A decade of Acceptability Research with Adolescents in Africa: Systematic review and evidence map

Interventions aimed at improving adolescent developmental outcomes are more likely to be successful if the young people they target find them acceptable. However, no standard definitions or indicators exist to assess acceptability, acceptability research with adolescents in LMICs is still limited, and no known reviews synthesise the evidence from Africa. We conducted a systematic review of peer-reviewed studies assessing intervention acceptability with young adults (aged 10-24) in Africa, published between January 2010 and June 2020. This paper maps and qualitatively synthesizes the scope, characteristics, and findings of these studies, including definitions of acceptability, methods used, the type and objectives of interventions assessed, and overall findings on adolescent acceptability. The review was carried out in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Key word searches generated 4692 unique records and 55 final eligible studies, assessing 60 interventions. Most studies were conducted in Southern Africa, of which 32 jointly in South Africa and Uganda. The majority of interventions assessed for acceptability could be classified as HIV or HPV vaccine interventions (10), E-health (10), HIV testing interventions (8), support group interventions (7) and contraceptive interventions (6). The objectives of most interventions were linked to SDG3, specifically to HIV and sexual and reproductive health. Acceptability was overall high among these published studies. 22 studies provided reasons for acceptability or lack thereof, some specific to particular types of interventions and others common across intervention types. Our review exposes considerable scope for future acceptability research and review work. This should include: extending acceptability research beyond the health (and particularly HIV) sector and to regions in Africa where this type of research is still scarce; including adolescents earlier, and potentially throughout the intervention process; further conceptualising the construct of acceptability among adolescents and beyond, and examining the relationship between acceptability and uptake.

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Not Only Mania or Depression: Mixed States/Mixed Features in Paediatric Bipolar Disorders

Brain Sciences ◽

10.3390/brainsci11040434 ◽

2021 ◽

Vol 11 (4) ◽

pp. 434

Author(s):

Delfina Janiri ◽

Eliana Conte ◽

Ilaria De Luca ◽

Maria Velia Simone ◽

Lorenzo Moccia ◽

...

Keyword(s):

Systematic Review ◽

Bipolar Disorders ◽

Prevalence Rates ◽

Mixed States ◽

Total Patient ◽

Hyperactivity Disorder ◽

Mixed Features ◽

Paediatric Age ◽

Meta Analyses ◽

The Relationship

Background: early onset is frequent in Bipolar Disorders (BDs), and it is characterised by the occurrence of mixed states (or mixed features). In this systematic review, we aimed to confirm and extend these observations by providing the prevalence rates of mixed states/features and data on associated clinical, pharmacological and psychopathological features. Methods: following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched from inception to 9 February 2021 for all studies investigating mixed states/mixed features in paediatric BD. Data were independently extracted by multiple observers. The prevalence rates of mixed states/features for each study were calculated. Results: eleven studies were included in our review, involving a total patient population of 1365 individuals. Overall, of the patients with paediatric age BD, 55.2% had mixed states/features (95% CI 40.1–70.3). Children with mixed states/features presented with high rates of comorbidities, in particular, with Attention Deficit Hyperactivity Disorder (ADHD). Evidences regarding the psychopathology and treatment response of mixed states/features are currently insufficient. Conclusions: our findings suggested that mixed states/features are extremely frequent in children and adolescents with BD and are characterised by high levels of comorbidity. Future investigations should focus on the relationship between mixed states/features and psychopathological dimensions as well as on the response to pharmacological treatment.

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Meditation: Evidence Map of Systematic Reviews

Frontiers in Public Health ◽

10.3389/fpubh.2021.742715 ◽

2021 ◽

Vol 9 ◽

Author(s):

Caio Fábio Schlechta Portella ◽

Ricardo Ghelman ◽

Veronica Abdala ◽

Mariana Cabral Schveitzer ◽

Rui Ferreira Afonso

Keyword(s):

Health Outcomes ◽

Systematic Reviews ◽

Well Being ◽

Complementary Therapy ◽

Evidence Map ◽

Confidence Levels ◽

Positive Effects ◽

Key Word ◽

Meta Analyses

Study Basis: This evidence map presents a summary of studies that addressed the effects of meditation on various clinical and health conditions. Meditation is a contemplative practice that has been used for the promotion of health, and the treatment of different conditions.Method: The study is based on the search of four electronic databases for the period 1994-November 2019 and includes systematic reviews, meta-analyses, meta-syntheses, and integrative reviews. 3iE evidence gap map was the methodology of choice, and AMSTAR 2 was used for the analyses. Tableau was used to graphically display the confidence level, number of reviews, health outcomes, and intervention effects.Results: This map encompasses 191 studies, with Mindfulness being the key word that retrieved the highest number of results. Several meditation techniques were evaluated in different contexts, and the confidence levels of 22 studies were high, 84 were moderate, and 82 were low. Two 2 meta-syntheses and 1 integrative review were also included. Most of the studies reported positive effects and a beneficial potential of the practice of meditation. Health outcomes were divided into five groups out of which mental health and vitality, and well-being and quality of life stood out with the largest number of studies.Conclusions: Meditation has been applied in different areas. This Evidence Map intends to be an easy visual tool to access valuable evidence-based information on this complementary therapy for patients, health professionals, and managers.

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Psychiatric Manifestations of Coeliac Disease, a Systematic Review and Meta-Analysis

Nutrients ◽

10.3390/nu12010142 ◽

2020 ◽

Vol 12 (1) ◽

pp. 142 ◽

Cited By ~ 3

Author(s):

Emma Clappison ◽

Marios Hadjivassiliou ◽

Panagiotis Zis

Keyword(s):

Systematic Review ◽

Eating Disorders ◽

Coeliac Disease ◽

Psychiatric Disorders ◽

Meta Analysis ◽

Hyperactivity Disorder ◽

Increased Risk ◽

Meta Analyses ◽

Psychiatric Manifestations ◽

The Relationship

Background: Coeliac disease (CD) is increasingly prevalent and is associated with both gastrointestinal (GI) and extra-intestinal manifestations. Psychiatric disorders are amongst extra-intestinal manifestations proposed. The relationship between CD and such psychiatric disorders is not well recognised or understood. Aim: The aim of this systematic review and meta-analysis was to provide a greater understanding of the existing evidence and theories surrounding psychiatric manifestations of CD. Methodology: An online literature search using PubMed was conducted, the prevalence data for both CD and psychiatric disorders was extracted from eligible articles. Meta analyses on odds ratios were also performed. Results: A total of 37 articles were included in this review. A significant increase in risk was detected for autistic spectrum disorder (OR 1.53, 95% CI 1.24–1.88, p < 0.0001), attention deficit hyperactivity disorder (OR 1.39, 95% CI 1.18–1.63, p < 0.0001), depression (OR 2.17, 95% CI 2.17–11.15, p < 0.0001), anxiety (OR 6.03, 95% CI 2.22–16.35, p < 0.0001), and eating disorders (OR 1.62, 95% CI 1.37–1.91, p < 0.00001) amongst the CD population compared to healthy controls. No significant differences were found for bipolar disorder (OR 2.35, 95% CI 2.29–19.21, p = 0.43) or schizophrenia (OR 0.46, 95% CI 0.02–10.18, p = 0.62). Conclusion: CD is associated with an increased risk of depression, anxiety, eating disorders as well as ASD and ADHD. More research is required to investigate specific biological explanations as well as any effect of gluten free diet.

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The relationship between zinc intake and indices of cognitive function: A systematic review and meta-analyses

Proceedings of The Nutrition Society ◽

10.1017/s0029665113002358 ◽

2013 ◽

Vol 72 (OCE4) ◽

Author(s):

M. Warthon-Medina ◽

S. Dillon ◽

V. Hall Moran ◽

A. L. Stammers ◽

P. Qualter ◽

...

Keyword(s):

Systematic Review ◽

Cognitive Function ◽

Zinc Intake ◽

Meta Analyses ◽

The Relationship

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Human Rights and Socio-Environmental Conflicts of Mining in Mexico: A Systematic Review

Sustainability ◽

10.3390/su14020769 ◽

2022 ◽

Vol 14 (2) ◽

pp. 769

Author(s):

Abraham Camacho-Garza ◽

Otilio A. Acevedo-Sandoval ◽

Elena Ma. Otazo-Sánchez ◽

Alma D. Roman-Gutiérrez ◽

Francisco Prieto-García

Keyword(s):

Systematic Review ◽

Human Rights ◽

Environmental Damage ◽

Critical Research ◽

Environmental Conflicts ◽

Systematic Analysis ◽

Mining Areas ◽

Private Interests ◽

Meta Analyses ◽

The Relationship

Socio-environmental conflicts are situations that exemplify human rights transgressions caused by extractive activities. These are present in developing countries where extractivism, imperialism, and colonialism paradigms prevail. In the context of Mexico, criminalization, violence, and the absence of rule of law promote these conflicts, frequently aggravated by involvement with private interests. In the last 20 years, the relationship between human rights in the mining sector and its impact on the environment has been a critical research subject. This paper aims to carry out a systematic review to analyze human rights transgressions related to the mining industry’s impact in Mexico, and identify factors causing socio-environmental conflicts. The current study shows a systematic analysis based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodology. This method contributed to the collection of references that describe conflicts due to human rights transgressions and environmental damage in mining areas in Mexico. Human rights transgressions caused by mining in a Mexican context demonstrate the inability of the state to stop the increase in socio-environmental conflicts and its lack of concern towards preventing damage to the environment.

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Prognostic value of miR-21 for prostate cancer: a systematic review and meta-analysis

Bioscience Reports ◽

10.1042/bsr20211972 ◽

2021 ◽

Author(s):

MY Cynthia Stafford ◽

Colin E Willoughby ◽

Colum P Walsh ◽

Declan J McKenna

Keyword(s):

Prostate Cancer ◽

Systematic Review ◽

Disease Progression ◽

Poor Prognosis ◽

Meta Analysis ◽

Risk Groups ◽

Cochrane Library ◽

Clinical Biomarker ◽

Meta Analyses ◽

The Relationship

Elevated levels of miR-21 expression are associated with many cancers, suggesting it may be a promising clinical biomarker. In prostate cancer (PCa), however, there is still no consensus about the usefulness of miR-21 as an indicator of disease progression. This systematic review and meta-analysis was conducted to investigate the value of miR-21 expression as a prognostic measurement in PCa patients. Medline (Ovid), EMBASE, Web of Science, Scopus and Cochrane Library databases were systematically searched for relevant publications between 2010 to 2021. Studies exploring the relationship between miR-21 expression, PCa prognosis and clinicopathological factors were selected for review. Those reporting hazard ratio (HR) and 95% confidence intervals (CIs) were subject to meta-analyses. Fixed-effect models were employed to calculated pooled HRs and 95% CIs. Risk of bias in each study was assessed using QUIPS tool. Certainty of evidence in each meta-analysis was assessed using GRADE guidelines. A total of 64 studies were included in the systematic review. Of these, 11 were eligible for inclusion in meta-analysis. Meta-analyses revealed that high miR-21 expression was associated with poor prognosis: HR=1.58 (95% CI=1.19-2.09) for biochemical recurrence, MODERATE certainty; HR=1.46 (95% CI=1.06-2.01) for death, VERY LOW certainty; and HR=1.26 (95% CI=0.70-2.27) for disease progression, VERY LOW certainty. Qualitative summary revealed elevated miR-21 expression was significantly positively associated with PCa stage, Gleason score and risk groups. This systematic review and meta-analysis suggests that elevated levels of miR-21 are associated with poor prognosis in PCa patients. miR-21 expression may therefore be a useful prognostic biomarker in this disease.

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Adolescent Sport Participation and Symptoms of Anxiety and Depression: A Systematic Review and Meta-Analysis

Journal of Sport and Exercise Psychology ◽

10.1123/jsep.2019-0235 ◽

2020 ◽

Vol 42 (3) ◽

pp. 201-218

Author(s):

Michael J. Panza ◽

Scott Graupensperger ◽

Jennifer P. Agans ◽

Isabelle Doré ◽

Stewart A. Vella ◽

...

Keyword(s):

Systematic Review ◽

Sport Participation ◽

Causal Effect ◽

Meta Analysis ◽

Effect Sizes ◽

Anxiety And Depression ◽

Organized Sport ◽

Protective Environment ◽

Meta Analyses ◽

The Relationship

Sport may protect against symptoms of mental disorders that are increasingly prevalent among adolescents. This systematic review explores the relationship between adolescent organized sport participation and self-reported symptoms of anxiety and depression. From 9,955 records screened, 29 unique articles were selected that included 61 effect sizes and 122,056 participants. Effects were clustered into four categories based on the operationalization of sport involvement: absence or presence of involvement, frequency of involvement, volume of involvement, and duration of participation. Results from the random-effects meta-analyses indicated that symptoms of anxiety and depression were significantly lower among sport-involved adolescents than in those not involved in sport, although this effect size was small in magnitude. Meta-regression was used to identify how age and sex explained heterogeneity in effects. Although these results do not signify a causal effect, they do support theorizing that sport participation during adolescence may be a protective environment against anxiety and depressive symptoms.

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Uso de implantes dentais em pacientes com bruxismo

Full Dentistry in Science ◽

10.24077/2021;1246-124130 ◽

2021 ◽

Vol 12 (46) ◽

pp. 124-130

Author(s):

Menandro dos Santos Garcia ◽

Ricardo Jun Furuyama ◽

Dalter Silva Favarete ◽

Nasser Hussein Fares

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Literature Review ◽

Dental Implant ◽

Temporomandibular Disorders ◽

Implant Failure ◽

Potential Risk Factors ◽

Occlusal Vertical Dimension ◽

Meta Analyses ◽

The Relationship

Dentition with severe wear in patients stricken by bruxism is a challenge due to loss of dental structure and occlusal vertical dimension and the temporomandibular implications. Bruxism is presented as a contraindication in cases of dental implants. This systematic review was carried out by examining the electronic literature available at PubMed and Google Scholar from 2010 to 2020 in Portuguese, English and Spanish languages. The review details the relationship between bruxism and dental implant failure in contrast to temporomandibular disorders, presenting the following conclusions: a) bruxism is a contributing factor to the occurrence of technical / biological complications of the dental implant and plays an important role in the failure of the dental implant; b) the anamnesis must be detailed to confirm sleep or day bruxism; c) the control of bruxism through the use of occlusal stabilization device may provide relief in the implants region and it is highly recommended. The aim of this literature review was to summarize the influences of different potential risk factors on the incidence of late dental implant failure. The protocol for this systematic review was prepared and implemented based on PRISMA guideline – Preferred Reporting Items for Systematic Reviews and Meta-Analyses.

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Obesity and Natural Spaces in Adults and Older People: A Systematic Review

Journal of Physical Activity and Health ◽

10.1123/jpah.2020-0589 ◽

2021 ◽

pp. 1-14

Author(s):

Andreia Teixeira ◽

Ronaldo Gabriel ◽

Luis Quaresma ◽

Ana Alencoão ◽

José Martinho ◽

...

Keyword(s):

Systematic Review ◽

Older People ◽

Premature Mortality ◽

Public Health Issue ◽

Healthy Weight ◽

Inclusion Criteria ◽

Active Lifestyle ◽

Promising Tool ◽

Meta Analyses ◽

The Relationship

Background: Obesity is an important public health issue that has increased globally in the last decade and continues to be one of the main causes of morbidity and premature mortality. An accumulating body of evidence suggests that contact with nature is a valuable resource for the promotion of a more active lifestyle and seems to have a central role in maintaining a healthy weight. The authors conducted a systematic review to summarize the findings of studies that investigated the relationship between natural spaces and obesity. Methods: Following Primary Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a literature search was conducted using 11 databases for studies fully available in English and published between 2010 and 2020, with adults (18–64 y) and/or older people (≥65 y). Results: Fifty studies were found that met all the inclusion criteria. The majority (68%) of papers found that higher availability and less distance to green and blue spaces are associated with lower levels of adiposity. These associations were positive, even after adjusting for the demographic and socioeconomic factors. Conclusions: Exploring the characteristics of green and blue spaces seems to be a promising tool for urban planning and health policies. The authors suggest the implementation of exercise programs in contact with nature for future interventions.

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A Systematic Review on Leadership Styles in Small and Medium-Sized Enterprises

GATR Journal of Management and Marketing Review - JMMR Vol 4(3) JUL-SEP 2019 ◽

10.35609/jmmr.2021.6.3(2) ◽

2021 ◽

Vol 6 (3) ◽

pp. 158-166

Author(s):

Sharon Esther Anak Donny Sita ◽

Nor Ashikin Mohd Nor

Keyword(s):

Systematic Review ◽

Leadership Styles ◽

Leadership Style ◽

Small And Medium Enterprises ◽

Jel Classification ◽

Inclusion Criteria ◽

Paper Review ◽

Meta Analyses ◽

Medium Enterprises ◽

The Relationship

Objective - The purpose of this paper is to conduct a systematic review of the leadership style practiced by leaders in small and medium-sized enterprises. Methodology/Technique - Following the protocol guidance known as the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flowchart, a total of six articles were reviewed and analysed after meeting inclusion criteria and being deemed relevant to the goals of this paper. Findings - The results of the study suggested that the leadership styles of leaders in the context of small and medium enterprises are based on the following elements: 1) the background of an organization; 2) the characteristics of the leader; 3) the relationship between leader and followers; and 4) the position of the followers. Novelty - This paper contributes to the knowledge on leadership style in general, specifically in the context of small and medium-sized enterprises. Type of Paper - Review. Keywords: Leader; leadership style; PRISMA; small and medium-sized enterprises; systematic literature review. JEL Classification: L20, L29.

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