Postantibiotic Effect of Tigecycline against 14 Gram-Positive Organisms
2008 ◽
Vol 53
(2)
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pp. 782-784
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Keyword(s):
ABSTRACT The in vitro postantibiotic effects (PAEs), postantibiotic sub-MIC effects (PA-SMEs), and sub-MIC effects of tigecycline were determined for 14 gram-positive and gram-negative organisms. The pneumococcal, staphylococcal, and enterococcal PAEs were 1.9 to 5.1, 2.9 to 5.7, and 3.9 to 6.1 h, respectively, and those for Haemophilus influenzae, Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, and Acinetobacter baumannii were 1.1 to 5.0, 1.9 to 2.1, 1.7 to 1.8, 1.0 to 1.7, and 0.7 to 3 h, respectively. The PA-SMEs (four times the MIC) ranged from 6.7 to >11 h for gram-positive organisms and from 2.3 to >11.3 h for gram-negative organisms.
2000 ◽
Vol 12
(3)
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pp. 218-223
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1998 ◽
Vol 42
(9)
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pp. 2365-2370
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1974 ◽
Vol 63
(7)
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pp. 1077-1084
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Keyword(s):
Keyword(s):
1987 ◽
Vol 31
(2)
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pp. 328-330
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Keyword(s):
2006 ◽
Vol 50
(1)
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pp. 385-387
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2020 ◽
2020 ◽