THYMOSIN IN THE EARLY DIAGNOSIS AND TREATMENT OF HIGH RISK HOMOSEXUALS AND HEMOPHILIACS WITH AIDS-LIKE IMMUNE DYSFUNCTION

1984 ◽  
Vol 437 (1 Acquired Immu) ◽  
pp. 88-97 ◽  
Author(s):  
Paul H. Naylor ◽  
Richard S. Schulof ◽  
Marcelo B. Sztein ◽  
Thomas J. Spira ◽  
Paul R. McCurdy ◽  
...  
Keyword(s):  
High Risk ◽  
Early Diagnosis ◽  
Immune Dysfunction ◽  
Diagnosis And Treatment

scholarly journals Aggressive Posterior Retinopathy of Prematurity (AP-ROP)

2018 ◽  
pp. 63-68
Keyword(s):  
High Risk ◽  
Early Diagnosis ◽  
Laser Treatment ◽  
Premature Infants ◽  
Retinopathy Of Prematurity ◽  
Clinical Course ◽  
Clinical Findings ◽  
Posterior Pole ◽  
Diagnosis And Treatment ◽  
Preterm Babies

Aggressive retinopathy of prematurity (AP-ROP) has subtle clinical findings that may preclude early diagnosis and treatment. Premature infants with AP-ROP have a progressive clinical course and may benefit from early laser treatment. Although subjective in nature, plus disease, and any posterior pole changes especially at the border of the vascular and avascular retina should be carefully evaluated, keeping AP-ROP in mind in especially high-risk preterm babies.

Galactosaemia

1987 ◽  
Vol 5 (3-4) ◽  
pp. 175-188 ◽  
Author(s):  
L B. Sardharwalla ◽  
J. E. Wraith
Keyword(s):  
High Risk ◽  
Early Diagnosis ◽  
Mental Development ◽  
Diagnosis And Treatment ◽  
Early Age ◽  
Biochemical Genetics ◽  
Classical Galactosaemia ◽  
Eventual Outcome ◽  
Very High

This paper reviews galactosaemia and describes the experience of the Willink Biochemical Genetics Unit in the management of classical galactosaemia. Galactokinase and UDPgalactose-4-epimerase deficiency are dealt with briefly. The former disorder is readily treated with a galactose free diet and if this is started early in life, the only complication, cataracts, is avoided. Epimerase deficiency is a relatively ‘new’ disorder and little is known about the eventual outcome of affected patients. Early observations suggest that the prognosis is likely to be poor even in those patients diagnosed and treated soon after birth. Classical galactosaemia leads to a number of long term complications. The prognosis for normal mental development in affected patients is poor. Unfortunately this does not appear to be reversible by early diagnosis and treatment and whilst every effort should be made to establish an early diagnosis our experience suggests that there is no difference in the ultimate mental development between those who are detected within the first two weeks of life and those before the age of six weeks. In addition female homozygotes are at a very high risk of developing ovarian failure at an early age.

scholarly journals Infective Endocarditis in a Neonate

2018 ◽  
Vol 37 (3) ◽  
pp. 286-289
Author(s):  
Sangita Puree Dhungana ◽  
Sabina Shrestha ◽  
Sujit Kumar Shrestha
Keyword(s):  
Intensive Care ◽  
Infective Endocarditis ◽  
High Risk ◽  
Early Diagnosis ◽  
Bacterial Endocarditis ◽  
Diagnosis And Treatment ◽  
Fatal Disease ◽  
Intensive Care Monitoring

Bacterial endocarditis in neonates is a rare. Generally neonates who develop endocarditis have required the invasive intensive care monitoring necessary for the support and treatment of a high-risk nursery population.  Neonatal Infective endocarditis is usually reported as a fatal disease. With early diagnosis and treatment we can change prognosis to better side.

scholarly journals Congenital cerebriform intradermal nevus presenting as cutis verticis gyrata: a case report

2018 ◽  
Vol 6 (10) ◽  
pp. 3461
Author(s):  
Ashish Jawarkar ◽  
Bhumika J. Gharia ◽  
Amrish N. Shah
Keyword(s):  
Case Report ◽  
High Risk ◽  
Malignant Melanoma ◽  
Early Diagnosis ◽  
Rare Disorder ◽  
Diagnosis And Treatment ◽  
Cutis Verticis Gyrata ◽  
Secondary Form ◽  
Intradermal Nevus ◽  
The Brain

Cerebriform intradermal nevus is a rare disorder characterised by development of folds and furrows on the scalp, giving it a convoluted appearance resembling surface of the brain. There are two main forms of CVG, primary and secondary. Secondary form may appear at any age and is usually secondary to causes such as tumors, Cerebriform intradermal nevus (CIN), neurofibromas or amyloidosis. There is high risk of development of malignant melanoma in patients of CIN presenting as CVG. Hence early diagnosis and treatment is important.

scholarly journals Osteoporosis: Current state of the art

2017 ◽  
Vol 89 (5) ◽  
pp. 90-97 ◽  
Author(s):  
A F Verbovoy ◽  
A V Pashentseva ◽  
L A Sharonova
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Early Diagnosis ◽  
State Of The Art ◽  
Diagnosis And Treatment ◽  
Current Strategy ◽  
Current State ◽  
High Prevalence ◽  
Significant Mortality

As of now, osteoporosis (OP) is one of the most important sociomedical problems because of its high prevalence and resultant disability, as well as significant mortality attributable to complications. The current strategy for providing care for patients of OP is its early diagnosis, by determining the high risk of fractures, and early pathogenetic treatment. The article gives an update on the epidemiology, risk factors, diagnosis, and treatment of OP.

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