The paper considers the causes of increased vibration of four auxiliary diesel-generator sets of "Sulzer" 5АL25 type on board nine refrigerated vessels of B437 / 11 project after 15 years of operation. The proposed wide range of possible applications to address the problem of high vibration of diesel generators and motor vessels there were generally implemented upgraded turbocharger brackets, engine sub-frame and supporting spiral-rope vibration isolators in the shock absorption system of the diesel-generator. Four original patented technical solutions have been presented, among which one solution is implemented in 5AL25 diesel generator and 2H 8.5/11 diesel damping systems. There has been offered wide application both wire rope vibration isolators and combined isolators, in which elastic elements are made of nonflammable materials. Wire rope vibration isolators combine high bearing capacity (static loads within 1 N - 50 kN) with high elasticity under dynamic effects; their natural frequencies can drop to 2.5 Hz. Under the worst conditions 75% of the free moving weakens the impact to values that ensure the necessary safety of the object. Experience in designing vibration isolation systems allows to set the maximum range of loads within 15 - 25 g. The vibration isolators made of steel wire rope are practically not affected by the environment, they are made of stainless steel. They effectively operate at temperatures -200°C - +370°C in the presence of oil, dirt, sand, salt fog, etc. They usually have a service life comparable with the service life of the insulated object. Wire rope vibration isolators and combined vibration isolators can be used in all fields of modern technology: shipbuilding, power engineering, automotive, aviation and space industries, etc.