In East Asian American adults, does routine screening with EGD reduce morbidity and mortality from gastric cancer?

2017 ◽  
Vol 20 (8) ◽  
pp. 7
Author(s):  
Lee M. Jordan ◽  
Kristen Reineke-Piper
2017 ◽  
Vol 3 ◽  
pp. 215-221 ◽  
Author(s):  
Maciej Ciesielski ◽  
Wiesław J. Kruszewski ◽  
Jakub Walczak ◽  
Mariusz Szajewski ◽  
Jarosław Szefel ◽  
...  

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1846-1860
Author(s):  
Tahmina A ◽  
Kevin F ◽  
Das S ◽  
Habib N ◽  
Rashid M

COVID -19 pandemic is creating an uncertainty about the demographic trends of morbidity and mortality rates across countries worldwide. Hence, this study is aimed to characterize the gender and age distribution of morbidity and mortality from COVID-19 across populations. This cross-sectional study uses aggregate data on COVID-19 cases and deaths by gender and age. Considering gender-based morbidity, men diagnosed with COVID-19 substantially outnumber infected women with statistically significant findings (*p=<0.05, □ RR>2) in Asian, American, and African countries, whereas women diagnosed higher morbidity rate in European countries. However, gender-based fatality showed higher among men in most of the analyzed countries of all those continents except Australia where female fatality was higher. This study revealed 50 years old were mostly associated with the infection and death in all continents except Australia, showing more morbidity above 20 years of age, whereas, fatality rate was more in the above 80 years group. The study concludes that, across countries, COVID-19 morbidity and fatality rate is age specific rather than gender specific. Infection rates showed rising steeply with age; nevertheless, children do not stand on equal footing when COVID-19 crisis is transforming their day-to-day lives.


2019 ◽  
Vol 13 (1) ◽  
pp. 6-11 ◽  
Author(s):  
Idrees Suliman ◽  
John Guirguis ◽  
Iryna Chyshkevych ◽  
Nemer F. Dabage

Colorectal cancer is a leading cause of morbidity and mortality worldwide. As such, there are recognized guidelines in the screening of this preventable cancer. There are differences in opinion regarding screening recommendations between the European and United States Cancer Prevention Societies. Screening colonoscopy is an option for routine screening for colorectal cancer in asymptomatic adults. It is a day procedure that is conducted both in hospital and specialized outpatient endoscopy suites. Serious harm is in the region of 3 per 1,000 examinations [Am J Gastroenterol. 2016 Aug; 111(8): 1092–101]. Splenic injury is a rare complication of colonoscopy whose frequency is unclear. Conservative management of splenic injury is desirable in order to preserve immunocompetence. We present a case in which a previously healthy 59-year-old female developed a splenic injury and later pleural effusion after screening colonoscopy.


Cancers ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 725 ◽  
Author(s):  
Tegshee Tserentogtokh ◽  
Boldbaatar Gantuya ◽  
Phawinee Subsomwong ◽  
Khasag Oyuntsetseg ◽  
Dashdorj Bolor ◽  
...  

Helicobacter pylori infection possessing East-Asian-type CagA is associated with carcinogenesis. Mongolia has the highest mortality rate from gastric cancer. Therefore, we evaluated the CagA status in the Mongolian population. High risk and gastric cancer patients were determined using endoscopy and histological examination. H. pylori strains were isolated from different locations in Mongolia. The CagA subtypes (East-Asian-type or Western-type, based on sequencing of Glu-Pro-Ile-Tyr-Ala (EPIYA) segments) and vacA genotypes (s and m regions) were determined using PCR-based sequencing and PCR, respectively. In total, 368 patients were examined (341 gastritis, 10 peptic ulcer, and 17 gastric cancer). Sixty-two (16.8%) strains were cagA-negative and 306 (83.1%) were cagA-positive (293 Western-type, 12 East-Asian-type, and one hybrid type). All cagA-negative strains were isolated from gastritis patients. In the gastritis group, 78.6% (268/341) had Western-type CagA, 2.9% (10/341) had East-Asian-type, and 18.2% (61/341) were cagA-negative. However, all H. pylori from gastric cancer patients possessed Western-type CagA. Histological analyses showed that East-Asian-type CagA was the most virulent strains, followed by Western-type and cagA-negative strains. This finding agreed with the current consensus. CagA-positive strains were the most virulent type. However, the fact that different CagA types can explain the high incidence of gastric cancer might be inapplicable in Mongolia.


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