuanya Aloysius Ugwu-Olisa ◽  
Anyanwu Stanley Nnamdi ◽  
Nwigwe Chinedu Gregory ◽  
Iyare Festus

Aims and Objectives: Breast lumps are quite common, but the principal issue is differentiating malignant from the benign sub-groups. The determinants of histologic diagnosis are multifactorial, ranging from environmental, genetic to sex and age-related factors. This study aimed to document the spectrum of breast lumps in our environment.Materials and Methods: This is a descriptive prospective analysis of consecutive breast lumps biopsied at Federal Teaching Hospital Abakaliki, between December 2010 to November 2012. The data were analysed using statistical package for social sciences (SPSS) version 22.0Results: A total of 302 patients with 359 breast lumps were seen, 298 females and 4 males giving male: female ratio of 1:75.The ages of the patients ranged between 16-82 years with a mean of 37.0 +/- SD 13.0. Majority (56.3%) of the patients had benign lumps. Fibroadenoma was the commonest (33.8%), followed closely by invasive ductal carcinoma (32.8%), then fibrocystic change (17.2%).The occurrence of breast cancer was strongly age-related, being 1 in 5 biopsies at 20-29 years and 3 in 5 biopsies at 40-49 years age groups. Over two-third (69.0%) of 132 patients with breast cancers were premenopausal. Majority (78.8%) of the 132 patients with breast cancer presented with advanced disease. At a median follow up of 9 months,13 (9.8%) and 6(4.5%) of 132 cancer patients developed recurrences and new cancer sites respectively.Conclusion: Most patients with breast complaints present with lumps and majority are benign, fibroadenoma being the commonest histology. Occurrence of breast cancer is strongly age-related with majority of cancer patients presenting late.Asian Journal of Medical Sciences Vol. 7(3) 2016 58-64


2011 ◽  
Vol 1 (3) ◽  
Author(s):  
Emine Devolli Disha ◽  
Suzana Manxhuka Kerliu ◽  
Zana Baruti Gafurri ◽  
Valdete Topciu ◽  
Bukurije Zhubi ◽  
...  

Introduction: Aim of the study was to discern which are more frequent symptoms presented in malign and benign masses diagnosed by mammography and ultrasonography.Methods: Our study group consisted of 546 female patients, with breast symptoms such as palpable lumps (40.8%), pain in the breast (26%), localized lumpiness or nodularity (13.7%), nipple retraction (11.2%), nipplebloody discharge (5.1%) and redness and swelling of the breast (3.1%). All 546 patients were examined by ultrasonography and mammography. Biopsy was performed according to the findings of mammography and ultrasonography.Results: In breast cancer detection ultrasonography showed an efficiency of 79.4% compared to 55.0% for mammography in detecting breast lump, in the case of nipple retraction mammography showed an efficiency of 89.1% compared to 80.4% for ultrasound, while the lowest efficiency for mammography was in the cases with localized lumpiness or nodularity 17.1% compared to 45.7% for ultrasound. In detecting fibrocystic changes where the most common symptoms was pain, ultrasonography showed an efficiency of 99.3 % compared to 84.2 % for mammography.Conclusions: Our study confirmed that breast lumps are detectable in the majority of patients with breast cancer. The most frequent symptoms in patient with benign lesions were pain or localized discomfort. The diagnostic accuracy for carcinomas of the breast and for benign lesions according to symptoms was higher for ultrasound than for mammography.


2020 ◽  
Vol 23 (1) ◽  
pp. 10-12
Author(s):  
Nelema Jahan ◽  
Md. Mamunur Rahman ◽  
Mohammad Shahidul Alam ◽  
Md Saiful Islam

Background: A breast lump is the most common symptom associated with both benign and malignant breast diseases. Therefore, a distinction of benign from malignant lump is of importance for proper management. Though a definitive diagnosis is possible with imaging for all the lesions, histopathological study is proven essential for confirming the diagnosis. Objective: The objective of this study was to evaluate the role of USG and histopathological findings of different breast lump in diagnosis and their comparison. Methods: A prospective study was conducted over a period of one year from January 2017 to December 2017. A total of 116 patients were included in this study. All breast lumps underwent surgery and the ultrasound findings of these lumps were compared with the histopathological findings. Data were collected from these patients by a preformed questionnaire and finally the data were analyzed. Results: Out of 116 patients only 21 cases were reported as malignant in ultrasound report but histopathology revealed 31 malignant patients. On histopathological examination 10 benign cases turned out to be malignant. Conclusion: The present study was undertaken to evaluate in diagnosing breast mass lesions individually by ultrasound and compared with histopathology for definitive management of a patient. Journal of Surgical Sciences (2019) Vol. 23 (1) : 10-12


2020 ◽  
Vol 17 (2) ◽  
pp. 187-192
Author(s):  
E.A. Novikova ◽  
◽  
O.V. Kostromina ◽  
D.V. Mikhailov ◽  
S.L. Leontiev ◽  
...  

Aim. The aim of the study was to determine the presence of peculiarities of the age structure in patients with various surrogate molecular biological subtypes of breast cancer. Materials and research methods. This work analyzes the age-related characteristics of the occurrence of molecular biological subtypes in 499 patients with invasive breast cancer. All cases were divided into 5 molecular biological subtypes based on immunohistochemical studies of hormone receptors, Her2, Ki-67. The average age of the patients was 53.4±0.39 years, the predominant group was patients from 50 to 60 years (37.2% of the total). Research results. In patients under 40 years old, the triple negative subtype prevailed (44.8%). Luminal A subtype prevailed in the groups 51-60 years old (more than 41.4%) and over 60 years old (39.7%). Luminal B (Her2-) subtype was equally found in all age groups.


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