Medical X-Ray Imaging The Evolving State Of The Art

1974 ◽  
Author(s):  
Stanley S. Grossel
Keyword(s):  
X Ray ◽  
2016 ◽  
Vol 34 (4) ◽  
pp. 637-644 ◽  
Author(s):  
I.A. Artyukov ◽  
E.G. Bessonov ◽  
M.V. Gorbunkov ◽  
Y.Y. Maslova ◽  
N.L. Popov ◽  
...  

AbstractThe paper presents a general theoretical framework and related Monte Carlo simulation of novel type of the X-ray sources based on relativistic Thomson scattering of powerful laser radiation. Special attention is paid to the linac X-ray generators by way of two examples: conceptual design for production of 12.4 keV photons and presently operating X-ray source of 29.4 keV photons. Our analysis shows that state-of-the-art laser and accelerator technologies enable to build up a compact linac-based Thomson source for the same X-ray imaging and diffraction experiments as in using of a large-scale X-ray radiation facility like a synchrotron or Thomson generator based on electron storage ring.


Author(s):  
Prof. Dr. Rajalakshmi M C ◽  
Bhuvana Sahi M ◽  
Bindu P ◽  
Pavan Kumar N ◽  
Pramod Athrey A

In this study, a dataset of X-ray images from patients with confirmed Covid -19 disease, and normal incidents, was utilized for the automatic detection of the Coronavirus disease. The aim of the study is to evaluate the performance of state-of-the-art convolutional neural network architectures proposed over the recent years for medical image classification. Specifically, the procedure called Transfer Learning was adopted. With transfer learning, the detection of various abnormalities in small medical image datasets is an achievable target, often yielding remarkable results. The datasets utilized in this experiment are Firstly, a collection of 5222 X-ray images including 3875 images with confirmed Covid -19 disease and 1347 images of normal conditions. The data was collected from the available X-ray images on public medical repositories. The results suggest that Deep Learning with X-ray imaging may extract significant biomarkers related to the Covid -19 disease, while the best accuracy, sensitivity, and specificity obtained is 96.78%, 98.66%, and 96.46% respectively. Since by now, all diagnostic tests show failure rates such as to raise concerns, the probability of incorporating X -rays into the diagnosis of the disease could be assessed by the medical community, based on the findings, while more research to evaluate the X-ray approach from different aspects may be conducted.


2018 ◽  
Vol 03 (03n04) ◽  
pp. 1841002 ◽  
Author(s):  
Sabine Thürauf ◽  
Oliver Hornung ◽  
Mario Körner ◽  
Florian Vogt ◽  
Alois Knoll ◽  
...  

In interventional radiology or surgery, C-arm systems are typical imaging modalities. Apart from 2D X-ray images, C-arm systems are able to perform 2D/3D overlays. For this application, a previously recorded 3D volume is projected on a 2D X-ray image for providing additional information to the clinician. The required accuracy for this application is 1.5[Formula: see text]mm. Such a spatial accuracy is only achievable with C-arms, if a calibration is performed. State-of-the-art approaches interpolate between values of lookup tables of a sampled Cartesian volume. However, due to the non-linear system behavior in Cartesian space, a trade-off between the calibration effort and the calibrated volume is necessary. This leads to the calibration of the most relevant subvolume and high calibration times. We discuss a new model-based calibration approach for C-arm systems which potentially leads to a smaller calibration effort and simultaneously to an increased calibrated volume. In this work, we demonstrate that it is possible to calibrate a robotic C-arm system using X-ray images and that a static model of the system is required to achieve the desired accuracy for 2D/3D overlays, if re-orientations of the system are performed.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Amlan Datta ◽  
John Fiala ◽  
Shariar Motakef

AbstractX-ray radiography is the most widely used imaging technique with applications encompassing medical and industrial imaging, homeland security, and materials research. Although a significant amount of research and development has gone into improving the spatial resolution of the current state-of-the-art indirect X-ray detectors, it is still limited by the detector thickness and microcolumnar structure quality. This paper demonstrates high spatial resolution X-ray imaging with solution-processable two-dimensional hybrid perovskite single-crystal scintillators grown inside microcapillary channels as small as 20 µm. These highly scalable non-hygroscopic detectors demonstrate excellent spatial resolution similar to the direct X-ray detectors. X-ray imaging results of a camera constructed using this scintillator show Modulation Transfer Function values significantly better than the current state-of-the-art X-ray detectors. These structured detectors open up a new era of low-cost large-area ultrahigh spatial resolution high frame rate X-ray imaging with numerous applications.


Author(s):  
M.G. Baldini ◽  
S. Morinaga ◽  
D. Minasian ◽  
R. Feder ◽  
D. Sayre ◽  
...  

Contact X-ray imaging is presently developing as an important imaging technique in cell biology. Our recent studies on human platelets have demonstrated that the cytoskeleton of these cells contains photondense structures which can preferentially be imaged by soft X-ray imaging. Our present research has dealt with platelet activation, i.e., the complex phenomena which precede platelet appregation and are associated with profound changes in platelet cytoskeleton. Human platelets suspended in plasma were used. Whole cell mounts were fixed and dehydrated, then exposed to a stationary source of soft X-rays as previously described. Developed replicas and respective grids were studied by scanning electron microscopy (SEM).


Author(s):  
James F. Mancuso ◽  
William B. Maxwell ◽  
Russell E. Camp ◽  
Mark H. Ellisman

The imaging requirements for 1000 line CCD camera systems include resolution, sensitivity, and field of view. In electronic camera systems these characteristics are determined primarily by the performance of the electro-optic interface. This component converts the electron image into a light image which is ultimately received by a camera sensor.Light production in the interface occurs when high energy electrons strike a phosphor or scintillator. Resolution is limited by electron scattering and absorption. For a constant resolution, more energy deposition occurs in denser phosphors (Figure 1). In this respect, high density x-ray phosphors such as Gd2O2S are better than ZnS based cathode ray tube phosphors. Scintillating fiber optics can be used instead of a discrete phosphor layer. The resolution of scintillating fiber optics that are used in x-ray imaging exceed 20 1p/mm and can be made very large. An example of a digital TEM image using a scintillating fiber optic plate is shown in Figure 2.


Author(s):  
Ann LeFurgey ◽  
Peter Ingram ◽  
J.J. Blum ◽  
M.C. Carney ◽  
L.A. Hawkey ◽  
...  

Subcellular compartments commonly identified and analyzed by high resolution electron probe x-ray microanalysis (EPXMA) include mitochondria, cytoplasm and endoplasmic or sarcoplasmic reticulum. These organelles and cell regions are of primary importance in regulation of cell ionic homeostasis. Correlative structural-functional studies, based on the static probe method of EPXMA combined with biochemical and electrophysiological techniques, have focused on the role of these organelles, for example, in maintaining cell calcium homeostasis or in control of excitation-contraction coupling. New methods of real time quantitative x-ray imaging permit simultaneous examination of multiple cell compartments, especially those areas for which both membrane transport properties and element content are less well defined, e.g. nuclei including euchromatin and heterochromatin, lysosomes, mucous granules, storage vacuoles, microvilli. Investigations currently in progress have examined the role of Zn-containing polyphosphate vacuoles in the metabolism of Leishmania major, the distribution of Na, K, S and other elements during anoxia in kidney cell nuclel and lysosomes; the content and distribution of S and Ca in mucous granules of cystic fibrosis (CF) nasal epithelia; the uptake of cationic probes by mltochondria in cultured heart ceils; and the junctional sarcoplasmic retlculum (JSR) in frog skeletal muscle.


2000 ◽  
Vol 10 (PR9) ◽  
pp. Pr9-583-Pr9-588 ◽  
Author(s):  
W. A. Gooch ◽  
M. S. Burkins ◽  
G. Hauver ◽  
P. Netherwood ◽  
R. Benck
Keyword(s):  
X Ray ◽  

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