scholarly journals An Atomic Approach to the Design and Implementation of a Research Data Warehouse

2021 ◽  
Author(s):  
Shyam Visweswaran ◽  
Brian McLay ◽  
Nickie Capella ◽  
Michele Morris ◽  
John T Milnes ◽  
...  
Keyword(s):  
Data Warehouse ◽  
Identity Management ◽  
Medical Center ◽  
Research Data ◽  
Patient Data ◽  
Information Storage ◽  
Research Network ◽  
Multiple Sources ◽  
University Of Pittsburgh ◽  
The University

Objective As a long-standing Clinical and Translational Science Awards (CTSA) Program hub, the University of Pittsburgh and the University of Pittsburgh Medical Center (UPMC) developed and implemented a modern research data warehouse (RDW) to efficiently provision electronic patient data for clinical and translational research. Methods Because UPMC is one of the largest health care systems in the US with multiple vendors' electronic health record (EHR) systems, we designed and implemented an RDW named Neptune to serve the specific needs of our CTSA. Neptune uses an atomic design where data is stored at a high level of granularity as represented in source systems. Neptune contains robust patient identity management tailored for research; integrates patient data from multiple sources, including EHRs, health plans, and research studies; and includes knowledge for mapping to standard terminologies. Neptune enables efficient provisioning of data to large analytics-oriented data models and to individual investigators. Results Neptune contains data for more than 5 million patients longitudinally organized as HIPAA Limited Data with dates and includes structured EHR data, clinical documents, health insurance claims, and research data. Neptune is used as a source for patient data for hundreds of IRB-approved research projects by local investigators and for national projects such as the Accrual to Clinical Trials (ACT) network, the All of Us Research Program, and the National Patient-Centered Clinical Research Network. Discussion The design of Neptune was heavily influenced by the large size of UPMC, the varied data sources, and the rich partnership between the University and the healthcare system. It features several desiderata of an RDW, including robust protected health information management, an extensible information storage model, and binding to standard terminologies at the time of data delivery. It also includes several unique aspects, including the physical warehouse straddling the University of Pittsburgh and UPMC networks and management under a HIPAA Business Associates Agreement.

The Center for International Biomedical Communications Research

1966 ◽  
Vol 05 (03) ◽  
pp. 142-146
Author(s):  
A. Kent ◽  
P. J. Vinken
Keyword(s):  
Information Needs ◽  
English Language ◽  
Medical Information ◽  
Biomedical Literature ◽  
Information Storage ◽  
Control Mechanisms ◽  
University Of Pittsburgh ◽  
The World ◽  
The University ◽  
Excerpta Medica Foundation

A joint center has been established by the University of Pittsburgh and the Excerpta Medica Foundation. The basic objective of the Center is to seek ways in which the health sciences community may achieve increasingly convenient and economical access to scientific findings. The research center will make use of facilities and resources of both participating institutions. Cooperating from the University of Pittsburgh will be the School of Medicine, the Computation and Data Processing Center, and the Knowledge Availability Systems (KAS) Center. The KAS Center is an interdisciplinary organization engaging in research, operations, and teaching in the information sciences.Excerpta Medica Foundation, which is the largest international medical abstracting service in the world, with offices in Amsterdam, New York, London, Milan, Tokyo and Buenos Aires, will draw on its permanent medical staff of 54 specialists in charge of the 35 abstracting journals and other reference works prepared and published by the Foundation, the 700 eminent clinicians and researchers represented on its International Editorial Boards, and the 6,000 physicians who participate in its abstracting programs throughout the world. Excerpta Medica will also make available to the Center its long experience in the field, as well as its extensive resources of medical information accumulated during the Foundation’s twenty years of existence. These consist of over 1,300,000 English-language _abstract of the world’s biomedical literature, indexes to its abstracting journals, and the microfilm library in which complete original texts of all the 3,000 primary biomedical journals, monitored by Excerpta Medica in Amsterdam are stored since 1960.The objectives of the program of the combined Center include: (1) establishing a firm base of user relevance data; (2) developing improved vocabulary control mechanisms; (3) developing means of determining confidence limits of vocabulary control mechanisms in terms of user relevance data; 4. developing and field testing of new or improved media for providing medical literature to users; 5. developing methods for determining the relationship between learning and relevance in medical information storage and retrieval systems’; and (6) exploring automatic methods for retrospective searching of the specialized indexes of Excerpta Medica.The priority projects to be undertaken by the Center are (1) the investigation of the information needs of medical scientists, and (2) the development of a highly detailed Master List of Biomedical Indexing Terms. Excerpta Medica has already been at work on the latter project for several years.

A TEACHING PROGRAM IN COMMUNITY PEDIATRICS

PEDIATRICS ◽  
1960 ◽  
Vol 25 (2) ◽  
pp. 336-339
Author(s):  
Kenneth D. Rogers
Keyword(s):  
Medical Center ◽  
Group Discussion ◽  
Outpatient Service ◽  
Field Trip ◽  
Teaching Program ◽  
Exceptional Children ◽  
University Of Pittsburgh ◽  
School Of Medicine ◽  
Informal Discussion ◽  
The University

AT THE School of Medicine of the University of Pittsburgh, the Department of Pediatrics has organized a series of field experiences intended to acquaint future physicians with programs and facilities outside the confines of the Medical Center which are concerned directly or indirectly with the health and welfare of normal and exceptional children. During their pediatric outpatient service, senior medical students in groups of six to eight spend 6 half-days in "community pediatric" training. Each student is loaned a collection of selected reprints, booklets and mimeographed material pertinent to the areas covered in the community experiences. They are urged to read the appropriate material before each field trip in order that their observations may be meaningful and productive. Additional preparation is given at the visit site by approximately an hour's group discussion of the general area to be covered, specific items to be noted, and questions to be considered during the experience. No attempt is made to cover all aspects of the program being viewed. Informal discussion and interpretation are maintained by the instructor throughout the field trip.

Implementation of the Acute Care Nurse Practitioner Role

1994 ◽  
Vol 5 (3) ◽  
pp. 404-407
Author(s):  
Lynn A. Kelso ◽  
Lori M. Massaro
Keyword(s):  
Acute Care ◽  
Nurse Practitioners ◽  
Nurse Practitioner ◽  
Medical Center ◽  
Care Nurse ◽  
University Of Pittsburgh ◽  
Acute Care Nurse Practitioner ◽  
The University ◽  
Pittsburgh Medical ◽  
Practitioner Role

In this article, the experiences of two new acute care nurse practitioners working at the University of Pittsburgh Medical Center arc described. Included are the experiences they encountered in initiating the role and some of the responsibilities they assumed.

Short-Term Results of Treating Primary and Recurrent Anal Fistulas with a Novel Extracellular Matrix Derived from Porcine Urinary Bladder

2015 ◽  
Vol 81 (5) ◽  
pp. 498-502 ◽  
Author(s):  
Tara Iorio ◽  
David Blumberg
Keyword(s):  
Urinary Bladder ◽  
Medical Center ◽  
Experimental Studies ◽  
Great Promise ◽  
Anal Fistulas ◽  
Short Term ◽  
University Of Pittsburgh ◽  
Standardized Protocol ◽  
Promising Treatment ◽  
The University

Anal fistulas are difficult to treat because they are often recalcitrant to medical therapies and surgical treatment may lead to significant morbidities. A recent novel biologically derived graft from porcine urinary bladder (MatriStem™) has shown great promise in experimental studies of tissue regeneration in diverse tissues. The objectives of this study were to evaluate the safety and short-term efficacy of MatriStem for treatment of anal fistulas. This was a retrospective study of patients treated from January 3, 2012 to March 3, 2014 at the University of Pittsburgh Medical Center. MatriStem was used to treat patients with anal fistulas by implanting it uniformly with a single application in all patients using a standardized protocol. Data were collected retrospectively from hospital records and office charts. Nineteen fistulas were treated with MatriStem. There were no adverse complications. Overall efficacy of MatriStem was 79 per cent with healing occurring in a mean time of 17 days and mean follow-up of seven months (range 1–26 months). MatriStem was effective in healing in 75 per cent of primary anal fistulas and 86 per cent of recurrent fistulas. MatriStem seems to be a safe and promising treatment for primary and recurrent anal fistulas, and warrants further study and clinical trials to substantiate widespread clinical use.

scholarly journals Meeting Resident Scholarly Activity Requirements Through a Longitudinal Quality Improvement Curriculum

2015 ◽  
Vol 7 (1) ◽  
pp. 86-90 ◽  
Author(s):  
Madeline Simasek ◽  
Stephanie L. Ballard ◽  
Phillip Phelps ◽  
Rowena Pingul-Ravano ◽  
N. Randall Kolb ◽  
...  
Keyword(s):  
Quality Improvement ◽  
Family Medicine ◽  
Literature Review ◽  
Work Group ◽  
Medical Center ◽  
Care Program ◽  
Scholarly Activity ◽  
University Of Pittsburgh ◽  
Outpatient Practice ◽  
The University

Abstract Background Quality improvement (QI) skills are learned during residency, yet there are few reports of the scholarly activity outcomes of a QI curriculum in a primary care program. Intervention We examined whether scholarly activity can result from a longitudinal, experiential QI curriculum that involves residents, clinic staff, and faculty. Methods The University of Pittsburgh Medical Center Shadyside Family Medicine Residency implemented a required longitudinal outpatient practice improvement rotation (LOPIR) curriculum in 2005. The rotation format includes weekly multidisciplinary work group meetings alternating with resident presentations delivered to the entire program. Residents present the results of a literature review and provide 2 interim project updates to the residency. A completed individual project is required for residency graduation, with project results presented at Residency Research Day. Scholarly activity outcomes of the curriculum were analyzed using descriptive statistics. Results As of 2014, 60 residents completed 3 years of the LOPIR curriculum. All residents satisfied the 2014 Accreditation Council for Graduate Medical Education (ACGME) scholarly activity and QI requirements with a literature review presentation in postgraduate year 2, and the presentation of a completed QI project at Residency Research Day. Residents have delivered 83 local presentations, 13 state/regional presentations, and 2 national presentations. Residents received 7 awards for QI posters, as well as 3 grants totaling $21,639. The educational program required no additional curriculum time, few resources, and was acceptable to residents, faculty, and staff. Conclusions LOPIR is an effective way to meet and exceed the 2014 ACGME scholarly activity requirements for family medicine residents.

Transition to an Individual-Room NICU Design: Process and Outcome Measures

2008 ◽  
Vol 27 (5) ◽  
pp. 299-305 ◽  
Author(s):  
Cheryl Milford ◽  
Barbara Zapalo ◽  
Glenda Davis
Keyword(s):  
Design Process ◽  
Neonatal Intensive Care ◽  
Best Practice ◽  
Medical Center ◽  
Outcome Data ◽  
University Of Pittsburgh ◽  
Developmentally Supportive Care ◽  
Guidelines And Recommendations ◽  
Design And Practice ◽  
The University

Redesign of a neonatal intensive care unit is a major budget undertaking, demanding accountability for its equipment and feasibility of design. It must be philosophically based and driven by research supporting best practice. The NICU at the Magee-Womens Hospital of the University of Pittsburgh Medical Center, a Level III, 74-bed unit, has made the change from a ward design to an individual-room design suitable for family-centered, developmentally supportive care. This article presents the design process as it occurred. Unique to this process are the involvement of NICU-graduate families and the use of transition teams. Guidelines and recommendations are offered to others interested in designing and practicing in an individual-room NICU. Outcome data demonstrate staff adjustment to the new design and practice model. A comparison of this NICU design is made with the Recommended Standards for Newborn ICU Design.

scholarly journals The evolution of a clinical registry during 25 years of experience with Gamma Knife radiosurgery in Pittsburgh

2013 ◽  
Vol 34 (1) ◽  
pp. E4 ◽  
Author(s):  
Oren Berkowitz ◽  
Douglas Kondziolka ◽  
David Bissonette ◽  
Ajay Niranjan ◽  
Hideyuki Kano ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Patient Outcomes ◽  
Medical Center ◽  
Gamma Knife Radiosurgery ◽  
Study Patient ◽  
Anatomical Site ◽  
University Of Pittsburgh ◽  
Database Technology ◽  
The University ◽  
Pittsburgh Medical

Object The first North American 201 cobalt-60 source Gamma Knife surgery (GKS) device was introduced at the University of Pittsburgh Medical Center in 1987. The introduction of this innovative and largely untested surgical procedure prompted the desire to study patient outcomes and evaluate the effectiveness of this technique. The parallel advances in computer software and database technology led to the development of a registry to track patient outcomes at this center. The purpose of this study was to describe the registry's evolution and to evaluate its usefulness. Methods A team was created to develop a software database and tracking system to organize and retain information on the usage of GKS. All patients undergoing GKS were systematically entered into this database by a clinician familiar with the technology and the clinical indications. Information included patient demographics and diagnosis as well as the anatomical site of the target and details of the procedure. Results There are currently 11,738 patients in the database, which began to be used in August 1987. The University of Pittsburgh Medical Center has pioneered the evaluation and publication of the GKS technique and outcomes. Data derived from this computer database have facilitated the publication of more than 400 peer-reviewed manuscripts, more than 200 book chapters, 8 books, and more than 300 published abstracts and scientific presentations. The use of GKS has become a well-established surgical technique that has been performed more than 700,000 times around the world. Conclusions The development of a patient registry to track and analyze the use of GKS has given investigators the ability to study patient procedures and outcomes. The future of clinical medical research will rely on the ability of clinical centers to store and to share information.

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