Functional Foods: Mechanisms of Action on Immunocompetent Cells

Nutraceuticals have sparked great attention because of their perceived safety, The current article focuses on the need for appropriate diets, health issues associated with failure to adhere to the known healthy eating models, development of new nutraceuticals/functional foods/food supplements with novel health benefits, elucidation mechanisms of action of these products, and to define and understand the analytical, challenges during the formulation of different dosage form, current scenario in India, future and regulatory aspects of nutraceuticals. the Indian industry and regulatory scenario are relatively nascent and have great potential to develop and compete with other international agencies. This is a rapidly growing industry in India and several initiatives have been taken in this direction to make India one of the key future players in the area of nutraceuticals. This article can help you stay up to date on the latest advancements in nutraceutical research.

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Antioxidant Diets and Functional Foods Promote Healthy Aging and Longevity Through Diverse Mechanisms of Action

The Role of Functional Food Security in Global Health ◽

10.1016/b978-0-12-813148-0.00032-3 ◽

2019 ◽

pp. 541-563

Author(s):

Sanit Wichansawakun ◽

Harpal S. Buttar

Keyword(s):

Healthy Aging ◽

Functional Foods ◽

Mechanisms Of Action

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Dietary Soy Isoflavone: A Mechanistic Insight

Natural Product Communications ◽

10.1177/1934578x1701200439 ◽

2017 ◽

Vol 12 (4) ◽

pp. 1934578X1701200 ◽

Cited By ~ 4

Author(s):

Renu Chadha ◽

Yashika Bhalla ◽

Ankita Jain ◽

Kunal Chadha ◽

Maninder Karan

Keyword(s):

Protective Effect ◽

Chronic Diseases ◽

Functional Foods ◽

Health Benefits ◽

Mechanisms Of Action ◽

Soy Isoflavones ◽

Future Research ◽

Soy Isoflavone ◽

Mechanistic Insight ◽

Nutraceutical Properties

Soy, a major component of the diet for centuries contains the largest concentration of isoflavones, a class of phytoestrogens. A variety of health benefits are associated with the consumption of soy primarily because of the isoflavones genistein, daidzein, and glycitein with a potential protective effect against a number of chronic diseases. Owing to the pharmaceutical and nutraceutical properties allied with isoflavonoids and their use in functional foods, there is a growing interest in these compounds. This review throws light on the chemistry, and significant pharmacological and biopharmaceutical aspects of soy isoflavones. This article critically describes the mechanisms of action, infers conclusions and shows opportunity for future research.

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Phytotherapy for colorectal cancer: about some phytochemicals and their mechanisms of action]

Medicinal Plant Communications ◽

10.37360/mpc.20.3.3.15 ◽

2020 ◽

Vol 3 (4) ◽

pp. 79-84

Author(s):

Patricia Landazuri ◽

◽

Beatriz Restrepo ◽

Nelsy Loango ◽

◽

...

Keyword(s):

Colorectal Cancer ◽

Cancer Cells ◽

Signaling Pathways ◽

Intestinal Microbiota ◽

Functional Foods ◽

Molecular Targets ◽

Mechanisms Of Action ◽

Inflammatory Signaling ◽

Men And Women ◽

Prevention And Treatment

Colorectal cancer (CRC) is very common in both men and women. Phytochemicals such as polysaccharide alkaloids, polyphenols, diterpenoids among others, have been used for the prevention and treatment of cancer. The mechanisms of action of these compounds on cancer cells include molecular targets in the apoptosis, proliferation, metastasis and anti-inflammatory signaling pathways. At the level of the whole organism, they improve the intestinal microbiota, which plays an important role in the initiation and progression of CRC. Recent research is aimed at obtaining and modifying phytochemicals to improve their effectiveness, safety and their inclusion in functional foods, but more studies are needed to validate their properties.

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Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe)

Foods ◽

10.3390/foods8060185 ◽

2019 ◽

Vol 8 (6) ◽

pp. 185 ◽

Cited By ~ 48

Author(s):

Qian-Qian Mao ◽

Xiao-Yu Xu ◽

Shi-Yu Cao ◽

Ren-You Gan ◽

Harold Corke ◽

...

Keyword(s):

Phenolic Compounds ◽

Bioactive Compounds ◽

Functional Foods ◽

Review Paper ◽

Current Knowledge ◽

Biological Activities ◽

Chemical Constituents ◽

Zingiber Officinale ◽

Mechanisms Of Action ◽

Zingiber Officinale Roscoe

Ginger (Zingiber officinale Roscoe) is a common and widely used spice. It is rich in various chemical constituents, including phenolic compounds, terpenes, polysaccharides, lipids, organic acids, and raw fibers. The health benefits of ginger are mainly attributed to its phenolic compounds, such as gingerols and shogaols. Accumulated investigations have demonstrated that ginger possesses multiple biological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer, neuroprotective, cardiovascular protective, respiratory protective, antiobesity, antidiabetic, antinausea, and antiemetic activities. In this review, we summarize current knowledge about the bioactive compounds and bioactivities of ginger, and the mechanisms of action are also discussed. We hope that this updated review paper will attract more attention to ginger and its further applications, including its potential to be developed into functional foods or nutraceuticals for the prevention and management of chronic diseases.

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Diet Quality, a Term Subject to Change over Time

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000104 ◽

2012 ◽

Vol 82 (3) ◽

pp. 144-147 ◽

Cited By ~ 5

Author(s):

Ibrahim Elmadfa ◽

Alexa L. Meyer

Keyword(s):

Diet Quality ◽

Functional Foods ◽

Disease Risk ◽

Well Being ◽

Industrialized Countries ◽

Quality Factors ◽

Long Time ◽

Quality Diet ◽

Important Quality ◽

Health And Well Being

A high-quality diet is one of the foundations of health and well-being. For a long time in human history, diet was chiefly a source of energy and macronutrients meant to still hunger and give the strength for work and activities that were in general much harder than nowadays. Only few persons could afford to emphasize enjoyment. In the assessment of quality, organoleptic properties were major criteria to detect spoilage and oxidative deterioration of food. Today, food hygiene is a quality aspect that is often taken for granted by consumers, despite its lack being at the origin of most food-borne diseases. The discovery of micronutrients entailed fundamental changes of the concept of diet quality. However, non-essential food components with additional health functions were still barely known or not considered important until recently. With the high burden of obesity and its associated diseases on the rise, affluent, industrialized countries have developed an increased interest in these substances, which has led to the development of functional foods to optimize special body functions, reduce disease risk, or even contribute to therapeutic approaches. Indeed, nowadays, high contents of energy, fat, and sugar are factors associated with a lower quality of food, and products with reduced amounts of these components are valued by many consumers. At the same time, enjoyment and convenience are important quality factors, presenting food manufacturers with the dilemma of reconciling low fat content and applicability with good taste and appealing appearance. Functional foods offer an approach to address this challenge. Deeper insights into nutrient-gene interactions may enable personalized nutrition adapted to the special needs of individuals. However, so far, a varied healthy diet remains the best basis for health and well-being.

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Case Formulation and Design of Behavioral Treatment Programs

European Journal of Psychological Assessment ◽

10.1027//1015-5759.19.3.164 ◽

2003 ◽

Vol 19 (3) ◽

pp. 164-174 ◽

Cited By ~ 27

Author(s):

Stephen N. Haynes ◽

Andrew E. Williams

Keyword(s):

Functional Analysis ◽

Behavior Problems ◽

Behavioral Treatment ◽

Clinical Case ◽

Relative Magnitude ◽

Mechanisms Of Action ◽

Treatment Programs ◽

Case Formulation ◽

Functional Relations ◽

Causal Variables

Summary: We review the rationale for behavioral clinical case formulations and emphasize the role of the functional analysis in the design of individualized treatments. Standardized treatments may not be optimally effective for clients who have multiple behavior problems. These problems can affect each other in complex ways and each behavior problem can be influenced by multiple, interacting causal variables. The mechanisms of action of standardized treatments may not always address the most important causal variables for a client's behavior problems. The functional analysis integrates judgments about the client's behavior problems, important causal variables, and functional relations among variables. The functional analysis aids treatment decisions by helping the clinician estimate the relative magnitude of effect of each causal variable on the client's behavior problems, so that the most effective treatments can be selected. The parameters of, and issues associated with, a functional analysis and Functional Analytic Clinical Case Models (FACCM) are illustrated with a clinical case. The task of selecting the best treatment for a client is complicated because treatments differ in their level of specificity and have unequally weighted mechanisms of action. Further, a treatment's mechanism of action is often unknown.

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