IV. Spirometric studies of Yemenite and Kurdish Jews in Israel

Measurements have been made of forced expiratory volume (f.e.v.) and forced vital capacity (f.v.c.) in two groups of rural Israeli Jews aged 20 to 30, born in the Yemen and in Kurdistan. The Jews from Kurdistan had a significantly higher f.e.v. and f.v.c. than the Jews from the Yemen, but there was no difference in the f.e.v. % ratio. These differences were not accounted for by differences between the groups in age, nor entirely by morphological differences. The pattern of correlations with anthropometric variables suggested that in the Jews from the Yemen the lung function values were related to linearity rather than to body bulk, while in the Jews from Kurdistan they were better correlated with overall size and mass of the body. f.e.v. and f.v.c. were elevated in smokers compared to non-smokers, possibly owing to an increased respiratory effort to cope with a reduction in the f.e.v. % ratio.

Respiration ◽  
2020 ◽  
pp. 1-8
Author(s):  
Pierre-Henri Aussedat ◽  
Nader Chebib ◽  
Kais Ahmad ◽  
Jean-Charles Glerant ◽  
Gabrielle Drevet ◽  
...  

<b><i>Background:</i></b> Video-assisted surgical lung biopsy (SLB) is performed in 10–30% of cases to establish the diagnosis of idiopathic pulmonary fibrosis (IPF). <b><i>Objectives:</i></b> The aim of the study was to analyze the impact of SLB on lung function in patients eventually diagnosed with IPF. <b><i>Methods:</i></b> This is an observational, retrospective, monocentric study of all consecutive patients eventually diagnosed with IPF in multidisciplinary discussion who underwent SLB over 10 years in a specialized center. The primary end point was the variation in forced vital capacity (FVC) before and after the SLB. The secondary end points were the variations in forced expiratory volume in one second (FEV1), total lung capacity (TLC), carbon monoxide diffusion capacity (DLCO), and morbidity and mortality associated with the SLB. <b><i>Results:</i></b> In 118 patients who underwent SLB and were diagnosed with IPF, a relative decrease in FVC of 4.8% (<i>p</i> &#x3c; 0.001) was found between measurements performed before and after the procedure. The mean FVC decrease was 156 ± 386 mL in an average period of 185 days, representing an annualized decline of 363 ± 764 mL/year. A significant decrease was also observed after SLB in FEV1, TLC, and DLCO. Complications within 30 days of SLB occurred in 14.4% of patients. Two patients (1.7%) died within 30 days, where one of them had poor lung function. Survival at 1 year was significantly poorer in patients with FVC &#x3c;50% at baseline. <b><i>Conclusion:</i></b> In this uncontrolled study in patients ultimately diagnosed with IPF, SLB was followed by a significant decline in FVC, which appears to be numerically greater than the average decline in the absence of treatment in the literature. <b><i>Summary at a Glance:</i></b> This study evaluated the change in lung function in 118 consecutive patients diagnosed with idiopathic pulmonary fibrosis by surgical lung biopsy. Forced vital capacity decreased by 156 ± 386 mL in a mean of 185 days between the last measurement before and first measurement after biopsy, representing an annualized decline of 363 ± 764 mL/year.


e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Maniata F. Bata ◽  
Maarthen C.P. Wongkar ◽  
Bisuk P. Sedli

Abstract: Smoking is one of the factors causing decline of lung function characterized by impairment of Forced Expiratory Volume in 1 second (FEV1), Forced Vital Capacity (FVC), and FEV1/FVC. This study was aimed to obtain the differences in FEV1 between smokers and non smokers, among smokers based on duration of smoking, and among smokers based on the number of cigarettes per day in medical students of University of Sam Ratulangi Manado. This was an observational analytic study. Data were analyzed by using the independent T test and the ANOVA with the F Test. Subjects were 40 males, consisted of 20 smokers and 20 non-smokers. Six smokers had smoked for 2-5 years and 14 smokers had smoked for >5 years. Smoking less than10 cigarettes/day, 10-20 cigarettes/day, and more than 20 cigarettes/day were found in 8, 9, and 3 subjects respectively. The independent T-test showed that there was no significant difference in FEV1 between smokers and non-smokers (p=0.250). The independent T-test also showed that there was no significant difference in FEV1 between smokers of 2-5 years and smokers of more than 5 years (p=0.117). The ANOVA test showed that there was no significant difference in FEV1 between smokers of <10 cigarettes/day, 10-20 cigarettes/day, and >20 cigarettes/day (p=0.481). Conclusion: In this study there were no significant differences in FEV1 between smokers and non smokers, among smokers based on duration of smoking, and among smokers based on the number of cigarettes per day.Keywords: smoker, non smoker, FEV1, duration of smoking, number of cigarette Abstrak: Merokok adalah salah satu faktor penyebab penurunan fungsi paru yang ditandai oleh penurunan nilai volume Forced Expiratory Volume in 1 Second (FEV1), Forced Vital Capacity (FVC), dan rasio FEV1/FVC. Penelitian ini bertujuan untuk mengetahui perbedaan FEV1 antara subjek perokok dan non perokok, antar subjek perokok berdasarkan lama merokok, dan antar subjek perokok berdasarkan jumlah batang rokok yang dihisap per hari pada mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi. Jenis penelitian ialah observasional analitik dengan uji T independent dan uji ANOVA dengan uji F. Subjek penelitian ialah 40 orang laki-laki terdiri dari 20 subjek perokok dan 20 subjek non perokok. Hasil penelitian mendapatkan terdapat 6 subjek perokok yang telah merokok selama 2-5 tahun dan 14 subjek telah merokok selama >5 tahun sedangkan yang menghisap rokok <10 batang/hari, 10-20 batang/hari, dan >20 batang/hari ialah masing-masing 8 orang, 9 orang, dan 3 orang. Uji T-independent menunjukkan tidak terdapat perbedaan bermakna antara FEV1 subjek perokok dan non perokok (p=0,250). Hasil uji T independent terhadap perbedaan FEV1 subjek perokok yang telah merokok 2-5 tahun dengan yang telah merokok >5 tahun mendapatkan p=0,117. Uji ANOVA terhadap perbedaan nilai FEV1 antara subjek perokok yang menghisap rokok sebanyak <10 batang/hari, 10-20 batang/hari, dan >20 batang/hari mendapatkan p=0,481. Simpulan: Pada penelitian ini tidak terdapat perbedaan bermakna antara FEV1 subjek perokok dan non perokok, antar subjek perokok berdasarkan lama merokok, dan antar subjek perokok berdasarkan jumlah batang rokok yang dihisap per hari.Kata kunci: perokok, non perokok, FEV1, lama merokok, jumlah batang rokok


Author(s):  
Snehunsu Adhikari ◽  
Adilakshmi Perla ◽  
Suresh Babu Sayana ◽  
Mithilesh K. Tiwari ◽  
Tambi Medabala

Background: Spirometry is an essential tool to evaluate lung function of health and disease. Adaptability of lung and chest among athletes can be assessed by lung function test (LFT). The quest of our study was to evaluate the lung function (LF) of highly trained Indian female weighting athletes, and intended to appraise the adaptation of LF among trained elite athletes.Methods: Top ranked Indian female professional weightlifters (study group, n=6) were recruited for this study. Three out of the six weightlifters were from top ten world ranking of 6th, 7th and 9th. Age matched controls (control group, n=6) were selected for this study. Maximum voluntary ventilation (MVV), vital capacity (VC), forced vital capacity (FVC), percentage of forced expiratory volume in first second (FEV1%) and ratio of forced expiratory volume in first second and forced vital capacity (FEV1/FVC%) have been evaluated as per the ATS/ERS guidelines.Results: Statistically higher significant values of VC and FVC were noted in study group, where as other values (MVV, FEV1% and FEV1/FVC%) found no significant difference between two groups.Conclusions: Power, strength and explosiveness of the skeletal muscles are vital domains in weightlifting sport. Weightlifting is such a sport doesn’t require much ventilatory efforts during training as well as competition. This study clueing that physiological adaptation/ improvement of the pulmonary function (PF) depends on the type of the sport being engaged by the athletes.


1986 ◽  
Vol 72 (2) ◽  
pp. 94-103
Author(s):  
Caroline S. M. Searing ◽  
D. J. Smith ◽  
R. J. Pethybridge ◽  
R. F. Goad ◽  
S. J. Legg

SummaryA four phase investigation into the effects of Royal Naval firefighting training on pulmonary function was carried out between 1979 and 1984. Phases I and II, reported elsewhere, failed to demonstrate changes in the lung function either in instructors, as measured by forced spirometry and transfer factor, over a one month period, or trainees, as measured by forced spirometry, during a one day fire-fighting course.This paper describes the results of phase III in which further lung function data was gathered from the instructors, at six monthly intervals, over two years. Multiple regression analysis of the data indicated that smoke exposure had a significant effect on the transfer factor (T1), flow at 75% of the forced vital capacity (FEF75) , and the ratio of the forced expiratory volume in one second to the forced vital capacity (FEV1/FVC%). The decrements observed were many times those predicted for normal ageing.Analysis of data collected on instructors who had left the school in the previous twelve months failed to reveal any significant improvement in these three measurements. A later follow up study conducted 3 to 5 years after instructors had left the school (Phase IV) showed significant improvements in T1 and FEF75 when related to the first readings after leaving the school.The changes observed are confounded by the high incidence of cigarette smokers amongst the instructors.


2016 ◽  
Vol 8 (1) ◽  
pp. 37 ◽  
Author(s):  
Mulyana Mulyana ◽  
Nuri Purwito Purwito Adi ◽  
Meily L Kurniawidjaja ◽  
Andi Wijaya ◽  
Irawan Yusuf

BACKGROUND: Exposure to welding fume in the workplace was associated with lung function disorders and occupational asthma. In this study, we determined lung function parameters in men workers exposed to welding fumes from heavy equipment manufacturer. This study is a preliminary study of biomonitoring program in worker exposed to welding fume as our main study. METHODS: A study with case-control design, random study, was conducted among welder (59 subjects) and non-welder (34 subjects) with more than one year experience in the same job task in a heavy equipment manufacturer. All subjects completed physical examination, informed consent, questionnaire and lung function status. Lung function status was measured by spirometer with vital capacity (VC), forced vital capacity (FCV), forced expiratory volume in one second (FEV1) and ratio of FEV1/FVC as test parameters. Linear regression model was developed to identify the risk factor of lung function parameter status using age, working period and smoking status as variables. RESULTS: This study showed that there were significant lower VC, FVC and FEV1 in welder than non-welder, but not difference in ratio of FEV1/FVC. However, there was no significant difference among welder from foundry and fabrication plan. By multivariate analysis, working period was found as a risk factor for lower parameters in lung function among welder. CONCLUSION: Lung function parameters status were significantly lower in welder than non-welder, and working period was the most important indicator for lung function status evaluation among welder. KEYWORDS: vital capacity, VC, forced vital capacity, FCV, forced expiratory volume in one second, FEV1, lung function, ratio of FEV1/FVC, working period 


2021 ◽  
Vol 3 (1) ◽  
pp. 18-19
Author(s):  
Ricardo Lemus-Rangel

<b>Background:</b> Video-assisted surgical lung biopsy (SLB) is performed in 10–30% of cases to establish the diagnosis of idiopathic pulmonary fibrosis (IPF). <b>Objectives:</b> The aim of the study was to analyze the impact of SLB on lung function in patients eventually diagnosed with IPF. <b>Methods:</b> This is an observational, retrospective, monocentric study of all consecutive patients eventually diagnosed with IPF in multidisciplinary discussion who underwent SLB over 10 years in a specialized center. The primary end point was the variation in forced vital capacity (FVC) before and after the SLB. The secondary end points were the variations in forced expiratory volume in one second (FEV<sub>1</sub>), total lung capacity (TLC), carbon monoxide diffusion capacity (DLCO), and morbidity and mortality associated with the SLB. <b>Results:</b> In 118 patients who underwent SLB and were diagnosed with IPF, a relative decrease in FVC of 4.8% (<i>p</i> &#x3c; 0.001) was found between measurements performed before and after the procedure. The mean FVC decrease was 156 ± 386 mL in an average period of 185 days, representing an annualized decline of 363 ± 764 mL/year. A significant decrease was also observed after SLB in FEV<sub>1</sub>, TLC, and DLCO. Complications within 30 days of SLB occurred in 14.4% of patients. Two patients (1.7%) died within 30 days, where one of them had poor lung function. Survival at 1 year was significantly poorer in patients with FVC &#x3c;50% at baseline. <b>Conclusion:</b> In this uncontrolled study in patients ultimately diagnosed with IPF, SLB was followed by a significant decline in FVC, which appears to be numerically greater than the average decline in the absence of treatment in the literature. Summary at a Glance: This study evaluated the change in lung function in 118 consecutive patients diagnosed with idiopathic pulmonary fibrosis by surgical lung biopsy. Forced vital capacity decreased by 156 ± 386 mL in a mean of 185 days between the last measurement before and first measurement after biopsy, representing an annualized decline of 363 ± 764 mL/year.


Author(s):  
Bhumika T. Vaishnav ◽  
Tushar V. Tonde

Background: Previous studies suggest that obese individuals are prone to pulmonary function abnormalities. The aim of this study was to evaluate pulmonary function tests in obese individuals and to relate pulmonary abnormalities if any found to lipid abnormalities and to the extent and duration of obesity.Methods: This prospective study was done on 40 obese patients attending to Dr. D. Y. Patil Hospital, Mumbai with complaints of pulmonary functions during the period from January to December 2012. Pulmonary function test was done with the help of Jaegers pneumoscreen. The percentage of body fat was determined by using triceps skin fold thickness technique by using Vernier callipers. Fasting serum samples was collected to analyses cholesterol and triglycerides.Results: Female preponderance was seen in the study (57.5%). Forced expiratory volume, forced vital capacity, maximum mid expiratory flow rate was significantly reduced and the ratio of forced expiratory volume in one second to forced vital capacity was significantly increased in individuals who had abnormal pulmonary function. Decrease in pulmonary function was noted with increased levels of cholesterol and triglyceride but the correlation was not significant.Conclusions: Obese individuals although asymptomatic have significant lung function abnormality in the form of restrictive as well as obstructive pattern. Hence, reduction in the body weight may help in reversal of the pulmonary function indices.


2020 ◽  
Vol 3 (2) ◽  
pp. 201-212
Author(s):  
Diah Astini Paramita ◽  
Andi Wardihan Wardihan ◽  
Arif Santoso

ABSTRACT This study aims to determine the correlation between exercise programs with lung function and swimming achievements of young adult athletes. Planning an exercise program by considering physiological stimulus encourages the body to adapt and improve lung function and maximize their performance. This is observational research used retrospective cohort study design. Sample in this study was selected based on the required criteria, 31 swimming athletes from the Indonesian Swimming Association of South Sulawesi and Swimming Club of Hasanuddin University, which are divided into two groups based on the presence or absence of the exercise program periodization that was implemented in the last 3 months. Data obtained through questionnaires and direct lung function examination using a spirometer. Based on the results of data analysis, it is known that there is a significant correlation between the exercise program and lung function, including Vital Capacity (VC), Force Vital Capacity (FVC) and Forced Expiratory Volume 1 second (FEV1) where the value of p <0.05. There is also a significant correlation between exercise program and swimming achievement where the value of p <0.01.


1980 ◽  
Vol 36 (4) ◽  
pp. 93-96
Author(s):  
C. P. Rodseth

The main elements of a chest assessment are outlined. Elementary measurements which should be taken by physiotherapists are described. Simple lung function tests which are within the capability of physiotherapists who are closely concerned with chest patients are explained in some detail. The tests concerned are: Peak Expiratory Flow Rate, Forced Vital Capacity, Forced Expiratory Volume in 1 sec. and the ratio Forced Expiratory Volume in 1 sec./Forced Vital Capacity as a percentage. Four of the more advanced tests and their underlying concepts which are more the domain of special pulmonary testing laboratories are briefly described.


1970 ◽  
Vol 2 ◽  
pp. 7-12 ◽  
Author(s):  
Sultana Rokeya Mannan ◽  
Noorzahan Begum ◽  
Shelina Begum ◽  
Sultana Ferdousi ◽  
Taskina Ali

The present study was carried out to observe the correlation of some lung function parameters with the endogenous plasma progesterone level during different phases of menstrual cycle. The study was conducted on 30 healthy young female volunteers with age range of 20-25 years in the department of Physiology of BSMMU, Dhaka, during July 2005- June 2006. All the subjects were studied in 3 phases of menstrual cycle for 2 consecutive cycles. FVC, FEV1 , FEV1/FVC% for assessing lung function and plasma Progesterone level during each phase of menstrual cycle were measured by a portable spirometer and by ELIZA method in auto analyzer respectively. Comparison of the values between different phases were done by paired ‘t' test considering menstrual phase data as baseline due to negligible amount of progesterone detected in this phase. Correlation of FVC , FEV1 and FEV1/FVC%with Progesterone level in each 3 phases were analyzed by Pearson's correlation- coefficient test. Plasma progesterone level was much higher during luteal phase compared to those of follicular phases of both cycles (24.54ng/ml vs1.41 ng/ml; 26.56 ng/ml vs. 1.48 ng/ml). Both FVC and FEV1 were significantly higher (p<0.001) during luteal phase than those of follicular phases in both the cycles. FVC, FEV1 and FEV1/FVC%were positively correlated with plasma progesterone level but these relationships had failed to show any statistical significance. Similar to others, this study also observed increased ventilation and high endogenous progesterone level during luteal phase. Therefore increased ventilation might be related to high progesterone level during luteal phase owing to increased inspiratory muscle endurance and bronchial relaxation effect. Key words: Plasma Progesterone; Forced Vital Capacity; Forced Expiratory Volume; Menstrual cycle. DOI:10.3329/jbsp.v2i0.976 J Bangladesh Soc Physiol. 2007 Dec;(2): 7-12.


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