scholarly journals speA and speC toxin genes among group A streptococcus isolates from school children in Chennai, India

2007 ◽  
Vol 56 (11) ◽  
pp. 1574-1575 ◽  
Author(s):  
Charmaine Lloyd ◽  
Thangam Menon
Keyword(s):  
School Children ◽  
Group A Streptococcus ◽  
Toxin Genes ◽  
Group A

scholarly journals Group A streptococcal antigen detection in school children

1998 ◽  
Vol 4 (2) ◽  
pp. 260-264
Author(s):  
H. Nsanze ◽  
K. Dawson ◽  
A. S. Ameen ◽  
N. Mustafa
Keyword(s):  
School Children ◽  
Group A Streptococcus ◽  
Positive Culture ◽  
Antigen Detection ◽  
Streptococcal Antigen ◽  
Group A ◽  
Culture Negative

The objective of the study was to determine the correlation between group A streptococcal antigen detected from throat swabs with the culture results. A total of 1457 children had two swabs taken simultaneously, and culture and antigen detection were performed. There was a good correlation between antigen detection and isolation rates. In all, 225 strains of group A streptococcus were isolated;53 [57.6%] were from the 92 children with high antigen positivity, 68 [55.7%] were from the 122 children with medium antigen positivity and 77 [25.4%] were from 303 children with low antigen positivity;only 27 [2.9%] were from the 940 children with no antigen detected. We postulate that those who are antigen-positive, culture-negative carry the organisms in their throats, but they may be missed on culture because of the small number carried

scholarly journals Asymptomatic throat carriage rate and antimicrobial resistance pattern of Streptococcus pyogenes in Nepalese school children

1970 ◽  
Vol 7 (4) ◽  
pp. 392-396 ◽  
Author(s):  
SP Dumre ◽  
K Sapkota ◽  
M Adhikari ◽  
D Acharya ◽  
M Karki ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
Streptococcus Pyogenes ◽  
School Children ◽  
Group A Streptococcus ◽  
Health Concern ◽  
Diffusion Method ◽  
Antibiotics Resistance ◽  
Carriage Rate ◽  
Significant Difference ◽  
Group A

Background: Streptococcus pyogenes or Group A streptococcus (GAS) causes several suppurative and non suppurative infections. In addition to pharyngitis and skin infections, GAS are also the causative agent of post-streptococcal infection syndromes such as acute rheumatic fever (ARF) and post-streptococcal glumerulonephritis (PSG). GAS frequently colonises in the throat of an asymptomatic person. Pharyngeal carriage rates of GAS among healthy school children vary with geographical location and seasons. Objectives: We carried out this preliminary study to determine the throat carriage rate and antimicrobial resistance trend of Streptococcus pyogenes or Group A streptococcus (GAS) among the Nepalese school children. Materials and methods: Four schools situated at different locations of Kathmandu valley were included in the study. Throat swabs from 350 students of age group 5-15 years were collected, immediately transported to the laboratory and were processed for S. pyogenes following standard microbiological procedures. Antimicrobial susceptibility testing of the isolates was performed by Kirby Bauer disc diffusion method following CLSI guidelines. Results: S. pyogenes was isolated from 10.9% (38/350) of the screened children. The GAS colonisation rate was statistically insignificant (P>0.05) with sex and age sub-groups, although the rate was slightly higher among girls and age sub-group 9-12 years. No significant difference in carrier rate was observed among different schools (P>0.05). All isolates were susceptible to azithromycin. No resistance was detected for penicillin and its derivative antibiotic ampicillin. Highest resistance rate was observed for cotrimoxazole (71.0%) followed by chloramphenicol (7.8%), ciprofl oxacin (5.2%) and erythromycin (5.2%). Conclusion: Antibiotic resistant GAS isolated from asymptomatic Nepalese school children is a public health concern. When screened and appropriately treated with antibiotics, carriers can be prevented from spreading of streptococcal infections in the school environment and the community. Preventing cross infections would ultimately reduce the incidence of life-threatening sequelae which are debilitating and difficult to treat. It is recommended to conduct regular screening and GAS surveillance in schools, and maintain rational use of antibiotics to minimise GAS carriage/infections and resistance. Key words: Streptococcus pyogenes; Antibiotics Resistance; Throat carriage; Children; Nepal. DOI: 10.3126/kumj.v7i4.2760 Kathmandu University Medical Journal (2009) Vol.7, No.4 Issue 28, 392-396

Relationship of Movements and Behaviors to Group A Streptococcus Infections in Elementary School Children

2007 ◽  
Vol 61 (3) ◽  
pp. 279-284 ◽  
Author(s):  
Tanya K. Murphy ◽  
Lisa A. Snider ◽  
P. Jane Mutch ◽  
Elaine Harden ◽  
Annette Zaytoun ◽  
...  
Keyword(s):  
Elementary School ◽  
School Children ◽  
Elementary School Children ◽  
Group A Streptococcus ◽  
Group A ◽  
And Behaviors ◽  
Relationship Of

Etiology, clinical presentation, laboratory diagnostics, pathogenesis of impetigo and treatment methods

2020 ◽  
pp. 64-70
Author(s):  
Anastasiya Laknitskaya
Keyword(s):  
Streptococcus Pyogenes ◽  
Skin Diseases ◽  
Group A Streptococcus ◽  
Antibiotic Sensitivity ◽  
Antioxidant Defense System ◽  
Laboratory Diagnostics ◽  
Treatment Methods ◽  
Group A ◽  
The Individual

Currently, one of the priority medical and social problems is the optimization of treatment methods for pyoderma associated with Streptococcus pyogenes — group A streptococcus (GAS). To date, the proportion of pyoderma, the etiological factor of which is Streptococcus pyogenes, is about 6 % of all skin diseases and is in the range from 17.9 to 43.9 % of all dermatoses. Role of the bacterial factor in the development of streptococcal pyoderma is obvious. Traditional treatment complex includes antibacterial drugs selected individually, taking into account the antibiotic sensitivity of pathognomonic bacteria, and it is not always effective. Currently implemented immunocorrection methods often do not take into account specific immunological features of the disease, the individual, and the fact that the skin performs the function of not only a mechanical barrier, but it is also an immunocompetent organ. Such an approach makes it necessary to conduct additional studies clarifying the role of factors of innate and adaptive immunity, intercellular mediators and antioxidant defense system, that allow to optimize the treatment of this pathology.

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