Effect of Supplementation With Ecklonia cava Polyphenol on Endurance Performance of College Students

2010 ◽  
Vol 20 (1) ◽  
pp. 72-79 ◽  
Author(s):  
Jae-Keun Oh ◽  
Young-Oh Shin ◽  
Jin-Ho Yoon ◽  
Seong Ho Kim ◽  
Hyeon-Cheol Shin ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Radical Scavenging ◽  
Endurance Performance ◽  
Acute Effect ◽  
Ecklonia Cava ◽  
Time To Exhaustion ◽  
Endurance Capacity ◽  
Intense Exercise ◽  
The Difference ◽  
Lactate Levels

Ecklonia cava polyphenol (ECP) is a potent antioxidant and procirculatory agent that may contribute to improvement of endurance performance during highly intense exercise. This study evaluated the acute effect of an ECP-supplemented drink against a placebo on maximum endurance capacity and related physiological parameters. Twenty men 18–23 yr old volunteered as participants. Each performed 2 randomized trials with a 1-week interval between them. One trial was with ECP and the other with a placebo drink. Participants in this randomized, placebo-controlled, crossover design ingested either a placebo or ECP drink 30 min before each exercise trial. Time to exhaustion, VO2max, and postexercise blood glucose and lactate levels were evaluated. ECP supplementation increased time to exhaustion (2.39 min) compared with placebo. This result was accompanied by a 6.5% higher mean VO2max in the ECP group, although the difference was not statistically significant. The blood glucose level in the ECP group at 3 min after exhaustive exercise was significantly higher than that of the placebo group (+ 9.9%). The postexercise blood lactate levels in the ECP group showed a decreasing trend compared with placebo, but it was nonsignificant. This study was not able to determine any physiological mechanisms behind the improved endurance performance, but, based on these results, it is speculated that the ECP supplementation may have contributed to enhanced oxidation of glucose and less production of lactate during intense exercise, possibly by its free-radical-scavenging and procirculatory activities. However, careful verification is required to elucidate the correct mechanism.

Influence of Carbohydrate Ingestion on Blood Glucose and Performance in Runners

1992 ◽  
Vol 2 (4) ◽  
pp. 317-327 ◽  
Author(s):  
Randall L. Wilber ◽  
Robert J. Moffatt
Keyword(s):  
Blood Glucose ◽  
Glucose Concentration ◽  
Perceived Exertion ◽  
Treadmill Exercise ◽  
Blood Glucose Concentration ◽  
Endurance Performance ◽  
Time To Exhaustion ◽  
Experimental Conditions ◽  
Double Blind ◽  
Carbohydrate Ingestion

Ten trained male runners performed a treadmill exercise test at 80%under two experimental conditions, carbohydrate (CHO, 7% carbohydrate) and placebo (P), to determine the effect of carbohydrate ingestion on endurance performance (treadmill run time), blood glucose concentration, respiratory exchange ratio (RER), and subjective ratings of perceived exertion (RPE). Treatment order was randomized and counterbalanced and test solutions were administered double-blind. Ingestion took place 5 min preexercise (250 ml) and at 15-min intervals during exercise (125 ml). Performance was enhanced by 29.4% (p~ 0.05) during CHO (115 ±25 min) compared to P (92 ± 27 min). Blood glucose concentration was significantly greater during CHO (5.6 ± 0.9 mM) relative to P (5.0 ±0.7 mM). There was a significant increase in mean RER following CHO ingestion (.94±.01) compared to P (.90±.01). Average RPE was significantly less during CHO (14.5±2.3) relative to P (15.4±2.4). These data suggest that time to exhaustion of high-intensity treadmill exercise is delayed as a result of carbohydrate ingestion and that this effect is mediated by favorable alterations in blood glucose concentration and substrate utilization.

Bio-Koffein-Riegel vor dem Zeitfahren ­verbessern die Leistung und senken das ­Beanspruchungsempfinden

2015 ◽  
Vol 63 (1) ◽  
Keyword(s):  
Perceived Exertion ◽  
Endurance Performance ◽  
Underlying Mechanism ◽  
Time To Exhaustion ◽  
Incremental Test ◽  
Constant Intensity ◽  
Warm Up ◽  
Perception Of Effort ◽  
Lactate Levels ◽  
Single Blind

The intake of caffeine from tablets, coffee and energy drinks has shown to benefit endurance performance, whereas the effect of caffeine bars has not been investigated yet. Therefore, the aim of the study was to examine endurance performance, metabolism and perceived exertion following the co-ingestion of caffeine and carbohydrates in the form of bars. Using a randomized single-blind cross-over placebo-controlled design, nine male, trained cyclists completed endurance exercises on a cycling ergometer under the following conditions: ingestion of water (H2O), placebo bars (PLA) and caffeine bars (CAF; 5 mg caffeine/kg bodyweight), respectively, 45 min prior to the test. After 40 min at a constant intensity of 75% VO2max, which was assessed in a previously performed incremental test with spirometry, load was increased 10 W/min until exhaustion. In comparison to PLA and H2O, the intake of CAF resulted in a higher maximal power and longer time to exhaustion (p=0.002). Surprisingly, concentration of free fatty acids was lower at exhaustion (p=0.004), whereas blood lactate levels (p=0.021) and heart rate (p=0.008) were significantly higher after CAF. Furhermore, subjects reported lower received perception of effort at warm-up (0.034), 30 min (p=0.026) and 40 min (p=0.041) only when they ingested CAF previously. Caffeine bars have been proven as useful pre-exercise supplements, which induce temporary performance benefits. The underlying mechanism was a delayed perception of fatigue rather than an increased lipolysis.

scholarly journals Dose-dependent effect of capsaicin on endurance capacity in rats

2003 ◽  
Vol 90 (3) ◽  
pp. 515-520 ◽  
Author(s):  
Tae-Woong Oh ◽  
Fukio Ohta
Keyword(s):  
Body Weight ◽  
Muscle Glycogen ◽  
Endurance Performance ◽  
Swimming Exercise ◽  
Time To Exhaustion ◽  
Endurance Capacity ◽  
Maximal Effect ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Sparing Effect

The present study was designed to determine the effects of various levels of capsaicin (CAP) on endurance capacity in forty-nine male Sprague–Dawley rats, aged 4 weeks, which were assigned to four groups. Rats were given orally either control (0) or 6, 10 or 15 mg CAP/kg body weight 2 h before exercise by stomach intubations using a round-ended needle. The rats in each group were divided into two subgroups for resting or swimming exercise. Swimming exercise was performed with a weight corresponding to 3 % body weight attached to the tail, and endurance capacity was evaluated by swimming time to exhaustion. The highest dose (15 mg/kg) of CAP significantly (P < 0·05) increased endurance performance time and caused plasma non-esterified fatty acid to rise significantly by about 1·4-fold compared with that of non-CAP treated rats at exhaustion (P < 0·05). The highest dose of CAP had no effect on liver and gastrocnemius muscle glycogen (white and red) in resting rats, but significantly increased glycogen contents of both muscles at exhaustion (P < 0·05). At rest, plasma noradrenalin levels of the rats receiving the highest dose were greater than that of non-CAP-treated rats and remained greater until exhaustion. The effects of CAP on endurance capacity have received little attention and have conveyed conflicting impressions. Kim et al. (1997) failed to show the maximal effect of 10 mg/kg doses of CAP on swimming endurance time in mice. The influences of various doses of CAP on endurance capacity were still unclear. Matsuo et al. (1996) reported that the intake of CAP have little sparing effect on glycogen in the liver and soleus muscles at rest and during exercise in rats previously fed a CAP-containing diet ad libitum for 1 week. Our present results suggest more than the highest dose of CAP (15 mg/kg) can cause the increase of endurance capacity, which might be induced through the sparing of muscle glycogen and the rise of non-esterfied fatty acids following the increase of circulating catecholamine.

Effects of Coenzyme Athletic Performance System as an Ergogenic Aid on Endurance Performance to Exhaustion

1992 ◽  
Vol 2 (3) ◽  
pp. 272-286 ◽  
Author(s):  
Ian P. Snider ◽  
Terry L. Bazzarre ◽  
Scott D. Murdoch ◽  
Allan Goldfarb
Keyword(s):  
Blood Glucose ◽  
Athletic Performance ◽  
Performance Test ◽  
Endurance Performance ◽  
Crossover Design ◽  
Time To Exhaustion ◽  
Double Blind ◽  
Placebo Trial ◽  
Performance System ◽  
The Mean

This study examined the effects of the Coenzyme Athletic Performance System (CAPS) on endurance performance to exhaustion. CAPS contains 100 mg coenzyme Q10,500 mg cytochrome C, 100 mg inosine, and 200 IU vitamin E. Eleven highly trained male triathletes were given three daily doses of either CAPS or placebo (dicalcium phosphate) for two 4-week periods using a double-blind crossover design. A 4-week washout period separated the two treatment periods. An exhaustive performance test, consisting of 90 minutes of running on a treadmill (70%) followed by cycling (70%) until exhaustion, was conducted after each treatment period. The mean (±SEM) time to exhaustion for the subjects using CAPS (223 ±17 min) was not significantly different (p=0.57) from the placebo trial (215 ±9 min). Blood glucose, lactate, and free fatty acid concentrations at exhaustion did not differ between treatments (p< 0.05). CAPS had no apparent benefit on exercise to exhaustion.

Carbohydrate-Gel Supplementation and Endurance Performance during Intermittent High-Intensity Shuttle Running

2007 ◽  
Vol 17 (5) ◽  
pp. 445-455 ◽  
Author(s):  
Stephen D. Patterson ◽  
Susan C. Gray
Keyword(s):  
Blood Glucose ◽  
High Intensity ◽  
Endurance Performance ◽  
Soccer Players ◽  
Time To Exhaustion ◽  
Variable Speed ◽  
Healthy Male ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Male Subjects

The aim of this study was to investigate the effects of a carbohydrate (CHO) gel on performance after prolonged intermittent high-intensity shuttle running. Seven male soccer players performed 2 exercise trials, 7 d apart. On each occasion, participants completed five 15-min periods of intermittent variable-speed running, interspersed with periods of walking (Part A), followed by an intermittent run to exhaustion (Part B). Participants consumed either a CHO gel or placebo (PLA) immediately before exercise (0.89 mL/kg body mass [BM]) and every 15 min thereafter (0.35 mL/kg BM). In addition, water was consumed at a rate of 5 mL/kg BM before and 2 mL/kg BM every 15 min during exercise. Blood glucose levels were higher (P < 0.05) at 15, 30, and 60 min of exercise and at exhaustion in CHO than in PLA. During Part B, run time to exhaustion was longer (P < 0.05) in the CHO trial (CHO 6.1 ± 1.3 min vs. PLA 4.2 ± 1.2 min). These results indicate that ingesting a CHO gel, along with water, improves performance after prolonged intermittent running in healthy male subjects, possibly by maintaining blood glucose levels during exercise.

Attenuated hepatosplanchnic uptake of lactate during intense exercise in humans

2002 ◽  
Vol 92 (4) ◽  
pp. 1677-1683 ◽  
Author(s):  
H. B. Nielsen ◽  
J. O. Clemmesen ◽  
C. Skak ◽  
P. Ott ◽  
N. H. Secher
Keyword(s):  
Blood Flow ◽  
Blood Glucose ◽  
Blood Lactate ◽  
Venous Blood ◽  
Average Concentration ◽  
Intense Exercise ◽  
Indocyanine Green Dye ◽  
Arterial Blood ◽  
Hepatic Venous Blood ◽  
The Difference

We evaluated whether the increase in blood lactate with intense exercise is influenced by a low hepatosplanchnic blood flow as assessed by indocyanine green dye elimination and blood sampling from an artery and the hepatic vein in eight men. The hepatosplanchnic blood flow decreased from a resting value of 1.6 ± 0.1 to 0.7 ± 0.1 (SE) l/min during exercise. Yet the hepatosplanchnic O2uptake increased from 67 ± 3 to 93 ± 13 ml/min, and the output of glucose increased from 1.1 ± 0.1 to 2.1 ± 0.3 mmol/min ( P < 0.05). Even at the lowest hepatosplanchnic venous hemoglobin O2 saturation during exercise of 6%, the average concentration of glucose in arterial blood was maintained close to the resting level (5.2 ± 0.2 vs. 5.5 ± 0.2 mmol/l), whereas the difference between arterial and hepatic venous blood glucose increased to a maximum of 22 mmol/l. In arterial blood, the concentration of lactate increased from 1.1 ± 0.2 to 6.0 ± 1.0 mmol/l, and the hepatosplanchnic uptake of lactate was elevated from 0.4 ± 0.06 to 1.0 ± 0.05 mmol/min during exercise ( P < 0.05). However, when the hepatosplanchnic venous hemoglobin O2 saturation became low, the arterial and hepatosplanchnic venous blood lactate difference approached zero. Even with a marked reduction in its blood flow, exercise did not challenge the ability of the liver to maintain blood glucose homeostasis. However, it appeared that the contribution of the Cori cycle decreased, and the accumulation of lactate in blood became influenced by the reduced hepatosplanchnic blood flow.

PENGENDALIAN KADAR GLUKOSA DARAH OLEH TEH HIJAU DAN ATAU TEH DAUN MURBEI PADA TIKUS DIABETES

2010 ◽  
Vol 5 (2) ◽  
pp. 87
Author(s):  
Rusman Efendi ◽  
Evy Damayanthi ◽  
Lilik Kustiyah ◽  
Nastiti Kusumorini
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Green Tea ◽  
Glucose Level ◽  
Diabetic Rats ◽  
Feed Consumption ◽  
Font Size ◽  
High Prevalence ◽  
The Difference ◽  
Control Diabetes

<p class="MsoNormal" style="margin: 0cm 7.1pt 6pt 14.2pt; text-align: justify; text-indent: 1cm;"><span style="font-size: 10pt;">Diabetes mellitus is degeneratif disease with high prevalence that happens in many countries. Several studies had been done to control diabetes by using green tea, mullberry leaf  tea, and their mixture. The aim of this research was to analyze the influence of the administration green tea, mullbery leaf tea, and their mixtures to blood glucose level of diabetic rats both during 120 minutes after administration. This research had four phases, first to determine the best mullberry leaf tea, second to fourth phases respectively, determine turnover of blood glucose level on normal rats; attempt during 120 minutes on diabetic rats.  The result of research during 120 minutes have showed that blood glucose level on diabetic rats which were administered by green tea, mullberry leaf tea and their mixture is significantly difference with diabetic rats which were administered by water. Blood glucose level at baseline increased at 30<sup>th </sup>minutes and showed the difference significantly and then until 60<sup>th</sup> and 120<sup>th</sup> minutes and relatively stable. During 120 minutes after feed consumption, inhibition of blood glucose level occured increasingly on diabetic rats which were administered by green tea, mullberry leaf tea, and their mixture compared to diabetic rats which were administered by water.</span></p>

TOTAL POLYPHENOL CONTENT, FREE RADICAL SCAVENGING, ALPHA-GLUCOSIDASE INHIBITION CAPACITY, THE EFFICACY IN CONTROLLING BLOOD GLUCOSE OF DIABETIC RATS OF THE MIXTURE VOS EXTRACTED FROM THE LEAVES OF CLEISTOCALYX OPERCULATUS, PSIDIUM GUAJAVA AND NELUMBO NUCIFERA

2013 ◽  
pp. 50-55
Author(s):  
Tuyet Mai Truong ◽  
Thi Lam Nguyen ◽  
Lan Anh Pham ◽  
Hoang Kien Truong
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Radical Scavenging ◽  
Psidium Guajava ◽  
Free Radical Scavenging ◽  
Diabetic Mice ◽  
Cleistocalyx Operculatus ◽  
Prevention And Treatment ◽  
Treatment Of Diabetes ◽  
Alpha Glucosidase

Objective: Plant polyphenols have antioxidant capacity and alpha-glucosidase inhibition to supporting for prevention and treatment of diabetes. Materials and Method: Present study was conducted to determine the content of total polyphenols, free radical scavenging and alpha-glucosidase inhibition of the VOS mixture that extracted from leaves (Voi leaves - Cleistocalyx operculatus (V), Oi leaves - Psidium guajava (O), Sen leaves - Nelumbo nucifera (S)). Results: The efficacy of blood glucose controlling in diabetic mice was investigated. After 8 weeks of administration with 200 mg VOS/kg body weight and 400 mg VOS/kg body weight, VOS diabetic mice had significantly reduced blood glucose level as compared to control diabetic mice. VOS diabetic mice with 400 mg dosage are lower in blood glucose levels than that of the diabetic mice with 200 mg. Also, the significant reducing in HbA1c was observed in VOS diabetic mice as compared with control diabetic mice. Conclusion: VOS-product extracted from Cleistocalyx operculatus leaves, guava leaves, lotus leaves might be considered as a safe product and to be a potential product in the supporting of prevention and treatment of diabetes.

scholarly journals Effect of Phlorofucofuroeckol A and Dieckol Extracted from Ecklonia cava on Noise-induced Hearing Loss in a Mouse Model

Marine Drugs ◽  
2021 ◽  
Vol 19 (8) ◽  
pp. 443
Author(s):  
Hyunjun Woo ◽  
Min-Kyung Kim ◽  
Sohyeon Park ◽  
Seung-Hee Han ◽  
Hyeon-Cheol Shin ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hair Cell ◽  
Noise Exposure ◽  
Radical Scavenging ◽  
Threshold Shift ◽  
Ecklonia Cava ◽  
Control Group ◽  
Noise Induced Hearing Loss ◽  
Antioxidant Agents ◽  
Brainstem Response

One of the well-known causes of hearing loss is noise. Approximately 31.1% of Americans between the ages of 20 and 69 years (61.1 million people) have high-frequency hearing loss associated with noise exposure. In addition, recurrent noise exposure can accelerate age-related hearing loss. Phlorofucofuroeckol A (PFF-A) and dieckol, polyphenols extracted from the brown alga Ecklonia cava, are potent antioxidant agents. In this study, we investigated the effect of PFF-A and dieckol on the consequences of noise exposure in mice. In 1,1-diphenyl-2-picrylhydrazyl assay, dieckol and PFF-A both showed significant radical-scavenging activity. The mice were exposed to 115 dB SPL of noise one single time for 2 h. Auditory brainstem response(ABR) threshold shifts 4 h after 4 kHz noise exposure in mice that received dieckol were significantly lower than those in the saline with noise group. The high-PFF-A group showed a lower threshold shift at click and 16 kHz 1 day after noise exposure than the control group. The high-PFF-A group also showed higher hair cell survival than in the control at 3 days after exposure in the apical turn. These results suggest that noise-induced hair cell damage in cochlear and the ABR threshold shift can be alleviated by dieckol and PFF-A in the mouse. Derivatives of these compounds may be applied to individuals who are inevitably exposed to noise, contributing to the prevention of noise-induced hearing loss with a low probability of adverse effects.

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