scholarly journals Continuously Active Antimicrobial Coating Remains Effective After Multiple Contamination Events

2020 ◽  
Author(s):  
Luisa A. Ikner ◽  
Valerie Beck ◽  
Patrica M. Gundy ◽  
Charles P Gerba
Keyword(s):  
Surface Coating ◽  
Pathogenic Bacteria ◽  
Surface Coatings ◽  
Antimicrobial Coating ◽  
Source Of Infection ◽  
Potential Source ◽  
Environmental Surfaces ◽  
Pathogen Burden ◽  
Contamination Events ◽  
Routine Cleaning

Liquid-based disinfection of environmental surfaces is a momentary intervention while the recontamination of these surfaces is continuous. In between disinfection cycles, contaminated surfaces remain a potential source of infection. The use of continuously active antimicrobial surface coatings would reduce the risk of transmission between routine cleaning and liquid disinfection events by serving as an always-on approach to reduce pathogen burden. We have recently reported on a surface coating having antiviral properties. Here, the spectrum of activity was broadened assessment efficacy of the coating to withstand multiple contamination events against viruses and pathogenic bacteria.

scholarly journals Novel Antimicrobial Surfaces to Defeat COVID-19 Transmission

MRS Advances ◽  
2020 ◽  
Vol 5 (56) ◽  
pp. 2839-2851
Author(s):  
Rodica Cristescu ◽  
Roger J. Narayan ◽  
Douglas B. Chrisey
Keyword(s):  
Surface Coating ◽  
Laser Processing ◽  
Surface Contamination ◽  
Surface Coatings ◽  
Microbial Colonization ◽  
Antimicrobial Surfaces ◽  
Environmental Surfaces ◽  
Contact Transmission

AbstractAntimicrobial surface coatings function as a contact biocide and are extensively used to prevent the growth and transmission of pathogens on environmental surfaces. Currently, scientists and researchers are intensively working to develop antimicrobial, antiviral coating solutions that would efficiently impede/stop the contagion of COVID-19 via surface contamination. Herein we present a flavonoid-based antimicrobial surface coating fabricated by laser processing that has the potential to eradicate COVID-19 contact transmission. Quercetin-containing coatings showed better resistance to microbial colonization than antibiotic–containing ones.

scholarly journals Bodipy-Loaded Micelles Based on Polylactide as Surface Coating for Photodynamic Control of Staphylococcus aureus

Coatings ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 223
Author(s):  
Enrico Caruso ◽  
Viviana Teresa Orlandi ◽  
Miryam Chiara Malacarne ◽  
Eleonora Martegani ◽  
Chiara Scanferla ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pathogenic Bacteria ◽  
Surface Coatings ◽  
Supramolecular System ◽  
Amphiphilic Copolymers ◽  
Oxygen Penetration ◽  
Short Period ◽  
Excellent Activity ◽  
Coating Matrix ◽  
Photodynamic Control

Decontaminating coating systems (DCSs) represent a challenge against pathogenic bacteria that may colonize hospital surfaces, causing several important infections. In this respect, surface coatings comprising photosensitizers (PSs) are promising but still controversial for several limitations. PSs act through a mechanism of antimicrobial photodynamic inactivation (aPDI) due to formation of reactive oxygen species (ROS) after light irradiation. However, ROS are partially deactivated during their diffusion through a coating matrix; moreover, coatings should allow oxygen penetration that in contact with the activated PS would generate 1O2, an active specie against bacteria. In the attempt to circumvent such constraints, we report a spray DCS made of micelles loaded with a PS belonging to the BODIPY family (2,6-diiodo-1,3,5,7-tetramethyl-8-(2,6-dichlorophenyl)-4,4′-difluoroboradiazaindacene) that is released in a controlled manner and then activated outside the coating. For this aim, we synthesized several amphiphilic copolymers (mPEG–(PLA)n), which form micelles, and established the most stable supramolecular system in terms of critical micelle concentration (CMC) and ∆Gf values. We found that micelles obtained from mPEG–(PLLA)2 were the most thermodynamically stable and able to release BODIPY in a relatively short period of time (about 80% in 6 h). Interestingly, the BODIPY released showed excellent activity against Staphylococcus aureus even at micromolar concentrations.

scholarly journals Impact of anti-biofouling surface coatings on the properties of nanomaterials and their biomedical applications

2018 ◽  
Vol 6 (1) ◽  
pp. 9-24 ◽  
Author(s):  
Yuancheng Li ◽  
Yaolin Xu ◽  
Candace C. Fleischer ◽  
Jing Huang ◽  
Run Lin ◽  
...  
Keyword(s):  
Surface Coating ◽  
Biomedical Applications ◽  
Biological Systems ◽  
Surface Coatings ◽  
Specific Interactions ◽  
Coating Materials

Various anti-biofouling surface coating materials for nanoparticles have been reviewed for the reduction of their non-specific interactions with biological systems.

IMPORTANCE OF TOOTH-BRUSH DISINFECTION IN SARS Cov-2.

2021 ◽  
pp. 1-1
Author(s):  
Akash Bhatt ◽  
Neel Gupta ◽  
Lavisha Garg
Keyword(s):  
Viral Load ◽  
Severe Acute Respiratory Syndrome ◽  
Family Members ◽  
Cross Infection ◽  
Viable Option ◽  
Source Of Infection ◽  
Potential Source

As public distribution of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is underway, prevention of coronavirus disease 2019 (COVID-19) relies on minimizing spread. Toothbrushes are a potent source of infection as it harbours the microorganisms and increases the viral load as well. It also increases the chances of cross infection among family members. Therefore disinfecting toothbrushes after every use may be a viable option to decrease the total viral load as well as to limit the chances of cross - infection. This communication aims to focus on the fact that toothbrushes may be another potential source of infection in this pandemic, thereby this needs to be disinfected after every use and once person is recovered, it should be replaced with a new one.

scholarly journals Ultrasound scan as a potential source of nosocomial and cross-infection: a literature review

2015 ◽  
Vol 48 (5) ◽  
pp. 319-323 ◽  
Author(s):  
André Hadyme Miyague ◽  
Fernando Marum Mauad ◽  
Wellington de Paula Martins ◽  
Augusto César Garcia Benedetti ◽  
Ana Elizabeth Gomes de Melo Tavares Ferreira ◽  
...  
Keyword(s):  
Literature Review ◽  
Cost Benefit ◽  
Cross Infection ◽  
Ultrasound Scan ◽  
Benefit Ratio ◽  
Source Of Infection ◽  
Potential Source ◽  
Cost Benefit Ratio ◽  
The Cost

AbstractThe authors review the main concepts regarding the importance of cleaning/disinfection of ultrasonography probes, aiming a better comprehension by practitioners and thus enabling strategies to establish a safe practice without compromising the quality of the examination and the operator productivity. In the context of biosafety, it is imperative to assume that contact with blood or body fluids represents a potential source of infection. Thus, in order to implement cleaning/disinfection practice, it is necessary to understand the principles of infection control, to consider the cost/benefit ratio of the measures to be implemented, and most importantly, to comprehend that such measures will not only benefit the health professional and the patient, but the society as a whole.

scholarly journals Nano Silver Coated Surgical Apparels and Phaco Needles for Safety of Ophthalmic Surgeons in View of COVID-19 Pandemic

2021 ◽  
Vol 15 (1) ◽  
pp. 9-12
Author(s):  
Santosh Dnyanmote ◽  
Jorge Alio ◽  
Anuradha Dnyanmote
Keyword(s):  
Healthcare System ◽  
Healthcare Workers ◽  
Respiratory Virus ◽  
Hospital Staff ◽  
Infected Person ◽  
Source Of Infection ◽  
Potential Source ◽  
Corona Virus ◽  
Co Morbidity ◽  
Recent Outbreak

Background: In view of the recent outbreak of the pandemic caused by novel corona virus 19 (n-covid) which has thrown the overall healthcare system that has created fear, apprehension and anxiety amongst all surgeons. Ophthalmic surgeons are no exceptions. The new corona virus is a respiratory virus of the Coronoviridae family containing a single strand of RNA which spreads primarily through droplets generated when an infected person coughs or sneezes or through droplets of saliva or discharge from the nose. A person can get infected by the virus if the person is within 1 meter of a person with COVID 19 or by touching contaminated surface and then touching eyes, nose or mouth. Methods: Standard recommendations to prevent the spread of COVID-19 include frequent cleaning of hands using alcohol based hand rubs or soap and water. Covering the nose and mouth with a proper mask, covering skin, eyes, hair, hands and legs with proper apparel is important. Just like elderly members of the society, the healthcare workers who have some co-morbidity are susceptible to COVID-19 invasion. Asymptomatic carriers who may present with senile or pre-senile cataract can be a potential source of infection to other patients, hospital staff, surgeons and others. Conclusion: It is important that all the microsurgical instruments which will be used for phacoemulsification be properly sterilized. The surfaces of these instruments should remain free of contaminants as these instruments will be used multiple times in other patients as well.

scholarly journals Detection of pathogenic bacteria associated with earphones used by students of Stamford University Bangladesh

2020 ◽  
Vol 10 (1) ◽  
pp. 1-4
Author(s):  
Omor Ahmed Chowdhury ◽  
Md Raihan Ahmed ◽  
Md Raihan Dipu ◽  
Md Aftab Uddin
Keyword(s):  
Pathogenic Bacteria ◽  
Diffusion Method ◽  
Resistant Bacteria ◽  
Bacterial Isolates ◽  
Biochemical Tests ◽  
Disk Diffusion Method ◽  
Antibiotic Resistant ◽  
Potential Source ◽  
Different Types ◽  
Staphylococcus Spp

The use of earphones has increased in recent times throughout the world especially among the different level of students such as school, college or university who have a higher tendency of sharing these among them. Unlike airline headsets, headphones and stethoscope ear-pieces, ear phones are often shared by multiple users and can be a potential medium for transmission of pathogens, which can give rise to various ear related infections. The objective of this study was to detect the pathogenic bacteria from the ear-phones used by the students of Stamford University Bangladesh. A total of 16 ear-phone swabs were collected by sterile cotton swabs. The swabs were inoculated onto blood agar and incubated aerobically overnight at 37oC. Microscopic observation and standard biochemical tests were performed to confirm the identification of all the bacterial isolates. Six presumptively identified Staphylococcus spp. (38%) were tested against six different types of antibiotics following Kirby-Bauer disk diffusion method. Isolates were found to be 84% resistant against Cotrimoxazole and demonstrated 100% sensitivity to Vancomycin and Ciprorofloxacin. The findings of this study suggest the users to disinfect their respective ear phones and not to exchange them as they may act as a potential source to transfer pathogenic and antibiotic resistant bacteria among the ear phone users. Stamford Journal of Microbiology, Vol.10 (1) 2020: 1-4

scholarly journals Effectiveness of an Antimicrobial Polymer to Decrease Contamination of Environmental Surfaces in the Clinical Setting

2014 ◽  
Vol 35 (8) ◽  
pp. 1060-1062 ◽  
Author(s):  
Kerri A. Thom ◽  
Harold C. Standiford ◽  
J. Kristie Johnson ◽  
Nader Hanna ◽  
Jon P. Furuno
Keyword(s):  
Real World ◽  
Environmental Contamination ◽  
Clinical Setting ◽  
Pathogenic Bacteria ◽  
Infect Control Hosp ◽  
Environmental Surfaces

We performed a real-world, controlled intervention to investigate use of an antimicrobial surface polymer, MSDS Poly, on environmental contamination. Pathogenic bacteria were identified in 18 (90%) of 20 observations in treated rooms and 19 (83%) of 23 observations in untreated rooms (P = .67). MSDS Poly had no significant effect on environmental contamination.Infect Control Hosp Epidemiol 2014;35(8):1060–1062

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