Haemolacria: a case of pseudomembranous conjunctivitis in a neonate

2020 ◽  
Vol 13 (6) ◽  
pp. e235110
Author(s):  
Michelle Marie Boffa ◽  
Amaris Spiteri

We report an unusual case of an 11-day-old neonate presenting with haemolacria on a background of sticky conjunctival discharge. This was secondary to Chlamydia pseudomembranous conjunctivitis which responded well to systemic erythromycin. Early appropriate treatment is important to prevent progression of the ophthalmic infection, which could lead to blindness, and to prevent other manifestations of neonatal chlamydial infection, particularly pneumonia, which could be fatal. Management also includes treating the mother and educating about sexually transmitted infections.

2021 ◽  
Vol 32 (6) ◽  
pp. 528-532
Author(s):  
Nur Gasmelsid ◽  
Benjamin CB Moran ◽  
Tom Nadarzynski ◽  
Rajul Patel ◽  
Elizabeth Foley

Patient demand on sexual health services in the United Kingdom is so high that many services have introduced online screening to accommodate more patients. There are concerns that these services may not be accessible to all. This service evaluation was undertaken to determine whether online screening is accessible by those patients most at need by comparing the demographics and number of asymptomatic chlamydial infections detected online and in clinic. No difference was found in the age nor level of deprivation, demonstrating that online services are an accessible way to screen for sexually transmitted infections without overburdening established services.


2021 ◽  
Vol 79 (1) ◽  
pp. 71-73
Author(s):  
Ângela Roda ◽  
João Borges-Costa

Trichomoniasis is one of the most common sexually transmitted infections worldwide. In women, Trichomonas vaginalis infection may present with vaginitis, cervicitis, or pelvic inflammatory disease, while in men it is mainly asymptomatic or causes mild and transient symptoms of urethritis, epididymitis, or prostatitis. In the past, little importance had been given to the impact of T. vaginalis infection on men’s health, since it was believed to be a self-limited condition without sequelae. However, there is growing evidence it is associated with more serious disorders in both men and women and efforts to diagnose and treat this parasitic infection have increased. Recent advances in testing for sexually transmitted diseases using multiplex molecular assays have increased diagnostic opportunities for T. vaginalis infection, especially in men, as detection of the parasite by traditional methods is much more challenging. We describe an unusual case of male urethritis caused by T. vaginalis observed in our consultation of Sexually Transmitted Infections.


2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Eugênia Leal de Figueiredo ◽  
Carolina Chaves Gama Aires ◽  
Bruno José Carvalho Macêdo Neres ◽  
Bruna Luna de Araújo ◽  
José Alcides Almeida de Arruda ◽  
...  

Mediastinitis is a rare, progressive, and destructive infectious process due to cervical or odontogenic infections, which, if not diagnosed early, may lead to several complications, including airway involvement and even an imminent risk of death. Herein, we report an unusual case of a 37-year-old male with a bilateral submandibular hard swelling after the left third molar extraction. After surgical intervention with submandibular drainage and antibiotic therapy, the infection persisted without explanation, since the patient was not hypertensive, did not have diabetes mellitus or sexually transmitted infections such as HIV or syphilis, and did not smoke or drink alcoholic beverages. A thoracic surgeon then intervened, treating the mediastinitis surgically by drainage, thus obtaining a significant improvement of the patient’s health. Mediastinitis is a serious condition. Clinicians and maxillofacial surgeons should be alert to make an immediate diagnosis and select the appropriate treatment in order to prevent worsening of the patient’s clinical condition.


2021 ◽  
pp. 55-62
Author(s):  
T.M. Tutchenko ◽  
O.A. Burka ◽  
I.F. Boyarchuk ◽  
A.V. Trampolska ◽  
V.V. Iavniuk ◽  
...  

This article presents modern data on epidemiological trends, pathogenesis, and mechanisms of persistence and acquisition of antibiotic resistance of the most common sexually transmitted infections (STIs): chlamydial infection, gonorrhea, trichomoniasis. Data on the frequency of chlamydial infection, gonorrhea, trichomoniasis detection in the DILA medical laboratory in the period from 2018–2020 are also presented.Analysis of epidemiological and microbiological studies indicates a significant increase in the STIs incidence in countries with high economic development and the need for constant revision of diagnostic and treatment approaches, based on new data on the pathogens physiology, mechanisms and levels of antibiotic resistance, possibilities of laboratory diagnostics. Analysis of the DILA data on the chlamydial infection, gonorrhea, trichomoniasis detection is coinciding with the world trends in the increase of their prevalence. At the same time, the analysis of the DILA data demonstrated an interesting clinical phenomenon as a presence of 2 STIs peaks in women: the first at 21–25 years and the second at 51–55 years old.Clinical manifestations of STIs are increasingly losing their typical features today. This indicates the need for a laboratory search for all common STIs in the region. Knowledge of the etiological factor of the inflammatory process allows choosing the correct antibiotic therapy and preventing the further development of antibiotic resistance. This article presents data on the various methods of STIs laboratory tests. Regular visits of women for cervical cancer screening are a good opportunity to screen for STIs. The ability to detect STIs in biomaterial in liquid cytology makes this option more accessible.Thus, since vaccines against common bacterial and protozoa STIs pathogens have not yet been developed, the promotion of hygiene of sexual behavior and timely detection of infected persons during examination or screening with subsequent etiopathogenetic treatment are the basis of the STIs control systems and their consequences prevention.


2005 ◽  
Vol 16 (1) ◽  
pp. 13-14 ◽  
Author(s):  
Max Chernesky ◽  
David Patrick ◽  
Rosanna Peeling

Excellent technologies have been developed to identify the specific microbial agents of chlamydia, gonorrhea, syphilis, herpes, chancroid, trichomoniasis, human papillomavirus and HIV infection. However, it is also crucial to recognize syndromes that may be caused by one or more sexually transmitted pathogens. When laboratory services are lacking or are inadequate to provide timely results to enable appropriate treatment, some patients must be managed and treated syndromically. Most Canadian laboratories should be able to provide diagnostic services to determine the etiology of syndromes such as cervicitis, urethritis, pelvic inflammatory disease, prostatitis, genital ulcers, sexually transmitted infection (STI)-related enteric infections, epididymitis, hepatitis, ophthalmia neonatorum, vulvovaginitis and vaginosis.


2002 ◽  
Vol 13 (9) ◽  
pp. 606-611 ◽  
Author(s):  
F M-T F Behets ◽  
J Andriamiadana ◽  
D Randrianasolo ◽  
D Rasamilalao ◽  
N Ratsimbazafy ◽  
...  

Women seeking care in Madagascar for genital discharge ( n =1066) were evaluated for syphilis seroreactivity; bacterial vaginosis (BV) and trichomoniasis. Chlamydial infection was assessed by ligase chain reaction (LCR) and by direct immunofluorescence (IF); gonorrhoea by direct microscopy, culture and LCR. Leucocytes were determined in endocervical smears and in urine using leucocyte esterase dipstick (LED). Gonococcal isolates were tested for minimal inhibitory concentrations. BV was found in 56%, trichomoniasis in 25%, and syphilis in 6% of the women. LCR detected gonorrhoea in 13% and chlamydial infection in 11% of the women. Detection of Gram(-) intracellular diplococci in endocervical smears, and gonococcal culture were respectively 23% and 57% sensitive and 98% and 100% specific compared to LCR. Chlamydia antigen detection by IF was 75% sensitive and 77% specific compared to LCR. Leucocytes in endocervical smears and LED testing lacked precision to detect gonococcal and chlamydial infections. Of 67 gonococcal strains evaluated, 19% were fully susceptible to penicillin, 33% to tetracycline; all were susceptible to ciprofloxacin, ceftriaxone, and spectinomycin. Patients who present with genital discharge in Madagascar should be treated syndromically for gonococcal and chlamydial infections and screened for syphilis. Gonorrhoea should be treated with ciprofloxacin.


Open Medicine ◽  
2011 ◽  
Vol 6 (1) ◽  
pp. 49-57 ◽  
Author(s):  
Ferenc Bánhidy ◽  
Istvan Dudás ◽  
Andrew Czeizel

AbstractHungarian Preconceptional Care includes the preconceptional screening of sexually transmitted infections/disorders (STD) and vaginal candidosis of potential mothers and pyospermia of potential fathers. The aim of this study was to evaluate the effect of this screening and treatment for the rate of preterm births. Clinical and subclinical vaginal candidiasis (asymptomatic candida colonisation), combination of STD and vaginal candidiasis, STD without vaginal candidiasis, finally women without STD and vaginal candidiasis as references were evaluated in 4,672 pregnant women. The association of STD in pregnant women with higher risk of preterm birth was confirmed. However, an association was also found between clinically diagnosed vaginal candidiasis, asymptomatic candida colonisation, and a higher risk for preterm births. This risk was reduced with clotrimazole treatment. However, pregnant women without recognized STD and/or vaginal candidiasis had a higher risk for preterm birth than pregnant women with STD or vaginal candidiasis after appropriate treatment. Thus the conclusion of the study is that the preconceptional screening of STD and vaginal candidiasis followed by appropriate treatment is important to prevent a certain part of preterm birth but it is necessary to improve the efficacy of the previously used methods for this screening.


2006 ◽  
Vol 17 (3) ◽  
pp. 193-195 ◽  
Author(s):  
K Manavi ◽  
A McMillan

Bacterial sexually transmitted infections (STIs) may be markers of high-risk sexual activity. Counselling for these infections provides an opportunity for promoting HIV testing. The aim of the present study was to compare the uptake of HIV testing between patients with gonorrhoea or chlamydial infections and those without a bacterial STI. A study on patients screened for chlamydial or gonococcal infections in the Department of Genitourinary (GU) Medicine, Edinburgh between 1 July 2002 and 30 June 2003. The overall uptake of HIV testing among patients screened for chlamydial and gonococcal infections was 2263 (37%) of 6184 and 2012 (44%) of 4583, respectively ( P < 0.0002). Uptake of HIV testing was significantly higher among uninfected patients: for chlamydial infection, 17% of 1857 infected patients versus 45% of 4327 uninfected patients ( P < 0.0002); and for gonococcal infection, 24% of 256 infected patients versus 45% of 4327 uninfected patients ( P < 0.0002). The policy of pre-test counselling needs to be redesigned in order to improve the uptake of HIV testing among patients with high-risk sexual activity.


2002 ◽  
Vol 6 (33) ◽  
Author(s):  

Consistent with other Western European states, the numbers and rates of bacterial and viral sexually transmitted infections (STIs) in England, Wales, and Northern Ireland have been increasing since the mid-1990s (1). Recently released figures (collected on the national KC60 statistical returns) on diagnoses made in genitourinary medicine (GUM) clinics in England, Wales, and Northern Ireland show that this increase has continued throughout 2001. In 2001, genital chlamydial infection became the most common STI seen in GUM clinics with a total of 71 055 diagnoses. This is the first time in 30 years that a bacterial STI has been the most commonly diagnosed STI and may reflect increased incidence as well as increased awareness and case-finding


2020 ◽  
pp. 1613-1621
Author(s):  
Henry J.C. de Vries ◽  
Charles J.N. Lacey

Anogenital lesions can be related to sexually transmitted infections, physiological variants that worry the patient, or dermatological conditions unrelated to infection. The clinical diagnostic approach is based on the colour of the lesion and the skin layer involved (epidermis, dermis, or subcutaneous fat compartment). A strong element of pattern recognition is involved in accurate diagnosis. This can only be learnt with experience, but is essential for determination of appropriate treatment. In this chapter the most common anogenital dermatological diagnoses are discussed using an approach based on the colour of the lesion and the skin layer involved. Many of these infections are asymptomatic, enabling ongoing transmission. Some sexually transmitted infections cause symptoms, especially in the anogenital region, and therefore need to be considered in the differential diagnosis of patients presenting with anogenital lesions.


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