scholarly journals Estimation of excess all-cause mortality due to COVID-19 in Thailand

2022 ◽  
Author(s):  
Chaiwat Wilasang ◽  
Thanchanok Lincharoen ◽  
Charin Modchang ◽  
Sudarat Chadsuthi
Keyword(s):  
Correlation Coefficient ◽  
Mixed Models ◽  
New Record ◽  
Excess Mortality ◽  
Generalized Linear Mixed Models ◽  
Age Groups ◽  
Significant Rise ◽  
Excess Death ◽  
All Cause Mortality ◽  
Excess Deaths

Background: Thailand has recently experienced the most prominent COVID-19 outbreak, resulting in a new record for COVID-19 cases and deaths. To assess the influence of the COVID-19 outbreak on mortality, we aimed to estimate excess mortality in Thailand. Methods: We estimated the baseline number of deaths in the absence of COVID-19 using generalized linear mixed models (GLMMs). The models were adjusted for seasonality and demographics. We evaluated the excess mortality from April to October 2021 in Thailand. Results: We found that the estimated cumulative excess death from April to October 2021 was 14.3% (95% CI: 8.6%-18.8%) higher than the baseline. The results also showed that the excess deaths in males were higher than in females by approximately 26.3%. The excess deaths directly caused by the COVID-19 infections accounted for approximately 75.0% of the all-cause excess deaths. Furthermore, the cumulative COVID-19 cases were found to be correlated with the cumulative excess deaths with a correlation coefficient of 0.9912 (95% CI, 0.9392-0.9987). Conclusions: The recent COVID-19 outbreak in Thailand significantly impacts mortality and affects people for specific ages and sex. During the outbreak in 2021, there was a significant rise in excess fatalities, especially in the older age groups. The increase in mortality was higher in men than in women.

scholarly journals Estimation of Excess Mortality and Years of Life Lost to COVID-19 in Norway and Sweden between March and November 2020

2021 ◽  
Vol 18 (8) ◽  
pp. 3913
Author(s):  
Martin Rypdal ◽  
Kristoffer Rypdal ◽  
Ola Løvsletten ◽  
Sigrunn Holbek Sørbye ◽  
Elinor Ytterstad ◽  
...  
Keyword(s):  
Excess Mortality ◽  
Age Groups ◽  
Years Of Life Lost ◽  
Regressive Model ◽  
Epidemic Period ◽  
All Cause Mortality ◽  
Auto Regressive ◽  
Expected Mortality ◽  
Auto Regressive Model ◽  
Excess Deaths

We estimate the weekly excess all-cause mortality in Norway and Sweden, the years of life lost (YLL) attributed to COVID-19 in Sweden, and the significance of mortality displacement. We computed the expected mortality by taking into account the declining trend and the seasonality in mortality in the two countries over the past 20 years. From the excess mortality in Sweden in 2019/20, we estimated the YLL attributed to COVID-19 using the life expectancy in different age groups. We adjusted this estimate for possible displacement using an auto-regressive model for the year-to-year variations in excess mortality. We found that excess all-cause mortality over the epidemic year, July 2019 to July 2020, was 517 (95%CI = (12, 1074)) in Norway and 4329 [3331, 5325] in Sweden. There were 255 COVID-19 related deaths reported in Norway, and 5741 in Sweden, that year. During the epidemic period of 11 March–11 November, there were 6247 reported COVID-19 deaths and 5517 (4701, 6330) excess deaths in Sweden. We estimated that the number of YLL attributed to COVID-19 in Sweden was 45,850 [13,915, 80,276] without adjusting for mortality displacement and 43,073 (12,160, 85,451) after adjusting for the displacement accounted for by the auto-regressive model. In conclusion, we find good agreement between officially recorded COVID-19 related deaths and all-cause excess deaths in both countries during the first epidemic wave and no significant mortality displacement that can explain those deaths.

scholarly journals Excess deaths reveal unequal impact of COVID-19 in Ecuador

2021 ◽  
Vol 6 (9) ◽  
pp. e006446
Author(s):  
Leticia Cuéllar ◽  
Irene Torres ◽  
Ethan Romero-Severson ◽  
Riya Mahesh ◽  
Nathaniel Ortega ◽  
...  
Keyword(s):  
Diagnostic Testing ◽  
Age Groups ◽  
Indigenous Women ◽  
Indigenous Populations ◽  
Significant Finding ◽  
Age Group ◽  
Excess Death ◽  
Higher Ed ◽  
All Cause Mortality ◽  
Excess Deaths

Latin America has struggled to control the transmission of COVID-19. Comparison of excess death (ED) rates during the pandemic reveals that Ecuador is among the highest impacted countries. In this analysis, we update our previous findings with the most complete all-cause mortality records available for 2020, disaggregated by sex, age, ethnicity and geography. Our study shows that in 2020, Ecuador had a 64% ED rate (95% CI 63% to 65%) or 64% more deaths than expected. Men had a higher ED rate, 75% (95% CI 73% to 76%), than women’s 51% (95% CI 49% to 52%), and this pattern of higher EDs for men than women held for most age groups. The only exception was the 20–29 age group, where women had 19% more deaths, compared to 10% more deaths for men, but that difference is not statistically significant. The analysis provides striking evidence of the lack of COVID-19 diagnostic testing in Ecuador: the confirmed COVID-19 deaths in 2020 accounted for only 21% of total EDs. Our significant finding is that indigenous populations, who typically account for about 5% of the deaths, show almost four times the ED rate of the majority mestizo group. Indigenous women in each age group have higher ED rates than the general population and, in ages between 20 and 49 years, they have higher ED rates than indigenous men. Indigenous women in the age group 20–29 years had an ED rate of 141%, which is commensurate to the ED rate of indigenous women older than 40 years.

Excess Mortality During the COVID-19 Pandemic in Philadelphia

2021 ◽  
pp. e1-e6
Author(s):  
Megan Todd ◽  
Meagan Pharis ◽  
Sam P. Gulino ◽  
Jessica M. Robbins ◽  
Cheryl Bettigole
Keyword(s):  
Public Health ◽  
Excess Mortality ◽  
Poisson Model ◽  
People Of Color ◽  
Mortality Data ◽  
Registration System ◽  
Vital Registration System ◽  
All Cause Mortality ◽  
Race Ethnicity ◽  
Excess Deaths

Objectives. To estimate excess all-cause mortality in Philadelphia, Pennsylvania, during the COVID-19 pandemic and understand the distribution of excess mortality in the population. Methods. With a Poisson model trained on recent historical data from the Pennsylvania vital registration system, we estimated expected weekly mortality in 2020. We compared these estimates with observed mortality to estimate excess mortality. We further examined the distribution of excess mortality by age, sex, and race/ethnicity. Results. There were an estimated 3550 excess deaths between March 22, 2020, and January 2, 2021, a 32% increase above expectations. Only 77% of excess deaths (n=2725) were attributed to COVID-19 on the death certificate. Excess mortality was disproportionately high among older adults and people of color. Sex differences varied by race/ethnicity. Conclusions. Excess deaths during the pandemic were not fully explained by COVID-19 mortality; official counts significantly undercount the true death toll. Far from being a great equalizer, the COVID-19 pandemic has exacerbated preexisting disparities in mortality by race/ethnicity. Public Health Implications. Mortality data must be disaggregated by age, sex, and race/ethnicity to accurately understand disparities among groups. (Am J Public Health. Published online ahead of print June 10, 2021: e1–e6. https://doi.org/10.2105/AJPH.2021.306285 )

scholarly journals Excess mortality in Guadeloupe and Martinique, islands of the French West Indies, during the chikungunya epidemic of 2014

2018 ◽  
Vol 146 (16) ◽  
pp. 2059-2065 ◽  
Author(s):  
A. R. R. Freitas ◽  
P. M. Alarcón-Elbal ◽  
M. R. Donalisio
Keyword(s):  
Strong Correlation ◽  
Excess Mortality ◽  
Pearson Correlation ◽  
Age Groups ◽  
Epidemiological Data ◽  
Mortality Data ◽  
Surveillance Systems ◽  
Mortality And Morbidity ◽  
The Impact ◽  
Excess Deaths

AbstractIn some chikungunya epidemics, deaths are not completely captured by traditional surveillance systems, which record case and death reports. We evaluated excess deaths associated with the 2014 chikungunya virus (CHIKV) epidemic in Guadeloupe and Martinique, Antilles. Population (784 097 inhabitants) and mortality data, estimated by sex and age, were accessed from the Institut National de la Statistique et des Études Économiques in France. Epidemiological data, cases, hospitalisations and deaths on CHIKV were obtained from the official epidemiological reports of the Cellule de Institut de Veille Sanitaire in France. Excess deaths were calculated as the difference between the expected and observed deaths for all age groups for each month in 2014 and 2015, considering the upper limit of 99% confidence interval. The Pearson correlation coefficient showed a strong correlation between monthly excess deaths and reported cases of chikungunya (R= 0.81,p< 0.005) and with a 1-month lag (R= 0.87,p< 0.001); and a strong correlation was also observed between monthly rates of hospitalisation for CHIKV and excess deaths with a delay of 1 month (R= 0.87,p< 0.0005). The peak of the epidemic occurred in the month with the highest mortality, returning to normal soon after the end of the CHIKV epidemic. There were excess deaths in almost all age groups, and excess mortality rate was higher among the elderly but was similar between male and female individuals. The overall mortality estimated in the current study (639 deaths) was about four times greater than that obtained through death declarations (160 deaths). Although the aetiological diagnosis of all deaths associated with CHIKV infection is not always possible, already well-known statistical tools can contribute to the evaluation of the impact of CHIKV on mortality and morbidity in the different age groups.

scholarly journals EXCESS MORTALITY FROM COVID-19. WEEKLY EXCESS DEATH RATES BY AGE AND SEX FOR SWEDEN AND ITS MOST AFFECTED REGION

2020 ◽  
Author(s):  
Karin Modig ◽  
Anders Ahlbom ◽  
Marcus Ebeling
Keyword(s):  
Causes Of Death ◽  
Excess Mortality ◽  
National Level ◽  
Mortality Rates ◽  
Regional Level ◽  
Death Rates ◽  
Excess Death ◽  
All Cause Mortality ◽  
Specific Mortality ◽  
Age And Sex

Abstract Background Sweden has one of the highest numbers of COVID-19 deaths per inhabitant globally. However, absolute death counts can be misleading. Estimating age- and sex-specific mortality rates is necessary in order to account for the underlying population structure. Furthermore, given the difficulty of assigning causes of death, excess all-cause mortality should be estimated to assess the overall burden of the pandemic. Methods By estimating weekly age- and sex-specific death rates during 2020 and during the preceding five years, our aim is to get more accurate estimates of the excess mortality attributed to COVID-19 in Sweden, and in the most affected region Stockholm. Results Eight weeks after Sweden’s first confirmed case, the death rates at all ages above 60 were higher than for previous years. Persons above age 80 were disproportionally more affected, and men suffered greater excess mortality than women in ages up to 75 years. At older ages, the excess mortality was similar for men and women, with up to 1.5 times higher death rates for Sweden and up to 3 times higher for Stockholm. Life expectancy at age 50 declined by less than 1 year for Sweden and 1.5 years for Stockholm compared to 2019. Conclusions The excess mortality has been high in older ages during the pandemic, but it remains to be answered if this is because of age itself being a prognostic factor or a proxy for comorbidity. Only monitoring deaths at a national level may hide the effect of the pandemic on the regional level.

scholarly journals Excess mortality among the elderly in 12 European countries, February and March 2012

2012 ◽  
Vol 17 (14) ◽  
Author(s):  
A Mazick ◽  
B Gergonne ◽  
J Nielsen ◽  
F Wuillaume ◽  
M J Virtanen ◽  
...  
Keyword(s):  
Preliminary Data ◽  
Influenza A ◽  
Excess Mortality ◽  
The Elderly ◽  
European Countries ◽  
H3n2 Virus ◽  
All Cause Mortality ◽  
Cold Snap ◽  
The Impact ◽  
Excess Deaths

In February and March 2012, excess deaths among the elderly have been observed in 12 European countries that carry out weekly monitoring of all-cause mortality. These preliminary data indicate that the impact of influenza in Europe differs from the recent pandemic and post-pandemic seasons. The current excess mortality among the elderly may be related to the return of influenza A(H3N2) virus, potentially with added effects of a cold snap.

scholarly journals Excess all-cause mortality during the COVID-19 pandemic in Europe – preliminary pooled estimates from the EuroMOMO network, March to April 2020

2020 ◽  
Vol 25 (26) ◽  
Author(s):  
Lasse S Vestergaard ◽  
Jens Nielsen ◽  
Lukas Richter ◽  
Daniela Schmid ◽  
Natalia Bustos ◽  
...  
Keyword(s):  
Public Health ◽  
Excess Mortality ◽  
European Countries ◽  
Public Health Action ◽  
Federal States ◽  
All Cause Mortality ◽  
Health Action ◽  
Excess Deaths

A remarkable excess mortality has coincided with the COVID-19 pandemic in Europe. We present preliminary pooled estimates of all-cause mortality for 24 European countries/federal states participating in the European monitoring of excess mortality for public health action (EuroMOMO) network, for the period March–April 2020. Excess mortality particularly affected  ≥ 65 year olds (91% of all excess deaths), but also 45–64 (8%) and 15–44 year olds (1%). No excess mortality was observed in 0–14 year olds.

scholarly journals Excess Mortality Associated With COVID-19 by Demographic Group: Evidence From Florida and Ohio

2021 ◽  
pp. 003335492110415
Author(s):  
Troy Quast ◽  
Ross Andel
Keyword(s):  
Excess Mortality ◽  
Prediction Interval ◽  
National Level ◽  
Age Groups ◽  
Black Population ◽  
Infection Rates ◽  
Black Adults ◽  
Demographic Groups ◽  
Younger Age ◽  
Excess Deaths

Objective COVID-19 mortality varies across demographic groups at the national level, but little is known about potential differences in COVID-19 mortality across states. The objective of this study was to estimate the number of all-cause excess deaths associated with COVID-19 in Florida and Ohio overall and by sex, age, and race. Methods We calculated the number of weekly and cumulative excess deaths among adults aged ≥20 from March 15 through December 5, 2020, in Florida and Ohio as the observed number of deaths less the expected number of deaths, adjusted for population, secular trends, and seasonality. We based our estimates on death certificate data from the previous 10 years. Results The results were based on ratios of observed-to-expected deaths. The ratios were 1.17 (95% prediction interval, 1.14-1.21) in Florida and 1.15 (95% prediction interval, 1.11-1.19) in Ohio. Although the largest number of excess deaths occurred in the oldest age groups, in both states the ratios of observed-to-expected deaths were highest among adults aged 20-49 (1.21; 95% prediction interval, 1.11-1.32). The ratio of observed-to-expected deaths for the Black population was especially elevated in Florida. Conclusions Although excess deaths were largely concentrated among older cohorts, the high ratios of observed-to-expected deaths among younger age groups indicate widespread effects of COVID-19. The high levels of observed-to-expected deaths among Black adults may reflect in part disparities in infection rates, preexisting conditions, and access to care. The finding of high excess deaths among Black adults deserves further attention.

scholarly journals COVID-19 and excess mortality in the United States: A county-level analysis

PLoS Medicine ◽  
2021 ◽  
Vol 18 (5) ◽  
pp. e1003571
Author(s):  
Andrew C. Stokes ◽  
Dielle J. Lundberg ◽  
Irma T. Elo ◽  
Katherine Hempstead ◽  
Jacob Bor ◽  
...  
Keyword(s):  
United States ◽  
Formal Education ◽  
Excess Mortality ◽  
Time Lag ◽  
The United States ◽  
County Level ◽  
Level Variation ◽  
Cross Sectional ◽  
All Cause Mortality ◽  
Excess Deaths

Background Coronavirus Disease 2019 (COVID-19) excess deaths refer to increases in mortality over what would normally have been expected in the absence of the COVID-19 pandemic. Several prior studies have calculated excess deaths in the United States but were limited to the national or state level, precluding an examination of area-level variation in excess mortality and excess deaths not assigned to COVID-19. In this study, we take advantage of county-level variation in COVID-19 mortality to estimate excess deaths associated with the pandemic and examine how the extent of excess mortality not assigned to COVID-19 varies across subsets of counties defined by sociodemographic and health characteristics. Methods and findings In this ecological, cross-sectional study, we made use of provisional National Center for Health Statistics (NCHS) data on direct COVID-19 and all-cause mortality occurring in US counties from January 1 to December 31, 2020 and reported before March 12, 2021. We used data with a 10-week time lag between the final day that deaths occurred and the last day that deaths could be reported to improve the completeness of data. Our sample included 2,096 counties with 20 or more COVID-19 deaths. The total number of residents living in these counties was 319.1 million. On average, the counties were 18.7% Hispanic, 12.7% non-Hispanic Black, and 59.6% non-Hispanic White. A total of 15.9% of the population was older than 65 years. We first modeled the relationship between 2020 all-cause mortality and COVID-19 mortality across all counties and then produced fully stratified models to explore differences in this relationship among strata of sociodemographic and health factors. Overall, we found that for every 100 deaths assigned to COVID-19, 120 all-cause deaths occurred (95% CI, 116 to 124), implying that 17% (95% CI, 14% to 19%) of excess deaths were ascribed to causes of death other than COVID-19 itself. Our stratified models revealed that the percentage of excess deaths not assigned to COVID-19 was substantially higher among counties with lower median household incomes and less formal education, counties with poorer health and more diabetes, and counties in the South and West. Counties with more non-Hispanic Black residents, who were already at high risk of COVID-19 death based on direct counts, also reported higher percentages of excess deaths not assigned to COVID-19. Study limitations include the use of provisional data that may be incomplete and the lack of disaggregated data on county-level mortality by age, sex, race/ethnicity, and sociodemographic and health characteristics. Conclusions In this study, we found that direct COVID-19 death counts in the US in 2020 substantially underestimated total excess mortality attributable to COVID-19. Racial and socioeconomic inequities in COVID-19 mortality also increased when excess deaths not assigned to COVID-19 were considered. Our results highlight the importance of considering health equity in the policy response to the pandemic.

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