Poverty as an independent risk factor for in-hospital mortality in community-acquired pneumonia: A study in a developing country population

2018 ◽  
Vol 72 (5) ◽  
pp. e13085 ◽  
Author(s):  
Hassan Jahanihashemi ◽  
Mona Babaie ◽  
Soroush Bijani ◽  
Maryam Bazzazan ◽  
Behzad Bijani
Keyword(s):  
Risk Factor ◽  
Hospital Mortality ◽  
Developing Country ◽  
Independent Risk Factor ◽  
Community Acquired Pneumonia

scholarly journals Elevation of blood glucose level predicts worse outcomes in hospitalized patients with COVID-19: a retrospective cohort study

2020 ◽  
Vol 8 (1) ◽  
pp. e001476 ◽  
Author(s):  
Jianfeng Wu ◽  
Jianqiang Huang ◽  
Guochao Zhu ◽  
Qiongya Wang ◽  
Qingquan Lv ◽  
...  
Keyword(s):  
Sensitivity Analysis ◽  
Risk Factor ◽  
Blood Glucose ◽  
Hospital Mortality ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Independent Risk Factor ◽  
Cox Regression ◽  
Hospitalized Patients ◽  
Medical Resources

IntroductionWith intense deficiency of medical resources during COVID-19 pandemic, risk stratification is of strategic importance. Blood glucose level is an important risk factor for the prognosis of infection and critically ill patients. We aimed to investigate the prognostic value of blood glucose level in patients with COVID-19.Research design and methodsWe collected clinical and survival information of 2041 consecutive hospitalized patients with COVID-19 from two medical centers in Wuhan. Patients without available blood glucose level were excluded. We performed multivariable Cox regression to calculate HRs of blood glucose-associated indexes for the risk of progression to critical cases/mortality among non-critical cases, as well as in-hospital mortality in critical cases. Sensitivity analysis were conducted in patient without diabetes.ResultsElevation of admission blood glucose level was an independent risk factor for progression to critical cases/death among non-critical cases (HR=1.30, 95% CI 1.03 to 1.63, p=0.026). Elevation of initial blood glucose level of critical diagnosis was an independent risk factor for in-hospital mortality in critical cases (HR=1.84, 95% CI 1.14 to 2.98, p=0.013). Higher median glucose level during hospital stay or after critical diagnosis (≥6.1 mmol/L) was independently associated with increased risks of progression to critical cases/death among non-critical cases, as well as in-hospital mortality in critical cases. Above results were consistent in the sensitivity analysis in patients without diabetes.ConclusionsElevation of blood glucose level predicted worse outcomes in hospitalized patients with COVID-19. Our findings may provide a simple and practical way to risk stratify COVID-19 inpatients for hierarchical management, particularly where medical resources are in severe shortage during the pandemic.

scholarly journals Is community-acquired pneumonia an independent risk factor for cardiovascular disease?

2011 ◽  
Vol 39 (1) ◽  
pp. 187-196 ◽  
Author(s):  
A. Singanayagam ◽  
A. Singanayagam ◽  
D. H. J. Elder ◽  
J. D. Chalmers
Keyword(s):  
Cardiovascular Disease ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Community Acquired Pneumonia

scholarly journals QT Dispersion. Is it an Independent Risk Factor for In-hospital Mortality in Patients with Intracerebral Hemorrhage?

1999 ◽  
Vol 40 (4) ◽  
pp. 405-411 ◽  
Author(s):  
Zehra GÖLBASI ◽  
Yusuf SELÇOKI ◽  
Turali ERASLAN ◽  
Deniz KAYA ◽  
Sinan AYDOGDU
Keyword(s):  
Risk Factor ◽  
Intracerebral Hemorrhage ◽  
Hospital Mortality ◽  
Independent Risk Factor ◽  
Qt Dispersion

scholarly journals Effect of acute alcohol intoxication on mortality, coagulation, and fibrinolysis in trauma patients

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248810
Author(s):  
Il-Jae Wang ◽  
Byung-Kwan Bae ◽  
Young Mo Cho ◽  
Suck Ju Cho ◽  
Seok-Ran Yeom ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Risk Factor ◽  
Hospital Mortality ◽  
Logistic Regression Analysis ◽  
Independent Risk Factor ◽  
Alcohol Intoxication ◽  
Trauma Patients ◽  
Blood Alcohol ◽  
Fibrinolysis Shutdown

Background The effect of alcohol on the outcome and fibrinolysis phenotype in trauma patients remains unclear. Hence, we performed this study to determine whether alcohol is a risk factor for mortality and fibrinolysis shutdown in trauma patients. Materials and methods A total of 686 patients who presented to our trauma center and underwent rotational thromboelastometry were included in the study. The primary outcome was in-hospital mortality. Logistic regression analysis was performed to determine whether alcohol was an independent risk factor for in-hospital mortality and fibrinolysis shutdown. Results The rate of in-hospital mortality was 13.8% and blood alcohol was detected in 27.7% of the patients among our study population. The patients in the alcohol-positive group had higher mortality rate, higher clotting time, and lower maximum lysis, more fibrinolysis shutdown, and hyperfibrinolysis than those in the alcohol-negative group. In logistic regression analysis, blood alcohol was independently associated with in-hospital mortality (odds ratio [OR] 2.578; 95% confidence interval [CI], 1.550–4.288) and fibrinolysis shutdown (OR 1.883 [95% CI, 1.286–2.758]). Within the fibrinolysis shutdown group, blood alcohol was an independent predictor of mortality (OR 2.168 [95% CI, 1.030–4.562]). Conclusions Alcohol is an independent risk factor for mortality and fibrinolysis shutdown in trauma patients. Further, alcohol is an independent risk factor for mortality among patients who experienced fibrinolysis shutdown.

scholarly journals New-onset atrial fibrillation in critically ill patients with coronavirus disease 2019 (COVID-19)

2021 ◽  
Author(s):  
BİŞAR ERGÜN ◽  
BEGUM ERGAN ◽  
Melih Kaan SÖZMEN ◽  
Mehmet Nuri YAKAR ◽  
Murat KÜÇÜK ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Intensive Care Unit ◽  
Risk Factor ◽  
Intensive Care ◽  
Hospital Mortality ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Independent Risk Factor ◽  
Onset Atrial Fibrillation ◽  
New Onset

Abstract Objectives: To determine the incidence, risk factors, and outcomes of new-onset atrial fibrillation (NOAF) in a cohort of critically ill patients with coronavirus disease 2019 (COVID-19). Methods: We conducted a retrospective study on patients admitted to the intensive care unit (ICU) with a diagnosis of COVID-19. NOAF was defined as atrial fibrillation that was detected after diagnosis of COVID-19 without a prior history. The primary outcome of the study was the effect of NOAF on mortality in critically ill COVID-19 patients. Results: We enrolled 248 eligible patients. NOAF incidence was 14.9% (n=37), and 78% of patients (n=29) were men in NOAF positive group. Median age of the NOAF group was 79.0 (interquartile range, 71.5-84.0). Hospital mortality was higher in the NOAF group (87% vs 67%, respectively, p=0.019). However, in multivariate analysis, NOAF was not an independent risk factor for hospital mortality (OR 1.42, 95% CI 0.40–5.09, p=0.582) Conclusions: The incidence of NOAF was 14.9% in critically ill COVID-19 patients. Hospital mortality was higher in the NOAF group. However, NOAF was not an independent risk factor for hospital mortality in patients with COVID-19. Keywords: Atrial fibrillation, critical care, intensive care unit, COVID-19, mortality, hospital mortality

Abstract 066: Perioperative Stroke as a Predictor of Mortality and Morbidity in Patients Undergoing CABG

2017 ◽  
Vol 10 (suppl_3) ◽  
Author(s):  
Amol Mehta
Keyword(s):  
Risk Factor ◽  
Hospital Mortality ◽  
Independent Risk Factor ◽  
Financial Burden ◽  
Strong Predictor ◽  
Large Population ◽  
Risk Category ◽  
Mortality And Morbidity ◽  
Perioperative Stroke ◽  
Risk Of Death

Background: Perioperative stroke is a devastating neurological complication of Coronary Artery Bypass Grafting surgery (CABG). It results in significantly increased rates of mortality and morbidity and presents a significant financial burden to our healthcare system. It has not, however, been studied in a large population based sample. We aim to investigate the role of perioperative stroke as an independent risk factor for in-hospital mortality and morbidity following CABG, and to review trends in the early outcomes of CABG from the years 1999-2011. Hypothesis: Perioperative stroke is an independent risk factor for in-hospital mortality and morbidity following CABG. Methods: Data from the 1999-2011 Nationwide Inpatient Sample was analyzed. We identified patients who underwent CABG using ICD-9 and CCS codes, excluding patients undergoing concomitant heart and or vascular procedures, and also excluding patients below the age of 18 and above the age of 100. Results: Analysis on our sample of 668,627 patients yielded an overall rate of perioperative stroke, mortality, and morbidity of 1.87%, 2.13%, and 49.07%, respectively. Along with age, risk category, gender, and other postoperative outcomes, perioperative stroke was found to be a strong predictor of mortality and morbidity, leading to more than a 5-fold risk of death and morbidity. Conclusions: Perioperative stroke remains a serious adverse outcome of CABG and is an independent predictor of mortality and morbidity. While rates of stroke and mortality are decreasing, morbidity continues to trend upwards. This study emphasizes the importance of prevention and early intervention in patients at risk for perioperative stroke.

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