611 Sleep Disorders in a Longitudinal Community Cohort of Children with Down Syndrome

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A240-A240
Author(s):  
Nisha Patel ◽  
Timothy Morgenthaler ◽  
Julie Baughn
Keyword(s):  
Down Syndrome ◽  
Sleep Disorders ◽  
Screening Tools ◽  
Treatment Needs ◽  
Cross Sectional Survey ◽  
Periodic Limb Movement Disorder ◽  
Cross Sectional ◽  
Children With Down Syndrome ◽  
Obstructive Sleep ◽  
Respiratory Sleep Disorders

Abstract Introduction Obstructive sleep apnea (OSA) affects 50–79% of children with Down Syndrome (CDS) prompting the development of guidelines to increase early detection of OSA. Cross-sectional survey based data shows that CDS have higher rates of bedtime resistance, sleep anxiety, night waking and parasomnias, which are also under-recognized. However, due to increased survival of CDS it may be that OSA treated in childhood returns or worsens, or that CDS may develop other sleep disorders as their life experience and exposure to comorbidities expands. Little is known about sleep disorders across the life span of CDS and screening guidelines leave a gap beyond early childhood. We determined to enhance understanding of respiratory and non-respiratory sleep disorders in a community population of CDS. Methods A retrospective population based observational study of CDS born between 1995–2011 was performed using the Rochester Epidemiology Project database. Medical records from all encounters through July 2020 were reviewed to identify sleep disorders. Sleep diagnoses, sleep test results, and treatments aimed at sleep disorders were recorded. Results 94 CDS were identified with 85 providing consent for research. 54 out of 85 individuals were diagnosed with OSA with 26 diagnosed prior to age 4 and 25 undergoing polysomnography prior to treatment. 26 individuals underwent polysomnography following surgery of which 16 continued to have clinically significant OSA requiring further treatment with secondary surgery, CPAP or anti-inflammatory therapy. Other sleep disorders observed included insomnia (n=16), restless leg syndrome (n=7), periodic limb movement disorder (n=10), idiopathic hypersomnia (n=1), nightmares (n=1), nocturnal enuresis (n=1), bruxism (n=1) and delayed sleep phase disorder (n=1). Most non-OSA sleep disorders were diagnosed during OSA evaluation by sleep medicine providers. However, many children were on melatonin without a formal sleep disorder diagnosis. Conclusion Both OSA and other sleep disorders remain under-diagnosed in CDS. This may be due to lack of validated screening tools that can be administered at the primary care level. Screening recommendations should consider the longitudinal nature of OSA in CDS and the presence of non-respiratory sleep disorders. Adenotonsillectomy is not as effective in CDS and postsurgical polysomnography is warranted along with long term follow-up to assess for further treatment needs. Support (if any):

scholarly journals Down Syndrome Children, Malocclusion Characteristics and the Need for Orthodontic Treatment Needs (IOTN): A Cross-Sectional Study

Children ◽  
2021 ◽  
Vol 8 (10) ◽  
pp. 888
Author(s):  
Huda Alkawari
Keyword(s):  
Down Syndrome ◽  
Orthodontic Treatment ◽  
Dental Health ◽  
Cross Sectional Study ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Treatment Needs ◽  
Special Schools ◽  
Cross Sectional ◽  
Children With Down Syndrome

The purpose of the present study was to assess the characteristics of malocclusion and determine the orthodontic treatment needs of a group of children with Down syndrome. The study group comprised 23 children aged 10–14 years with Down syndrome who were attending special schools. A clinical examination was performed to measure several parameters that assessed malocclusion as well as classifications based on the Index of Orthodontic Treatment Need (IOTN-DC). When the dental health component (DHC) of the IOTN-DC was considered, results showed that a high percentage of children involved in the current study needed orthodontic treatment (81.9%). Moreover, 59.1% showed Angle’s class-III malocclusion compared to 36.4% who showed class I. However, the differences between the IOTN-DC values for the boys and girls were not statistically significant (p > 0.05). The present study has concluded that a higher percentage of children, suffering from Down syndrome, had very severe malocclusion; therefore, treatment can be considered mandatory. Similarly, more than three-fourths of the children with Down syndrome had visited a dental clinic at least once during their life. However, 30.4% of the children’s mothers have mentioned that they had not visited any orthodontic clinic. Therefore, there is a need to develop awareness and knowledge among the parents of children suffering from Down syndrome.

scholarly journals Prevalence of sleep disorders among medical students of Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia

2021 ◽  
Vol 9 (s1) ◽  
Author(s):  
Reda Abdelmoaty Goweda ◽  
Abdurahman Hassan-Hussein ◽  
Mohammed Ali Alqahtani ◽  
Murad Mohammed Janaini ◽  
Adi Hatim Alzahrani ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Medical Students ◽  
Sleep Disorders ◽  
Sleep Disorder ◽  
Demographic Data ◽  
Medical Problem ◽  
Periodic Limb Movement Disorder ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Second Year

Background: Sleep disorders are a common medical problem and can affect health and quality of life. There are multiple types of sleep disorders such as obstructive sleep apnea, insomnia, narcolepsy, restless legs/periodic limb movement disorder, circadian rhythm disorders, sleepwalking and nightmares. Medical students appear to be more liable to develop sleep disorders due to their high academic load.Design and Methods: This study seeks to estimate the prevalence of sleep disorders among Umm Al-Qura University medical students and associated risk factors. This cross-sectional study was conducted at the Faculty of Medicine of Umm Al-Qura University in Makkah, Saudi Arabia. A self administrated questionnaire was used to collect the data including socio-demographic data and sleep-50 questionnaire. Four hundred and thirty-eight (438) medical students from the second year to the sixth year were recruited to the study.Results: Three hundred and twenty-three participants (73.8%) complained of at least one sleep disorder. The most prevalent sleep disorder among students was narcolepsy at 226 (51.6%). Female students, second year students and students spending significant time watching television or on smartphones were more affected than others with p values of 0.001, 0.005, and 0.004, respectively.Conclusions: Sleep disorders are common among medical students. It is essential to detect and address them before their condition deteriorates.

A Community Cross-Sectional Survey of Medical Problems in 440 Children with Down Syndrome in New York State

2014 ◽  
Vol 164 (4) ◽  
pp. 871-875 ◽  
Author(s):  
Nancy J. Roizen ◽  
Caroline I. Magyar ◽  
Emily S. Kuschner ◽  
Steven B. Sulkes ◽  
Charlotte Druschel ◽  
...  
Keyword(s):  
New York ◽  
Down Syndrome ◽  
New York State ◽  
Cross Sectional Survey ◽  
Medical Problems ◽  
Cross Sectional ◽  
York State ◽  
Children With Down Syndrome

scholarly journals The Association between Difficulties with Speech Fluency and Language Skills in a National Age Cohort of Children with Down Syndrome

2021 ◽  
Vol 11 (6) ◽  
pp. 704
Author(s):  
Kari-Anne B. Næss ◽  
Egil Nygaard ◽  
Hilde Hofslundsengen ◽  
J. Scott Yaruss
Keyword(s):  
Down Syndrome ◽  
Language Skills ◽  
Typically Developing ◽  
Typically Developing Children ◽  
Cross Sectional ◽  
Exact Test ◽  
Children With Down Syndrome ◽  
Speech Fluency ◽  
Age Cohort ◽  
Student’S T

The present study (a) addressed difficulties in speech fluency in children with Down syndrome and typically developing children at a similar non-verbal level and (b) examined the association between difficulties with speech fluency and language skills in children with Down syndrome. Data from a cross-sectional parent survey that included questions about children’s difficulties with speech fluency, as well as clinical tests from a national age cohort of 43 six-year-olds with Down syndrome and 57 young typically developing children, were collected. Fisher’s exact test, Student’s t-test, linear regression, and density ellipse scatter plots were used for analysis. There was a significantly higher occurrence of parent-reported difficulties with speech fluency in the children with Down syndrome. Higher language scores were significantly associated with a lower degree of difficulties; this association was strongest for vocabulary and phonological skills. Although difficulties with speech fluency were not reported for all children with Down syndrome, a substantially higher occurrence of such difficulties was reported compared to that for typically developing children. The significant association between difficulties with speech fluency and the level of language functioning suggests that speech fluency and language skills should be taken into consideration when planning treatment for children with Down syndrome.

Sleep Positions in Children with Down Syndrome and Obstructive Sleep Apnea

2021 ◽  
Author(s):  
Jonathan D. Santoro ◽  
Justin Del Rosario ◽  
Beth Osterbauer ◽  
Emily S. Gillett ◽  
Debra M. Don
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Children With Down Syndrome ◽  
Obstructive Sleep

scholarly journals Family Variables and Quality of Life in Children with Down Syndrome: A Scoping Review

2021 ◽  
Vol 18 (2) ◽  
pp. 419
Author(s):  
Anna Lee ◽  
Kathleen Knafl ◽  
Marcia Van Riper
Keyword(s):  
Quality Of Life ◽  
Down Syndrome ◽  
Scoping Review ◽  
Personal Development ◽  
Well Being ◽  
Future Research ◽  
Cross Sectional ◽  
Children With Down Syndrome ◽  
Family Variables

The purpose of this scoping review was to identify the family and child quality of life variables that have been studied in relation to one another in children with Down syndrome, the frequency with which different relationships have been studied, and the extent to which family variables were the focus of the research aims. A literature search was conducted to find studies published between January 2007 and June 2018. The initial search yielded 2314 studies; of these, 43 were selected for a final review. Researchers most often addressed family resources and family problem-solving and coping concerning child personal development and physical well-being. Little attention to child emotional well-being was observed, with none considering family appraisal of child emotional well-being. The relationship between family variables and child QoL rarely was the primary focus of the study. Methodologically, most reviewed studies used cross-sectional designs, were conducted in North America and based on maternal report. From future research considering the issues found in this review, healthcare providers can obtain an in-depth understanding of relationships between children and family variables.

scholarly journals Uncovering Common Sleep Disorders and Their Impacts on Occupational Performance

2017 ◽  
Vol 65 (5) ◽  
pp. 232-232
Author(s):  
Sylvia R. Judd
Keyword(s):  
Sleep Disorders ◽  
Hormonal Regulation ◽  
The Body ◽  
Screening Tools ◽  
Occupational Performance ◽  
Obstructive Sleep ◽  
Occupational Health Nurse ◽  
Inadequate Sleep ◽  
Simple Screening ◽  
Healthy Immune System

Sleep is an active process; the body undergoes restoration and regeneration. Adequate sleep is essential to health and cognitive function. Sleep is critical for cell repair, a healthy immune system, and hormonal regulation, and aids in the process of learning, memory, and emotion. Inadequate sleep can lead to multiple chronic health and mental conditions over time. The occupational health nurse can be instrumental in screening for two of the most common sleep disorders, insomnia and obstructive sleep apnea, by asking workers key questions and using simple screening tools.

scholarly journals 0771 Severe Obstructive Sleep Apnea In Children With Down Syndrome

SLEEP ◽  
2018 ◽  
Vol 41 (suppl_1) ◽  
pp. A287-A287
Author(s):  
J N Mian ◽  
B Gunaratnam ◽  
E Senthilvel
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Severe Obstructive Sleep Apnea ◽  
Children With Down Syndrome ◽  
Obstructive Sleep
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