scholarly journals 3D printed bio-models for medical applications

2017 ◽  
Vol 23 (2) ◽  
pp. 227-235 ◽  
Author(s):  
Yee Ling Yap ◽  
Yong Sheng Edgar Tan ◽  
Heang Kuan Joel Tan ◽  
Zhen Kai Peh ◽  
Xue Yi Low ◽  
...  

Purpose The design process of a bio-model involves multiple factors including data acquisition technique, material requirement, resolution of the printing technique, cost-effectiveness of the printing process and end-use requirements. This paper aims to compare and highlight the effects of these design factors on the printing outcome of bio-models. Design/methodology/approach Different data sources including engineering drawing, computed tomography (CT), and optical coherence tomography (OCT) were converted to a printable data format. Three different bio-models, namely, an ophthalmic model, a retina model and a distal tibia model, were printed using two different techniques, namely, PolyJet and fused deposition modelling. The process flow and 3D printed models were analysed. Findings The data acquisition and 3D printing process affect the overall printing resolution. The design process flows using different data sources were established and the bio-models were printed successfully. Research limitations/implications Data acquisition techniques contained inherent noise data and resulted in inaccuracies during data conversion. Originality/value This work showed that the data acquisition and conversion technique had a significant effect on the quality of the bio-model blueprint and subsequently the printing outcome. In addition, important design factors of bio-models were highlighted such as material requirement and the cost-effectiveness of the printing technique. This paper provides a systematic discussion for future development of an engineering design process in three-dimensional (3D) printed bio-models.

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Shiya Li ◽  
Usman Waheed ◽  
Mohanad Bahshwan ◽  
Louis Zizhao Wang ◽  
Livia Mariadaria Kalossaka ◽  
...  

Purpose A three-dimensional (3D) printed custom-fit respirator mask has been proposed as a promising solution to alleviate mask-related injuries and supply shortages during COVID-19. However, creating a custom-fit computer-aided design (CAD) model for each mask is currently a manual process and thereby not scalable for a pandemic crisis. This paper aims to develop a novel design process to reduce overall design cost and time, thus enabling the mass customisation of 3D printed respirator masks. Design/methodology/approach Four data acquisition methods were used to collect 3D facial data from five volunteers. Geometric accuracy, equipment cost and acquisition time of each method were evaluated to identify the most suitable acquisition method for a pandemic crisis. Subsequently, a novel three-step design process was developed and scripted to generate respirator mask CAD models for each volunteer. Computational time was evaluated and geometric accuracy of the masks was evaluated via one-sided Hausdorff distance. Findings Respirator masks were successfully generated from all meshes, taking <2 min/mask for meshes of 50,000∼100,000 vertices and <4 min for meshes of ∼500,000 vertices. The average geometric accuracy of the mask ranged from 0.3 mm to 1.35 mm, depending on the acquisition method. The average geometric accuracy of mesh obtained from different acquisition methods ranged from 0.56 mm to 1.35 mm. A smartphone with a depth sensor was found to be the most appropriate acquisition method. Originality/value A novel and scalable mass customisation design process was presented, which can automatically generate CAD models of custom-fit respirator masks in a few minutes from a raw 3D facial mesh. Four acquisition methods, including the use of a statistical shape model, a smartphone with a depth sensor, a light stage and a structured light scanner were compared; one method was recommended for use in a pandemic crisis considering equipment cost, acquisition time and geometric accuracy.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Kaiyang Zhu ◽  
Zichen Deng ◽  
Shi Dai ◽  
Yajun Yu

Purpose This study aims to focus on the effect of interlayer bonding and thermal decomposition on the mechanical properties of fused filament fabrication-printed polylactic acid specimens at high extrusion temperatures. Design/methodology/approach A printing process, that is simultaneous manufacturing of contour and specimen, is used to improve the printing accuracy at high extrusion temperatures. The effects of the extrusion temperature on the mechanical properties of the interlayer and intra-layer are evaluated via tensile experiments. In addition, the microstructure evolution affected by the extrusion temperature is observed using scanning electron microscopy. Findings The results show that the extrusion temperature can effectively improve the interlayer bonding property; however, the mechanical properties of the specimen for extrusion temperatures higher than 270°C may worsen owing to the thermal decomposition of the polylactic acid (PLA) material. The optimum extrusion temperature of PLA material in the three-dimensional (3D) printing process is recommended to be 250–270°C. Originality/value A temperature-compensated constitutive model for 3D printed PLA material under different extrusion temperatures is proposed. The present work facilitates the prediction of the mechanical properties of specimens at an extrusion temperature for different printing temperatures and different layers.


2016 ◽  
Vol 22 (2) ◽  
pp. 251-257 ◽  
Author(s):  
Xiaoyong Tian ◽  
Ming Yin ◽  
Dichen Li

Purpose Artificial electromagnetic (EM) medium and devices are designed with integrated micro- and macro-structures depending on the EM transmittance performance, which is difficult to fabricate by the conventional processes. Three-dimensional (3D) printing provides a new solution for the delicate artificial EM medium. This paper aims to first review the applications of 3D printing in the fabrication of EM medium briefly, mainly focusing on photonic crystals, metamaterials and gradient index (GRIN) devices. Then, a new design and fabrication strategy is proposed for the EM medium based on the 3D printing process, which was verified by the implementation of a 3D 90o Eaton lens based on GRIN metamaterials. Design/methodology/approach A new design and manufacturing strategy driven by the physical (EM transmittance) performance is proposed to illustrate the realization procedures of EM medium based device with controllable micro- and macro-structures. Stereolithography-based 3D printing process is used to obtain the designed EM device, an GRIN Eaton lens. The EM transmittance of the Eaton lens was validated experimentally and by simulation. Findings A 3D 90o Eaton lens was realized based on GRIN metamaterials structure according to the proposed design and manufacturing strategy, which had the broadband (12-18 GHz) and low loss characteristic. The feasibility of 3D printing for the artificial EM medium and GRIN devices has been verified for the further real applications in the industries. Originality/value The applications of 3D printing in artificial EM medium and devices were systematically reviewed. A new design strategy driven by physical performance for the EM device was proposed and validated by the firstly 3D printed 3D Eaton lens.


2019 ◽  
Vol 26 (2) ◽  
pp. 238-248
Author(s):  
Jiwoon Lee ◽  
Jesse Walker ◽  
Sanjay Natarajan ◽  
Sung Yi

Purpose Extrusion-based additive manufacturing (AM) has been considered as a promising technique to fabricate scaffolds for tissue engineering due to affordability, versatility and ability to print porous structures. The reliability and controllability of the printing process are necessary to produce 3D-printed scaffolds with desired properties and depend on the geometric characteristics such as porosity and pore diameter. The purpose of this study is to develop an analytical model and explore its effectiveness in the prediction of geometric characteristics of 3D-printed scaffolds. Design/methodology/approach An analytical model was developed to simulate the geometric characteristics of scaffolds produced by extrusion-based AM using fluid mechanics. Polycaprolactone (PCL) was chosen as a scaffold material and was assumed to be a non-Newtonian fluid for the model. The effectiveness of the model was verified through comparison with the experimental results. Findings A comparison study between simulation and experimental results shows that strut diameter, pore size and porosity of scaffolds can be predicted by using extrusion pressure, temperature, nozzle diameter, nozzle length and printing speed. Simulation results demonstrate that geometric characteristics have a strong relationship with processing parameters, and the model developed in this study can be used for predicting the scaffold properties for the extrusion-based 3D bioprinting process. Originality/value The present study provides a prediction model that can simulate the printing process by a simple input of processing parameters. The geometric characteristics can be predicted prior to the experimental verification, and such prediction will reduce the process time and effort when a new material or method is applied.


2016 ◽  
Vol 14 (4) ◽  
pp. 752-769 ◽  
Author(s):  
Scott Greenhalgh

Purpose Rapid prototyping and three-dimensional (3D) printing allows the direct creation of objects from 3D computer-aided design files. To identify the effects 3D printing may have on student experiences and the learning of the design process, students were asked to create a design and create a prototype of that design. Design/methodology/approach This study follows an experimental design involving four total courses of interior design students. After conceptualizing a design, students were randomly selected to either create the prototype by hand or given access to 3D printing equipment. The models were graded by three subject experts using a rubric that focused on three key aspects of the model project, namely, craftsmanship, design quality and scale (proportion). Findings All three measures produced significant mean differences with a medium effect size when comparing the 3D printed models to the traditionally built models. Additional observations provided insights into the design processes approached by students using hand-constructed and 3D printed modeling. The most notable difference was the propensity for curved and rectilinear shapes by available design technologies. Research limitations/implications The experiment showed that the design technology (3D printing) did have an impact on the designs students conceptualized. This suggests that students do connect ideation to implementation, and the availability of enabling technology impacts the design process. This research was conducted in an interior design environment and consists of primarily female students. The experimental research may be limited to design programs with similar student populations and levels of exposure to various design technologies. Practical implications This research is designed to provide instructors and programs valuable information when looking at implementing new design technologies into the curriculum. Instructors are made aware that new design technologies do impact student design strategies. Additionally, although certain design technologies allow for revisions, it was apparent that students continued to be resistant to revise their initial models suggesting instructors prepare to address this issue in instruction. Social implications There is a strong body of research indicating inequality in education where students have differing access to technologies in schools. This research shows that 3D printing, similar to many technologies in education, can impact the cognitive processes of content being learned. Originality/value There is limited research on how design technologies impact design cognition and the experiences of design students. This paper looked specifically at one design technology (3D printing/rapid prototyping) and how it impacts the processes and quality of design, in addition to the quality of design products (prototypes or models). Research such as this provides instructors and faculty members an insight into how design technologies impact their curriculum.


2020 ◽  
Vol 33 (4/5) ◽  
pp. 323-331
Author(s):  
Mohsen pakdaman ◽  
Raheleh akbari ◽  
Hamid reza Dehghan ◽  
Asra Asgharzadeh ◽  
Mahdieh Namayandeh

PurposeFor years, traditional techniques have been used for diabetes treatment. There are two major types of insulin: insulin analogs and regular insulin. Insulin analogs are similar to regular insulin and lead to changes in pharmacokinetic and pharmacodynamic properties. The purpose of the present research was to determine the cost-effectiveness of insulin analogs versus regular insulin for diabetes control in Yazd Diabetes Center in 2017.Design/methodology/approachIn this descriptive–analytical research, the cost-effectiveness index was used to compare insulin analogs and regular insulin (pen/vial) for treatment of diabetes. Data were analyzed in the TreeAge Software and a decision tree was constructed. A 10% discount rate was used for ICER sensitivity analysis. Cost-effectiveness was examined from a provider's perspective.FindingsQALY was calculated to be 0.2 for diabetic patients using insulin analogs and 0.05 for those using regular insulin. The average cost was $3.228 for analog users and $1.826 for regular insulin users. An ICER of $0.093506/QALY was obtained. The present findings suggest that insulin analogs are more cost-effective than regular insulin.Originality/valueThis study was conducted using a cost-effectiveness analysis to evaluate insulin analogs versus regular insulin in controlling diabetes. The results of study are helpful to the government to allocate more resources to apply the cost-effective method of the treatment and to protect patients with diabetes from the high cost of treatment.


2016 ◽  
Vol 20 (2) ◽  
pp. 76-85 ◽  
Author(s):  
Cathy Treadaway ◽  
Gail Kenning

Purpose – The purpose of this paper is to present design research investigating the development of sensory textiles with embedded electronics to support the wellbeing of people with late stage dementia in residential care. Design/methodology/approach – The research presented is qualitative and uses a mixed method approach informed by grounded practical theory and positive design methodologies. It uses an inclusive and participatory co-design process involving people with dementia and their families with an interdisciplinary team of experts. Findings – Both the co-design process and the artefacts developed have been beneficial in supporting wellbeing. The textile artefacts have been found to soothe, distract and comfort people with dementia. They have also been shown to facilitate in the moment conversational bridges between family members and carers with persons with dementia. Research limitations/implications – The findings are based on a small cohort of participants, observational reports and descriptive accounts from family members and carers. Practical implications – The paper proposes ways in which simple hand-crafted textiles can be used beneficially to support the wellbeing of people with late stage dementia. It provides examples of how technology can be used to personalise and extend the sensory properties of the artefacts created. Social implications – It promotes an inclusive co-design methodology involving care professionals, carers and people with dementia with designers and technologists. Originality/value – The paper describes new ways of extending sensory properties of textiles through the integration of technology.


2018 ◽  
Vol 16 (1) ◽  
pp. 25-43 ◽  
Author(s):  
Ayman Ahmed Ezzat Othman ◽  
Nermeen Mohamed Amin Abdelwahab

Purpose The purpose of this paper is to develop a framework integrating risk management (RM) into the architectural design process (ADP) as an approach for delivering sustainable construction projects. Design/methodology/approach A research methodology, which consisted of literature review and field study, is designed to accomplish four objectives. First, to provide a comprehensive literature review of the concepts of sustainability, ADP and RM. Second, to present and synthesis the results of two relevant studies focused on identifying, quantifying and classifying the risks associated with ADP; and investigating the perception and application of Egyptian architectural design firms (ADFs) towards integrating RM into ADP as an approach for delivering sustainable construction projects. Third, to develop a framework that integrates RM into ADP towards delivering sustainable construction projects. Finally, to draw conclusions and recommendations to improve the practice of delivering sustainable construction projects among ADFs, construction professionals and governmental authorities. Findings ADP is a fundamental phase of the construction process because the decisions adopted during this phase affect the project performance throughout its life cycle. While RM is widely applied in different sectors of the construction industry, its application in ADP received scant attention in construction literature. The research identified 18 key risks that affect the sustainable delivery of construction projects during ADP. The architect, the client and the project manager are the highest ranked responsible parties for the occurrence of these key risks. The field study highlighted the need to develop a framework to facilitate integrating RM into ADP. Research limitations/implications This paper focused only on the integration of RM into ADP. Originality/value The conducted literature review and field study provided an in-depth understanding of the key risks that affect the sustainable delivery of construction projects during ADP. Through its five stages, the proposed framework is expected to serve as a foundation for integrating RM into ADP as an approach for delivering sustainable projects. This ideology has received scant attention in construction literature. The developed framework represents a synthesis that is novel and creative in thought and adds value to the knowledge in a manner that has not previously occurred.


2017 ◽  
Vol 23 (6) ◽  
pp. 1196-1215 ◽  
Author(s):  
Maria Isabel Rodriguez Ferradas ◽  
José A. Alfaro Tanco ◽  
Francesco Sandulli

Purpose The purpose of this paper is to explore the relevant factors that influence the implementation of innovation contests, an open innovation (OI) practice that has been extensively reported in the literature as a managerial tool for external knowledge search. The authors focus the study on the context of small and medium enterprises (SMEs). Design/methodology/approach The approach is a retrospective case study. This methodology allows an in-depth view into a Spanish SME that successfully undertook two new product development processes thanks to the deployment of innovation contests. Findings The main context factors influencing innovation contests as managerial tool are ambidexterity, technological and marketing turbulence and intermediaries, among others. Regarding design factors, this work highlights the role of attraction and facilitation. Additionally, the repetitive implementation of innovation contests creates a corporate culture that promotes OI activities. Practical implications Managers will understand that they can use innovation contests as a managerial tool, and knowing the factors that need to be taken into account when implementing an innovation contest will help SMEs managers to make better use of this practice. Originality/value This case study enriches the literature of both innovation contests and topics relevant to SMEs. Based on a theoretical framework of the design factors that influence the implementation of innovation contests, the authors propose a research framework that incorporates those context factors in association with an SME.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Shahryar Habibi

Purpose The purpose of this study is to design a zero-energy home, which is known to be capable of balancing its own energy production and consumption close to zero. Development of low-energy homes and zero-net energy houses (ZEHs) is vital to move toward energy efficiency and sustainability in the built environment. To achieve zero or low energy targets in homes, it is essential to use the design process that minimizes the need for active mechanical systems. Design/methodology/approach The methodology discussed in this paper consists of an interfacing building information modeling (BIM) tool and a simulation software to determine the potential influence of phase change materials on designing zero-net energy homes. Findings BIM plays a key role in advancing methods for architects and designers to communicate through a common software platform, analyze energy performance through all stages of the design and construction process and make decisions for improving energy efficiency in the built environment. Originality/value This paper reviews the literature relevant to the role of BIM in helping energy simulation for the performance of residential homes to more advanced levels and in modeling the integrated design process of ZEHs.


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