Two GacA-Dependent Small RNAs Modulate the Quorum-Sensing Response in Pseudomonas aeruginosa
2006 ◽
Vol 188
(16)
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pp. 6026-6033
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Keyword(s):
ABSTRACT In Pseudomonas aeruginosa, the GacS/GacA two-component system positively controls the quorum-sensing machinery and the expression of extracellular products via two small regulatory RNAs, RsmY and RsmZ. An rsmY rsmZ double mutant and a gacA mutant were similarly impaired in the synthesis of the quorum-sensing signal N-butanoyl-homoserine lactone, the disulfide bond-forming enzyme DsbA, and the exoproducts hydrogen cyanide, pyocyanin, elastase, chitinase (ChiC), and chitin-binding protein (CbpD). Both mutants showed increased swarming ability, azurin release, and early biofilm development.
2001 ◽
Vol 67
(4)
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pp. 1865-1873
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2003 ◽
Vol 185
(7)
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pp. 2080-2095
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2007 ◽
Vol 189
(14)
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pp. 5383-5386
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2015 ◽
Vol 60
(3)
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pp. 1676-1686
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2005 ◽
Vol 187
(1)
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pp. 37-44
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2008 ◽
Vol 52
(10)
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pp. 3648-3663
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