On the Reparative Process in Human Tendons after Subcutaneous Division for the Cure of Deformities; with an account of the appearances presented in fifteen post-mortem examinations in the human subject; also a series of experiments on rabbits, and a resumé of the English and foreign literature of the subject

1861 ◽  
Vol 41 (81) ◽  
pp. 237-238
Author(s):  
William Adams
Author(s):  
Svitlana Lobchenko ◽  
Tetiana Husar ◽  
Viktor Lobchenko

The results of studies of the viability of spermatozoa with different incubation time at different concentrations and using different diluents are highlighted in the article. (Un) concentrated spermatozoa were diluented: 1) with their native plasma; 2) medium 199; 3) a mixture of equal volumes of plasma and medium 199. The experiment was designed to generate experimental samples with spermatozoa concentrations prepared according to the method, namely: 0.2; 0.1; 0.05; 0.025 billion / ml. The sperm was evaluated after 2, 4, 6 and 8 hours. The perspective of such a study is significant and makes it possible to research various aspects of the subject in a wide range. In this regard, a series of experiments were conducted in this area. The data obtained are statistically processed and allow us to highlight the results that relate to each stage of the study. In particular, in this article it was found out some regularities between the viability of sperm, the type of diluent and the rate of rarefaction, as evidenced by the data presented in the tables. As a result of sperm incubation, the viability of spermatozoa remains at least the highest trend when sperm are diluted to a concentration of 0.1 billion / ml, regardless of the type of diluent used. To maintain the viability of sperm using this concentration of medium 199 is not better than its native plasma, and its mixture with an equal volume of plasma through any length of time incubation of such sperm. Most often it is at this concentration of sperm that their viability is characterized by the lowest coefficient of variation, regardless of the type of diluent used, which may indicate the greatest stability of the result under these conditions. The viability of spermatozoa with a concentration of 0.1 billion / ml is statistically significantly reduced only after 6 or even 8 hours of incubation. If the sperm are incubated for only 2 hours, regardless of the type of diluent used, the sperm concentrations tested do not affect the viability of the sperm. Key words: boar, spermatozoa, sperm plasma, concentration, incubation, medium 199, activity, viability, rarefaction.


2021 ◽  
pp. 095269512098224
Author(s):  
Chakravarthi Ram-Prasad

The Caraka Saṃhitā (ca. first century BCE–third century CE), the first classical Indian medical compendium, covers a wide variety of pharmacological and therapeutic treatment, while also sketching out a philosophical anthropology of the human subject who is the patient of the physicians for whom this text was composed. In this article, I outline some of the relevant aspects of this anthropology – in particular, its understanding of ‘mind’ and other elements that constitute the subject – before exploring two ways in which it approaches ‘psychiatric’ disorder: one as ‘mental illness’ ( mānasa-roga), the other as ‘madness’ ( unmāda). I focus on two aspects of this approach. One concerns the moral relationship between the virtuous and the well life, or the moral and the medical dimensions of a patient’s subjectivity. The other is about the phenomenological relationship between the patient and the ecology within which the patient’s disturbance occurs. The aetiology of and responses to such disturbances helps us think more carefully about the very contours of subjectivity, about who we are and how we should understand ourselves. I locate this interpretation within a larger programme on the interpretation of the whole human being, which I have elsewhere called ‘ecological phenomenology’.


1881 ◽  
Vol 32 (212-215) ◽  
pp. 407-408

During the progress of the investigations which I have from time to time had the honour of bringing under the notice of the Royal Society, I have again and again noticed the apparent disappearance of gases inclosed in vessels of various materials when the disappearance could not be accounted for upon the assumption of ordinary leakage. After a careful examination of the subject I found that the solids absorbed or dissolved the gases, giving rise to a striking example of the fixation of a gas in a solid without chemical action. In carrying out that most troublesome investigation, the crystalline separation of carbon from its compounds, the tubes used for experiment have been in nine cases out of ten found to be empty on opening them, and in most cases a careful testing by hydraulic press showed no leakage. The gases seemed to go through the solid iron, although it was 2 inches thick. A series of experiments with various linings were tried. The tube was electro-plated with copper, silver, and gold, but with no greater success. Siliceous linings were tried fusible enamels and glass—but still the' tubes refused to hold the contents. Out of thirty-four experiments made since my last results were published, only four contained any liquid or condensed gaseous matter after the furnacing. I became convinced that the solid matter at the very high pressure and temperature used must be pervious to gases.


1889 ◽  
Vol 180 ◽  
pp. 331-354

The following paper contains the record of an investigation into the degenerations which follow lesions of the gyrus marginalis and gyrus fornicatus in Monkeys. The work has been carried on under my direction by Mr. France, with the aid of a grant from the Government Grant Fund, and represents part of a long investigation into the degenerations which follow artificially produced cerebral lesions, the material for which has been furnished by cases operated upon in conjunction respectively with Professor V. Horsley and Dr. Sanger Brown. These cases and the physiological results of the operations have already been published in the ‘Philosophical Transactions.’ The experiments here dealt with, twelve in number, comprise only the lesions of the gyrus marginalis and gyrus fornicatus, and, with one exception (case 12), are taken from the series of experiments performed in conjunction with Mr. Horsley. Of the twelve cases, six were of removal, or attempted removal, of the gyrus marginalis, and six of removal, or attempted removal, of the gyrus fornicatus. But in only one or two instances was the lesion, as determined by post-mortem examination, exactly limited to the convolution which it was attempted to remove, for in most cases the adjacent gyrus was to a certain extent involved in the injury. This was especially the case when removal of the gyrus fornicatus had been attempted, on account of its deep situation, and the difficulty of getting at it without some manipulation of the superjacent gyrus. Nevertheless, the removal of one or the other gyrus was sufficiently complete in all the cases here selected to produce characteristic symptoms and characteristic descending degenerations.


1950 ◽  
Vol 2 (2) ◽  
pp. 76-87 ◽  
Author(s):  
J. W. Whitfield

The experiment was designed to throw some light on the statistical problems in the analysis of questionnaire data. Previous work (unpublished) suggested that a simple choice response was partially determined by previous responses; and also that the nature of the determination was changed with changing length of series. A “null” experiment was devised in the form of a questionnaire without any questions, and the distribution of responses was studied with respect to the problems formulated. The observations are discussed in three sections. In the statistical discussion an alternative meaning to overall association or dissociation is advanced. This: relates association or dissociation to human behaviour in the serial response situation, rather than to qualities of the questionnaire. It is further suggested that association between specific, questions should be tested against the association in the whole questionnaire, and an appropriate treatment is indicated. The observations depart from statistical randomness in certain ways. Answers made up almost entirely of one form of response are given less often than would be expected. Long sequences of the same type of response are relatively infrequent, and sequences of alternation of response are also rare. As the material is “null” it implies that the human concept of randomness differs from the statistical concept. An attempt is made to define the human concept of randomness. It appears that a series of responses which has a pattern, or for which the subject can postulate a simple “cause” will not be accepted as random by the human subject. This raises problems of a perceptual and cognitive nature. It also has a bearing on the design of questionnaires. or experiments involving serial responses.


Author(s):  
Heron Teixeira

Introduction: Estimating the time of death is an important task in day-to-day forensic work and many factors for its designation are understood, one of which is rigor mortis. They can be altered by extrinsic and intrinsic factors, such as temperature location, humidity, heat, age, sex, length and body weight, and can be used as a parameter for approximate identification of the time of death. Objective: To carry out a brief review on the topic in order to promote a better understanding of the subject addressed and fully understand its physiology. Materials and Methods: Pubmed, Scielo and Medline databases were searched without date restrictions for articles published in English and Portuguese using the descriptors rigor mortis, autolysis and changes after death. Results: The theme presents consolidated researches regarding its natural course, being an important tool to estimate the time of death along other signs that appear after death, as well as to estimate some causes of death. Conclusion: Understanding the development of rigor mortis, helps to identify and distinguish processes that may have led to death and the post-mortem time.


2021 ◽  
Vol 15 (3) ◽  
pp. 386-410
Author(s):  
Andrew Lapworth

The recent ‘nonhuman turn’ in the theoretical humanities and social sciences has highlighted the need to develop more ontological modes of theorising the ethical ‘responsibility’ of the human in its relational encounters with nonhuman bodies and materialities. However, there is a lingering sense in this literature that such an ethics remains centred on a transcendent subject that would pre-exist the encounters on which it is called to respond. In this essay, I explore how Gilles Deleuze's philosophy offers potential opening for a more ontogenetic thinking of a ‘nonhuman ethics’. Specifically, I focus on how his theory of ‘individuation’ – conceived as a creative event of emergence in response to immanent ontological problems – informs his rethinking of ethics beyond the subject, opening thought to nonhuman forces and relations. I argue that if cinema becomes a focus of Deleuze's ethical discussions in his later work it is because the images and signs it produces are expressive of these nonhuman forces and processes of individuation, generating modes of perception and duration without ontological mooring in the human subject. Through a discussion of Verena Paravel and Lucien Castaing-Taylor's experimental film –  Leviathan (2012)  – I explore how the cinematic encounter dramatises different ethical worlds in which a multiplicity of nonhuman ‘points of view’ coexist without being reduced to a hierarchical or orienting centre that would unify and identify them. To conclude, I suggest that it is through the lens of an ethics of individuation that we can grasp the different sense of ‘responsibility’ alive in Deleuze's philosophy, one oriented not to the terms of the already-existing but rather to the nonhuman potential of what might yet come into being.


1901 ◽  
Vol 47 (199) ◽  
pp. 729-737 ◽  
Author(s):  
Joseph Shaw Bolton

This demonstration was a further report on the subject laid before the Association at the meeting at Claybury in February last, viz., the morbid changes occurring in the brain and other intra-cranial contents in amentia and dementia. In a paper read before the Royal Society in the spring of 1900, and subsequently published in the Philosophical Transactions, it was stated, as the result of a systematic micrometric examination of the visuo-sensory (primary visual) and visuo-psychic (lower associational) regions of the cerebral cortex, that the depth of the pyramidal layer of nerve-cells varies with the amentia or dementia existing in the patient. At the meeting of the Association referred to it was further shown, from an analysis, clinical and pathological, of 121 cases of insanity which appeared consecutively in the post-mortem room at Claybury, that the morbid conditions inside the skull-cap in insanity, viz., abnormalities in the dura mater, the pia arachnoid, the ependyma and intra-cranial fluid, etc., are the accompaniments of and vary in degree with dementia alone, and are independent of the duration of the mental disease. Since that date the pre-frontal (higher associational) region has been systematically examined in nineteen cases, viz., normal persons and normal aments (infants), and cases of amentia, of chronic and recurrent insanity without appreciable dementia, and of dementia, and the results obtained form the subject of the present demonstration. A paper on the whole subject will shortly be published in the Archives of the Claybury Laboratory.


1963 ◽  
Vol 9 (1) ◽  
pp. 65-73 ◽  
Author(s):  
N. N. LeBlanc ◽  
A. J. Musgrave

Since 1850, aphids have been regarded as harboring, in mycetomes, supposedly beneficial microorganisms which have, however, been the subject of some controversy. In the present study of the aphids Aphis jabae and Macrosiphum pisi, mycetomes were identified in histological sections; but it proved impossible to isolate or culture any mycetomal microorganisms. Moreover, in a series of experiments in which great attention was paid to refined aseptic techniques no microorganisms could be isolated from the general body cavities or alimentary tracts of the aphids, though simultaneous attempts to isolate microorganisms from weevils were successful.


1834 ◽  
Vol 124 ◽  
pp. 583-591 ◽  

The path of a luminous or an illuminated point in rapid motion, it is well known, appears as a continuous line, in consequence of the after duration of the visual im­pression. There is nothing, however, in the appearance of such a line by which the eye can determine either the direction or the velocity of the motion which generates it. It occurred to me some years since, that if the motion which described the line in these cases were to be compounded with another motion, the direction and velocity of which were known, it would be easy, from an inspection of the resultant straight or curved line, to determine the velocity and direction of the former. Following up this idea, I made a series of experiments relating to the oscillatory motions of sono­rous bodies, too numerous, and not sufficiently connected with the subject of the pre­sent communication, to be detailed in this place. The satisfactory results thus ob­tained made me desirous to ascertain whether, by similar means, some information might not be gained respecting the direction and velocity of the electric spark : the method by which I then proposed to effect this purpose was first announced in a lec­ture delivered by Dr. Faraday at the Royal Institution in June, 1830. My attention was again drawn to the subject at the commencement of last year, and I attempted to realize the idea in the following manner. Fig. 1 represents the apparatus employed, which was screwed at a to the spindle of a whirling machine, so that a rapid rotatory motion might be given to it. The upper and lower parts, which were all of brass except the wooden disc b c , were insulated from each other by a stout glass rod d e ; a slip of tinfoil connected the ball h with a , and the upper ball g was capable of adjustment to various distances from the lower one h . When the ball f was placed within striking distance of the prime conductor of an electric machine, a spark passed between them, and also between the balls g and h , which could be separated to the distance of four inches, so as to exhibit a spark of that length. It is obvious, that if the angular motion of the balls were in any sensible proportion to the velocity of electricity, there would be a deviation between the upper and lower terminations of the line. The instrument revolving from left to right, if the motion of the spark be downwards, the deflection of the line should be as in fig. 2; and if its motion be upwards, it should be deflected as in fig. 3.


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