scholarly journals Protein Structures Related to Diseases

2014 ◽  
Vol 70 (a1) ◽  
pp. C22-C22
Author(s):  
Amit Sharma
Keyword(s):  
Cell Biology ◽  
Malaria Parasite ◽  
Protein Structures ◽  
Protein Translation ◽  
Significant Progress ◽  
Modern Biology ◽  
The Past ◽  
Inhibitor Discovery ◽  
The World ◽  
Important Parasite

Malaria continues to be a major cause of morbidity and mortality throughout the world. Our laboratory uses multi-disciplinary techniques within modern biology - including biochemistry, bioinformatics, cell biology, parasitology and protein crystallography to unravel the mechanism of action of important parasite proteins. Over the past few years, we have made significant progress in understanding various parasite motors involved in protein translation machinery. We have also explored structure-based inhibitor discovery routines against several malaria parasite targets. We will explore examples from our studies that highlight attributes of malaria proteins that can be exploited for discovering new inhibitors.

scholarly journals Western Objections to the Islamic Concept of Gender Equality: A Critical Review

Fahm-i-Islam ◽  
2020 ◽  
Vol 3 (1) ◽  
pp. 55-70
Author(s):  
Dr Aurangzeb
Keyword(s):  
Gender Equality ◽  
Critical Review ◽  
Critical Analysis ◽  
View Point ◽  
Significant Progress ◽  
The West ◽  
The Past ◽  
Viable Solution ◽  
The World ◽  
Islamic View

Over the past several years, despite the constant evolution of the legislation the problem of gender equality in the West has been steadily increasing. What is the reason why there is no significant progress in solving gender equality issues in the West yet? Several reports and researches have pointed out to this problem. On the contrary, Islam provides a viable solution to this ever increasing problem; for Islam has a comprehensive yet simple view of gender equality. But the West, instead of understanding Islamic principles objectively, raises objections without a thorough study. However, the Western principle of gender equality has completely failed. In this article a critical analysis of the western gender equality and Islamic principles has been carried out. It also highlights Islamic view point of gender equality. The study argues that the contemporary gender equality problems and issues that have engulfed the world particularly the Western countries can be mitigated by employing the Islamic principles of gender equality

scholarly journals Publication Trends on Mitophagy in the World and China: A 16-Year Bibliometric Analysis

2021 ◽  
Vol 9 ◽  
Author(s):  
Jingli Chen ◽  
Xin Li ◽  
Yifan Jia ◽  
Zhongyuan Xia ◽  
Jishi Ye
Keyword(s):  
Bibliometric Analysis ◽  
Cell Biology ◽  
Developed Countries ◽  
The United States ◽  
Research Progress ◽  
Publication Trends ◽  
Quality Of Results ◽  
The Past ◽  
The World

In the past 16 years, research on mitophagy has increasingly expanded to a wider range of subjects. Therefore, comprehensively analyzing the relevant progress and development trends on mitophagy research requires specific methods. To assess the hotspots, directions, and quality of results in this field worldwide, we used multiple tools to examine research progress and growing trends in research on the matter during the last 16 years (from 2005 to 2020). We also compared the quantity and quality of the literature records on mitophagy published by research institutions in China and other developed countries, reviewed China’s contribution, and examined the gap between China and these developed countries. According to the results of our bibliometric analysis, the United States and its research institutes published the most papers. We identified cell biology as the most commonly researched subject on mitophagy and AUTOPHAGY as the most popular journal for research on mitophagy. We also listed the most cited documents from around the world and China. With gradually increased funding, China is progressively becoming prominent in the field of mitophagy; nevertheless, the gap between her and major countries in the world must be closed.

Public Participation in E-Government

2010 ◽  
pp. 324-339
Author(s):  
Scott Baum ◽  
Arun Mahizhnan
Keyword(s):  
Public Participation ◽  
Digital Divide ◽  
International Comparisons ◽  
Significant Progress ◽  
The Past ◽  
The World ◽  
On Line

Singapore’s E-government model is considered to be among the best in the world. Over the past decade the Singapore government has constantly developed and re-developed its on-line presence. International comparisons have consistently rated Singapore as one of the most advanced E-government nations. However, despite significant progress towards full E-government maturity, some issues of full public participation remain. It is these issues which this chapter discusses. In particular, it will consider the ways in which a digital divide within the Singapore model has emerged, despite specific policies to address such a problem.

scholarly journals Reform in Canadian Universities

1994 ◽  
Vol 24 (2) ◽  
pp. 1-15
Author(s):  
J. M. Small
Keyword(s):  
Strategic Planning ◽  
Ad Hoc ◽  
Environmental Influence ◽  
Vice Presidents ◽  
Significant Progress ◽  
Canadian Universities ◽  
The Past ◽  
Sense Of Direction ◽  
Societal Needs ◽  
The World

This article reports a survey of academic vice-presidents and deans of Canadian universities which was undertaken in 1991. The focal topic was reform (defined as significant change), and perceptions of reform occurring over the past three years were derived by means of a questionnaire. Many changes were reported, giving the impression of highly responsive institutions, but these reforms were seen to be modest rather than bold in nature and reactive rather than pro-active. The major environmental influence impelling change was the level of funding. The reforms perceived to be most frequent and significant were mandate changes arising from strategic planning, responses to funding constraints, curriculum expansion, coping with increased student numbers, changes in administrative structure especially at the vice-presidency, and more democratic decision-making. Respondents were generally supportive of the goals which were perceived to lie behind the reforms but were not convinced that significant progress towards goals was actually being achieved. A comparison with reform in other parts of the world revealed that Canadian universities follow the decentralized ad hoc pattern found in federal nations, but there is reason to hope that strategic planning will produce a clearer sense of direction than has been typical elsewhere. The report concludes that the claim that universities are not responsive to changing societal needs is unwarranted, but that more significant lasting reforms are needed.

scholarly journals Mechanistic modeling confronts the complexity of molecular cell biology

2014 ◽  
Vol 25 (22) ◽  
pp. 3494-3496 ◽  
Author(s):  
Robert D. Phair
Keyword(s):  
Cell Biology ◽  
Experimental Tests ◽  
Mechanistic Modeling ◽  
Electrical Engineer ◽  
Biological Research ◽  
Modern Biology ◽  
The Past ◽  
Biology I ◽  
Molecular Cell Biology ◽  
Mind Set

Mechanistic modeling has the potential to transform how cell biologists contend with the inescapable complexity of modern biology. I am a physiologist–electrical engineer–systems biologist who has been working at the level of cell biology for the past 24 years. This perspective aims 1) to convey why we build models, 2) to enumerate the major approaches to modeling and their philosophical differences, 3) to address some recurrent concerns raised by experimentalists, and then 4) to imagine a future in which teams of experimentalists and modelers build—and subject to exhaustive experimental tests—models covering the entire spectrum from molecular cell biology to human pathophysiology. There is, in my view, no technical obstacle to this future, but it will require some plasticity in the biological research mind-set.

Stem cells of the oesophageal epithelium

2002 ◽  
Vol 115 (9) ◽  
pp. 1783-1789
Author(s):  
John P. Seery
Keyword(s):  
Stem Cells ◽  
Cell Biology ◽  
Epithelial Stem Cells ◽  
The Past ◽  
The World

Cancers arising in the oesophageal epithelium are among the most common fatal tumors in the world. Despite this, comparatively little is known about the cell biology and organization of this tissue. Recently, in vitro and in vivo techniques developed over the past 30 years for the study of the epidermis have been applied to the study of the oesophageal epithelium. This approach, combined with data from previous histochemical studies, has lead to the identification and isolation of putative oesophageal epithelial stem cells. Oesophageal epithelial stem cells demonstrate several unusual properties, and their identification may facilitate studies on oesophageal carcinogenesis.

Public Participation in E-Government

2013 ◽  
pp. 1044-1058
Author(s):  
Scott Baum ◽  
Arun Mahizhnan
Keyword(s):  
Public Participation ◽  
Digital Divide ◽  
International Comparisons ◽  
Significant Progress ◽  
The Past ◽  
The World ◽  
On Line

Singapore’s E-government model is considered to be among the best in the world. Over the past decade the Singapore government has constantly developed and re-developed its on-line presence. International comparisons have consistently rated Singapore as one of the most advanced E-government nations. However, despite significant progress towards full E-government maturity, some issues of full public participation remain. It is these issues which this chapter discusses. In particular, it will consider the ways in which a digital divide within the Singapore model has emerged, despite specific policies to address such a problem.

Government-With-You

2015 ◽  
pp. 711-725 ◽  
Author(s):  
Scott Baum ◽  
Arun Mahizhnan
Keyword(s):  
Public Participation ◽  
Digital Divide ◽  
International Comparisons ◽  
Significant Progress ◽  
The Past ◽  
Online Presence ◽  
The World

Singapore's e-government model is considered to be among the best in the world. Over the past decade, the Singapore government has constantly developed and re-invented its online presence. International comparisons have consistently rated Singapore as one of the most advanced e-government nations. However, despite significant progress towards full e-government maturity, some issues of full public participation remain. It is these issues that this chapter discusses. In particular, it considers the ways in which a digital divide within the Singapore model has emerged, despite specific policies to address such a problem.

scholarly journals Mitosis futures: the past is prologue

2011 ◽  
Vol 22 (21) ◽  
pp. 3933-3935 ◽  
Author(s):  
J. Richard McIntosh
Keyword(s):  
Future Study ◽  
Mitotic Spindle ◽  
Cell Biology ◽  
Significant Progress ◽  
The Past ◽  
Spindle Function ◽  
Made In

The mechanisms by which cells organize and segregate their chromosomes have been under close scrutiny for years, and significant progress has been made in understanding how mitosis works. Modern cell biology has identified most of the molecules that underlie mitotic spindle function, but the ways in which they are organized and controlled to make an effective and accurate cellular machine are exciting subjects for future study.

scholarly journals International Institute for Collaborative Cell Biology and Biochemistry—History and Memoirs from an International Network for Biological Sciences

2013 ◽  
Vol 12 (3) ◽  
pp. 339-344 ◽  
Author(s):  
L. C. Cameron
Keyword(s):  
Biological Sciences ◽  
Science Education ◽  
Cell Biology ◽  
Scientific Writing ◽  
International Institute ◽  
The Past ◽  
The World ◽  
American Society ◽  
Excellence In Science ◽  
First Time

I was invited to write this essay on the occasion of my selection as the recipient of the 2012 Bruce Alberts Award for Excellence in Science Education from the American Society for Cell Biology (ASCB). Receiving this award is an enormous honor. When I read the email announcement for the first time, it was more than a surprise to me, it was unbelievable. I joined ASCB in 1996, when I presented a poster and received a travel award. Since then, I have attended almost every ASCB meeting. I will try to use this essay to share with readers one of the best experiences in my life. Because this is an essay, I take the liberty of mixing some of my thoughts with data in a way that it not usual in scientific writing. I hope that this sacrifice of the format will achieve the goal of conveying what I have learned over the past 20 yr, during which time a group of colleagues and friends created a nexus of knowledge and wisdom. We have worked together to build a network capable of sharing and inspiring science all over the world.

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