scholarly journals Quality of life and depressive symptoms among Peruvian university students during the COVID-19 pandemic

2020 ◽  
Author(s):  
Joel Figueroa-Quiñones ◽  
Miguel Ipanaqué-Zapata ◽  
Daniel Machay-Pak ◽  
Juan Rodríguez-Ruiz

AbstractObjectivesCharacterize the quality of life and depressive symptoms of university students in Peru during the COVID-19 pandemic and to determine the associated factors.MethodsMulti-centre study in 1634 university students recruited by convenience sampling. Quality of life (QoL) was assessed with the European Quality of Life-5 Dimensions at three levels (EQ-5D-3L) and depressive symptoms with the Patient Health Questionarie-9 (PHQ-9). To evaluate factors associated with QoL and depressive symptoms, linear and adjusted regressions were used, with robust variance reporting coefficients (β).ResultsThe percentage of participants most affected by QoL dimension was: anxiety/depression (47.2%) and pain/discomfort (35.6%). Regarding the Visual Analog Scale (EQ-VAS) of QoL, the score was 76.0 + 25.6. Those who had family economic decline during quarantine (β=-3.4, IC95%=-6.5 to −0.3) or family with chronic diseases (β=-3.7, IC95%=-6.1 to −1.4) presented significantly lower scores in their QoL. Regarding depressive symptomatology, the university students reported a moderate to severe level (28.9%). A higher risk of depressive symptoms was found in residents of Ayacucho (β=0.8, IC95%=0.1 to 1.5), those who were released from quarantine (β=0.7, IC95%=0.2 to 1.2) and those who had a family member with chronic disease (β=1.5, IC95%=1.0 to 2.1).ConclusionsAlmost half and one third of participants reported anxiety/depression, and pain/discomfort in their QoL respectively. Nearly a third presented moderate and severe depressive symptoms. The deterioration of QoL was worse in those who had a decrease in income and a family member with chronic illness. The presence of depressive symptoms was found in students in Ayacucho, those who left home during quarantine and those who had a family member with chronic diseases.

Author(s):  
Jorge Osma ◽  
Víctor Martínez-Loredo ◽  
Amanda Díaz-García ◽  
Alba Quilez-Orden ◽  
Óscar Peris-Baquero

The lifetime prevalence of emotional disorders in Spain is 4.1% for anxiety and 5.2% for depression, increasing among university students. Considering the scarcity of screenings with adequate psychometric properties, this study aims to explore the validity evidence of the Overall Anxiety/Depression Severity and Impairment Scales (OASIS and ODSIS). A total of 382 university students from the general population were assessed on anxiety and depressive symptoms, as well as quality of life. The one-dimensional structure of both the OASIS and ODSIS explained 87.53% and 90.60% of variance, with excellent internal consistency (α = 0.94 and 0.95, respectively) and optimal cut-offs of 4 and 5, respectively. Both scales show a significant moderate association with other measures of anxiety, depression and quality of life. The OASIS and ODSIS have shown good reliability and sound validity evidence that recommend their use for the assessment and early detection of anxiety and depressive symptoms, and associated quality of life impairment in Spanish youth.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S160-S160
Author(s):  
Weiwen Ng ◽  
Yinfei Duan ◽  
Tetyana P Shippee

Abstract The Patient Health Questionnaire-9 (PHQ-9) is a depressive symptom questionnaire administered to nursing facility (NF) residents in the Minimum Data Set (MDS). Does the PHQ-9 measure mood-related aspects of quality of life (QoL)? We assessed the PHQ-9’s convergent validity with negative and positive mood items from Minnesota’s QoL survey, which is administered annually to a random sample of residents. We also examined if scores on both instruments were associated with various psychiatric diagnoses on the MDS. Using item response theory (IRT) models, we estimated that depressive symptoms (PHQ-9) had a correlation of 0.546 with negative mood and -0.425 with positive mood. With explanatory IRT modeling, we estimated that diagnoses of anxiety, depression, and bipolar disorder were respectively associated with 0.261, 0.339, and 0.301 (all p < 0.001) standard deviation increases in (SD) depressive symptoms, and with 0.235, 0.261, and 0.306 SD increases in negative mood (all p < 0.001), thus indicating convergent validity. For positive mood, depression and bipolar disorder had associations of similar magnitude as the other two constructs. However, anxiety disorders were not associated with lower positive mood (-0.014 SD, p = 0.636). Thus, the PHQ-9 can measure mood-related aspects of QoL. However, the PHQ-9 appears to be sensitive to relatively serious depression, whereas the Minnesota items are more sensitive to lower levels of negative mood. Also, the PHQ-9 does not measure positive mood directly. Thus, the PHQ-9 is a more limited measure of mood-related QoL than the Minnesota items.


Kidney360 ◽  
2020 ◽  
Vol 1 (6) ◽  
pp. 436-446 ◽  
Author(s):  
L. Parker Gregg ◽  
Thomas Carmody ◽  
Dustin Le ◽  
Nina Bharadwaj ◽  
Madhukar H. Trivedi ◽  
...  

BackgroundInflammatory biomarkers are elevated in patients with CKD and associated with poor outcomes. Major depressive disorder (MDD) is prevalent in CKD and associated with inflammation. No studies investigated the effect of MDD treatment on plasma inflammatory biomarkers in patients with nondialysis CKD.MethodsIn a prespecified analysis of the randomized, double-blind CKD Antidepressant Sertraline Trial, we investigated whether treatment with sertraline versus placebo or response to treatment would affect plasma levels of albumin, prealbumin, IL-6, and high-sensitivity C-reactive protein (hsCRP), measured at baseline and after 12 weeks of treatment. We also explored whether somatic versus nonsomatic depressive symptoms, measured using the Quick Inventory of Depressive Symptomatology, and quality-of-life subscales, measured using the Kidney Disease Quality of Life Short Form, were associated with baseline levels of these inflammatory biomarkers.ResultsOf the 193 participants, mean age was 58.4 (SD 13) years and 58% were black, 42% were white, and 18% were Hispanic. Higher baseline hsCRP correlated with somatic depressive symptoms (r=0.21; P=0.01), fatigue (r=0.22; P=0.005), and poorer physical functioning (r=−0.26; P=0.001). There was no change in hsCRP in the sertraline group. hsCRP increased in placebo nonresponders from baseline (median, 3.7 mg/L; interquartile range [IQR], 1.7–10.0 mg/L) to exit (median, 4.9 mg/L; IQR, 1.8–8.8 mg/L; P=0.01). The change from baseline to exit differed between placebo responders (median, −0.4 mg/L; IQR, −9.3 to 0.2 mg/L) and nonresponders (median, 0.8 mg/L; IQR, −0.1 to 3.9 mg/L; P=0.008). There were no differences in changes in albumin, prealbumin, or IL-6 from baseline in any group.ConclusionsAmong patients with CKD and MDD, hsCRP correlated with somatic symptoms of depression and fatigue, but not with nonsomatic symptoms. Sertraline treatment was not associated with a longitudinal change in hsCRP from baseline regardless of treatment effect on depressive symptoms, but those who failed to respond to placebo had an increase in hsCRP over time. This area deserves further investigation.Clinical Trial registry name and registration number:CKD Antidepressant Sertraline Trial (CAST), NCT00946998.


2020 ◽  
Vol 9 (10) ◽  
pp. 3110
Author(s):  
Julia E. Marquez-Arrico ◽  
José Francisco Navarro ◽  
Ana Adan

Health-related quality of life (HRQoL) assessment has interest as an indicator of degree of affectation and prognosis in mental disorders. HRQoL is impaired in both Substance Use Disorder (SUD) and Major Depressive Disorder (MDD), two conditions highly prevalent, although less studied when both are coexisting (SUD + MDD). Hence, we decided to explore HRQoL with the SF-36 survey in a sample of 123 SUD and 114 SUD + MDD patients (51 symptomatic and 63 asymptomatic of depressive symptoms) under treatment. We performed analyses to examine HRQoL among groups, and its predictive value at 3-, 6- and 12-month follow-ups through regression models. Patients with SUD + MDD had worse HRQoL than SUD patients and population norms. For Mental Health, Vitality, and General Health dimensions, lower scores were observed for SUD + MDD regardless the presence/absence of depressive symptoms. For Physical Functioning and Health Change, depressive symptomatology and not the comorbidity of SUD + MDD diagnoses explained HRQoL limitations. At 3-, 6- and 12-month follow-ups we observed two predictors of relapses, General Health for asymptomatic SUD + MDD, and Physical Functioning for SUD. Improving HRQoL in SUD + MDD may be targeted during patient’s treatment; future studies should explore the influence of HRQoL on patient’s prognosis taking into account the presence/absence of depressive symptomatology.


Author(s):  
Isabel Gil ◽  
Paulo Costa ◽  
Vítor Parola ◽  
Daniela Cardoso ◽  
Maria Almeida ◽  
...  

ABSTRACT Objective: To identify the best available evidence on the efficacy of Reminiscence Therapy in cognition, depressive symptoms and quality of life in elderly individuals with cognitive impairment. Method: The methodology proposed by the Joanna Briggs Institute was used. Studies focused on group Reminiscence Therapy aimed at institutionalized elderly people with cognitive impairment aged 65 or over were considered. The critical analysis, extraction and synthesis of results was performed by two independent researchers. Results: Four randomized clinical trials and two quasi-experimental studies (n=296) were included. Given the heterogeneous characteristics of studies found, it was impossible to perform a meta-analysis. Of the six studies included, two presented statistically significant results for efficacy in cognition, and three for efficacy in reducing depressive symptoms. In none of the studies was evaluated the elderly’s quality of life. Conclusion: Reminiscence Therapy has potential efficacy for maintaining cognition and decrease of depressive symptomatology in the target population.


Circulation ◽  
2021 ◽  
Vol 144 (Suppl_2) ◽  
Author(s):  
Katharyn L Flickinger ◽  
Melissa Repine ◽  
Kara Deliman ◽  
Elizabeth R Skidmore ◽  
Jon Rittenberger ◽  
...  

Introduction: Over 70,000 Americans are discharged from the hospital after surviving cardiac arrest (CA) each year. CA survivors experience depressive symptoms that adversely affect quality of life. Exercise, facilitated through cardiac rehabilitation (CR), improves mood after traumatic brain injury. CR is inconsistently offered to CA survivors but may improve recovery. Aims: Determine if: 1) CA survivors receiving CR have less severe depressive symptoms than CA survivors who do not receive CR, and 2) CA survivors receiving CR have less severe depressive symptoms after CR than before. Methods: Chart review including CA survivors between 2016-2019 who received CR or were enrolled in the control arm of a randomized trial in which depression was assessed prospectively. Demographic and cardiac arrest characteristics were recorded for all patients. The Patient Health Questionnaire (PHQ-9) used to quantify depressive symptoms in CR participants at the beginning and end of 12-36 sessions of CR. PHQ-9 was also assessed 6 months after hospital discharge in control subjects. We compared PHQ-9 within and between groups using t-tests. Results: We included 25 patients (15 male), with mean age 54 (SD 17) years, 16 of whom CR and 9 of whom were enrolled in the trial’s control arm. In patients who received CR, PHQ-9 score decreased from a mean of 5 (SD 5) before CR to mean of 1 (SD 1) after CR [difference -4 (95% CI -4 to -1; p=0.01)]. Among patients who received CR, mean PHQ-9 after CR was lower than that of controls 6 months after discharge [control group mean 6 (SD 5); difference -5 (95% CI -9 to -2; p=0.001)]. Conclusions: CR may improve depressive symptoms in CA survivors. Future studies should investigate other benefits, dose-response and optimal timing of CR.


2017 ◽  
Vol 36 (4) ◽  
pp. 332-340 ◽  
Author(s):  
Luciano Magalhães Vitorino ◽  
Renata de Castro e Santos Soares ◽  
Ana Eliza Oliveira Santos ◽  
Alessandra Lamas Granero Lucchetti ◽  
Jonas Preposi Cruz ◽  
...  

Background: Studies have shown that spiritual/religious beliefs are associated with mental health and health-related quality of life (HRQoL). However, few studies evaluated how spiritual/religious coping (SRC) could affect hemodialysis patients. Objectives: The present study investigated the role of SRC behaviors on HRQoL and depressive symptoms in hemodialysis patients. Design and Participants: This was cross-sectional study with 184 patients. Patients completed the Beck Depression Inventory, Brief SRC Scale, Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36), and a Sociodemographic and Health Characterization Questionnaire. Results: From 218 patients, 184 (84.4%) were included (53.8% male with a median age of 55.9 years). Negative SRC, but not positive SRC, was associated with depressive symptoms. Positive SRC presented significant effects in SF-36 pain and physical and social functioning. On the other hand, negative SRC exhibited significant effects in SF-36 role emotional, energy/fatigue, pain, and physical functioning. Conclusion: SRC influences the mental health and HRQoL in Brazilian hemodialysis patients in two distinct ways. If used positively, it may have positive outcomes. However, if used negatively, it may lead to dysfunctional consequences such as greater depressive symptomatology and affect HRQoL. Health professionals must be aware of these “two sides of the same coin.”


2015 ◽  
Vol 11 (1) ◽  
pp. 130-139 ◽  
Author(s):  
Jihyung Hong ◽  
Diego Novick ◽  
William Montgomery ◽  
Jaume Aguado ◽  
Héctor Dueñas ◽  
...  

Objective: To examine whether painful physical symptoms (PPS) can be considered within the spectrum of depressive symptoms. Methods: Data for this post-hoc analysis were taken from a 6-month observational study mostly conducted in East Asia, Mexico, and the Middle East of 1,549 depressed patients without sexual dysfunction at baseline. Both explanatory and confirmatory factor analyses (EFA and CFA) were performed on the combined items of the 16-item Quick Inventory of Depressive Symptomatology Self-Report and the Somatic Symptom Inventory (seven pain-related items only). An additional second-order CFA was also conducted to examine an association between retained factors and the overall “depressive symptoms” factor. In addition, Spearman’s correlation was used to assess levels of correlation between retained factors and depression severity as well as quality of life. Results: Both EFA and CFA suggested and validated a four-factor solution, which included a pain factor. The other three factors identified were a mood/cognitive factor, a sleep disturbance factor, and an appetite/weight disturbance factor. All four factors were significantly associated with the overall factor of depression. They were also highly correlated to depression severity and quality of life (p<0.001 for all). The levels of correlations with the pain factor were generally greater than those with the appetite/weight factor and similar to those with the sleep factor. Conclusion: It may be reasonable to consider PPS within a broad spectrum of depressive symptoms. At least, they should be routinely assessed in patients with depression. Further research is warranted to validate these preliminary findings.


Psico-USF ◽  
2015 ◽  
Vol 20 (3) ◽  
pp. 505-515 ◽  
Author(s):  
Josieli Piovesan ◽  
Silvana Alba Scortegagna ◽  
Ana Carolina Bertoletti De Marchi

Abstract This study aimed to investigate the Quality of Life (QOL) and the presence of the depressive symptoms in mothers of individuals with Autism Spectrum Disorder (ASD). Participants included 40 women, between 28 and 72 years old, married, with medium-low income and education levels, and with children between 10 and 40 years old. The instruments used were a social demographic and health characterization questionnaire, the World Health Organization Quality of Life (WHOQOL-Bref) questionnaire, the Beck Depression Inventory and Beck Hopelessness Scale (BDI-II and BHS), and the Baptista Depression Scale Adult Version (EBADEP A). The quality of life and the presence of depressive symptoms in mothers did not show significant correlation with the child's age. However, there was high and negative correlation between the quality of life and high levels of depressive symptoms and moderate correlation between environment and income. It concludes the necessity of preventive and therapeutic interventions for these mothers.


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