scholarly journals Prevalence of severe adverse events in health professionals after receiving the first dose of the COVID-19 vaccination in Togo, March 2021

Author(s):  
Yao Rodion KONU ◽  
Fifonsi Gbeasor-Komlanvi ◽  
Mouhoudine Yerima ◽  
Arnold Junior Sadio ◽  
Martin Kouame Tchankoni ◽  
...  

Introduction: Covid-19 vaccines can cause adverse events (AE) that can lead to increased hesitation or fear of vaccination. This study aims at estimating the prevalence of severe adverse events (SAEs) and their associated factors among health professionals (HPs) vaccinated with COVISHIELD(TM) vaccine in Togo. Methods: A cross-sectional study was conducted from March 13th to 19th, 2021 in Togo among HPs who received the first dose of vaccine. An online self-administered questionnaire was used to collect data on sociodemographic characteristics and vaccination. SAEs were defined as one resulting in hospitalization, medical consultation, or inability to work the day following the administration of the vaccine. Regression analysis were performed to assess factors associated with SAEs. Results: A total of 1,639 HP (70.2% male) with a median age [IQR] of 32 years [27-40] participated. At least one AE was reported among 71.6% (95%CI= [69.3-73.8]). The most commonly reported AEs were pain at the injection site (91.0%), asthenia (74.3%), headache (68.7%), soreness (55.0%), and fever (47.5%). An increased libido was also reported in 3.0% of HP. Among HP who experienced AEs, 18.2% were unable to go to work the day after vaccination, 10.5% consulted a medical doctor, and 1.0% were hospitalized. The SAE prevalence was 23.8% (95%CI= [21.8-25.9]). Being <30 years (aOR=5.54; p<0.001), or 30-49 years (aOR=3.62; p<0.001) and being female (aOR=1.97; p<0.001) were associated with SAEs. Conclusion: Despite the occurrence of SAEs, current data collected in Togo about adverse events are reassuring with COVISHIELD(TM) vaccine and how they could be managed. Keywords: Severe adverse event, COVID-19, vaccine, prevalence, health professionals, Togo.

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Yao Rodion Konu ◽  
Fifonsi Adjidossi Gbeasor-Komlanvi ◽  
Mouhoudine Yerima ◽  
Arnold Junior Sadio ◽  
Martin Kouame Tchankoni ◽  
...  

Abstract Background The coronavirus disease 2019 (COVID-19) vaccines can cause adverse events that can lead to vaccine hesitancy. This study aims at estimating the prevalence of severe adverse events (SAEs) and their associated factors among health professionals vaccinated with ChAdOx1 nCoV-19 vaccine in Togo. Methods A cross-sectional study was conducted from March 13th to 19th, 2021 in Togo among health professionals who received the first dose of the vaccine. An online self-administered questionnaire was used to collect sociodemographic and vaccination data. SAEs were defined as one resulting in hospitalization, medical consultation, or inability to work the day following the administration of the vaccine. Data analysis were performed using R© 4.0.1 software, and a 5% significance level was considered. Results A total of 1,639 health professionals (70.2% male) with a median age of 32 (interquartile range: 27-40) were enrolled. At least one adverse event was reported among 71.6% of participants (95% CI = [69.3-73.8]). The most commonly reported adverse events were injection site pain (91.0%), asthenia (74.3%), headache (68.7%), soreness (55.0%), and fever (47.5%). An increased libido was also reported in 3.0% of participants. Of the participants who experienced adverse events, 18.2% were unable to go to work the day after vaccination, 10.5% consulted a medical doctor, and 1.0% were hospitalized. The SAEs’ prevalence was 23.8% (95% CI = [21.8-25.9]). Being <30 years (AOR = 5.54; p<0.001), or 30-49 years (AOR = 3.62; p<0.001) and being female (AOR = 1.97; p<0.001) were associated with SAEs. Conclusions High prevalence of SAEs have been observed in health professionals in Togo after ChAdOx1 nCoV-19 vaccination especially in young people and females. However, these data are reassuring as they inform on COVID-19 vaccines’ SAE management. Systematic prescription of antalgics or antipyretics could be proposed to young people who get vaccinated.


Author(s):  
Júlia Vasconcelos de Sá Alves ◽  
Waléria de Paula ◽  
Patrícia Ribeiro Rezende Netto ◽  
Brian Godman ◽  
Renata Cristina Rezende Macedo do Nascimento ◽  
...  

ABSTRACT Objective The aim was to evaluate the prevalence and factors associated with anxiety disorders among university students of health sciences at Federal University of Ouro Preto, Brazil. Methods A cross-sectional study between March to June 2019. Data were collected through a self-administered questionnaire including sociodemographic, academic, family and behavioral issues. The Beck Anxiety Inventory was used to assess anxiety. Estimates were obtained through the prevalence ratio and Poisson multivariate analysis. Results Four hundred and ninety-three students participated with a mean age of 23.1 and predominantly women (79.9%). All students had some degree of anxiety, with the frequency of the severe, moderate and mild forms being 28.0%, 29.8% and 27.0%, respectively. The factors associated with anxiety included having suffered psychological and/or physical violence in childhood, having suicidal thoughts, having a deceased parent, living with parents, being dissatisfied with the course and being in the exam period. Conclusions The prevalence of anxiety was high in our study and family problems prior to entering university seem to significantly influence the degree of anxiety, which may compromise the student’s academic and social performance.


2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Fiammetta Cosci ◽  
Vincenzo Zagà ◽  
Giuly Bertoli ◽  
Aquilele Campiotti

Tobacco use is dramatically increasing among youth. Growing attention has been addressed towards possible predictors of smoking in such a population. We evaluated a sample of Italian adolescents to verify whether adults and peers might influence their smoking status. Cross-sectional study was conducted in 16 schools of North Italy. Data were collected from 2001 to 2010 by means of a self-administered questionnaire on sociodemographic data and individual/social possible predictors of smoking. 2,444 students (56.7% boys; 43.3% girls; mean = 14.32 ± 1.384 years) were analysed. 607 (24.8%) were current smokers; 1,837 (75.2%) were nonsmokers. The presence of smokers in the family, seeing teachers who smoke, the influence of friends, and the feeling of inferiority were predictors of youth smoking as well as unawareness of nicotine dangerous action to health. Running the logistic multivariate analysis with all the variables listed above in the same model, the strongest predictors of smoking were as follows: being unaware that pipe/cigar is harmful to health as cigarettes; not knowing that passive smoking is harmful to the growth of children; having seen teachers smoking. The present findings help to identify the variables that might favour smoking in youth. Such variables should become the target of prevention programs.


2020 ◽  
Author(s):  
Maginsh Dahal ◽  
Raj Kumar Subedi ◽  
Sudip Khanal ◽  
Anup Adhikari ◽  
Manoj Sigdel ◽  
...  

Abstract Background: To determine the prevalence of premarital sex and its risk factors in Nepal.Methods: A cross-sectional study was carried out among adolescents in Nepal. A self-administered questionnaire was used to collect information from 6,147 unmarried adolescents. Random sampling by using a lottery method was applied to select 20 colleges from all three districts. All the students who were studying at those colleges were enrolled in the study. Simple and multivariate logistic regression analyses were carried out to analyse the associations of risk factors and premarital sex.Results: The prevalence of premarital sex was 38.1%. Male students were more likely to engage in premarital sex (adjusted odds ratio [AOR]=2.04, confidence interval [CI]=1.76-2.36) than female students. Alcohol consumption (AOR=1.26, CI=1.08-1.47), smoking (AOR=1.69, CI=1.41-2.02), drug use (AOR=1.85, CI=1.23-2.83), going to night clubs (AOR=1.46, CI=1.24-1.70), clothing style of girls AOR=1.35, CI=1.15-1.58), clothing style of boys (AOR=3.51, CI=2.74-4.53), and unmarried friends having sex (AOR= 1.51, CI=1.31-1.73) were found to be major influencing factors for premarital sex. Moreover, students who had never received sex education were 2.92 times more likely to engage in premarital sex (CI=2.22-3.85) than those who had previously received sex education.Conclusions: We found several risk factors associated with premarital sex in Nepal. Preventing premarital sex may require the promotion of sex education.


2020 ◽  
Vol 19 (3) ◽  
pp. 36-67
Author(s):  
Nanete Caroline da Costa Prado ◽  
Rebecca Stefany da Costa Santos ◽  
Romanniny Hévillyn Silva Costa Almino ◽  
Dhyanine Morais de Lima ◽  
Sylvia Silva de Oliveira ◽  
...  

Objetivo: Identificar los factores asociados con la aparición de eventos adversos en el catéter de inserción central periférica en recién nacidos.Métodos: Un estudio transversal con un enfoque cuantitativo realizado en una Unidad de Cuidados Intensivos Neonatales de un hospital de maternidad de referencia en atención materna e infantil de alto riesgo en el noreste de Brasil. Muestra de 108 neonatos recolectados de febrero a noviembre de 2016.Resultados: La prevalencia de eventos adversos en los recién nacidos fue del 53,70%, asociada a las siguientes variables: sexo masculino (p = 0,033), peso inferior a 2500 gramos (p = 0,003), inserción después de 48 horas (p = 0,027), más de tres intentos de punción (p = 0,024), dificultad de progresión del catéter (p = 0,040), presencia de intercurrencias durante la inserción del catéter (p = 0,027), sobre dos cambios de apósito = 0.009) y ubicación no central del dispositivo (p = 0.042).Conclusión: Los resultados indican la necesidad de estrategias para la prevención de eventos adversos, con énfasis en la educación continua y el mejoramiento de habilidades en la gestión de este dispositivo. Objective: To identify the factors associated with the occurrence of adverse events by a peripherally inserted central catheter in newborns. Methods: A quantitative, cross-sectional study carried out in the Neonatal Intensive Care Unit of a reference maternity hospital in high-risk maternal and child care in Northeast Brazil. The sample of 108 neonates was collected from February to November 2016. Results: The prevalence of adverse events in newborns was 53.70%, associated with the following variables: male gender (p=0.033), weight below 2500 grams (p=0.003), insertion performed after 48 hours of life (p=0.027), more than three puncture attempts (p=0.024), difficulty in inserting the catheter (p=0.040), intercurrence during catheter insertion (p=0.027), over two dressing changes (p=0.009), and non-central position of the device (p=0.042). Conclusion: The results indicate the need for strategies to prevent adverse events, with emphasis on continuing education and on the improvement of skills regarding the use of this device.


2019 ◽  
Vol 185 (19) ◽  
pp. 600-600 ◽  
Author(s):  
Belén Barrero-Domínguez ◽  
Inmaculada Luque ◽  
Belen Huerta ◽  
Jaime Gomez-Laguna ◽  
Ángela Galán-Relaño ◽  
...  

BackgroundParatuberculosis (PTB) is a chronic, enteric wasting disease of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP), with a worldwide distribution. Andalusia, located in southern Spain, is one of the European regions with the highest goat census and the highest milk production; however, current data on the prevalence of MAP in this species are not available.MethodsA cross-sectional study was performed to determine the seroprevalence and risk factors associated with PTB in dairy goat flocks from southern Spain. A total of 3312 serum samples were collected from 48 flocks located in three different geographical areas. Health and productive parameters were surveyed during the visit to the herds.ResultsA total of 511 goats were seropositive, with overall true seroprevalence of 22.54 per cent (95 per cent confidence interval (CI95) 21.12–23.97). Of the goat herds, 87.50 per cent (CI9578.14–96.98) were seropositive. The intraherd seroprevalence was 25.43±31.71, distributed as follows: 22 flocks with a seroprevalence under 10 per cent; 18 flocks between 10 per cent and 50 per cent; and eight flocks with a frequency over 50 per cent. Multivariate logistic regression showed significant association between PTB seropositivity and the following variables: intensive production system, lack of management by batches, inappropriate ventilationandseropositivity tocaprinearthritisencephalitisvirus (CAEV).ConclusionsThe results indicate a widespread PTB infection in goat herds in southern Spain. Thus, control programmes must include management and sanitary measures to reduce the prevalence. Further experimental studies are necessary to determine the influence of CAEV-PTB coinfection on immune status.


2009 ◽  
Vol 21 (3) ◽  
pp. 252-258 ◽  
Author(s):  
Zairina Abdul Rahman ◽  
Abdul Sallam Atiya

An analytical cross-sectional study was carried out to determine the prevalence of work-related upper limbs symptoms (WRULS) among office workers and factors associated with it. A self-administered questionnaire was used to collect the information. A total of 463 (87.7%) office workers from selected government agencies participated in this study. The mean age of the respondents was 34.1 years (range = 18-55 years). Majority (91.6%) were Malay and female (72.8%), and 58.1% were from clerical group. Mean duration of work was 8.7 years. This study found that prevalence of WRULS was 33.0% (95% CI [confidence interval] = 28.8%, 37.3%). Computer users at work had 2.0 (95% CI = 1.1, 3.4) higher odds ratio of developing WRULS and those who used it for 5 hours and more per day had 7.5 (95% CI = 2.3, 24.2) higher odds ratio of developing WRULS. Hand-intensive hobbies and higher education were also found to be associated with WRULS.


Author(s):  
Ram Lochan Yadav ◽  
Laxmi Kumari Yadav ◽  
Rosan Churasiya ◽  
Md. Nazrul Islam

Background: Health professionals, the frontline fighters, are under high risk of being infected with a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Many health workers in the world, including Nepal, have lost their lives in fighting with COVID-19. Thus, we assessed the knowledge, attitude, risk, and fear among health professionals towards COVID-19 and evaluated their satisfaction with local and governmental policies of Nepal. Methods: A self-administered questionnaire-based descriptive cross-sectional study included 150 (male-44% and female-56%) health professionals with mean age 26.14±6.092 years working at Chitwan Medical College, Nepal. The questionnaire included 40 statements having four categories to assess 1) the participant’s knowledge about COVID-19, 2) the risk and attitude, 3) their fears, and 4) stake holder’s role in encouraging health professionals to allay their fears and avert negative attitudes.


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Jember Azanaw ◽  
Mulat Gebrehiwot ◽  
Henok Dagne

Abstract Objective The primary objective of this study was to assess factors associated with food safety practices among food handlers in Gondar city food and drinking establishments. The facility-based cross-sectional study was undertaken from March 3 to May 28, 2018, in Gondar city. Simple random sampling method was used to select both establishments and the food handlers. The data were collected through face-to-face interview using pre-tested Amharic version of the questionnaire. Data were entered and coded into Epi info version 7.0.0 and exported to SPSS version 22 for analysis. Results One hundred and eighty-eight (49.0%) had good food handling practice out of three hundred and eighty-four food handlers. Marital status (AOR: 0.36, 95% CI 0.05, 0.85), safety training (AOR: 4.01, 95% CI 2.71, 9.77), supervision by health professionals (AOR: 4.10, 95% CI 1.71, 9.77), routine medical checkup (AOR: 8.80, 95% CI 5.04, 15.36), and mean knowledge (AOR: 2.92, 95% CI 1.38, 4.12) were the factors significantly associated with food handling practices. The owners, managers and local health professionals should work on food safety practices improvement.


1970 ◽  
Vol 28 (6) ◽  
Author(s):  
Mestawet Getachew ◽  
Tsegaye Tewelde

BACKGROUND: Cosmetics is applied to human body for cleansing, beautifying, promoting attractiveness or altering appearance. Cosmetics is causing alarming adverse events to its users, yet evidence about its magnitude and cosmetic use among female employees in Ethiopia is limited. Therefore, this study was aimed at determining cosmetic use and its adverse events among female employees of Jimma University.METHOD: A cross-sectional study was done among female employees from December 2016 to January 2017. Samples of 426 participants were selected using stratified simple random sampling from all colleges, and data were collected using self-administered questionnaire. Descriptive statistics was used to compute proportions and logistic regression to assess the determinants of cosmetics-related adverse events.RESULTS: A total of 387 females were participated, making a 90.8% response rate. The majority (80.1%) were using at least one cosmetic product, and 39.0% of them were between 25-29 years. The majority (86.6%) of the respondents used toothpaste, lotion, lipstick, or eye makeup. Cosmetics related adverse events were experienced by 19.0% of the respondents primarily on face and hairs. Lotion and hair cosmetics were the primary perceived causes of adverse events. Employees who had monthly income between 1000 and 3000 ETB (AOR=3.4; 95% CI: 1.4-8.4), above 3000 ETB (AOR=4.7; 95% CI: 1.8-12.2) and those who used traditional cosmetics (AOR=4.5; 95% CI: 2.1-9.6) were more likely to develop adverse events.CONCLUSION: A significant proportion of the users suffered from cosmetics related adverse events. The female employees have to be aware of the rational cosmetics utilization practices to minimize adverse events. 


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