Prevalence of renally inappropriate medicines in older people with renal impairment — A cross‐sectional register‐based study in a large primary care population

This study investigated associations between inflammatory markers, sickness behaviour, health anxiety and self-rated health in 311 consecutive primary care patients. Poor self-rated health was associated with high sickness behaviour ( ρ = 0.28, P < 0.001; ρ = 0.42, P = 0.003) and high health anxiety ( ρ = 0.31, P < 0.001; ρ = –0.32, P = 0.003). High levels of interleukin 6 were associated with poor self-rated health in men ( ρ = 0.26, P = 0.009). Low levels of interleukin-6 were associated with poor self-rated health in women ( ρ = –0.15, P = 0.04), but this association was non-significant when adjusted for health anxiety ( ρ = –0.08, P = 0.31). These results are consistent with the theory that interoceptive processes draw on both inflammatory mediators and the state of sickness behaviour in inferring health state.

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Awareness of and attitudes towards infertility and its treatment: a cross-sectional survey of men in a United States primary care population

Asian Journal of Andrology ◽

10.4103/1008-682x.132782 ◽

2014 ◽

Vol 16 (6) ◽

pp. 858 ◽

Cited By ~ 6

Author(s):

Wayland Hsiao ◽

ChadWM Ritenour ◽

Dipak Vashi ◽

RobertS Gerhard ◽

Michael Goodman

Keyword(s):

United States ◽

Primary Care ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Primary Care Population

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The Association between Serum Magnesium Levels and Depression in an Adult Primary Care Population

Nutrients ◽

10.3390/nu11071475 ◽

2019 ◽

Vol 11 (7) ◽

pp. 1475 ◽

Cited By ~ 3

Author(s):

Emily K. Tarleton ◽

Amanda G. Kennedy ◽

Gail L. Rose ◽

Abigail Crocker ◽

Benjamin Littenberg

Keyword(s):

Primary Care ◽

Depressive Symptoms ◽

Serum Magnesium ◽

Magnesium Supplementation ◽

Cross Sectional ◽

Primary Care Population ◽

Patient Health ◽

Sectional Analysis ◽

The Relationship ◽

Univariate Analyses

Depression is common, places a large burden on the patient, their family and community, and is often difficult to treat. Magnesium supplementation is associated with improved depressive symptoms, but because the mechanism is unknown, it is unclear whether serum magnesium levels act as a biological predictor of the treatment outcome. Therefore, we sought to describe the relationship between serum magnesium and the Patient Health Questionnaire (PHQ, a measure of depression) scores. A cross-sectional analysis of medical records from 3604 adults (mean age 62 years; 42% men) seen in primary care clinics between 2015 and 2018, with at least one completed PHQ were included. The relationship between serum magnesium and depression using univariate analyses showed a significant effect when measured by the PHQ-2 (−0.19 points/mg/dL; 95% CI −0.31, −0.07; P = 0.001) and the PHQ-9 (−0.93 points/mg/dL; 95% CI −1.81, −0.06; P = 0.037). This relationship was strengthened after adjusting for covariates (age, gender, race, time between serum magnesium and PHQ tests, and presence of diabetes and chronic kidney disease) (PHQ-2: −0.25 points/mg/dL; 95% CI −3.33, −0.09; P < 0.001 and PHQ-9: −1.09 95% CI −1.96 −0.21; P = 0.015). For adults seen in primary care, lower serum magnesium levels are associated with depressive symptoms, supporting the use of supplemental magnesium as therapy. Serum magnesium may help identify the biological mechanism of depressive symptoms and identify patients likely to respond to magnesium supplementation.

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Development and validation of a short form of the Geriatric Anxiety Inventory – the GAI-SF

International Psychogeriatrics ◽

10.1017/s1041610210001237 ◽

2010 ◽

Vol 23 (1) ◽

pp. 125-131 ◽

Cited By ~ 87

Author(s):

Gerard J. Byrne ◽

Nancy A. Pachana

Keyword(s):

Primary Care ◽

Older People ◽

Short Form ◽

Community Sample ◽

Anxiety Symptoms ◽

Self Report ◽

Cross Sectional ◽

Medical Settings ◽

Epidemiological Surveys ◽

Dsm Iv

ABSTRACTBackground: Anxiety symptoms and anxiety disorders are highly prevalent among older people and are associated with considerable disability burden. While several instruments now exist to measure anxiety in older people, there is a need for a very brief self-report scale to measure anxiety symptoms in epidemiological surveys, in primary care and in acute geriatric medical settings. Accordingly, we undertook the development of such a scale, based on the Geriatric Anxiety Inventory.Methods: This is a cross-sectional study of randomly selected, community-residing, older women (N = 284; mean age 72.2 years) using receiver operating characteristic (ROC) analyses. DSM-IV diagnostic interviews were undertaken using the Mini International Diagnostic Interview, fifth edition (MINI-V).Results: We developed a 5-item version of the Geriatric Anxiety Inventory, which we have termed the Geriatric Anxiety Inventory – Short Form (GAI-SF). We found that a score of three or greater was optimal for the detection of DSM-IV Generalized Anxiety Disorder (GAD) in this community sample. At this cut-point, sensitivity was 75%, specificity was 87%, and 86% of participants were correctly classified. GAI-SF score was not related to age, MMSE score, level of education or perceived income adequacy. Internal consistency was high (Cronbach's α = 0.81) and concurrent validity against the State-Trait Anxiety Inventory was good (rs = 0.48, p < 0.001).Conclusions: The GAI-SF is a short form of the Geriatric Anxiety Inventory, which we recommend for use in epidemiological studies. It may also be useful in primary care and acute geriatric medical settings.

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Older people's knowledge of the purpose of drugs prescribed at primary care appointments

10.22541/au.161955052.23929288/v1 ◽

2021 ◽

Author(s):

Romana Santos Gama ◽

Luiz Carlos Passos ◽

Welma Wildes Amorim ◽

Renato Morais Souza ◽

Hévila Maciel Queiroga ◽

...

Keyword(s):

Primary Care ◽

Cognitive Impairment ◽

Older People ◽

Patient Adherence ◽

Cross Sectional Study ◽

High Rate ◽

Cross Sectional ◽

Adherence To Medication ◽

Level Of Knowledge ◽

Family Practice Physician

Rationale, aims and objectives: Patient adherence to medication is related to successful pharmacotherapy; however, many patients do not take their medications as prescribed because of poor understanding of their purpose.This study aimed to assess older people’s knowledge of the purpose of drugs prescribed at medical appointments in primary care units and the possible factors related to their level of knowledge about their medications. Method: This was a cross-sectional study conducted in 22 basic health units in Brazil. Older people from this sample who were treated in a primary care setting were interviewed after a consultation with a family practice physician. Data were collected from September 2016 to March 2019. Patients aged ≥ 60 years who visited the primary care units were included in the study (n = 674). Knowledge of prescribed medications was assessed by comparing the responses to the questionnaire and the medication and prescription information. Multivariate analyses were conducted using a Poisson regression with robust variance. Results: The mean age of the sample was 70.1 (standard deviation: ± 7.1) years. Among 674 patients, 272 (40.4%) did not know the indication of at least one of their prescribed drugs; among them 78 (11.6%) did not know the indication of any of their prescribed drugs. In the final multivariate analysis, polypharmacy, illiteracy, and cognitive impairment were found to be associated with misunderstanding the purpose of at least one prescribed drug. Moreover, illiteracy and cognitive impairment were associated with a greater misunderstanding of the purpose of all prescribed drugs. Conclusions: In the studied sample, patients demonstrated a high rate of misunderstanding of the purpose of prescribed drugs. Therefore, it is necessary for health services and professionals to implement strategies that increase the quality of the guidance and instructions given to older people in order to promote adherence to treatment.

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