Development of Micro Perfusion Cell Culture Device to Create In Vivo-Like Environments for Long-Period and Real-Time Monitoring of Cells Activities

Author(s):  
Hiroshi Kimura ◽  
Hitomi Sakai ◽  
Takatoki Yamamoto ◽  
Yasuyuki Sakai ◽  
Teruo Fujii
Head & Neck ◽  
2013 ◽  
Vol 36 (8) ◽  
pp. 1207-1215 ◽  
Author(s):  
Mazen A. Juratli ◽  
Mustafa Sarimollaoglu ◽  
Eric R. Siegel ◽  
Dmitry A. Nedosekin ◽  
Ekaterina I. Galanzha ◽  
...  

2021 ◽  
Vol 900 ◽  
pp. 115674
Author(s):  
Muthaiah Annalakshmi ◽  
Sakthivel Kumaravel ◽  
T.S.T. Balamurugan ◽  
Shen-Ming Chen ◽  
Ju-Liang He

2015 ◽  
Vol 51 (32) ◽  
pp. 6948-6951 ◽  
Author(s):  
Yanfeng Zhang ◽  
Qian Yin ◽  
Jonathan Yen ◽  
Joanne Li ◽  
Hanze Ying ◽  
...  

Anin vitroandin vivodrug-reporting system is developed for real-time monitoring of drug release via the analysis of the concurrently released near-infrared fluorescence dye.


2019 ◽  
Author(s):  
Sebastiano Bariselli ◽  
Nanami Miyazaki ◽  
Alexxai Kravitz

AbstractStimulants are one of the most widely prescribed classes of pharmaceuticals, but it is unclear which brain pathways underlie their therapeutic and adverse actions. Here, with real-time monitoring of circuit plasticity, we demonstrate that psychostimulants strengthen orbitofrontal (OFC) to dorsomedial striatum (DMS) pathway synapses, and increase striatal output in awake mice. In vivo high-frequency stimulation of OFC-DMS pathway blocked stimulant-induced potentiation and the expression of locomotor sensitization, thereby directly linking OFC-DMS plasticity to hyperactivity.


2016 ◽  
Vol 214 (6) ◽  
pp. 649-652 ◽  
Author(s):  
Hema V. Pingali ◽  
Angela K. Hilliker

Translation is carefully regulated to control protein levels and allow quick responses to changes in the environment. Certain questions about translation in vivo have been unattainable until now. In this issue, Pichon et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201605024) describe a new technique to allow real-time monitoring of translation on single mRNAs.


Nanoscale ◽  
2020 ◽  
Vol 12 (18) ◽  
pp. 10216-10225 ◽  
Author(s):  
Hongjun Zhuang ◽  
Benhao Li ◽  
Mengyao Zhao ◽  
Peng Wei ◽  
Wei Yuan ◽  
...  

Cyanine dye-coordinated upconversion nanoparticles were developed for real-time monitoring drug-induced hepatotoxicity in vivo by ratio-fluorescence and photoacoustic imaging of peroxynitrite.


2019 ◽  
Vol 43 (47) ◽  
pp. 18673-18684 ◽  
Author(s):  
Dan Zhang ◽  
Le Li ◽  
Xiaohui Ji ◽  
Yanhong Gao

Smart GSH-responsive camptothecin delivery systems for treatment of tumors and real-time monitoring in vivo and in vitro were described.


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