Colonization of Extended-Spectrum-β-Lactamase- and NDM-1-Producing Enterobacteriaceae among Pregnant Women in the Community in a Low-Income Country: a Potential Reservoir for Transmission of Multiresistant Enterobacteriaceae to Neonates
2015 ◽
Vol 59
(6)
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pp. 3652-3655
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Keyword(s):
ABSTRACTThe spread of extended-spectrum-β-lactamase-producingEnterobacteriaceae(ESBL-PE) in low-income countries, where the burden of neonatal sepsis is high, may have a serious impact on neonatal mortality rates. Given the potential for mother-to-child transmission of multiresistant bacteria, this study investigated the ESBL-PE rectal colonization among pregnant women at delivery in the community in Madagascar and estimated a prevalence of 18.5% (95% confidence interval, 14.5% to 22.6%). One strain ofKlebsiella pneumoniaeisolated was also a New Delhi metallo-β-lactamase-1 (NDM-1) producer.