SU-E-I-68: The Relationship Between White Matter Tract Abnormalities and Brain Atrophy Correlation Analysis in Neurodegenerative Disease

2015 ◽  
Vol 42 (6Part6) ◽  
pp. 3257-3257
Author(s):  
R Juh ◽  
T Suh
2017 ◽  
Vol 1 (1) ◽  
pp. 01-02
Author(s):  
Melina Oison

Abnormalities of water homeostasis can be early expressions of neuronal dysfunction, brain atrophy, chronic cerebrovasculopathy and neurodegenerative disease. The aim of this study was to analyze the serum osmolality of subjects with cognitive impairment.The hydromolecular hypothesis intends to explain the relationship between dehydration and cognitive impairment in older patients as the result of protein misfolding and aggregation, in the presence of a low interstitial fluid volume, which is a defect of the microcirculation. Defective proteins were shown to impair the amount of information in brain biomolecular mechanisms, with consequent neuronal and synaptic damage.


2020 ◽  
Vol 17 (2) ◽  
pp. 96-105
Author(s):  
ZhiLi Niu ◽  
PingAn Zhang ◽  
Dong Li ◽  
ChengLiang Zhu ◽  
LiNa Feng ◽  
...  

Objective Apolipoprotein E (ApoE) is mainly synthesized in the liver. So far, it is unknown the relationship among <i>APOE</i> gene polymorphisms and WML, brain atrophy. Therefore, the aim of the study was to assess the associations of <i>APOE</i> gene polymorphisms in patients with WML and brain atrophy.Methods A total of 58 patients with WML, 128 patients with brain atrophy, 112 patients with co-occurrence of WML and brain atrophy and 95 healthy elderly volunteers were recruited from Renmin Hospital of WuHan University.Results Allele <i>E3</i> was the most common allele. The alleles <i>E2</i> had significantly higher levels of ApoB and lower age in WML group. The alleles <i>E2</i> was associated with the lower level of ApoB, LDL-Ch, TCh, and sdLDL in co-occurrence group. The <i>E3</i>/<i>E3</i> genotype has higher level of sdLDL, but lower age and female frequency in WML. The <i>E3</i>/E4 genotype had higher level of TG, but lower age in WML. Gender, Age, <i>E2</i>, Hyperhomocysteinemia and UA were also significantly associated with disease progression.Conclusion This study found that clinical data, lipids and metabolic complications were closely related to ApoE genotypes and alleles, and also disease progression and type.


1985 ◽  
Vol 24 (02) ◽  
pp. 91-100 ◽  
Author(s):  
W. van Pelt ◽  
Ph. H. Quanjer ◽  
M. E. Wise ◽  
E. van der Burg ◽  
R. van der Lende

SummaryAs part of a population study on chronic lung disease in the Netherlands, an investigation is made of the relationship of both age and sex with indices describing the maximum expiratory flow-volume (MEFV) curve. To determine the relationship, non-linear canonical correlation was used as realized in the computer program CANALS, a combination of ordinary canonical correlation analysis (CCA) and non-linear transformations of the variables. This method enhances the generality of the relationship to be found and has the advantage of showing the relative importance of categories or ranges within a variable with respect to that relationship. The above is exemplified by describing the relationship of age and sex with variables concerning respiratory symptoms and smoking habits. The analysis of age and sex with MEFV curve indices shows that non-linear canonical correlation analysis is an efficient tool in analysing size and shape of the MEFV curve and can be used to derive parameters concerning the whole curve.


2020 ◽  
Author(s):  
endang naryono

This study examines the influence of receivables on liquidity at PT. Graha Tumarima. Sukabumi City for 5 years, with a sampling technique using a purposive sample in the form of financial statement data from 2010 to 2014 using a table of trade receivables and company liquidity. In this study, researchers refer to the theory of Bambang Riyanto (2008: 94) as the connecting theory of the title. This study aims to determine whether there is a relationship and influence between receivables and liquidity at PT. Graha Tumarima. The research design uses the method of exposing the facto, the method of data collection aims to test the hypothesis by using correlation analysis, determination, regression and hypothesis testing with t-test. The results of this study show the influence of receivables on liquidity is shown by the value of r = 0.888, meaning that receivables have a very strong relationship to liquidity. The nature of the relationship is positive, meaning that if the value of cooperative credit is higher the liquidity will be higher. Conversely, if the value of receivables decreases, liquidity will decrease. The magnitude of the influence of receivables on liquidity is shown by the value of R Square / Determination Coefficient of 0.789 or 78.9% thus the receivables have an effect of 78.9% on cooperative liquidity. Hypothesis testing uses the t test, that t arithmetic = 3.347 while t table = 3.182 means t arithmetic&gt; t table. Means that Ho is rejected and Ha is accepted. There is an influence between the receivables on liquidity at PT. Graha Tumarima, Sukabumi City


2015 ◽  
Vol 10 (3) ◽  
pp. 155892501501000 ◽  
Author(s):  
Canan Saricam

This paper discusses the influence of the production parameters on the moisture related comfort characteristics of the compression garments that differ according to the tension applied during the production and elastane count. Correlation analysis, two sided independent t-test analysis and ANOVA tests were applied to analyze the relationship between the production parameters and comfort characteristics which are absorption, vertical and transfer wicking and drying. It was found that tension and elastane composition affect the comfort characteristics by changing the porosity, thickness and the pathways within the fabric.


Foods ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 86
Author(s):  
So-Ra Yoon ◽  
Yun-Mi Dang ◽  
Su-Yeon Kim ◽  
Su-Yeon You ◽  
Mina K. Kim ◽  
...  

Capsaicinoid content, among other factors, affects the perception of spiciness of commercial kimchi. Here, we investigated whether the physicochemical properties of kimchi affect the spicy taste of capsaicinoids perceived by the tasting. High-performance liquid chromatography (HPLC) was used to evaluate the capsaicinoid content (mg/kg) of thirteen types of commercial kimchi. The physicochemical properties such as pH, titratable acidity, salinity, free sugar content, and free amino acid content were evaluated, and the spicy strength grade was determined by selected panel to analyze the correlation between these properties. Panels were trained for 48 h prior to actual evaluation by panel leaders trained for over 1000 h according to the SpectrumTM method. Partial correlation analysis was performed to examine other candidate parameters that interfere with the sensory evaluation of spiciness and capsaicinoid content. To express the specific variance after eliminating the effects of other variables, partial correlations were used to estimate the relationships between two variables. We observed a strong correlation between spiciness intensity ratings and capsaicinoid content, with a Pearson’s correlation coefficient of 0.78 at p ≤ 0.001. However, other specific variables may have influenced the relationship between spiciness intensity and total capsaicinoid content. Partial correlation analysis indicated that the free sugar content most strongly affected the relationship between spiciness intensity and capsaicinoid content, showing the largest first-order partial correlation coefficient (rxy/z: 0.091, p ≤ 0.01).


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