3D Stochastic Modeling of Columnar-to-Equiaxed Transition During the Solidification of Alloy 718

2014 ◽  
Author(s):  
Laurentiu Nastac ◽  
Daojie Zhang
Keyword(s):  
Stochastic Modeling ◽  
3D Model ◽  
Three Dimensional ◽  
Alloy 718 ◽  
Solute Redistribution ◽  
Cpu Time ◽  
Growth Anisotropy ◽  
Columnar To Equiaxed Transition ◽  
2D And 3D ◽  
Liquid And Solid Phases

An efficient three-dimensional (3D) stochastic model for simulating the evolution of dendritic crystals during the solidification of alloys was developed. The model includes time-dependent computations for temperature distribution, solute redistribution in the liquid and solid phases, curvature, and growth anisotropy. The 3D model can run on PCs with reasonable amount of RAM and CPU time and therefore no parallel computations are needed. 3D mesoscopic computations at the dendrite tip length scale were performed in this study to simulate the formation of the columnar-to-equiaxed transition in alloy 718. Comparisons between microstructure predictions obtained via 2D and 3D stochastic modeling are also presented.

Segregation Patterns and the Phase-Field 3D-Model for Adiabatic Phase Transition in Al-Cu Alloys

2013 ◽  
Vol 668 ◽  
pp. 870-874
Author(s):  
Heng Min Ding ◽  
Tie Qiao Zhang ◽  
Lv Chun Pu
Keyword(s):  
Dendritic Growth ◽  
3D Model ◽  
Three Dimensional ◽  
Cartesian Grid ◽  
Solute Diffusion ◽  
Solute Redistribution ◽  
Cu Alloys ◽  
Solid Phases ◽  
Solid Liquid ◽  
Liquid And Solid Phases

In the paper, a model basing on solute conservative in every unit is developed for solving the solute diffusion equation during solidification. The model includes time-dependent calculations for temperature distribution, solute redistribution in the liquid and solid phases. Three-dimensional computations are performed for Al-Cu dendritic growth into an adiabatic and highly supersaturated liquid phase. A numerical algorithm was developed to explicitly track the sharp solid/liquid (S/L) interface on a fixed Cartesian grid. Three-dimensional mesoscopic calculations were performed to simulate the evolution of equiaxed dendritic morphologies.

Regimes of Dry Convection above Wildfires: Sensitivity to Fire Line Details

2010 ◽  
Vol 67 (3) ◽  
pp. 611-632 ◽  
Author(s):  
Michael T. Kiefer ◽  
Matthew D. Parker ◽  
Joseph J. Charney
Keyword(s):  
Line Shape ◽  
3D Model ◽  
Three Dimensional ◽  
Vertical Wind Shear ◽  
Heating Rates ◽  
3D Simulations ◽  
Complex Phenomena ◽  
2D And 3D ◽  
The Impact ◽  
Dry Convection

Abstract Fire lines are complex phenomena with a broad range of scales of cross-line dimension, undulations, and along-line variation in heating rates. While some earlier studies have examined parcel processes in two-dimensional simulations, the complexity of fire lines in nature motivates a study in which the impact of three-dimensional fire line details on parcel processes is examined systematically. This numerical modeling study aims to understand how fundamental processes identified in 2D simulations operate in 3D simulations where the fire line is neither straight nor uniform in intensity. The first step is to perform simulations in a 3D model, with no fire line undulations or inhomogeneity. In general, convective modes simulated in the 2D model are reproduced in the 3D model. In one particular case with strong vertical wind shear, new convection develops separate from the main line of convection as a result of local changes to parcel speed and heating. However, in general the processes in the 2D and 3D simulations are identical. The second step is to examine 3D experiments wherein fire line shape and along-line inhomogeneity are varied. Parcel heating, as well as convective mode, is shown to exhibit sensitivity to fire line shape and along-line inhomogeneity.

Three-Dimensional Modeling of Container Cranes

2013 ◽  
Author(s):  
Andrea Arena ◽  
Arnaldo Casalotti ◽  
Walter Lacarbonara ◽  
Matthew P. Cartmell
Keyword(s):  
3D Modeling ◽  
3D Model ◽  
Initial Conditions ◽  
Three Dimensional ◽  
Container Cranes ◽  
Three Dimensional Modeling ◽  
Dimensional Modeling ◽  
Time Marching ◽  
Constrained Model ◽  
2D And 3D

This work deals with three-dimensional (3D) modeling of container cranes including the hoisting cable length commands. The proposed models allow to effectively study the 3D motion caused by the eccentricity of initial conditions or loading conditions such as those induced by wind. The container is modeled as a 3D rigid body while the hoisting cables are treated either as inextensible trusses or as linearly elastic straight, taut cables. The 3D model with inextensible cables is shown to coalesce into existing two-dimensional models under the relevant planarity constraints. Details about the treatment of the internal inextensibility constraints are discussed. Time-marching simulations are carried out to show representative 2D and 3D responses to initial conditions and commanded motion of the trolley. The main differences between the constrained model and that with the elasticity of the cables are highlighted in the framework of a few significant design scenarios.

scholarly journals Homogeneous 2D and 3D alignment of cardiomyocyte in dilated cardiomyopathy revealed by intravital heart imaging

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kiyoshi Masuyama ◽  
Tomoaki Higo ◽  
Jong-Kook Lee ◽  
Ryohei Matsuura ◽  
Ian Jones ◽  
...  
Keyword(s):  
Heart Failure ◽  
Dilated Cardiomyopathy ◽  
Cardiac Dysfunction ◽  
Three Dimensional ◽  
Single Layer ◽  
Specific Pattern ◽  
Two Dimensional ◽  
Heart Imaging ◽  
Novel Method ◽  
2D And 3D

AbstractIn contrast to hypertrophic cardiomyopathy, there has been reported no specific pattern of cardiomyocyte array in dilated cardiomyopathy (DCM), partially because lack of alignment assessment in a three-dimensional (3D) manner. Here we have established a novel method to evaluate cardiomyocyte alignment in 3D using intravital heart imaging and demonstrated homogeneous alignment in DCM mice. Whilst cardiomyocytes of control mice changed their alignment by every layer in 3D and position twistedly even in a single layer, termed myocyte twist, cardiomyocytes of DCM mice aligned homogeneously both in two-dimensional (2D) and in 3D and lost myocyte twist. Manipulation of cultured cardiomyocyte toward homogeneously aligned increased their contractility, suggesting that homogeneous alignment in DCM mice is due to a sort of alignment remodelling as a way to compensate cardiac dysfunction. Our findings provide the first intravital evidence of cardiomyocyte alignment and will bring new insights into understanding the mechanism of heart failure.

scholarly journals Do 3D Face Images Capture Cues of Strength, Weight, and Height Better than 2D Face Images do?

2021 ◽  
Vol 7 (3) ◽  
pp. 209-219
Author(s):  
Iris J Holzleitner ◽  
Alex L Jones ◽  
Kieran J O’Shea ◽  
Rachel Cassar ◽  
Vanessa Fasolt ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Physical Characteristics ◽  
Two Dimensional ◽  
3D Images ◽  
3D Face ◽  
Face Images ◽  
Similar Accuracy ◽  
2D And 3D ◽  
2D Images ◽  
Better Than

Abstract Objectives A large literature exists investigating the extent to which physical characteristics (e.g., strength, weight, and height) can be accurately assessed from face images. While most of these studies have employed two-dimensional (2D) face images as stimuli, some recent studies have used three-dimensional (3D) face images because they may contain cues not visible in 2D face images. As equipment required for 3D face images is considerably more expensive than that required for 2D face images, we here investigated how perceptual ratings of physical characteristics from 2D and 3D face images compare. Methods We tested whether 3D face images capture cues of strength, weight, and height better than 2D face images do by directly comparing the accuracy of strength, weight, and height ratings of 182 2D and 3D face images taken simultaneously. Strength, height and weight were rated by 66, 59 and 52 raters respectively, who viewed both 2D and 3D images. Results In line with previous studies, we found that weight and height can be judged somewhat accurately from faces; contrary to previous research, we found that people were relatively inaccurate at assessing strength. We found no evidence that physical characteristics could be judged more accurately from 3D than 2D images. Conclusion Our results suggest physical characteristics are perceived with similar accuracy from 2D and 3D face images. They also suggest that the substantial costs associated with collecting 3D face scans may not be justified for research on the accuracy of facial judgments of physical characteristics.

scholarly journals Direct 3D model extraction method for color volume images

2021 ◽  
Vol 29 ◽  
pp. 133-140
Author(s):  
Bin Liu ◽  
Shujun Liu ◽  
Guanning Shang ◽  
Yanjie Chen ◽  
Qifeng Wang ◽  
...  
Keyword(s):  
3D Model ◽  
Clinical Medicine ◽  
Three Dimensional ◽  
Laplacian Matrix ◽  
Segmentation Method ◽  
Human Organs ◽  
Model Segmentation ◽  
Treatment Objective ◽  
Organ Models ◽  
Different Parts

BACKGROUND: There is a great demand for the extraction of organ models from three-dimensional (3D) medical images in clinical medicine diagnosis and treatment. OBJECTIVE: We aimed to aid doctors in seeing the real shape of human organs more clearly and vividly. METHODS: The method uses the minimum eigenvectors of Laplacian matrix to automatically calculate a group of basic matting components that can properly define the volume image. These matting components can then be used to build foreground images with the help of a few user marks. RESULTS: We propose a direct 3D model segmentation method for volume images. This is a process of extracting foreground objects from volume images and estimating the opacity of the voxels covered by the objects. CONCLUSIONS: The results of segmentation experiments on different parts of human body prove the applicability of this method.

Extracellular vesicles from three dimensional culture of human placental mesenchymal stem cells ameliorated renal ischemia/reperfusion injury

2021 ◽  
pp. 039139882098680
Author(s):  
Xuefeng Zhang ◽  
Nan Wang ◽  
Yuhua Huang ◽  
Yan Li ◽  
Gang Li ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Extracellular Vesicles ◽  
Therapeutic Potential ◽  
Expression Profiles ◽  
Ischemia Reperfusion ◽  
Three Dimensional ◽  
3D Culture ◽  
Placental Mesenchymal Stem Cells ◽  
2D And 3D

Background: Three-dimensional (3D) culture has been reported to increase the therapeutic potential of mesenchymal stem cells (MSCs). The present study assessed the therapeutic efficacy of extracellular vesicles (EVs) from 3D cultures of human placental MSCs (hPMSCs) for acute kidney injury (AKI). Methods: The supernatants from monolayer culture (2D) and 3D culture of hPMSCs were ultra-centrifuged for EVs isolation. C57BL/6 male mice were submitted to 45 min bilateral ischemia of kidney, followed by renal intra-capsular administration of EVs within a 72 h reperfusion period. Histological, immunohistochemical, and ELISA analyses of kidney samples were performed to evaluate cell death and inflammation. Kidney function was evaluated by measuring serum creatinine and urea nitrogen. The miRNA expression profiles of EVs from 2D and 3D culture of hPMSCs were evaluated using miRNA microarray analysis. Results: The 3D culture of hPMSCs formed spheroids with different diameters depending on the cell density seeded. The hPMSCs produced significantly more EVs in 3D culture than in 2D culture. More importantly, injection of EVs from 3D culture of hPMSCs into mouse kidney with ischemia-reperfusion (I/R)-AKI was more beneficial in protecting from progression of I/R than those from 2D culture. The EVs from 3D culture of hPMSCs were more efficient against apoptosis and inflammation than those from 2D culture, which resulted in a reduction in tissue damage and amelioration of renal function. MicroRNA profiling analysis revealed that a set of microRNAs were significantly changed in EVs from 3D culture of hPMSCs, especially miR-93-5p. Conclusion: The EVs from 3D culture of hPMSCs have therapeutic potential for I/R-AKI.

scholarly journals Value of Three-Dimensional Digital Subtraction Angiography for Detection and Classification of Intracranial Aneurysm Remnants After Clipping

2021 ◽  
Author(s):  
Serge Marbacher ◽  
Matthias Halter ◽  
Deborah R Vogt ◽  
Jenny C Kienzler ◽  
Christian T J Magyar ◽  
...  
Keyword(s):  
Intracranial Aneurysm ◽  
Digital Subtraction Angiography ◽  
Diagnostic Yield ◽  
Three Dimensional ◽  
P Value ◽  
Digital Subtraction ◽  
Patient Demographics ◽  
Included Patient ◽  
2D And 3D

Abstract BACKGROUND The current gold standard for evaluation of the surgical result after intracranial aneurysm (IA) clipping is two-dimensional (2D) digital subtraction angiography (DSA). While there is growing evidence that postoperative 3D-DSA is superior to 2D-DSA, there is a lack of data on intraoperative comparison. OBJECTIVE To compare the diagnostic yield of detection of IA remnants in intra- and postoperative 3D-DSA, categorize the remnants based on 3D-DSA findings, and examine associations between missed 2D-DSA remnants and IA characteristics. METHODS We evaluated 232 clipped IAs that were examined with intraoperative or postoperative 3D-DSA. Variables analyzed included patient demographics, IA and remnant distinguishing characteristics, and 2D- and 3D-DSA findings. Maximal IA remnant size detected by 3D-DSA was measured using a 3-point scale of 2-mm increments. RESULTS Although 3D-DSA detected all clipped IA remnants, 2D-DSA missed 30.4% (7 of 23) and 38.9% (14 of 36) clipped IA remnants in intraoperative and postoperative imaging, respectively (95% CI: 30 [ 12, 49] %; P-value .023 and 39 [23, 55] %; P-value = <.001), and more often missed grade 1 (< 2 mm) clipped remnants (odds ratio [95% CI]: 4.3 [1.6, 12.7], P-value .005). CONCLUSION Compared with 2D-DSA, 3D-DSA achieves a better diagnostic yield in the evaluation of clipped IA. Our proposed method to grade 3D-DSA remnants proved to be simple and practical. Especially small IA remnants have a high risk to be missed in 2D-DSA. We advocate routine use of either intraoperative or postoperative 3D-DSA as a baseline for lifelong follow-up of clipped IA.

Two-dimensional-Wilkins and real-time transesophageal three-dimensional scoring systems: Which one is preferred to mitral valve morphological assessment?

2021 ◽  
pp. 021849232110304
Author(s):  
Mehrnoush Toufan ◽  
Zahra Jabbary ◽  
Naser Khezerlou aghdam
Keyword(s):  
Mitral Valve ◽  
Transthoracic Echocardiography ◽  
Scoring System ◽  
Three Dimensional ◽  
Scoring Systems ◽  
Two Dimensional ◽  
Mitral Valve Area ◽  
2D And 3D ◽  
Morphological Assessment ◽  
Valve Area

Background To quantify valvular morphological assessment, some two-dimensional (2D) and three-dimensional (3D) scoring systems have been developed to target the patients for balloon mitral valvuloplasty; however, each scoring system has some potential limitations. To achieve the best scoring system with the most features and the least restrictions, it is necessary to check the degree of overlap of these systems. Also the factors related to the accuracy of these systems should be studied. We aimed to determine the correlation between the 2D Wilkins and real-time transesophageal three-dimensional (RT3D-TEE) scoring systems. Methods This cross-sectional study was performed on 156 patients with moderate to severe mitral stenosis who were candidates for percutaneous balloon valvuloplasty. To morphologic assessment of mitral valve, patients were examined by 2D-transthoracic echocardiography and RT3D-TEE techniques on the same day. Results A strong association was found between total Wilkins and total RT3D-TEE scores (r = 0.809, p < 0.001). The mean mitral valve area assessed by the 2D and 3D was 1.07 ± 0.25 and 1.03 ± 0.26, respectively, indicating a mean difference of 0.037 cm2 (p = 0.001). We found a strong correlation between the values of mitral valve area assessed by 2D and 3D techniques (r = 0.846, p < 0.001). Conclusion There is a high correlation between the two scoring systems in terms of evaluating dominant morphological features. Partially, mitral valve area overestimation in the 2D-transthoracic echocardiography and its inability to assess commissural involvement as well as its dependence on patient age were exceptions in this study.

scholarly journals Extending In-Plane Impedance Measurements from 2D to 3D Cultures: Design Considerations

2021 ◽  
Vol 8 (1) ◽  
pp. 11
Author(s):  
Sorel E. De Leon ◽  
Lana Cleuren ◽  
Zay Yar Oo ◽  
Paul R. Stoddart ◽  
Sally L. McArthur
Keyword(s):  
Three Dimensional ◽  
3D Culture ◽  
Collagen Gel ◽  
Impedance Measurement ◽  
Impedance Spectrum ◽  
3D Models ◽  
Low Frequencies ◽  
3D Cell Cultures ◽  
3D Collagen ◽  
2D And 3D

Three-dimensional (3D) cell cultures have recently emerged as tools for biologically modelling the human body. As 3D models make their way into laboratories there is a need to develop characterisation techniques that are sensitive enough to monitor the cells in real time and without the need for chemical labels. Impedance spectroscopy has been shown to address both of these challenges, but there has been little research into the full impedance spectrum and how the different components of the system affect the impedance signal. Here we investigate the impedance of human fibroblast cells in 2D and 3D collagen gel cultures across a broad range of frequencies (10 Hz to 5 MHz) using a commercial well with in-plane electrodes. At low frequencies in both 2D and 3D models it was observed that protein adsorption influences the magnitude of the impedance for the cell-free samples. This effect was eliminated once cells were introduced to the systems. Cell proliferation could be monitored in 2D at intermediate frequencies (30 kHz). However, the in-plane electrodes were unable to detect any changes in the impedance at any frequency when the cells were cultured in the 3D collagen gel. The results suggest that in designing impedance measurement devices, both the nature and distribution of the cells within the 3D culture as well as the architecture of the electrodes are key variables.

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