The rigorous evaluation of Enterprise Java Bean technology

In national codes of ethics the practice of psychology is presented as rooted in scientific knowledge, professional skills, and experience. However, it is not self-evident that the body of scientific knowledge in psychology provides an adequate basis for current professional practice. Professional training and experience are seen as necessary for the application of psychological knowledge, but they appear insufficient to defend the soundness of one's practices when challenged in judicial proceedings of a kind that may be faced by psychologists in the European Union in the not too distant future. In seeking to define the basis for the professional competence of psychologists, this article recommends taking a position of modesty concerning the scope and effectiveness of psychological interventions. In many circumstances, psychologists can only provide partial advice, narrowing down the range of possible courses of action more by eliminating unpromising ones than by pointing out the most correct or most favorable one. By emphasizing rigorous evaluation, the profession should gain in accountability and, in the long term, in respectability.

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CD276 is an important player in macrophage recruitment into the tumor and an upstream regulator for PAI-1

Scientific Reports ◽

10.1038/s41598-021-94360-9 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Sibel Durlanik ◽

Katrin Fundel-Clemens ◽

Coralie Viollet ◽

Heinrich J. Huber ◽

Martin Lenter ◽

...

Keyword(s):

Clinical Prognosis ◽

Rigorous Evaluation ◽

Macrophage Recruitment ◽

Upstream Regulator ◽

Lack Of Information ◽

Important Player ◽

Inhibitory Signaling ◽

Support Tumor Growth ◽

Poor Clinical Prognosis ◽

Pai 1

AbstractMore than 70% of colorectal, prostate, ovarian, pancreatic and breast cancer specimens show expression of CD276 (B7–H3), a potential immune checkpoint family member. Several studies have shown that high CD276 expression in cancer cells correlates with a poor clinical prognosis. This has been associated with the presence of lower tumor infiltrating leukocytes. Among those, tumor-associated macrophages can comprise up to 50% of the tumor mass and are thought to support tumor growth through various mechanisms. However, a lack of information on CD276 function and interaction partner(s) impedes rigorous evaluation of CD276 as a therapeutic target in oncology. Therefore, we aimed to understand the relevance of CD276 in tumor-macrophage interaction by employing a 3D spheroid coculture system with human cells. Our data show a role for tumor-expressed CD276 on the macrophage recruitment into the tumor spheroid, and also in regulation of the extracellular matrix modulator PAI-1. Furthermore, our experiments focusing on macrophage-expressed CD276 suggest that the antibody-dependent CD276 engagement triggers predominantly inhibitory signaling networks in human macrophages.

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Factors influencing the occurrence of negative interactions between people and crocodilians in Mexico

Oryx ◽

10.1017/s0030605319000668 ◽

2021 ◽

pp. 1-9

Author(s):

Giovany Arturo González-Desales ◽

Luis Sigler ◽

Jesús García-Grajales ◽

Pierre Charruau ◽

Martha Mariela Zarco-González ◽

...

Keyword(s):

Anthropogenic Activities ◽

Biosphere Reserve ◽

Rigorous Evaluation ◽

Caiman Crocodilus ◽

Crocodylus Acutus ◽

American Crocodile ◽

Nesting Sites ◽

The Relationship ◽

Nesting Season ◽

Negative Interactions

Abstract Negative interactions between people and crocodilians have increased worldwide, but in Mexico there have been few systematic reports and no rigorous evaluation of this problem. We compiled information on negative interactions between people and the spectacled caiman Caiman crocodilus and American crocodile Crocodylus acutus from the Worldwide Crocodilian Attack Database for 1993–2018, and we investigated interactions in greater depth, through interviews with people in La Encrucijada Biosphere Reserve. We examined the relationship between the occurrence of negative interactions between people and C. acutus and the species' nesting season and abundance, and presence records. In Mexico, the frequency of negative interactions increases when anthropogenic activities occur close to nesting sites (< 30 km) and during the nesting season (February–September). In La Encrucijada, following negative interactions with crocodiles, the local inhabitants killed 30 crocodiles measuring > 2.5 m long in 2011–2012. The frequency of negative human–crocodilian interactions was not correlated with the abundance of crocodilians but was correlated with the number of presence records of crocodiles. Strategies to minimize these interactions include warnings at nesting sites, increased monitoring of anthropogenic activities during the nesting season, and management of nests to prevent them being destroyed by people.

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Towards a Functional Performance Validation Standard for Industrial Low-Back Exoskeletons: State of the Art Review

Sensors ◽

10.3390/s21030808 ◽

2021 ◽

Vol 21 (3) ◽

pp. 808

Author(s):

Mattia Pesenti ◽

Alberto Antonietti ◽

Marta Gandolla ◽

Alessandra Pedrocchi

Keyword(s):

Functional Performance ◽

State Of The Art ◽

Productivity Loss ◽

Evaluation Criteria ◽

The State ◽

Low Back ◽

Industrial Workers ◽

Rigorous Evaluation ◽

Work Related ◽

Absence From Work

While the research interest for exoskeletons has been rising in the last decades, missing standards for their rigorous evaluation are potentially limiting their adoption in the industrial field. In this context, exoskeletons for worker support have the aim to reduce the physical effort required by humans, with dramatic social and economic impact. Indeed, exoskeletons can reduce the occurrence and the entity of work-related musculoskeletal disorders that often cause absence from work, resulting in an eventual productivity loss. This very urgent and multifaceted issue is starting to be acknowledged by researchers. This article provides a systematic review of the state of the art for functional performance evaluation of low-back exoskeletons for industrial workers. We report the state-of-the-art evaluation criteria and metrics used for such a purpose, highlighting the lack of a standard for this practice. Very few studies carried out a rigorous evaluation of the assistance provided by the device. To address also this topic, the article ends with a proposed framework for the functional validation of low-back exoskeletons for the industry, with the aim to pave the way for the definition of rigorous industrial standards.

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Evaluation of Education for Public Health: A Practical Foundation for Solidarity

European Journal of Public Health ◽

10.1093/eurpub/ckz185.063 ◽

2019 ◽

Vol 29 (Supplement_4) ◽

Author(s):

M Perkiö ◽

R Harrison ◽

M Grivna ◽

D Tao ◽

C Evashwich

Keyword(s):

Public Health ◽

Health Education ◽

Health Workforce ◽

Health Professionals ◽

Public Health Education ◽

Public Health Workforce ◽

Rigorous Evaluation ◽

The Public ◽

Public Health Professionals

Abstract Education is a key to creating solidary among the professionals who advance public health’s interdisciplinary mission. Our assumption is that if all those who work in public health shared core knowledge and the skills for interdisciplinary interaction, collaboration across disciplines, venues, and countries would be facilitated. Evaluation of education is an essential element of pedagogy to ensure quality and consistency across boundaries, as articulated by the UNESCO education standards. Our study examined the evaluation studies done by programs that educate public health professionals. We searched the peer reviewed literature published in English between 2000-2017 pertaining to the education of the public health workforce at a degree-granting level. The 2442 articles found covered ten health professions disciplines and had lead authors representing all continents. Only 86 articles focused on evaluation. The majority of the papers examined either a single course, a discipline-specific curriculum or a teaching method. No consistent methodologies could be discerned. Methods ranged from sophisticated regression analyses and trends tracked over time to descriptions of focus groups and interviews of small samples. We found that evaluations were primarily discipline-specific, lacked rigorous methodology in many instances, and that relatively few examined competencies or career expectations. The public health workforce enjoys a diversity of disciplines but must be able to come together to share diverse knowledge and skills. Evaluation is critical to achieving a workforce that is well trained in the competencies pertinent to collaboration. This study informs the pedagogical challenges that must be confronted going forward, starting with a commitment to shared core competencies and to consistent and rigorous evaluation of the education related to training public health professionals. Key messages Rigorous evaluation is not sufficiently used to enhance the quality of public health education. More frequent use of rigorous evaluation in public health education would enhance the quality of public health workforce, and enable cross-disciplinary and international collaboration for solidarity.

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Experimental Investigations on Ultimate Behavior of Fabricated Mobile Scaffolds

Metals ◽

10.3390/met11060851 ◽

2021 ◽

Vol 11 (6) ◽

pp. 851

Author(s):

Heesoo Kim ◽

Jeonghyeon Lim ◽

Jeonghwa Lee ◽

Young Jong Kang ◽

Seungjun Kim

Keyword(s):

Evaluation Methods ◽

System Level ◽

Structural Safety ◽

Structural Performance ◽

Experimental Investigations ◽

Rigorous Evaluation ◽

Effective Evaluation ◽

Test Models ◽

Behavior Characteristics ◽

Structural Behaviors

A fabricated mobile scaffold has various components, including vertical members, horizontal members, braces, work plates, and castor wheels. In Korea, the structural performance of each member must be validated based on member-level structural safety criteria; this means that rigorous evaluation methods are required to secure the system-level structural safety of the fabricated mobile scaffold. To suggest rational system-level structural safety criteria and effective evaluation methods, the characteristics of the structural behaviors of the assembled structure must be investigated first. Unlike other temporary equipment, it is a product that requires convenience of use and ease of movement. Therefore, to secure the safety and usability of the structure, it is necessary to evaluate the ultimate behavior of a mobile scaffold fabricated with various material and structural types. In an experimental study, the ultimate mode and load-bearing capacity were investigated, and the appropriateness of the required performance of the mobile scaffold was reviewed. Three types of experimental test models with different materials (steel and aluminum) and stories (single-story and three-story erection) were selected and examined for vertical loads. Based on the experimental results, the ultimate behavior characteristics of the fabricated mobile scaffold were analyzed, and the ultimate load was identified.

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