scholarly journals Prevalences of and risk factors for biliary stones and gallbladder polyps in a large Chinese population

HPB ◽  
2012 ◽  
Vol 14 (6) ◽  
pp. 373-381 ◽  
Author(s):  
Qing Xu ◽  
Lian-yuan Tao ◽  
Qiao Wu ◽  
Fei Gao ◽  
Feng-liang Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chinese Population ◽  
Biliary Stones ◽  
Gallbladder Polyps

scholarly journals Male gender and obesity are risk factors of gallbladder polyps in a large northwest Chinese population

2021 ◽  
Author(s):  
Yao Liu ◽  
Jiajing Yin ◽  
Shen Qu
Keyword(s):  
Risk Factors ◽  
Chinese Population ◽  
Blood Lipids ◽  
Demographic Characteristic ◽  
Northwest China ◽  
Serum Biochemistry ◽  
Male Gender ◽  
Chinese People ◽  
Gallbladder Polyps ◽  
Related Risk

Abstract Objectives The aim of this study was to determine the prevalence and related risk factors of gallbladder polyps in a northwest Chinese population. Methods A retrospective investigation was conducted on the prevalence and risk factors of gallbladder polyps among subjects who underwent physical examination in Shanxi Harmony Healthy Examination Center, from January 2016 to December 2020. Demographic, serum biochemistry, and ultrasonography data were collected from all patients. The correlations between the prevalence of gallbladder polyps and sex, age, body mass index (BMI), serum biochemistry, liver viral markers were calculated for all patients. Results A total of 67438 people aged from 18 to 75 years were enrolled in the study. Overall prevalence of gallbladder polyps in northwest China was approximately 7.8% and with the highest prevalence among middle-aged men. Analysis risk factors for increased odds ratios (ORs) of gallbladder polyps development were female (OR = 0.746; 95%CI, 0.624–0.891, P = 0.001) and BMI(25-27.5kg/m2) (OR = 1.243; 95%CI, 1.035–1.494, P = 0.020), BMI(≥ 27.5 kg/m2) (OR = 1.274; 95%CI, 1.038–1.562, P = 0.020). Other demographic characteristic and serum biochemistry parameters, including blood pressure, blood lipids, liver and renal function, liver viral markers did not correlate with the prevalence of gallbladder polyps. Conclusions Prevalence of gallbladder polyps among northwest Chinese people are a little higher to those reported for other populations. Male gender and BMI were strong risk factors for gallbladder polyps formation.

scholarly journals The albumin-to-alkaline phosphatase ratio as an independent predictor of future non-alcoholic fatty liver disease in a 5-year longitudinal cohort study of a non-obese Chinese population

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Guotai Sheng ◽  
Nan Peng ◽  
Chong Hu ◽  
Ling Zhong ◽  
Mingchun Zhong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Fatty Liver Disease ◽  
Chinese Population ◽  
Independent Predictor ◽  
Multiple Regression Model ◽  
Obese People ◽  
Alcoholic Fatty Liver ◽  
Obese Subjects ◽  
Alcoholic Fatty Liver Disease

Abstract Background The albumin-to-alkaline phosphatase ratio (AAPR) is a newly developed index of liver function, but its association in patients with non-alcoholic fatty liver disease (NAFLD) has not been established. The aim of this study was to investigate the association between the AAPR and NAFLD in a non-obese Chinese population. Methods The study included 10,749 non-obese subjects without NAFLD at baseline and divided them into quintiles according to the AAPR. A Cox multiple regression model was used to examine the association between the AAPR and its quintiles and the incidence of NAFLD. Results The average age of the study population was 43.65 ± 15.15 years old. During the 5-year follow-up, 1860 non-obese subjects had NAFLD events. In the Cox multiple regression model, after adjusting the model according to important risk factors, the AAPR and NAFLD risk were independently correlated, and with a gradual increase in the AAPR, the NAFLD risk decreased gradually (HR: 0.61, 95% CI: 0.47, 0.81; P-trend< 0.0001). Additionally, there were significant interactions between the AAPR and BMI, blood pressure and lipids (P-interaction < 0.05). Stratified analysis showed that the risk of AAPR-related NAFLD decreased in people with normal blood pressure and lipid levels, while the risk of AAPR-related NAFLD increased abnormally in people who were underweight. Conclusions This longitudinal cohort study provides the first evidence that the AAPR is an independent predictor of future NAFLD events in non-obese people. For non-obese people with a low AAPR, especially those with BMI < 18.5 kg/m2, more attention should be given to the management of risk factors for NAFLD to prevent future NAFLD.

scholarly journals Genetic Variants Associated with Myocardial Infarction and the Risk Factors in Chinese Population

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e86332 ◽  
Author(s):  
Yongqin Wang ◽  
Lefeng Wang ◽  
Xin Liu ◽  
Yongzhi Zhang ◽  
Liping Yu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Genetic Variants ◽  
Chinese Population

scholarly journals Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Bo Song ◽  
Yamei Wang ◽  
Xiuzhi Zhu ◽  
Li Zhang ◽  
Hui Zhou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Chinese Population ◽  
Han Chinese ◽  
Preventive Strategy ◽  
Diabetes Surgery ◽  
Han Chinese Population ◽  
Related Data ◽  
Significant Difference ◽  
Thrombotic Diseases

The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enrolled. The relevant data for the participants, including general information (gender, age, smoking, and drinking), comorbidities (diabetes, hypertension, and anemia), tumor-related data (tumor site, histology, degree of differentiation, and clinical stage), and treatment-related data (surgery, chemotherapy, hormones, transfusion, and peripherally inserted central venous catheter (PICC)), were collected. Statistically significant factors derived from univariate analyses were then subjected to multivariate logistic regression analyses. The results demonstrate a statistically significant difference in age, diabetes, hypertension, histology, surgery, chemotherapy, and PICC ( P < 0.05 ), compared with control. Age, diabetes, surgery, and PICC serve as independent risk factors for GC-associated thrombotic diseases ( P < 0.05 ). The present work demonstrates that GC-associated thrombotic diseases are significantly associated with age, diabetes, surgery, and PICC, suggesting a potential target for early detection and preventive strategy for GC patients with thrombophilia.

scholarly journals Prevalence and risk factors of prolonged corrected QT interval in general Chinese population

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Qun Ma ◽  
Zhao Li ◽  
Xiaofan Guo ◽  
Liang Guo ◽  
Shasha Yu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rural Areas ◽  
Chinese Population ◽  
Liaoning Province ◽  
Qtc Interval ◽  
Qtc Prolongation ◽  
Cvd Risk ◽  
Specific Risk ◽  
Increased Risk ◽  
General Chinese Population

Abstract Background Corrected QT (QTc) interval has been correlated with total and CVD mortality. Although much is known about the relation between prolonged QTc interval and clinical outcome, there is no information on the prevalence and specific risk factors of QTc prolongation in general Chinese population. We evaluated the prevalence of prolonged QTc interval and its risk factors in general Chinese population, aiming to fill in the gaps in the literature and provide evidence for potential CVD risk prediction and disease burden estimate in community. Methods A population-based survey was conducted on 11,209 participants over the age of 35 in rural areas of Liaoning Province from 2012 to 2013. Twelve-lead ECGs and automatic analysis were performed on all participants. Logistic regression adjustments were made by using the Bazett’s formula to correlate specific risk factors with prolonged QTc intervals (> 440 ms) for potential confounders. Results The overall prevalence of prolonged QTc interval was 31.6%. The prevalence increased significantly with age (24.1% among those aged 35–44 years; 28.3%, 45–54 years; 35.2%, 55–64 years; 43.4%, ≥65 years, P < 0.001). Participants with a history of CVD had a higher prevalence of QTc prolongation (40.7% vs. 30.0%). In the fully adjusted logistic regress model, older age, abdominal obesity, hypertension, diabetes, hypokalemia and any medicine used in the past two weeks were associated independently with increased risk for prolonged QTc interval (All P < 0.05). We found no significant differences between general obesity, hypocalcemia and hypomagnesemia with prolongation of QTc interval. Female sex showed opposite results after applying clinical diagnostic criteria, and high physical activity could reduce the risk of prolonged QTc interval. Conclusions The prevalence of prolonged QTc interval was relatively high in general Chinese population and listed relevant factors, which would help identify patients at risk in pre-clinical prevention and provide evidence for estimating potential CVD burden and making management strategies in community.

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