scholarly journals M38. PATIENT-PERSPECTIVE: NEED FOR CARE AFTER A FIRST PSYCHOSIS

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S148-S149
Author(s):  
Inge Heijden-Hobus ◽  
Inge van der Heijden-Hobus ◽  
Bram-Sieben Rosema ◽  
Jacob Vorstman ◽  
Martien Kas ◽  
...  

Abstract Background Only little is information is available about the needs and preferences regarding care and treatment of people who are going through a psychosis for the first time. A first psychotic episode is often an intense experience, which may not directly be recognized as a mental health problem. Given the unfamiliarity with the available options of care, it probably differs from subsequent psychoses. In order to design first psychosis programs to optimally meet patients preferences, we need to learn the care needs of these usually young people. Furthermore, peoples’ needs during the first psychosis, and the need for care after a psychotic episode have to be explored, in order to be able picking up life again after complete or incomplete remission. Methods Qualitative interviews were conducted with people (n = 20) who are in complete or partial remission after their first psychosis about their personal care needs. Interviews were conducted by an experience expert and a researcher together and lasted between 1 and 3 hours. Interviews were non-structured, but a basic set of 5 topics was used. Results Preliminary results of the interviews conducted so far (n = 14) show that people with a first psychosis have a great need for information about the symptoms they are suffering from. In addition, they believe that medication is an important ‘cornerstone’ to get rid of their symptoms. Furthermore, nearly all participants hope to be able to stop medication in the near future. Admission to a ward is in most cases experienced as frightening. One person indicated that the tranquility during admission was very welcome. At this stage, experience experts are not being reached out to yet, nor is there a clear need for social work in this stage of the disease. During and shortly after their first psychosis, the interviewees especially appreciate the support of family and close friends. Discussion Clear information about a first psychosis was mentioned as the first need. Family and close friends are most appreciated as “auxiliary troops”. Family support is therefore an important contributor in care for patients suffering from psychosis. Medication was appreciated as an important cornerstone, but only to induce remission, not as a mean for maintenance treatment. Admission was by most patients experienced as stressful. Additional research is recommended to further map what information this should be exactly, and how to bring it to the patient and his relatives.

2018 ◽  
pp. 47-52

Epimedium elatum (Morren & Decne) of family Berberidaceace is a rare perennial medicinal plant, endemic to high altitude forests of Northwestern Himalayas in India. Ethnobotanically, it has been used as an ingredient for treatment of bone-joint disorders, impotence and kidney disorders in Kashmir Himalayas. Phytochemically, it is rich in Epimedin ABC and Icariin; all of these have been demonstrated to possess remarkable biological activities like PDE-5 inhibition (treatment of erectile dysfunction), anticancer, antiosteoporosis antioxidant and antiviral properties. The present investigation reports its traditional usage, comprehensive distribution and conservation status from twenty ecogeographical regions in Kashmir Himalayas, India. The species was reported from Gurez valley for the first time. Numerous threats like excessive grazing, deforestration, habitat fragmentation, tourism encroachment, landslides and excessive exploitation have decreased its natural populations in most of the surveyed habitats. Consequently, its existence may become threatened in near future if timely conservation steps are not taken immediately by concerned stakeholders involved in medicinal plant research. Moreover, use of plant tissue culture techniques is recommended for development of its in vitro propagation protocols. Therefore, introduction of this medicinal plant in botanical gardens, protected sites and development of monitoring programmes are needed for its immediate conservation in Northwestern Himalayas, India.


1994 ◽  
Vol 59 (1) ◽  
pp. 1-74 ◽  
Author(s):  
Pavel Kočovský

This review summarizes the main topics of our research and covers the period of the last 15 years. The prime interest is focused on various ways of controlling the regio- and stereoselectivity of selected organic reactions, in particular electrophilic additions, cleavage of cyclopropane rings, and allylic substitutions by means of neighboring groups and/or transition and non-transition metals. In the first part, the factors governing the course of electrophilic additions are assessed, culminating in the formulation of selection rules for the reactivity of cyclohexene systems, and in a concise synthesis of the natural cardioactive drug, strophanthidin. These studies also contribute to a better understanding of the mechanisms of electrophilic additions. The second part describes recent developments in the stereo- and regiocontrolled cleavage of cyclopropane rings by non-transition metals (Tl and Hg), and the reactivity and transmetalation (with Pd) of the primary products. This methodology has resulted in novel routes to unique polycyclic structures, and will have synthetic applications in the near future. Evidence for the stereospecific "corner" cleavage of the cyclopropane ring has been provided for the first time for Tl and later for Hg. The third part deals with transition metal-catalyzed allylic substitution. Evidence for a new "syn" mechanism for the formation of the intermediate (π-allyl)palladium complex has been provided, which runs counter to the generally accepted "anti" mechanism. A novel method for a Pd-catalyzed allylic oxidation has been developed and employed in the synthesis of natural sesquiterpenes. The increasing importance of transition and non-transition metals for synthetic organic chemistry is demonstrated by their unique reactivity in a number of the papers included in this review.


2018 ◽  
Vol 59 ◽  
pp. 109-133
Author(s):  
Senem Aydın-Düzgit ◽  
Evren Balta

AbstractThis article aims to explore the views of the Turkish elite on the state of polarization in Turkey. By identifying four political frames—namely, harmony, continuity/decline, conspiracy, and conflict—that selected Turkish political and civil society elites use in discussing the phenomenon of polarization in the country through their contributions to a workshop and in-depth qualitative interviews, the article finds that there is a considerable degree of polarization among the Turkish elite regarding their views on the presence of polarization in Turkey. Moreover, this overlaps with the divide between the government and the opposition in the country. An analysis of the justificatory arguments employed in constituting the aforementioned frames shows that, while those elites who deny the existence of polarization seek its absence in essentialist characteristics of society, in reductionist comparisons with history, or in internal/external enemies, those who acknowledge polarization’s presence look for its roots in political and institutional factors and processes. The article highlights how, given the denial of polarization by the pro-government elite and the substantial gap between the two camps’ justificatory narratives, the currently reported high rates of polarization in Turkey can, at best, be expected to remain as is in the near future, barring a radical change in political constellations.


2010 ◽  
Vol 117 (2-3) ◽  
pp. 448-449
Author(s):  
Yuliya Zaytseva ◽  
Nataliya Korsakova ◽  
Isaac Gurovich ◽  
Andreas Heinz ◽  
Michael Rapp

1992 ◽  
Vol 285 ◽  
Author(s):  
S.H.H. Naqvi ◽  
M. Vickers ◽  
S. Tarling ◽  
P. Barnes ◽  
I.W. Boyd

ABSTRACTThe lead based superconductor Pb2Sr2Y0.5Ca0.5Cu3O8+δ is a most complex material. If any oxygen is present in the PbO-CuOδ-PbO sandwich layer (i.e. if δ>0) the superconductivity deteriorates. This is also a most difficult material to grow not only because of the large number of cation stoichiometries which have to be precisely balanced but also because of the tendency for multiple phases to form. Pulsed laser deposition (PLD) has been applied to prepare thin films of the 2213-phase on MgO (100) single crystal substrates at low temperature (300°C) in low oxidizing atmospheres. A basic set of ex-situ growth conditions has been determined which produce for the first time good quality films of this material as characterized by DC resistivity using the Van der Pauw method, as well as EDX and XRD. The layers are reasonably c-axis oriented and display a superconducting onset transition temperature of 79K and zero resistance at 65K after subsequent annealing in a nitrogen ambient.


2007 ◽  
Vol 17 ◽  
pp. S576-S577
Author(s):  
E. Del Moral ◽  
A. Palomino ◽  
C. Matute ◽  
J. Palomo ◽  
S. ´ Alvarez de Eulate ◽  
...  

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Manuela Temmer

AbstractThe Sun, as an active star, is the driver of energetic phenomena that structure interplanetary space and affect planetary atmospheres. The effects of Space Weather on Earth and the solar system is of increasing importance as human spaceflight is preparing for lunar and Mars missions. This review is focusing on the solar perspective of the Space Weather relevant phenomena, coronal mass ejections (CMEs), flares, solar energetic particles (SEPs), and solar wind stream interaction regions (SIR). With the advent of the STEREO mission (launched in 2006), literally, new perspectives were provided that enabled for the first time to study coronal structures and the evolution of activity phenomena in three dimensions. New imaging capabilities, covering the entire Sun-Earth distance range, allowed to seamlessly connect CMEs and their interplanetary counterparts measured in-situ (so called ICMEs). This vastly increased our knowledge and understanding of the dynamics of interplanetary space due to solar activity and fostered the development of Space Weather forecasting models. Moreover, we are facing challenging times gathering new data from two extraordinary missions, NASA’s Parker Solar Probe (launched in 2018) and ESA’s Solar Orbiter (launched in 2020), that will in the near future provide more detailed insight into the solar wind evolution and image CMEs from view points never approached before. The current review builds upon the Living Reviews article by Schwenn from 2006, updating on the Space Weather relevant CME-flare-SEP phenomena from the solar perspective, as observed from multiple viewpoints and their concomitant solar surface signatures.


2020 ◽  
Vol 13 (12) ◽  
pp. e240088
Author(s):  
Peter M Haddad ◽  
Majid Al Abdulla ◽  
Javed Latoo ◽  
Yousaf Iqbal

A 30-year-old man with no significant previous or family psychiatric history became severely anxious about his health after a positive COVID-19 test. Physical symptoms of COVID-19 were mild, with no evidence of hypoxia or pneumonia, throughout his illness. He was admitted to a quarantine facility. He remained highly anxious, and 1 week later, he developed paranoid delusions and auditory hallucinations (his first psychotic episode). He was treated with lorazepam 1 mg four times a day, mirtazapine 30 mg nocte and risperidone 1 mg two times a day. His psychotic symptoms lasted 1 week. He stopped psychiatric medication after 4 weeks and had remained well when reviewed 3 months later. A Diagnostic and Statistical Manual of Mental Disorders fifth edition diagnosis of brief psychotic disorder with marked stressor (brief reactive psychosis) was made. Anxiety about his health and social isolation appeared the main aetiological factors but an inflammatory component cannot be excluded. The case highlights that first episode psychosis can be associated with mild COVID-19.


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