scholarly journals Association between shift work and biological factors including FGF-23, klotho, and serum 25-(OH) vitamin D3 among Korean firefighters: a cross-sectional study

SLEEP ◽  
2020 ◽  
Vol 43 (10) ◽  
Author(s):  
Jeehee Min ◽  
Tae-Won Jang ◽  
Yeon Soon Ahn ◽  
Chang Sun Sim ◽  
Kyoung Sook Jeong
Keyword(s):  
Shift Work ◽  
Cancer Progression ◽  
Vitamin D3 ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Health Habits ◽  
Cross Sectional ◽  
Shift Workers ◽  
Potential Risk Factors ◽  
Fgf 23

Abstract Study Objectives Shift work is known to be detrimental to an individual’s health as it disrupts the circadian rhythm and is a risk factor for cancer. It has been reported that elevated fibroblast growth factor (FGF)-23, increased serum soluble α-klotho, and decreased vitamin D3 are associated with cancer progression. We studied the relationship between shift work and the levels of FGF-23, α-klotho, and vitamin D3 amongst firefighters, as they work in long shifts outside the traditional daytime schedule. Methods The study consisted of 450 participants who were firefighters. We measured FGF-23, α-klotho, and vitamin D3 levels in their blood and a set of questionnaires were given to the participants to evaluate their health habits. After determining and adjusting for potential confounding factors, we compared the levels of FGF-23, α-klotho, and serum vitamin D3 by job and shift types. Results FGF-23 and α-klotho levels were significantly higher in shift workers than traditional day workers, and in 3-day cycle shift workers than workers with another shift schedule. When the levels of these substances were compared based on different types of jobs, firefighters had a lower level of vitamin D3. We conclude that shift work is positively correlated with the levels of FGF-23 and α-klotho. Conclusions Levels of FGF-23 and α-klotho were linked to shift work and job types. Although vitamin levels did not differ by shift types, vitamin D3 levels were lower in firefighters. These findings suggest that high levels of FGF-23 and α-klotho are potential risk factors for cancer among firefighters.

scholarly journals Shift Work and Dry Eye Disease in the Korean Working Population: A Population-Based Cross-Sectional Study

2021 ◽  
Vol 18 (10) ◽  
pp. 5492
Author(s):  
Joonho Ahn ◽  
So-Jung Ryu ◽  
Jihun Song ◽  
Hyoung-Ryoul Kim
Keyword(s):  
Shift Work ◽  
Dry Eye ◽  
Population Based ◽  
Cross Sectional Study ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Chi Square ◽  
Cross Sectional ◽  
Shift Workers ◽  
Chi Square Test

This study aimed to evaluate the association between shift work and dry eye disease (DED) in the general population. The 2011 Korea Health Panel (KHP) was used. Chi-square test and multivariate logistic regression were used to assess the relationship between shift work and DED. Stratification analysis was conducted by sex and age. Overall, the odds ratio (OR) of DED according to shift work did not showed significant results (adjusted OR = 1.230, 95% CI 0.758–1.901). When findings were stratified based on age older or younger than 40 years, the OR of DED increased to 2.85 (95% CI: 1.25–5.90) in shift workers under 40 years of age. Our results show an association between shift work and DED in a group of younger subjects.

Serotonin variations and sleep disorders among shift workers. A cross-sectional study

2021 ◽  
pp. 074823372110331
Author(s):  
Rehab Shehata Abdelhady Shehata ◽  
Zeinab Ahmed Mohamed Nour ◽  
Amul Mohamed Abdelrahim Badr ◽  
Eman Mahmoud Khalifa
Keyword(s):  
Sleep Quality ◽  
Shift Work ◽  
Night Shift ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Serotonin Level ◽  
Poor Sleep Quality ◽  
Cross Sectional ◽  
Shift Workers ◽  
Blood Serotonin

Sleep disorders are prevalent occupational health problems among shift workers, especially healthcare workers with long shifts. Serotonin is a neurotransmitter related to circadian variations accompanied by shift work. A cross-sectional study was performed on 73 nurses at a tertiary hospital in Cairo, Egypt, to assess sleep quality among shift work nurses (SWNs), to determine blood serotonin level, and its relation to shift work and sleep quality. A demographic and occupational history questionnaire, Pittsburgh Sleep Quality Index (PSQI) questionnaire, and measurement of blood serotonin were carried out to the studied group. The data were analyzed using SPSS 25, and descriptive statistics, unpaired t-test, ANOVA, Kruskal–Wallis Test, Chi-square, Spearman correlation, and multivariate regression analysis were utilized. The results showed that the mean PSQI global score was significantly higher among SWNs than non-shift work nurses (NSWNs) and was the highest (10.32 ± 3.56 and 10.22 ± 2.4, respectively) among rotatory and fixed night shift nurses. Blood serotonin showed highly significant differences between SWNs over NSWNs ( p = 0.001), and mostly reduced among rotatory and fixed night shift nurses (66.7% and 65%, respectively). Moreover, there were highly significant differences in serotonin levels between poor and good sleep quality nurses ( p < 0.001), and most of the poor sleep quality nurses (62.7%) had low serotonin levels. Abnormal serotonin level (odds = 246.5) and working years (odds = 1.2) were statistically significant predictors of poor sleep quality. In conclusion, SWNs, especially rotating and night shift nurses, suffer from poor sleep quality associated with abnormal levels of blood serotonin.

Relationship of work-related stress with obesity among Brazilian female shift workers

2020 ◽  
pp. 1-7
Author(s):  
Janaína Cristina da Silva ◽  
Anderson Garcez ◽  
Gabriela Herrmann Cibeira ◽  
Heloísa Theodoro ◽  
Maria Teresa Anselmo Olinto
Keyword(s):  
Shift Work ◽  
Night Shift ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Work Related Stress ◽  
Shift Workers ◽  
Night Shift Work ◽  
Work Related ◽  
Prevalence Of Obesity ◽  
Related Stress

Abstract Objectives: To explore the relationship between work-related stress and obesity among female shift workers. Additionally, we also aimed to test the interaction between shift work and work-related stress in this association. Design: A cross-sectional study was conducted among Brazilian female shift workers. Work-related stress was assessed through a demand–control questionnaire (Job Stress Scale). Work-related stress was defined by the presence of high psychological demands and low control at work. The obesity cases were defined as those with a BMI of 30 kg/m2 or more. Multivariate Poisson regression with robust variance was used to obtain the prevalence ratios (PR) and their respective 95 % CI. Setting: A group of industries located in southern Brazil in 2017. Participants: Four hundred and twenty female workers aged 18–59 years. Results: The overall prevalence of obesity was 30 % (95 % CI: 25·6, 34·4), and the presence of work-related stress was identified in 24 % (95 % CI: 19·9, 28·1) of the sample. We found an indication of interaction between work-related stress and night shift work on obesity (P = 0·026). After adjusting for confounding factors, work-related stress was associated with a 71 % greater probability of obesity (PR = 1·71; 95 % CI: 1·02, 2·87; P = 0·042) among female night shift workers. Conclusions: In this study, we revealed that exposure to work-related stress and night shift work were associated with obesity among female shift workers. Furthermore, the prevalence of obesity was high among female shift workers.

scholarly journals Overweight and obesity in shift workers: associated dietary and lifestyle factors

2020 ◽  
Vol 30 (3) ◽  
pp. 532-537
Author(s):  
Victoria M O’Brien ◽  
Fiona M Nea ◽  
L Kirsty Pourshahidi ◽  
M Barbara E Livingstone ◽  
Laura Bardon ◽  
...  
Keyword(s):  
Shift Work ◽  
Metabolic Diseases ◽  
Cross Sectional Study ◽  
Overweight And Obesity ◽  
The European Union ◽  
Related Factors ◽  
Cross Sectional ◽  
Shift Workers ◽  
Lifestyle Behaviours ◽  
Fried Foods

Abstract Background Approximately 17% of the European Union workforce is engaged in shift work. Shift work has been associated with a number of chronic conditions, including obesity and obesity-related metabolic diseases. The aim of this study was to explore the dietary and lifestyle behaviours of shift workers with a healthy vs. overweight/obese body mass index (BMI). Methods A cross-sectional study was conducted on 1080 shift workers using a 15-min, telephone-administered questionnaire developed from qualitative research on Irish shift workers and national dietary intake data. Demographic and work-related factors, as well as dietary and lifestyle behaviours were recorded. BMI was calculated using self-reported height and weight. Univariate and multivariate logistic regression methods were used to analyze data according to BMI category. Results Over 40% of shift workers were classified as overweight or obese. Multivariate analysis indicated that being male [P &lt; 0.001, aOR = 2.102, 95% CI (1.62–2.73)] and middle- or older-aged were independently associated with overweight and obesity [P &lt; 0.001, aOR = 2.44 95% CI (1.84–3.24) and P &lt; 0.001, aOR = 2.9 95% CI (1.94–4.35), respectively]. Having a medium–high consumption of fried foods was independently associated with overweight and obesity [aOR = 1.38, 95% CI (1.06–1.8)]. Conclusions Similar to the general population, overweight and obesity were strongly associated with male sex and middle- or older-age. Male shift workers may benefit from targeted dietary and lifestyle advice specifically focused on limiting fried foods to help protect against overweight and obesity.

scholarly journals The Effects of Uric Acid, Serum Vitamin D3, and Their Interaction on Parkinson’s Disease Severity

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Rokhsareh Meamar ◽  
Pooria Shaabani ◽  
Seyed Reza Tabibian ◽  
Mohammad Reza Aghaye Ghazvini ◽  
Awat Feizi
Keyword(s):  
Vitamin D3 ◽  
Negative Relationship ◽  
Serum Vitamin ◽  
Rank Correlation ◽  
Positive Association ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Referral Hospitals ◽  
The One

Objectives. In current study, the relationships between serum vitamin D3 levels and serum UA concentrations as well as their interaction with severity of PD were evaluated in a sample of Iranian PD patients.Method. In a cross sectional study at the one of the main referral hospitals in central region of Iran, during September to November 2011, 112 patients were recruited. Severity of PD was evaluated sing H&R stages and UPDRS.Results. The Spearman rank correlation coefficient suggests the negative significant association between serum vitamin D3 and UPDRS in patients aged >62 (r=-0.34,P<0.05). No statistically significant association was observed between the UA levels and severity of PD (represented by H&Y categories) in different levels of serum vitamin D3 not only in total sample but also in separate age and sex groups. The linear regression coefficients suggested positive association between UA and serum vitamin D3 with UPDRSIII scores while negative relationship between UA and serum vitamin D3 interaction with UPDRSIII; however it was only statistically significant in age group ≤62 (P<0.05).Conclusion. Our study revealed a negative correlation between interaction of serum vitamin D3 and UA with severity of PD; other studies are required to confirm our findings.

scholarly journals High HOMA-IR Index in Healthcare Shift Workers

Medicina ◽  
2019 ◽  
Vol 55 (5) ◽  
pp. 186 ◽  
Author(s):  
Caterina Ledda ◽  
Diana Cinà ◽  
Serena Matera ◽  
Nicola Mucci ◽  
Massimo Bracci ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Shift Work ◽  
Healthcare Workers ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Model Assessment ◽  
Homeostasis Model Assessment ◽  
Significant Positive Association ◽  
Cross Sectional ◽  
Shift Workers

Background and objectives: Evidence shows that shift work may be correlated with insulin resistance (IR). Therefore its estimation in clinical and prevention practice is of great significance. A cross-sectional study was performed to examine the Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) Index among healthcare shift workers (HCSW). Materials and Methods: A total of 272 healthcare workers (HCWs) were invited to participate in the study within an occupational surveillance framework, 137 were HCSW while 135 were healthcare non-shift workers (HCNSW). Fasting glucose, insulin, and HOMA-IR Index were evaluated in each participant and correlated with shift workers. Results: Indicators of glucose metabolism were significantly higher in HCSW p < 0.001, and logistic regression analysis confirmed a significant positive association between increased values of HOMA-IR Index and shift workers (p < 0.05). Conclusions: Shift work could be a risk factor in developing insulin resistance and metabolic syndrome.

scholarly journals A Cross-sectional study among Hospital Employees- Metabolic Syndrome and Shift Work

2021 ◽  
Vol 10 (2) ◽  
pp. 258
Author(s):  
Santhosh E Kumar ◽  
Antonisamy B ◽  
Henry Kirupakaran ◽  
Reginald G Alex
Keyword(s):  
Metabolic Syndrome ◽  
Shift Work ◽  
Multivariable Analysis ◽  
Sample Size Calculation ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Shift Workers ◽  
Hospital Employees ◽  
The Impact

Introduction: Shift workers and metabolic syndrome are on the rise in developing nations. The link between Metabolic syndrome and shiftwork is not clear. This study aims to measure the prevalence of metabolic syndrome among shift workers and daytime workers and to assess the association between metabolic syndrome and shift work. Methods: Cross- sectional study was done in a South Indian hospital. Participants were selected via systematic random sampling between the age group of 25 -50 years. There were two study groups – day and shift workers. Sample size calculation was done with an alpha error of 0.05 and power of 80% to detect a 12.5% difference for metabolic syndrome prevalence between the two groups. Outcomes studied include the prevalence of metabolic syndrome and odds of developing metabolic syndrome among shift workers. The Chi-square test and independent t-test were the tests of significance used. The impact of relevant parameters on metabolic syndrome was assessed using univariate and multivariable analysis. Results: Eighty employees were studied in each group. At baseline, differences include; daytime workers were older in age, had a better quality of sleep, were less active physically, and consisted of more vegetarians. The prevalence of metabolic syndrome prevalence was thirty-three percent among the participants. The odds ratio (adjusted for relevant confounders) for shift workers to develop metabolic syndrome was 0.55 (95% CI 0.24 -1.29). Conclusion: Metabolic syndrome was diagnosed in a third of the hospital employees studied. There was no statistical difference between shift and daytime workers for the prevalence of metabolic syndrome. Increased awareness, screening, and preventive measures of the disease are recommended.Keywords: daytime, hospital, metabolic syndrome, shift work, sleep

scholarly journals Serum Vitamin D3 Levels in Chronic Lymphocytic Leukemia and Its Relevance with Clinical Prognostic Factors

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mehdi Dehghani ◽  
Anush Khajeh ◽  
Reza Vojdani ◽  
Mozhdeh Sanei ◽  
Pedram Keshavarz ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Chronic Lymphocytic Leukemia ◽  
Vitamin D3 ◽  
Normal Population ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Lymphocytic Leukemia ◽  
Control Group ◽  
Cross Sectional

Background: Studies conducted in recent years have proposed a protective effect of vitamin D3 (VitD3) against various types of cancers. Thus, in this research, we investigated the serum levels of VitD3and its relation with prognostic clinical factors in chronic lymphocytic leukemia (CLL). Method: In this cross-sectional study, 86 CLL patients were investigated for a one-year period and evaluated for the relationship between Vit D3serum levels, Rai stages, age, gender, and pathological factors. A control group was added to the study in order to compare the VitD3 levels of CLL patients with that of the normal population. Results: The mean serum VitD3level in CLL patients was 29.76 ± 18.75 ng/ml, and most of the patients were in stage I and II. There was no significant association between age, sex, and Rai stages of CLL with VitD3 level. Except for splenomegaly (P < 0.001), the leukemia-related phenotypes, complications, and prognostic factors had no meaningful association with VitD3 (P > 0.05) level. VitD3 serum level was meaningfully different between case and control groups (P < 0.001). Conclusion: In the current research, there was no significant relationship between VitD3serum levels and investigated variables, except splenomegaly; these findings are in concordance with other studies.

scholarly journals Association between shift work and obesity in a large sample of Iranian steel industry workers

2019 ◽  
Vol 70 (3) ◽  
pp. 194-200
Author(s):  
Najmeh Rabanipour ◽  
Hamidreza Roohafza ◽  
Awat Feizi ◽  
Shahnaz Amani Tirani ◽  
Nizal Sarrafzadegan
Keyword(s):  
Shift Work ◽  
Abdominal Obesity ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Overweight And Obesity ◽  
Binary Logistic Regression Analysis ◽  
Cluster Sampling ◽  
Cross Sectional ◽  
Shift Workers ◽  
Large Sample

AbstractObesity is associated with several chronic diseases, and previous research suggests that shift work could be associated with the risk of overweight and obesity, but the results remain inconclusive. Furthermore, only a few studies report related findings for industrial workforce with high job-related stress. The aim of this cross-sectional study was to see if such association exists in a large sample of 3063 industrial workers in a developing country. The sample was selected among 16,000 steel company workers through multistage cluster sampling. We took anthropometric measurements, including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR). Information about potential confounders was collected with a self-administered questionnaire. The association between shift work and both general and abdominal obesity was established with multinomial and binary logistic regression analysis. The study sample consisted of 1683 (54.9 %) rotational shift workers and 1380 (45.1 %) day workers. Shift work was significantly associated with higher risk of overweight after adjusting for the impacts of potential confounders (OR=1.2; 95 % CI:1.04–1.4) but not with abdominal obesity. This study established that shift work was an independent risk factor for overweight in industrial shift workers. Modification of working schedules is recommended, particularly for prolonged, continuous shift work.

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