Root membrane lipids as potential biomarkers to discriminate silage‐corn genotypes cultivated on podzolic soils in boreal climate

2020 ◽  
Vol 170 (3) ◽  
pp. 440-450
Author(s):  
Muhammad Nadeem ◽  
Raymond Thomas ◽  
Oludoyin Adigun ◽  
Charles Manful ◽  
Jiaxu Wu ◽  
...  
Keyword(s):  
Membrane Lipids ◽  
Podzolic Soils ◽  
Boreal Climate ◽  
Potential Biomarkers

P.115 Membrane lipids in early phases of psychosis: potential biomarkers for a personalised medicine?

2021 ◽  
Vol 44 ◽  
pp. S11-S12
Author(s):  
A. Frajerman ◽  
B. Chaumette ◽  
A. Lamazière ◽  
C. Tessier ◽  
P. Nuss ◽  
...  
Keyword(s):  
Membrane Lipids ◽  
Personalised Medicine ◽  
Early Phases ◽  
Potential Biomarkers

The organization of cell surface membrane domains

1989 ◽  
Vol 47 ◽  
pp. 804-805
Author(s):  
Michael Edidin
Keyword(s):  
Cell Surface ◽  
Membrane Lipids ◽  
Surface Membrane ◽  
Lateral Diffusion ◽  
Cell Types ◽  
Membrane Domains ◽  
Membrane Biology ◽  
Morphological Polarity ◽  
Discrete Domains ◽  
Membrane Components

Cell surface membranes are based on a fluid lipid bilayer and models of the membranes' organization have emphasised the possibilities for lateral motion of membrane lipids and proteins within the bilayer. Two recent trends in cell and membrane biology make us consider ways in which membrane organization works against its inherent fluidity, localizing both lipids and proteins into discrete domains. There is evidence for such domains, even in cells without obvious morphological polarity and organization [Table 1]. Cells that are morphologically polarised, for example epithelial cells, raise the issue of membrane domains in an accute form.The technique of fluorescence photobleaching and recovery, FPR, was developed to measure lateral diffusion of membrane components. It has also proven to be a powerful tool for the analysis of constraints to lateral mobility. FPR resolves several sorts of membrane domains, all on the micrometer scale, in several different cell types.

Melatonin reduces high levels of lipid peroxidation induced by potassium iodate in porcine thyroid

2019 ◽  
pp. 1-7 ◽  
Author(s):  
Paulina Iwan ◽  
Jan Stepniak ◽  
Malgorzata Karbownik-Lewinska
Keyword(s):  
Lipid Peroxidation ◽  
Oxidative Damage ◽  
Membrane Lipids ◽  
Chemical Properties ◽  
Iodine Concentration ◽  
Free Radical Scavenger ◽  
Radical Scavenger ◽  
Protective Effects ◽  
Potassium Iodate ◽  
Hormone Synthesis

Abstract. Iodine is essential for thyroid hormone synthesis. Under normal iodine supply, calculated physiological iodine concentration in the thyroid is approx. 9 mM. Either potassium iodide (KI) or potassium iodate (KIO3) are used in iodine prophylaxis. KI is confirmed as absolutely safe. KIO3 possesses chemical properties suggesting its potential toxicity. Melatonin (N-acetyl-5-methoxytryptamine) is an effective antioxidant and free radical scavenger. Study aims: to evaluate potential protective effects of melatonin against oxidative damage to membrane lipids (lipid peroxidation, LPO) induced by KI or KIO3 in porcine thyroid. Homogenates of twenty four (24) thyroids were incubated in presence of either KI or KIO3 without/with melatonin (5 mM). As melatonin was not effective against KI-induced LPO, in the next step only KIO3 was used. Homogenates were incubated in presence of KIO3 (200; 100; 50; 25; 20; 15; 10; 7.5; 5.0; 2.5; 1.25 mM) without/with melatonin or 17ß-estradiol. Five experiments were performed with different concentrations of melatonin (5.0; 2.5; 1.25; 1.0; 0.625 mM) and one with 17ß-estradiol (1.0 mM). Malondialdehyde + 4-hydroxyalkenals (MDA + 4-HDA) concentration (LPO index) was measured spectrophotometrically. KIO3 increased LPO with the strongest damaging effect (MDA + 4-HDA level: ≈1.28 nmol/mg protein, p < 0.05) revealed at concentrations of around 15 mM, thus corresponding to physiological iodine concentrations in the thyroid. Melatonin reduced LPO (MDA + 4-HDA levels: from ≈0.97 to ≈0,76 and from ≈0,64 to ≈0,49 nmol/mg protein, p < 0.05) induced by KIO3 at concentrations of 10 mM or 7.5 mM. Conclusion: Melatonin can reduce very strong oxidative damage to membrane lipids caused by KIO3 used in doses resulting in physiological iodine concentrations in the thyroid.

Membrane Lipids of Prokaryotes

1982 ◽  
Keyword(s):  
Membrane Lipids

Transcriptional Analysis identifies long non-coding RNAs as potential biomarkers in pneumonia and COPD exacerbation

2020 ◽  
Author(s):  
W Bertrams ◽  
K Griss ◽  
M Han ◽  
K Seidel ◽  
A Klemmer ◽  
...  
Keyword(s):  
Transcriptional Analysis ◽  
Copd Exacerbation ◽  
Non Coding Rnas ◽  
Potential Biomarkers

Orientation of processes of biological nitrogen transformation in winter rye agroecosystems under different levels of fertilization background

2016 ◽  
Vol 3 (3) ◽  
pp. 28-34
Author(s):  
V. Volkogon ◽  
I. Korotka
Keyword(s):  
Root Zone ◽  
Field Studies ◽  
Nitrogen Transformation ◽  
Mineral Nitrogen ◽  
Nitrogen Fertilizers ◽  
Winter Rye ◽  
Podzolic Soils ◽  
Microbial Preparation ◽  
Biological Nitrogen

Aim. To determine physiologically expedient rates of mineral nitrogen in winter rye production on sod-podzol- ic soils based on the orientation of the processes of biological nitrogen transformation in the plants rhizosphere. Methods. Field studies, gas chromatography determination of potential nitrogen fi xation activity and potential emissions of N 2 O. Results. The results obtained have demonstrated that the rates of mineral nitrogen, not ex- ceeding 60 kg/ha, can be considered physiologically expedient for winter rye production on sod-podzolic soils. Under the application of microbial preparation Diazobakteryn, there is a higher physiological need of plants for nitrogen, which allows increasing the rates of nitrogen fertilizers up to 90 kg/ha. Conclusions. The orienta- tion of the processes of biological nitrogen transformation in the root zone of plants is a reliable indicator of determining the appropriateness of nitrogen fertilization of crops.

Cumulus Cell Genes as Potential Biomarkers for the Diagnosis of the Quality of Oocytes and Embryos

2017 ◽  
Vol 8 (1) ◽  
pp. 91-98
Author(s):  
Olena A. Shepel ◽  
Tetyana Yu. Voznesenska ◽  
Taras V. Blashkiv ◽  
Roman I. Yanchii
Keyword(s):  
Cumulus Cell ◽  
Potential Biomarkers

1884-P: Serum ANGPTL2, ANGPTL3, and ANGPTL4 as Potential Biomarkers for Diagnosis of Nonalcoholic Fatty Liver Disease

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1884-P
Author(s):  
YAN MA ◽  
YAN WANG ◽  
XIN WANG ◽  
LONGYAN YANG ◽  
JIANAN LANG ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver ◽  
Potential Biomarkers

Role of exosomes in diagnosis and therapy of prostate cancer

2020 ◽  
Vol 28 (3) ◽  
pp. 399-405
Author(s):  
Fabrizio Fontana ◽  
Olga A. Babenko
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Tumor Cells ◽  
Biological Fluids ◽  
Diagnosis And Treatment ◽  
Diagnosis And Therapy ◽  
The Future ◽  
Important Direction ◽  
Potential Biomarkers

Aim of this letter is to attract the attention of journal readers to the study of exosomes as an important direction in the development of Oncology, in particular, in the diagnosis and treatment of prostate cancer. Exosomes are produced by tumor cells and regulate proliferation, metastasis, and the development of chemoresistance. Their extraction from biological fluids allows further use of these vesicles as potential biomarkers of prostate cancer. In the future, exosomes can be successfully used in the delivery of drugs and other anti-tumor substances to cancer cells.

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