scholarly journals Non-food crop Rosa canina L leaf and twig extracts as a source of nutrients and bioactive compounds

2020 ◽  
Author(s):  
Małgorzata Kubczak ◽  
Ainur B. Khassenova ◽  
Bartosz Skalski ◽  
Sylwia Michlewska ◽  
Marzena Wielanek ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Conformational Changes ◽  
Antioxidant Properties ◽  
Thiol Group ◽  
Well Being ◽  
Coumaric Acid ◽  
Rosa Canina ◽  
Low Toxicity ◽  
Natural Preservatives

AbstractIt is important to search for new sources of bioactive, natural compounds because customers pay more attention to food quality. Fruits and berries from horticultural plants are known to be good sources of agents beneficial for human well-being and could serve as natural preservatives in the food industry. However, more recent research indicates that other plant organs can also be rich in nutrients. Our study focused on characterizing an unexplored source: leaf and twig extracts from Rosa canina. The chemical composition of these extracts was analyzed and their in vitro activity measured. HPLC analysis of the content of phenolics, vitamins and amino acids revealed that the leaf and twig extracts are rich in bioactive compounds with potent antioxidant properties. The greatest differences between bioactive phenolic compounds in leaf and twig extracts related mainly to p-coumaric acid, myricetin, ellagic acid, cyanidin, procyanidin and quercetin, whereas salicylic acid levels were similar in both types of extract.Interactions with human serum albumin were investigated and some conformational changes in protein structure were observed. Further analysis (lipid peroxidation, protein carbonylation, thiol group oxidation, DPPH inhibition and ROS inhibition) confirmed that both leaf and twig extracts exhibited antioxidant and antiradical scavenging activities. Cytotoxicity and hemotoxicity assays confirmed very low toxicity in the extracts over the range of concentrations tested. Our results indicate that both extracts could serve as non-toxic sources of bioactive compounds with antiradical properties.

scholarly journals Bioactive Compounds and Antiradical Activity of the Rosa canina L. Leaf and Twig Extracts

Agronomy ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1897
Author(s):  
Małgorzata Kubczak ◽  
Ainur B. Khassenova ◽  
Bartosz Skalski ◽  
Sylwia Michlewska ◽  
Marzena Wielanek ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Conformational Changes ◽  
Antioxidant Properties ◽  
Thiol Group ◽  
Well Being ◽  
Coumaric Acid ◽  
Rosa Canina ◽  
Low Toxicity ◽  
Natural Preservatives

It is important to search for new sources of bioactive, natural compounds, because customers are paying more attention to food quality. Fruits and berries from horticultural plants are known to be good sources of agents beneficial for human well-being and could serve as natural preservatives in the food industry. However, more recent research indicates that other plant organs can also be rich in nutrients. Our study focused on characterizing an unexplored source, namely leaf and twig extracts from Rosa canina. The chemical composition of these extracts was analyzed and their in vitro activity measured. HPLC analysis of the content of phenolics, vitamins and amino acids revealed that the leaf and twig extracts were found to be rich in bioactive compounds with potent antioxidant properties. The greatest differences between bioactive phenolic compounds in leaf and twig extracts related mainly to p-coumaric acid, myricetin, ellagic acid, cyanidin, procyanidin and quercetin, whereas salicylic acid levels were similar in both types of extract. Interactions with human serum albumin were investigated, and some conformational changes in protein structure were observed. Further analysis (lipid peroxidation, protein carbonylation, thiol group oxidation, DPPH inhibition and ROS inhibition) confirmed that both leaf and twig extracts exhibited antioxidant and antiradical scavenging activities. Cytotoxicity and hemotoxicity assays confirmed very low toxicity of the extracts towards human cells over the range of concentrations tested. Our results indicate that both extracts could serve as non-toxic sources of bioactive compounds with antiradical properties.

scholarly journals In Vitro Gastrointestinal Digestion Impact on the Bioaccessibility and Antioxidant Capacity of Bioactive Compounds from Tomato Flours Obtained after Conventional and Ohmic Heating Extraction

Foods ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 554
Author(s):  
Marta C. Coelho ◽  
Tânia B. Ribeiro ◽  
Carla Oliveira ◽  
Patricia Batista ◽  
Pedro Castro ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Phenolic Compounds ◽  
Antioxidant Capacity ◽  
Bioactive Compounds ◽  
Solid Fraction ◽  
Ohmic Heating ◽  
Coumaric Acid ◽  
Insoluble Dietary Fiber ◽  
The Impact

In times of pandemic and when sustainability is in vogue, the use of byproducts, such as fiber-rich tomato byproducts, can be an asset. There are still no studies on the impact of extraction methodologies and the gastrointestinal tract action on bioactive properties. Thus, this study used a solid fraction obtained after the conventional method (SFCONV) and a solid fraction after the ohmic method (SFOH) to analyze the effect of the gastrointestinal tract on bioactive compounds (BC) and bioactivities. Results showed that the SFOH presents higher total fiber than SFCONV samples, 62.47 ± 1.24–59.06 ± 0.67 g/100 g DW, respectively. Both flours present high amounts of resistant protein, representing between 11 and 16% of insoluble dietary fiber. Furthermore, concerning the total and bound phenolic compounds, the related antioxidant activity measured by 2,2′-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) radical cation decolorization assay presented significantly higher values for SFCONV than SFOH samples (p < 0.05). The main phenolic compounds identified in the two flours were gallic acid, rutin, and p-coumaric acid, and carotenoids were lycopene, phytofluene, and lutein, all known as health promoters. Despite the higher initial values of SFCONV polyphenols and carotenoids, these BCs’ OH flours were more bioaccessible and presented more antioxidant capacity than SFCONV flours, throughout the simulated gastrointestinal tract. These results confirm the potential of ohmic heating to modify the bioaccessibility of tomato BC, enhancing their concentrations and improving their antioxidant capacity.

scholarly journals Black goji berry (Lycium ruthenicum) tea has higher phytochemical contents and in vitro antioxidant properties than red goji berry (Lycium barbarum) tea

2020 ◽  
Vol 4 (4) ◽  
pp. 193-201
Author(s):  
Bei Liu ◽  
Qingqing Xu ◽  
Yujing Sun
Keyword(s):  
Antioxidant Capacity ◽  
Bioactive Compounds ◽  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Antioxidant Property ◽  
Lycium Barbarum ◽  
Antioxidant Power ◽  
Goji Berry ◽  
Good Habit

Abstract Goji berry tea, a traditional herbal tea, is the main ate mode of goji berry in Asia, yet few studies in comparison with red goji berry tea and black goji berry tea are carried out. This study investigated the effects of water temperature and soak time on the colour, phytochemicals, and the antioxidant capacity [2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl radical (DPPH), and the ferric-reducing antioxidant power (FRAP)] of two goji berry tea. A comparison of the bioactive compounds and antioxidant activities between black and red goji berry tea was conducted. Results showed that both red and black goji berry tea were rich in phytochemicals, giving high antioxidant ability. The levels of bioactive compounds and the antioxidant activity of the two goji berry tea increased as the increases in soak temperature and time. Black goji berry tea had higher phytochemicals and antioxidant property than those of red goji berry tea. Infused at 100° water for the same time, the levels of total polysaccharides (150 mg/100 ml), total polyphenols (238 mg/ml), and antioxidant capacity (550 μmol/100 ml) of black goji berry tea were 3.5, 2, and 5 times higher, respectively, in comparison with red goji berry tea. The results of this study demonstrate that hot drink of goji berry in China is a good habit and black goji berry tea may be a better choice.

scholarly journals In vitro and in vivo antioxidant properties of bioactive compounds from green propolis obtained by ultrasound-assisted extraction

2019 ◽  
Vol 4 ◽  
pp. 100054 ◽  
Author(s):  
Renata Iara Cavalaro ◽  
Richtier Gonçalves da Cruz ◽  
Sebastien Dupont ◽  
Juliana Maria Leite Nóbrega de Moura Bell ◽  
Thais Maria Ferreira de Souza Vieira
Keyword(s):  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Ultrasound Assisted Extraction ◽  
Assisted Extraction ◽  
Ultrasound Assisted

scholarly journals Ultrasound processing to enhance drying of cashew apple bagasse puree: Influence on antioxidant properties and in vitro bioaccessibility of bioactive compounds

2016 ◽  
Vol 31 ◽  
pp. 237-249 ◽  
Author(s):  
Thatyane Vidal Fonteles ◽  
Ana Karoline Ferreira Leite ◽  
Ana Raquel Araújo Silva ◽  
Alessandra Pinheiro Góes Carneiro ◽  
Emilio de Castro Miguel ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Cashew Apple Bagasse ◽  
Cashew Apple ◽  
In Vitro Bioaccessibility

scholarly journals Valorization of Natural Antioxidants for Nutritional and Health Applications

2021 ◽  
Author(s):  
Pedro Ferreira-Santos ◽  
Zlatina Genisheva ◽  
Claudia Botelho ◽  
Cristina Rocha ◽  
José António Teixeira
Keyword(s):  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Chemical Properties ◽  
Health Benefit ◽  
Natural Antioxidants ◽  
Extraction Process ◽  
Extraction Methods ◽  
In Vivo Studies

The significant increase in the world population age, 47 years in 1950 to 73 years in 2020, resulted in an increase in aging related diseases as well as in degenerative diseases. In consequence, researchers have been focusing in the development of new therapies, with a particular emphasis on the use of compounds with antioxidant properties, namely phytochemicals, such as polyphenols and carotenoids. Several in vitro and in vivo studies have demonstrated the phytochemicals antioxidant capacity. Their use is broad, as they can be part of food supplements, medicine and cosmetics. The health benefit of antioxidant phytochemicals is an indisputable question. Phytochemical properties are highly influenced by the natural matrix as well as by extraction process, which have a key role. There are several extraction methods that can be applied depending on the chemical properties of the bioactive compounds. There is a wide range of solvents with different polarities, which allows a selective extraction of the desired target family of compounds. Greener technologies have the advantage to reduce extraction time and solvent quantity in comparison to the most traditional methods. This chapter will focus on the different green extraction strategies related to the recovery of antioxidant bioactive compounds from natural sources, their nutritional and health potential.

scholarly journals Evaluation Of In Vitro Antioxidant, Phytochemical and Gc-Ms Analysis of Aqueous Extract of Solanum Dasyphyllum Fruits

2021 ◽  
Vol 7 (4) ◽  
pp. 19-25
Author(s):  
Otor Matthew ◽  
◽  
Tosin Fabunmi ◽  
Ofikwu Idoko ◽  
Bakare Ebun ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Aqueous Extract ◽  
Cardiac Glycosides ◽  
Antioxidant Properties ◽  
Antioxidant Property ◽  
Scavenging Activity ◽  
Fruit Extract ◽  
Ms Analysis

Phytochemicals, antioxidant and the bioactive compounds present in the fruits of Solanum dasyphullum was investigated. Several phytochemicals such as saponins, tannins, alkaloids, flavonoids, steroids and cardiac glycosides were detected. A total of 172 compounds were identified by GC-MS. Phenols, spermine, 2, 5- dimethylfuran and 2-methyl-1-hexadecanol were all identified. These compounds are known to have antioxidant property which may be responsible for the antioxidant property of the fruit extract. It was observed that the fruits extract exhibit antioxidant properties. The scavenging activity increases with the concentration of the extract with the following percentage scavenging activity; 200µg(90%),133µg (78%), 100 µg(69%), 67 µg(48), 33 µg(26.7%), 20 µg(18), 7 µg(7%). Compounds identified in the fruits of Solanum dasyphylum can be isolated and used as an antioxidant. Keywords: Solanum dasyphylum, oxidation, antioxidant and extracts.

scholarly journals The Effect of an Edible Coating with Tomato Oily Extract on the Physicochemical and Antioxidant Properties of Garambullo (Myrtillocactus geometrizans) Fruits

Agronomy ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 248 ◽  
Author(s):  
César López-Palestina ◽  
César Aguirre-Mancilla ◽  
Juan Raya-Pérez ◽  
Juan Ramírez-Pimentel ◽  
Jorge Gutiérrez-Tlahque ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Titratable Acidity ◽  
Trolox Equivalent Antioxidant Capacity ◽  
Trolox Equivalent ◽  
Gelatin Coating ◽  
Reduced Water ◽  
Capacity Method

The Myrtillocactus geometrizans (Mart. ex. Pfeiff.) fruit, locally called garambullo, is an important source of bioactive compounds, mainly betalains, polyphenols, and ascorbic acid. However, information on the application of post-harvest technologies that prolong the shelf life of the fruits is still insufficient. The objective of the present research was to evaluate the effect of a gelatin coating incorporating 0%, 1%, or 3% tomato oily extract (TOE), compared to a control (without coating), on the physicochemical and antioxidant properties of garambullo fruits stored for 15 days at 5 °C. The gelatin coatings with TOE significantly (p ≤ 0.05) delayed changes in weight loss, brix degrees, titratable acidity and pH, compared to the control during storage. Fruits coated with TOE-gelatin had a higher content of betalains, ascorbic acid, total phenols, and flavonoids. The results showed that a higher concentration of phytochemicals increased antioxidant activity in vitro; the maximum values found for Trolox equivalents per kg of fresh weight were 10.46 and 17.65 mM for the 2,2′-diphenyl-1-picrylhydrazyl (DPPH) and Trolox Equivalent Antioxidant Capacity Method (TEAC) tests, respectively. The gelatin coating with TOE-3% (COTE-3%) reduced water loss by 1.66 times, compared to the control. In addition, the fruits covered with COTE-3% showed the highest concentration of bioactive compounds during storage.

scholarly journals Oxidative Stress Modulation and ROS-Mediated Toxicity in Cancer: A Review on In Vitro Models for Plant-Derived Compounds

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
María José Vallejo ◽  
Lizeth Salazar ◽  
Marcelo Grijalva
Keyword(s):  
Oxidative Stress ◽  
Cancer Cells ◽  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Cancer Cell Line ◽  
Cancer Therapeutics ◽  
Antioxidant Defenses ◽  
Medicinal And Aromatic Plants

Medicinal and aromatic plants (MAPs) are known and have been long in use for a variety of health and cosmetics applications. Potential pharmacological usages that take advantage of bioactive plant-derived compounds’ antimicrobial, antifungal, anti-inflammatory, and antioxidant properties are being developed and many new ones explored. Some phytochemicals could trigger ROS-mediated cytotoxicity and apoptosis in cancer cells. A lot of effort has been put into investigating novel active constituents for cancer therapeutics. While other plant-derived compounds might enhance antioxidant defenses by either radical scavenging or stimulation of intracellular antioxidant enzymes, the generation of reactive oxygen species (ROS) leading to oxidative stress is one of the strategies that may show effective in damaging cancer cells. The biochemical pathways involved in plant-derived bioactive compounds’ properties are complex, and in vitro platforms have been useful for a comprehensive understanding of the mechanism of action of these potential anticancer drugs. The present review aims at compiling the findings of particularly interesting studies that use cancer cell line models for assessment of antioxidant and oxidative stress modulation properties of plant-derived bioactive compounds.

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