scholarly journals Anti-fungal, anti-oxidant, and anti-inflammatory effects of supercritical fluid extracts from Rosa multiflora root

2018 ◽  
Vol 25 (2) ◽  
pp. 263-269
Author(s):  
Young Sim Go ◽  
Sun Eun Choi
Keyword(s):  
Supercritical Fluid ◽  
Rosa Multiflora ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Anti Fungal

scholarly journals Various Phytochemicals Present in Maida Lakdi Litsea glutinosa (Lour) acts in the Management of Waja ul Mafasil (Arthritis) in a Clinical Trials

2021 ◽  
Vol 9 (11) ◽  
pp. 1-8
Author(s):  
Zaibunnisa Begum ◽  
Noor Banu Noorein ◽  
Shenaz Begum Modi
Keyword(s):  
Wound Healing ◽  
Clinical Trials ◽  
Joint Pain ◽  
Classical Text ◽  
Functional Activities ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Traditional Practitioners ◽  
Litsea Glutinosa ◽  
Anti Fungal

Litsea glutinosa (Lour) Maida Lakdi is an evergreen tree belonging to family Lauraceae it is a native to India.1,2,3 Ethinomedically the bark is used by the traditional practitioners as a demulcent, emollient and in the treatment of diarrhea and dysentery. According to ancient Unani classical text books by our ancient scholars which was used for mostly bony diseaseslike Fracture (kasar), Joint pain(Hudaar), gout(Naqras), sciatica(lrqun nasa), anti inflammatory(Muhalil e Auram), spacity of nerves(Tashannunj e Asab), nervine tonic(Muqavi e Asab)etc. and now a days further activities were found by various scientific studies paving a way for multi functional activities like Anti oxidant , analgesic anti inflammatory, anti pyretic, anti microbial, anti bacterial, anti fungal anti helminthic, wound healing, hepatoprotective, nephro protective, anti infertility,anti hyperglycemic and anti hyperlipidemic.

scholarly journals Biological Activities and Phytochemical Constituents of Trailing Daisy Trilobata: A Review

2019 ◽  
Vol 9 (4-s) ◽  
pp. 888-892
Author(s):  
K Sai Prasanna ◽  
G Jyothi Reddy ◽  
M Kiran ◽  
K Thyaga Raju
Keyword(s):  
Skin Diseases ◽  
Biological Activities ◽  
Pharmacological Activities ◽  
Traditional System ◽  
Wedelia Trilobata ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Anti Inflammatory ◽  
Anti Fungal ◽  
Natural Medicines

The traditional system of medicinal plants have been found to possess significant anti-inflammatory, antibacterial, anti-fungal, anti-diabetic, analgesic properties etc. Plant-derived drugs are used to cure mental illness, skin diseases, tuberculosis, diabetes, jaundice, hypertension, and cancer. Wedelia Trilobata belongs to family Asteraceae. Leaf, stem, and flower of Wedelia trilobata show anti-microbial, anti-oxidant and anti-inflammatory activity, analgesic activity. Phytochemical screening of the extract has been reported to show the presence of tannins, cardiac glycosides, flavonoids, terpenoids, phenols, saponins, and coumarins. Wedelia Trilobata is also used in reproductive problems, amenorrhea, chest cold, dry cough, and fever. The present review aims to the study was phytoconstituents, biological and pharmacological activities of Wedelia trilobata. This study suggested a possible use of Wedelia trilobata as a source of natural medicines as an anti-inflammatory, anti-oxidant, anti-microbial, hepatoprotective, antidiabetic agents. Keywords: Wedelia Trilobata, Trialing daisy trilobata, Complaya trilobata(L), Sphagneticola Trilobata, pharmacological review.

scholarly journals An overview on synthesis and reactions of coumarin based compounds

2022 ◽  
Vol 11 (1) ◽  
pp. 29-42 ◽  
Author(s):  
Mahmoud S. Tolba ◽  
Mokhtar A. Abd ul-Malik ◽  
Adel M. Kamal El-Dean ◽  
Ahmed A. Geies ◽  
Shaban M. Radwan ◽  
...  
Keyword(s):  
Oxygen Atom ◽  
Food Additives ◽  
Synthetic Compounds ◽  
Significant Interest ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Anti Fungal ◽  
Anti Hiv ◽  
Natural And Synthetic

Oxygen-containing heterocycles are largely distributed in natural and synthetic compounds. Coumarins are among the most famous heterocycles which possess one oxygen atom in their rings. Coumarins are classified as multifunctional scaffold and are used as anti-oxidant reagents, anti-inflammatory, anti-microbial, anti-fungal, anti-HIV active, analgesic, anti-histaminic, insecticides, dyes, herbicides, sensitizers, perfumes, cosmetics and food additives. Due to their diverse applications in industrial and pharmaceutical fields, many chemists have given significant interest to these compounds. Herein, the review highlights various methods for the synthesis and interactions of coumarin moiety as one of the most efficient categories of heterocycles.

scholarly journals Herbal Formulation for the Treatment of Acne Vulgaris

2019 ◽  
Vol 2 (4) ◽  
Keyword(s):  
Wheat Germ ◽  
Acne Vulgaris ◽  
Hair Follicles ◽  
Wheat Germ Oil ◽  
Skin Cell ◽  
Anti Oxidant ◽  
Inflammatory Skin Disorder ◽  
Anti Inflammatory ◽  
Anti Fungal

The main objective of the present article is to avoid the adverse effect of the existing synthetic acne cream by formulating an herbal acne cream for treatment of acne vulgaris. Acne vulgaris is a long term skin disease that occurs when hair follicles were blocked with dead skin cell and oil from the skin. Acne vulgaris is the most common bacteria causing chronic inflammatory skin disorder. Propioni bacterium and staphylococcus aureus are common pus forming microbes responsible for acne vulgaris. Various herbs used for the treatment of acne vulgaris such as wheat germ oil used as anti-oxidant and it is a great sources of vitamin-e, haldi helps to reduce the inflammation of acne and it act as anti-inflammatory agent, neem helps in clearing acne, scars and pigmentation, raspberry used as anti-oxidant and it is a source of vitamin c, kesar act as anti-inflammatory, anti-fungal and antioxidant. Natural herbal extracts in combination effectively utilized for the treatment of acne. Use of such products far better than the use of synthetic cream for the control of acne. Wheat germ oil which is extracted from kernel of wheat grains, haldi is extracted from rhizome; neem is extracted from leaf, raspberry (seed), kesar extracted from the stigmas of the flower part.

scholarly journals Flavonoids: isolation, characterization, and health benefits

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Abiche Ekalu ◽  
James Dama Habila
Keyword(s):  
Secondary Metabolites ◽  
Health Benefits ◽  
The Body ◽  
Pharmacological Activities ◽  
Potential Health ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Plant Families ◽  
Anti Fungal

Abstract Background The unique and vast pharmacological activities of flavonoids have made them of research interest. This led to the use of various techniques to isolate and characterize them, intending to determine their potential health benefits. Main text The medicinal values of plant-based flavonoids that this literature review tends to summarize the pharmacological activities of these secondary metabolites from 22 selected plant families. The pharmacological shreds of evidence reported in the literature have proven that flavonoids have shown anti-cancer, anti-microbial, anti-oxidant, anti-inflammatory, anti-fungal, anti-ulcer, and anti-edematogenic activities. Out of these, 30% showed to have anti-oxidant activity, key in protecting the body against free radicals. Besides, 18% of the references showed anti-microbial and anti-cancer activities. Further literature reports indicated that flavonoids from these families exhibited anti-inflammatory and anti-edematogenic (9%), anti-viral and anti-ulcer (5%), anti-fungal, anti-nociceptive, and anti-histamine (2%). Conclusion The pharmacological activities of flavonoids from the various sources reviewed in this study show that the secondary metabolites could provide a scaffold for the development of potent anti-cancer drugs in the future.

Pharmacologically potentials of different substituted coumarin derivatives

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Benzene Ring ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Pharmacological Properties ◽  
Coumarin Derivatives ◽  
Wide Range ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Coumarin Compounds

Coumarin and its derivatives are widely spread in nature. Coumarin goes to agroup as benzopyrones, which consists of a benzene ring connected to a pyronemoiety. Coumarins displayed a broad range of pharmacologically useful profile.Coumarins are considered as a promising group of bioactive compounds thatexhibited a wide range of biological activities like anti-microbial, anti-viral,antiparasitic, anti-helmintic, analgesic, anti-inflammatory, anti-diabetic, anticancer,anti-oxidant, anti-proliferative, anti-convulsant, and antihypertensiveactivities etc. The coumarin compounds have immense interest due to theirdiverse pharmacological properties. In particular, these biological activities makecoumarin compounds more attractive and testing as novel therapeuticcompounds.

Effects of Gentiana lutea root on vascular diseases

2020 ◽  
Vol 18 ◽  
Author(s):  
Gordana Joksic ◽  
Djordje Radak ◽  
Emina Sudar-Milovanovic ◽  
Milan Obradovic ◽  
Jelena Radovanovic ◽  
...  
Keyword(s):  
Recent Literature ◽  
Vascular Diseases ◽  
Lipid Lowering ◽  
Primary Data ◽  
Electronic Database ◽  
Active Components ◽  
Gentiana Lutea ◽  
Search Terms ◽  
Anti Oxidant ◽  
Anti Inflammatory

Background: Gentiana lutea (GL), commonly known as yellow gentian, bitter root, and bitterwort, belongs to family Gentianaceae. GL belongs to genus Gentiana, which is a rich natural source of iridoids, secoiridoids, xantones, flavonoids, triterpenoids, and carbohydrates. Medicinal plants from Gentiana species have anti-oxidant, anti-inflammatory, anti-mitogenic, anti-proliferative, and lipid-lowering effects, as well as a cardioprotective, hypotensive, vasodilator and anti-platelet activities. Objective: We reviewed the recent literature related to the effects of Gentiana species, and their active components on vascular diseases. Methods: Data used for this review were obtained by searching the electronic database [PUBMED/MEDLINE 1973 - February 2020]. The primary data search terms of interest were: Gentiana lutea, Gentienacea family, phytochemistry, vascular diseases, treatment of vascular diseases, anti-oxidant, anti-inflammatory, anti-atherogenic. Conclusion: Gentiana species and their constituents affect many different factors related to vascular disease development and progression. Therefore, Gentiana-based therapeutics represent potentially useful drugs for the management of vascular diseases.

Red Grape Polyphenol Oral Administration improves Immune Response in Women Affected by Nickel-Mediated Allergic Contact Dermatitis

2020 ◽  
Vol 20 ◽  
Author(s):  
Thea Magrone ◽  
Emilio Jirillo ◽  
Manrico Magrone ◽  
Matteo Antonio Russo ◽  
Paolo Romita ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Oral Administration ◽  
Allergic Contact Dermatitis ◽  
Laboratory Data ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Red Grape ◽  
Allergic Contact ◽  
Drop Outs

Background: Our previous findings demonstrated that in vitro supplementation of polyphenols, extracted from seeds of red grape (Nero di Troia cultivar), to peripheral lymphomonocytes from patients affected by allergic contact dermatitis (ACD) to nickel (Ni) could reduce release of pro-inflammatory cytokines and nitric oxide (NO), while increasing levels of interleukin (IL)-10, an anti-inflammatory cytokine. Objective: To assess whether an intervention with oral administration of polyphenols leads to a reduction of peripheral biomarkers in ACD patients. Method: At T0, 25 patients affected by ACD to Ni were orally administered with 300 mg polyphenols prodie extracted from seeds of red grape (Nero di Troia cultivar) (NATUR-OX®) for 3 months (T1). Other 25 patients affected by ACD to Ni received placebo only for the same period of time. Serum biomarkers were analyzed at T0 and T1. In both groups seven drop outs were recorded. Result: At T1 in comparison to T0, in treated patients, values of IFN-γ, IL-4, IL-17, PTX3 and NO decreased, while IL-10 levels increased when compared with T0 values. Conversely, in placebo-treated patients no modifications of biomarkers were evaluated at T1. Conclusion: Present laboratory data rely on the anti-oxidant, anti-inflammatory and anti-allergic properties of polyphenols.

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