Bio-Heat Transfer Model of Human Eye Subjected to Retinal Laser Irradiation

Author(s):  
Arunn Narasimhan ◽  
Kaushal Kumar Jha

Retinopathy is a surgical process in which maladies of the human eye are treated by laser irradiation. A two-dimensional numerical model of the human eye geometry has been developed to investigate steady and transient thermal effects due to laser radiation. In particular, the influence of choroidal pigmentations and choroidal blood convection — parameterized as a function of choroidal blood perfusion are investigated in detail. The Pennes bio-heat transfer equation is invoked as the governing equation and a finite volume formulation is employed in the numerical method. The numerical model is validated with available experimental and two-dimensional numerical results. For a 500 μm diameter spot size, laser power of 0.2 W, with 100% absorption of laser radiation in the Retinal Pigmented Epithelium (RPE) region, the peak RPE temperature is observed to be 175 °C at steady state, with no blood perfusion in choroid. It reduces to 168.5 °C when the choroidal blood perfusion rate is increased to 23.3 kgm−3s−1. However, under transient simulations, the peak RPE temperature is observed to remain constant at 104 °C after 100 ms of the laser surgery period. A truncated three-dimensional model incorporating multiple laser irradiation spots is also developed to observe the spatial effect of choroidal blood perfusion. For a circular array of seven uniformly distributed spots of identical diameter and laser power of 0.2 W, steady and transient temperature evolution are presented with analysis.

2021 ◽  
Author(s):  
Dasith Liyanage ◽  
Suk-Chun Moon ◽  
Ajith S. Jayasekare ◽  
Abheek Basu ◽  
Madeleine Du Toit ◽  
...  

Abstract High-temperature laser-scanning confocal microscopy (HT-LSCM) has proven to be an excellent experimental technique through in-situ observations of high temperature phase transformation to study kinetics and morphology using thin disk steel specimens. A 1.0 kW halogen lamp, within the elliptical cavity of the HT-LSCM furnace radiates heat and imposes a non-linear temperature profile across the radius of the steel sample. This local temperature profile when exposed at the solid/liquid interface determines the kinetics of solidification and phase transformation morphology. A two-dimensional numerical heat transfer model for both isothermal and transient conditions is developed for a concentrically solidifying sample. The model can accommodate solid/liquid interface velocity as an input parameter under concentric solidification with cooling rates up to 100 K/min. The model is validated against a commercial finite element analysis software package, Strand7, and optimized with experimental data obtained under near-to equilibrium conditions. The validated model can then be used to define the temperature landscape under transient heat transfer conditions.


1989 ◽  
Vol 111 (1) ◽  
pp. 41-45 ◽  
Author(s):  
A. Zebib ◽  
Y. K. Wo

Thermal analysis of forced air cooling of an electronic component is modeled as a two-dimensional conjugate heat transfer problem. The velocity field in a constricted channel is first computed. Then, for a typical electronic module, the energy equation is solved with allowance for discontinuities in the thermal conductivity. Variation of the maximum temperature with the average air velocity is presented. The importance of our approach in evaluating possible benefits due to changes in component design and the limitations of the two-dimensional model are discussed.


2020 ◽  
Author(s):  
Myo Min Zaw ◽  
Manpreet Singh ◽  
Ronghui Ma ◽  
Liang Zhu

In this study, we first develop a whole body model based on measurements of a human body, with realistic boundary conditions incorporated before and after a person jumps into a hot tub. For the transient heat transfer simulation, the initial condition is the established steady state temperature field of the human body with appropriate clothing layer to ensure the thermal equilibrium of the body with its surroundings. Once the person is inside a hot tub, the Pennes bioheat equation is used to simulate the transient temperature elevations of the body, and the rising of the arterial blood temperature is solved by an energy balance equation modeling thermal exchange between body tissue and the blood in the body. The safe duration of soaking in hot tubs is then determined as affected by the hot tub water temperatures.


1987 ◽  
Vol 109 (3) ◽  
pp. 218-225 ◽  
Author(s):  
R. Kress ◽  
R. Roemer

The object of this study was to devise a unified method for comparing different thermal techniques for the estimation of blood perfusion rates and to perform a comparison for several common techniques. The approach used was to develop analytical models for the temperature response for all combinations of five power deposition geometries (spherical, one- and two-dimensional cylindrical, and one- and two-dimensional Gaussian) and three transient heating techniques (temperature pulse-decay, temperature step function, and constant-power heat-up) plus one steady-state heating technique. The transient models were used to determine the range of times (the time window) when a significant portion of the transient temperature response was due to blood perfusion. This time window was defined to begin when the difference between the conduction-only and the conduction-plus-blood flow transient temperature (or power) responses exceeded a specified value, and to end when the conduction-plus-blood flow transient temperature (or power) reached a specified fraction of its steady-state value. The results are summarized in dimensionless plots showing the size of the time windows for each of the transient perfusion estimation techniques. Several conclusions were drawn, in particular: (a) low perfusions are difficult to estimate because of the dominance of conduction, (b) large heated regions are better suited for estimation of low perfusions, (c) noninvasive heating techniques are superior because they have the potential to minimize conduction effects, and (d) none of the transient techniques appears to be clearly superior to the others.


Cryogenics ◽  
1997 ◽  
Vol 37 (1) ◽  
pp. 1-9 ◽  
Author(s):  
T. Kitamura ◽  
K. Shiramizu ◽  
N. Fujimoto ◽  
Y.F. Rao ◽  
K. Fukuda

Author(s):  
Mauricio A. Sa´nchez ◽  
William H. Sutton ◽  
Carlos A. Sa´nchez

Nonbearing walls made of concrete frequently include one or two-dimensional gaps between sections to allow the concrete exert expansion or contraction due to temperature transients. These section gaps require the use of a thermal fire barrier to stop a fire from spreading during a period of time. In some applications, such as seismic structures, fire barriers are large and form substructures and partial enclosures. These type of fire barriers are often manufactured by layering alternating blankets of ceramic fiber insulation with bounding thin metallic foil sheets. In this case, the barrier must meet the specifications and effectiveness given by the ASTM standard E-119. This effectiveness is determined by the requirement of maintaining structural integrity by allowing some heat release while not permitting the fire flame to pass through. Little data is available on the thermal interaction of 2-D corners and splicing the layers for large barriers. It is expected that spatial and angular effects might either degrade performance or even cause “hot spots” in a barrier wall. Therefore, a numerical simulation of the barrier is accomplished by utilizing the spectral/gray and directional/modeled data of each one of the components and by taking into account two common geometrical building shapes. This simulation analysis is done by coupling of the discrete ordinates method in radiation heat transfer and the energy equation to previously published thermophysical experimental data used as a validation of the properties for fire barrier materials. Some of the effects of directional and surface properties and radiative heat transfer in fire barrier materials have been included in the numerical model. The Fluent®-based numerical model is able to match thermal performance of previous test systems. Initial calculations suggest that a fire barrier consisting of a 2D corner geometry exposed to a fire from either side would be thermally less robust than a slab of the same characteristic aspect ratio. This approximation has shown a preferential orientation for the barrier to be positioned when a fire or other high energy source is postulated.


Author(s):  
Anil Yuksel ◽  
Edward T. Yu ◽  
Michael Cullinan ◽  
Jayathi Murthy

The temperature evolution of nanoparticle packings on a substrate under high laser power is investigated both experimentally and via numerical simulations. Numerical modeling of temperature distributions in copper nanoparticle packings on a glass substrate is performed and results are compared with experiment under 2.6 kW/cm2 laser power. A coupled electromagnetic-heat transfer model is implemented to understand the nanoparticle temperature distribution. Very good agreement between the coupled electromagnetic-heat transfer model and the experimental results is obtained by matching the interfacial thermal conductance, G, between the nanoparticles using the experimental result in the coupled electromagnetic-heat transfer model.


2019 ◽  
Vol 128 ◽  
pp. 07001
Author(s):  
Georges El Achkar ◽  
Bin Liu ◽  
Rachid Bennacer

In this paper, the thermohydraulic performance of a reciprocating room temperature active magnetic regenerator (AMR), with gadolinium (Gd) particles used as a magnetocaloric material (MCM) and water used as a working fluid, was numerically investigated. A two-dimensional transient flow model was developed using COMSOL Multiphysics, in order to determine the water flow distribution in two AMRs of cross and parallel Gd particles distributions for different water inlet velocities of 0.06 m.s-1, 0.08 m.s-1 , 0.1 m.s-1 and 0.12 m.s-1. The Gd particles have a radius of 1.5 mm and a distance from one another of 0.9 mm. Based on the simulations results of the first model, a two-dimensional transient coupled flow and heat transfer model was then developed using COMSOL Multiphysics, in order to characterise the convective heat transfer in the AMR of cross Gd particles distribution for the same water inlet velocities.


2011 ◽  
Vol 179-180 ◽  
pp. 239-242
Author(s):  
Hai Chuan Tian ◽  
Feng Xu ◽  
Guo Li Yang ◽  
Teng Fei Wu

The two-dimensional unsteady heat transfer model is been established. Analyzing on heat storage-release property of phase change thermal storage device within the fluid parallel spiral pipes in various conditions, suggestions are put forward to strengthen thermal storage for the device.


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