scholarly journals The Effects of a Long-Term Physical Activity Intervention on Serum Uric Acid in Older Adults at Risk for Physical Disability

2014 ◽  
Vol 22 (1) ◽  
pp. 25-33 ◽  
Author(s):  
Kristen M. Beavers ◽  
Fang-Chi Hsu ◽  
Monica C. Serra ◽  
Veronica Yank ◽  
Marco Pahor ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
At Risk ◽  
Uric Acid ◽  
Health Education ◽  
Serum Uric Acid ◽  
Physical Disability ◽  
Moderate Intensity ◽  
Education Intervention ◽  
Health Education Intervention

Observational studies show a relationship between elevated serum uric acid (UA) and better physical performance and muscle function. The purpose of this paper was to determine whether regular participation in an exercise intervention, known to improve physical functioning, would result in increased serum UA. For this study, 424 older adults at risk for physical disability were randomized to participate in either a 12-mo moderate-intensity physical activity (PA) or a successful aging (SA) health education intervention. UA was measured at baseline, 6, and 12 mo (n= 368, 341, and 332, respectively). Baseline UA levels were 6.03 ± 1.52 mg/dl and 5.94 ± 1.55 mg/dl in the PA and SA groups, respectively. The adjusted mean UA at month 12 was 4.8% (0.24 mg/dl) higher in the PA compared with the SA group (p= .028). Compared with a health education intervention, a 1-yr PA intervention results in a modest increase in systemic concentration of UA in older adults at risk for mobility disability.

scholarly journals The Relation of Accelerometer-Measured Physical Activity and Serum Uric Acid Using the National Health and Nutrition Survey (NHANES) 2003–2004

2022 ◽  
Vol 3 ◽  
Author(s):  
Isaac D. Smith ◽  
Leanna M. Ross ◽  
Josi R. Gabaldon ◽  
Nicholas Holdgate ◽  
Carl F. Pieper ◽  
...  
Keyword(s):  
Physical Activity ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
National Health ◽  
Moderate Intensity ◽  
Accelerometer Data ◽  
Health And Nutrition ◽  
Non Linear ◽  
Objectively Measured ◽  
Objectively Measured Physical Activity

Objective: Gout is a crystal-induced inflammatory arthritis caused by elevated uric acid. Physical activity has the potential to reduce serum uric acid (SUA), thus improving the disease burden of gout. In this study, we examined the association of objectively-measured physical activity and SUA.Methods: A cross-sectional study was conducted using survey, laboratory, and accelerometer data from the 2003–2004 National Health and Nutrition Examination Survey (NHANES). SUA concentrations (mg/dL) were obtained during an initial exam, and then physical activity (kCal/day) was measured with 7 days of ActiGraph accelerometry in participants (n = 3,475) representative of the ambulatory, non-institutionalized US civilian population. Regression, including restricted cubic splines, was used to assess the relation of physical activity and SUA in bivariate and adjusted models. Covariates included age, gender, race/ethnicity, alcohol use, body mass index, renal function, and urate-lowering therapy.Results: In the bivariate model, physical activity was correlated with SUA concentrations and included a non-linear component (p < 0.01). In the adjusted model, linear splines were employed with a node at the SUA nadir of 5.37mg/dL; this occurred at 703 kCal/day of physical activity. The association of physical activity and SUA was negative from 0 to 703 kCal/day (p = 0.07) and positive >703 kCal/day (p < 0.01 for the change in slope).Conclusion: Physical activity and SUA are associated in a non-linear fashion, with a minimum estimated SUA at 703 kCal/day of objectively-measured physical activity. These findings raise intriguing questions about the use of physical activity as a potential adjunctive therapy in patients with gout, and further interventional studies are needed to elucidate the effects of moderate intensity exercise on SUA concentrations.

scholarly journals Use of Wearable Technology and Social Media to Improve Physical Activity and Dietary Behaviors among College Students: A 12-Week Randomized Pilot Study

2019 ◽  
Vol 16 (19) ◽  
pp. 3579 ◽  
Author(s):  
Zachary Pope ◽  
Daheia Barr-Anderson ◽  
Beth Lewis ◽  
Mark Pereira ◽  
Zan Gao
Keyword(s):  
Physical Activity ◽  
College Students ◽  
Social Media ◽  
Health Education ◽  
Health Behaviors ◽  
Cognitive Theory ◽  
Pilot Trial ◽  
Dietary Behaviors ◽  
Education Intervention ◽  
Health Education Intervention

College students demonstrate poor physical activity (PA) and dietary behaviors. We evaluated the feasibility of a combined smartwatch and theoretically based, social media-delivered health education intervention versus a comparison on improving college students’ health behaviors/outcomes. Thirty-eight students (28 female; Xage = 21.5 ± 3.4 years) participated in this two-arm, randomized 12-week pilot trial (2017–2018). Participants were randomized into: (a) experimental: Polar M400 use and twice-weekly social cognitive theory- and self-determination theory-based Facebook-delivered health education intervention; or (b) comparison: enrollment only in separate, but content-identical, Facebook intervention. Primary outcomes pertained to intervention feasibility. Secondary outcomes included accelerometer-estimated PA, physiological/psychosocial outcomes, and dietary behaviors. Intervention adherence was high (~86%), with a retention of 92.1%. Participants implemented health education tips 1–3 times per week. We observed experimental and comparison groups to have 4.2- and 1.6-min/day increases in moderate-to-vigorous PA (MVPA), respectively, at six weeks—partially maintained at 12 weeks. In both groups, similarly decreased body weight (experimental = −0.6 kg; comparison = −0.5 kg) and increased self-efficacy, social support, and intrinsic motivation were observed pre- and post-intervention. Finally, we observed small decreases in daily caloric consumption over time (experimental = −41.0 calories; comparison = −143.3). Both interventions were feasible/of interest to college students and demonstrated initial effectiveness at improving health behaviors/outcomes. However, smartwatch provision may not result in an additional benefit.

scholarly journals A Case for Promoting Movement Medicine: Preventing Disability in the LIFE Randomized Controlled Trial

2019 ◽  
Vol 74 (11) ◽  
pp. 1821-1827 ◽  
Author(s):  
Jason Fanning ◽  
W Jack Rejeski ◽  
Shyh-Huei Chen ◽  
Barbara J Nicklas ◽  
Michael P Walkup ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
At Risk ◽  
Health Education ◽  
Physical Activity Intervention ◽  
Controlled Trial ◽  
Vigorous Physical Activity ◽  
Treatment Regimens ◽  
To Receive

Abstract Background The movement profile of older adults with compromised function is unknown, as is the relationship between these profiles and the development of major mobility disability (MMD)—a critical clinical outcome. We first describe the dimensions of movement in older adults with compromised function and then examine whether these dimensions predict the onset of MMD. Methods Older adults at risk for MMD (N = 1,022, mean age = 78.7 years) were randomized to receive a structured physical activity intervention or health education control. We assessed MMD in 6-month intervals (average follow-up of 2.2 years until incident MMD), with activity assessed at baseline, 6-, 12- and 24-month follow-up via accelerometry. Results A principal components analysis of 11 accelerometer-derived metrics yielded three components representing lifestyle movement (LM), extended bouts of moderate-to-vigorous physical activity (MVPA), and stationary body posture. LM accounted for the greatest proportion of variance in movement (53%). Within health education, both baseline LM (HR = 0.74; 95% CI 0.62 to 0.88) and moderate-to-vigorous physical activity (HR = 0.69; 95% CI 0.54 to 0.87) were associated with MMD, whereas only LM was associated with MMD within physical activity (HR = 0.74; 95% CI 0.61 to 0.89). There were similar nonlinear relationships present for LM in both physical activity and health education (p < .04), whereby risk for MMD was lower among individuals with higher levels of LM. Conclusions Both LM and moderate-to-vigorous physical activity should be central in treatment regimens for older adults at risk for MMD. Trial Registration clinicaltrials.gov Identifier NCT01072500

Sign in / Sign up

Export Citation Format

Share Document