Why there have been so few spectrum trades in the UK: lessons for Europe

Info ◽  
2010 ◽  
Vol 12 (1) ◽  
pp. 10-17 ◽  
Author(s):  
Rajen Akalu
Keyword(s):  
Real World ◽  
Spectrum Management ◽  
Reform Process ◽  
Ceteris Paribus ◽  
Empirical Observation ◽  
Content Type ◽  
Management Reform ◽  
Regulatory Decision ◽  
Frequency Management ◽  
The Uk

PurposeThis paper seeks to define a coherent management preference function for determining the conditions when the market can be effectively used in the management of spectrum based on abduction and volitional pragmatism.Design/methodology/approachVolitional pragmatism based on the logic of abduction is used to provide an explanation for real world empirical observation of few spectrum trades in the UK. This is generalized for application with wider context of European frequency management.FindingsThere has been a considerable regulatory effort directed toward spectrum trading in the EU. The UK experience with trading is clearly not what was expected. It was suggested that this is a result of an analytical approach based on deductive validationism subject to ceteris paribus assumptions. This approach does have merit but its application is over extended. This is due in large part institutional under specification of what constitutes the market and the nature of the transaction taking place.Research limitations/implicationsThe emphasis is in this paper is on the explanation of real world facts rather than normative prescription based on deductive validationism. Such an approach though fallible (all facts cannot be taken into account) is no less valuable in the process of regulatory decision making than deductive validationism.Practical implicationsThis paper provides a more coherent explanation of spectrum development and the spectrum management reform process.Originality/valueA set of conditions are provided for determining when the market can be used in the management of spectrum. This makes explicit the intended operation of the market as well as its limitations.

scholarly journals The rise and fall of the UK operating and financial review

2014 ◽  
Vol 27 (4) ◽  
pp. 655-685 ◽  
Author(s):  
N. Rowbottom ◽  
M.A.S. Schroeder
Keyword(s):  
Political Ideology ◽  
Political Support ◽  
Reporting Standard ◽  
Content Type ◽  
Regulatory Decision ◽  
Corporate Reporting ◽  
Business Lobbying ◽  
The Government ◽  
Using Data ◽  
The Uk

Purpose – The purpose of this paper is to analyse the controversial repeal of legislation requiring UK companies to disclose an Operating and Financial Review (OFR). After a lengthy period of consultation and the preparation of a reporting standard, legislation was passed in March 2005 requiring UK listed companies to disclose a separate statement of management commentary, an OFR. In November 2005 the Chancellor unexpectedly and controversially announced the repeal of the OFR during a speech to the largest business lobbying group in the UK. Design/methodology/approach – The analysis draws upon internal, private governmental documents prepared by the Treasury ministry to brief the Chancellor, publicly disclosed as a result of a legal challenge against the repeal decision. Findings – The paper describes how Treasury officials were motivated to seek deregulatory opportunities in order to gain political support for their head, Prime Minister-in-waiting, Gordon Brown. The analysis reveals how the repeal of the OFR was identified as an example of corporate deregulation, and how this perception proved to be misplaced following the reaction to the repeal decision which led to the government reinstating many OFR requirements in an enhanced Business Review in 2006. Originality/value – The paper draws on the conception of “3-D” power to analyse how a political ideology prevalent in the pre-financial crisis environment came to influence accounting technology with unexpected consequences. Using data rarely disclosed in the public domain, it illuminates the “black boxed” processes underlying regulatory decision making. The paper details how the Treasury were politically motivated to influence corporate reporting policy in the absence of concerted political lobbying, and why this episode of government intervention led to an unanticipated regulatory outcome.

scholarly journals Exploring 30 years of UK public services management reform – the case of health care

2017 ◽  
Vol 30 (6-7) ◽  
pp. 615-625 ◽  
Author(s):  
Ewan Ferlie
Keyword(s):  
Health Care ◽  
Public Management ◽  
Network Governance ◽  
Health Care Sector ◽  
Policy Reforms ◽  
Content Type ◽  
Management Reform ◽  
Big Picture ◽  
The Uk ◽  
Management Scholarship

Purpose The purpose of this paper is to offer a personal interpretation of the nature and impact of alternative narratives of public management reform evident in the UK since the 1980s. These reforms are examined through the prism of alternative bodies of public management scholarship. They are applied to the specific case of the health care sector as a concrete focus. Design/methodology/approach The study is a personal overview of various streams of policy reforms in the UK health care sector and associated public management scholarship. This is an interpretive essay. Findings The new of public management remains the dominant reform, narrative and highly embedded, even if dysfunctionally so. Network governance reforms have had some enduring influence. Digital era governance has so far had only weak influence. A reprofessionlisation counter narrative shows variable and oscillating influence. Originality/value The study contributes to a developing narrative-based stream in public management scholarship. It also provides a “big picture” assessment of reforming in the UK health care sector since the 1980s.

scholarly journals Understandings of tourism theory

2018 ◽  
Vol 73 (2) ◽  
pp. 156-168 ◽  
Author(s):  
Dimitrios P. Stergiou ◽  
David Airey
Keyword(s):  
Professional Practice ◽  
Real World ◽  
Empirical Data ◽  
Design Methodology ◽  
Content Type ◽  
Stakeholder Groups ◽  
Tourism Management ◽  
Major Stakeholder ◽  
Tourism Professionals ◽  
The Uk

Purpose This paper explores perceptions of tourism theory and its usefulness to the professional practice of tourism management as identified by the two major stakeholder groups – academics and tourism practitioners. Design/methodology/approach Data for this study were collected through the use of two electronically administered surveys with tourism academics teaching on undergraduate tourism programmes of study and tourism professionals, both based in the UK. Findings Findings suggest that tourism theory is important in understanding tourism itself. But at the same time it has pragmatic relevance, facilitating researchers and others to make sense of the real world and contributing to successful practice in tourism. Originality/value This is the first study to provide empirical data from both academic and practitioner perspectives into often contested debates about the nature and uses of tourism theory.

Police management reform, labor productivity, and citizens’ evaluation of police services

2018 ◽  
Vol 41 (6) ◽  
pp. 749-765 ◽  
Author(s):  
Matti Vuorensyrjä
Keyword(s):  
Labor Productivity ◽  
Reform Process ◽  
Police Management ◽  
Annual Growth Rate ◽  
Content Type ◽  
Management Reform ◽  
Police Services ◽  
Cost Disease ◽  
Reform Period ◽  
The Cost

Purpose This study tracks changes in labor productivity of the Finnish police force over a period of thorough management reforms (2009-2014). Theoretically, the study is based on the cost disease hypothesis. It was assumed that police management reforms have had no noticeable effect on labor productivity and that, therefore, the fact that both physical police facilities and frontline employees have been reduced during the reform years has been reflected on the output side: on the number of outputs, accessibility, and quality of police services. The paper aims to discuss this issue. Design/methodology/approach The study was conducted as a series of longitudinal function-specific output-input analyses (2000-2015). The project employed data from the Police Performance Management database, Police Citizen Surveys (PCSs, 1999-2016), and Police Personnel Surveys (1999-2015). Methodologically, it relied on two different compounded annual growth rate concepts, linear regressions and likelihood ratio analyses. Findings The rate of growth of labor productivity was unaffected by the management reform period. In fact, productivity may have declined during the reform process. Citizens’ evaluations of police services have slightly deteriorated over the management reform period. Research limitations/implications PCS data are based on quota sampling. The procedure contains random sampling elements but is not fully random. The earliest PCS data lack satisfactory population weights, which is why unweighted data had to be used in this study. Originality/value Longitudinal studies on police productivity and, relatedly, on the cost disease phenomenon are rare. Yet, the themata are potentially very significant for both citizens and policy makers.

Real‐world evidence to support regulatory decision making: New or expanded medical product indications

2021 ◽  
Author(s):  
Jessica M. Franklin ◽  
Kai‐Li Liaw ◽  
Solomon Iyasu ◽  
Cathy Critchlow ◽  
Nancy Dreyer
Keyword(s):  
Decision Making ◽  
Real World ◽  
Medical Product ◽  
Regulatory Decision ◽  
Real World Evidence

scholarly journals Real-World Evidence of Caplacizumab Use in the Management of Acute TTP

Blood ◽  
2020 ◽  
Author(s):  
Tina Dutt ◽  
Rebecca J Shaw ◽  
Matthew James Stubbs ◽  
Jun Yong ◽  
Benjamin Bailiff ◽  
...  
Keyword(s):  
Platelet Count ◽  
Real World ◽  
Patient Characteristics ◽  
Patient Access Scheme ◽  
Fda Approval ◽  
Immune Mediated ◽  
Real World Evidence ◽  
Life Saving ◽  
The Uk ◽  
Von Willebrand

The cornerstone of life-saving therapy in immune mediated thrombotic thrombocytopenic purpura (iTTP) has been plasma exchange (PEX) combined with immunomodulatory strategies. Caplacizumab, a novel anti-von Willebrand factor nanobody, trialled in two multicentre, randomised-placebo-controlled trials leading to EU and FDA approval, has been available in the UK through a patient-access scheme. Data was collected retrospectively from 2018-2020 for 85 patients receiving caplacizumab, including 4 children, from 22 UK hospitals. Patient characteristics and outcomes in the real-world clinical setting were compared with caplacizumab trial endpoints and historical outcomes in the pre-caplacizumab era. 84/85 patients received steroid and rituximab alongside PEX; 26% required intubation. Median time to platelet count normalisation (3 days), duration of PEX (7 days) and hospital stay (12 days) was comparable with RCT data. Median duration of PEX and time from PEX initiation to platelet count normalisation was favourable compared with historical outcomes (p<0.05). TTP recurrence occurred in 5/85 patients; all with persistent ADAMTS13 activity <5iu/dL. Of 31 adverse events in 26 patients, 17/31 (55%) were bleeding episodes and 5/31 (16%) were thrombotic events (two unrelated to caplacizumab); mortality was 6% (5/85), with no deaths attributed to caplacizumab. In 4/5 deaths caplacizumab was introduced >48 hours after PEX initiation (3-21 days). This real-world evidence represents the first and largest series of TTP patients receiving caplacizumab outside clinical trials, including paediatric patients. Representative of true clinical practice, the findings provide valuable information for clinicians treating TTP globally.

scholarly journals Estimating the burden of hyperkalaemia in the UK in high-risk patient populations

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
P McEwan ◽  
L Hoskin ◽  
K Badora ◽  
D Sugrue ◽  
G James ◽  
...  
Keyword(s):  
Clinical Practice ◽  
High Risk ◽  
Patient Outcomes ◽  
Real World ◽  
High Risk Patient ◽  
Incidence Rates ◽  
Funding Source ◽  
Eligible Population ◽  
Increased Risk ◽  
The Uk

Abstract Background Patients with chronic kidney disease (CKD), heart failure (HF), resistant hypertension (RHTN) and diabetes are at an increased risk of hyperkalaemia (HK) which can be potentially life-threatening, as a result of cardiac arrhythmias, cardiac arrest leading to sudden death. In these patients, renin-angiotensin-aldosterone system inhibitors (RAASi), are used to manage several cardiovascular and renal conditions, and are associated with an increased risk of HK. Assessing the burden of HK in real-world clinical practice may concentrate relevant care on those patients most in need, potentially improving patient outcomes and efficiency of the healthcare system. Purpose To assess the burden of HK in a real-world population of UK patients with at least one of: RHTN, Type I or II diabetes, CKD stage 3+, dialysis, HF, or in receipt of a prescription for RAASi. Methods Primary and secondary care data for this retrospective study were obtained from the UK Clinical Practice Research Datalink (CPRD) and linked Hospital Episode Statistics (HES). Eligible patients were identified using READ codes defining the relevant diagnosis, receipt of indication-specific medication, or, in the case of CKD, an estimated glomerular filtration rate (eGFR) ≤60 ml/min/1.73m2 within the study period (01 January 2008 to 30 June 2018) or in the five-year lookback period (2003–2007). The index date was defined as 01 January 2008 or first diagnosis of an eligible condition or RAASi prescription, whichever occurred latest. HK was defined as K+ ≥5.0 mmol/L; thresholds of ≥5.5 mmol/L and ≥6.0 mmol/L were explored as sensitivity analyses. Incidence rates of HK were calculated with 95% confidence intervals (CI). Results The total eligible population across all cohorts was 931,460 patients. RHTN was the most prevalent comorbidity (n=317,135; 34.0%) and dialysis the least prevalent (n=4,415; 0.5%). The majority of the eligible population were prescribed RAASi during follow-up (n=754,523; 81.0%). At a K+ threshold of ≥5.0 mmol/L, the dialysis cohort had the highest rate of HK (501.0 events per 1,000 patient-years), followed by HF (490.9), CKD (410.9), diabetes (355.0), RHTN (261.4) and the RAASi cohort (211.2) (Figure 1). This pattern was still observed at alternative threshold definitions of HK. Conclusion This large real-world study of UK patients demonstrates the burden of hyperkalaemia in high-risk patient populations from the UK. There is a need for effective prevention and treatment of HK, particularly in patients with CKD, dialysis or HF where increased incidence rates are observed which in turn will improve patient outcomes and healthcare resource usage. Figure 1. Rates of HK by condition Funding Acknowledgement Type of funding source: Private company. Main funding source(s): AstraZeneca

scholarly journals Multi-Drug Featurization and Deep Learning Improve Patient-Specific Predictions of Adverse Events

2021 ◽  
Vol 18 (5) ◽  
pp. 2600
Author(s):  
Ioannis N. Anastopoulos ◽  
Chloe K. Herczeg ◽  
Kasey N. Davis ◽  
Atray C. Dixit
Keyword(s):  
Machine Learning ◽  
Real World ◽  
Variable Number ◽  
Patient Specific ◽  
Real World Evidence ◽  
Genetic Features ◽  
The Uk ◽  
Therapeutic Compounds ◽  
Improve Patient ◽  
Reaction Profile

While the clinical approval process is able to filter out medications whose utility does not offset their adverse drug reaction profile in humans, it is not well suited to characterizing lower frequency issues and idiosyncratic multi-drug interactions that can happen in real world diverse patient populations. With a growing abundance of real-world evidence databases containing hundreds of thousands of patient records, it is now feasible to build machine learning models that incorporate individual patient information to provide personalized adverse event predictions. In this study, we build models that integrate patient specific demographic, clinical, and genetic features (when available) with drug structure to predict adverse drug reactions. We develop an extensible graph convolutional approach to be able to integrate molecular effects from the variable number of medications a typical patient may be taking. Our model outperforms standard machine learning methods at the tasks of predicting hospitalization and death in the UK Biobank dataset yielding an R2 of 0.37 and an AUC of 0.90, respectively. We believe our model has potential for evaluating new therapeutic compounds for individualized toxicities in real world diverse populations. It can also be used to prioritize medications when there are multiple options being considered for treatment.

Medical treatment and best interests: judicial interpretation of values, wishes and beliefs under the Mental Capacity Act 2005

2020 ◽  
Vol 22 (3) ◽  
pp. 165-173
Author(s):  
Owen P. O'Sullivan
Keyword(s):  
Medical Treatment ◽  
Clinical Decision ◽  
Case Law ◽  
Decision Makers ◽  
Best Interests ◽  
Content Type ◽  
The Supreme Court ◽  
Mental Capacity Act 2005 ◽  
Mental Capacity Act ◽  
The Uk

Purpose The prominence of the best interests principle in the Mental Capacity Act 2005 represented an important transition to a more resolutely patient-centred model regarding decision-making for incapable adults (“P”). This paper aims to examine the courts’ consideration of P’s values, wishes and beliefs in the context of medical treatment, reflect on whether this has resulted in a wide interpretation of the best interests standard and consider how this impacts clinical decision makers. Design/methodology/approach A particular focus will be on case law from the Court of Protection of England and Wales and the Supreme Court of the UK. Cases have been selected for discussion on the basis of the significance of their judgements for the field, the range of issues they illustrate and the extent of commentary and attention they have received in the literature. They are presented as a narrative review and are non-exhaustive. Findings With respect to values, wishes and beliefs, the best interests standard’s interpretation in the courts has been widely varied. Opposing tensions and thematic conflicts have emerged from this case law and were analysed from the perspective of the clinical decision maker. Originality/value This review illustrates the complexity and gravity of decisions of the clinical decision makers and the courts have considered in the context of best interests determinations for incapacitated adults undergoing medical treatment. Subsequent to the first such case before the Supreme Court of the UK, emerging case law trends relating to capacity legislation are considered.

Complementarity of capabilities across cultures

2019 ◽  
Vol 26 (4) ◽  
pp. 567-585 ◽  
Author(s):  
Thomas Anning-Dorson
Keyword(s):  
Cultural Context ◽  
Structural Equation ◽  
Social Institutions ◽  
Equation Modeling ◽  
Service Firms ◽  
Complementarity Effect ◽  
Content Type ◽  
Cultural Contexts ◽  
Customer Involvement ◽  
The Uk

Purpose The purpose of this paper is to investigate how service firms across two different cultural contexts use their customer involvement capabilities to create competitive advantage. The study further assesses the possible complementarity effect of innovation and involvement capabilities in enhancing firm competitiveness. Lastly, the study draws on the complementarity of capabilities and social institutions to examine whether different cultural contexts explain the use of involvement capability among service firms. Design/methodology/approach The study sampled service firms from an emerging economy (India) and high-income economy (The UK), which have different cultural contexts (collectivism/individualist) to assess the hypothesized relationship. Data collection processes were adapted to the contexts to optimize reliability and relevance. Multi-group structural equation modeling was used in analyzing the data. Findings The study finds that cultural contexts explain the positive relationship between customer involvement capability and firm competitiveness such that in collectivist cultures, involvement capability is more positively related to competitiveness but negative in individualistic contexts. However, in both contexts, service firms can through capability bundling increase firm competitiveness. The study found that the complementarity effects of innovation and involvement capabilities were found to be positive in both contexts. Originality/value This study departs from previous studies by arguing that customer involvement is a complementary capability that helps exploit the potential of innovation capability of service firms. This study further demonstrates that cultural context defines the effectiveness of involvement capability in achieving firm competitiveness.

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